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Nature Communications, ISSN 2041-1723, 2013, Volume 4, Issue 1, p. 2166
Isocitrate dehydrogenase (IDH) genes 1 and 2 are frequently mutated in acute myeloid leukaemia (AML), low-grade glioma, cholangiocarcinoma (CC) and... 
DNA METHYLATION | MAMMALIAN DNA | 5-METHYLCYTOSINE | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | PHENOTYPE | RETINOIC ACID RECEPTORS | ACUTE MYELOID-LEUKEMIA | MUTATIONS | 5-CARBOXYLCYTOSINE | DISCOVERY | Neoplasms - metabolism | Humans | Leukemia, Myeloid, Acute - metabolism | Gene Expression Regulation, Neoplastic | Cholangiocarcinoma - metabolism | Bone Neoplasms - pathology | Receptors, Retinoic Acid - genetics | Bone Neoplasms - metabolism | Glioma - metabolism | DNA-Binding Proteins - metabolism | Glioma - genetics | DNA Methylation | Neoplasms - genetics | Glioma - pathology | Trans-Activators - genetics | Chondrosarcoma - genetics | Chondrosarcoma - pathology | Bone Neoplasms - genetics | Bile Duct Neoplasms - genetics | Proto-Oncogene Proteins - metabolism | Central Nervous System Neoplasms - metabolism | Bile Duct Neoplasms - metabolism | Signal Transduction | Leukemia, Myeloid, Acute - pathology | Central Nervous System Neoplasms - genetics | Isocitrate Dehydrogenase - genetics | Proto-Oncogene Proteins - genetics | Receptors, Retinoic Acid - metabolism | DNA-Binding Proteins - genetics | Central Nervous System Neoplasms - pathology | Cholangiocarcinoma - pathology | Chondrosarcoma - metabolism | Cholangiocarcinoma - genetics | Isocitrate Dehydrogenase - metabolism | Trans-Activators - metabolism | Glutarates - metabolism | Bile Duct Neoplasms - pathology | Mutation | Neoplasms - pathology | Leukemia, Myeloid, Acute - genetics
Journal Article
American Journal of Surgical Pathology, ISSN 0147-5185, 10/2011, Volume 35, Issue 10, pp. e47 - e63
Significant progress has been made in understanding the molecular genetic alterations involved in sarcomagenesis. Cytogenetic and molecular studies have... 
malignant rhabdoid tumor | SMARCB1 | epithelioid sarcoma | schwannomatosis | SNF5 | soft tissue tumors | renal medullarycarcinoma | INI1 | SURGERY | NERVE SHEATH TUMOR | EXTRASKELETAL MYXOID CHONDROSARCOMA | PATHOLOGY | SOFT-TISSUE TUMORS | ROUND-CELL TUMOR | renal medullary carcinoma | DIFFERENTIATED SYNOVIAL SARCOMA | ATYPICAL TERATOID/RHABDOID TUMOR | OF-THE-LITERATURE | NATIONAL-WILMS-TUMOR | Myoepithelioma - metabolism | Kidney Neoplasms - genetics | Soft Tissue Neoplasms - diagnosis | Humans | Transcription Factors - deficiency | Carcinoma, Medullary - diagnosis | Carcinoma, Medullary - metabolism | Kidney Neoplasms - metabolism | DNA-Binding Proteins - deficiency | Kidney Neoplasms - diagnosis | DNA-Binding Proteins - metabolism | SMARCB1 Protein | Biomarkers, Tumor - metabolism | Sarcoma - diagnosis | Cytogenetic Analysis | Rhabdoid Tumor - metabolism | Sarcoma - genetics | Soft Tissue Neoplasms - genetics | Epithelioid Cells - pathology | Myoepithelioma - diagnosis | Chondrosarcoma - diagnosis | Chromosomal Proteins, Non-Histone - metabolism | Carcinoma, Medullary - genetics | Nerve Sheath Neoplasms - diagnosis | Soft Tissue Neoplasms - metabolism | Nerve Sheath Neoplasms - metabolism | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Chromosomal Proteins, Non-Histone - deficiency | Chromosomal Proteins, Non-Histone - genetics | Epithelioid Cells - metabolism | Immunohistochemistry - methods | Sarcoma - metabolism | Transcription Factors - metabolism | Rhabdoid Tumor - genetics | Rhabdoid Tumor - diagnosis
Journal Article
American Journal of Surgical Pathology, ISSN 0147-5185, 08/2008, Volume 32, Issue 8, pp. 1168 - 1174
Several previous studies have demonstrated the lack of SMARCB1/INI1 protein expression in only the malignant rhabdoid tumor (MRT). Several sarcoma groups are... 
EWS | Extraskeletal myxoid chondrosarcoma | Fusion gene transcript | SMARCB1/INI1 | Rhabdoid | SURGERY | BLADDER-CANCER | fusion gene transcript | AGGRESSIVE-BEHAVIOR | TIME QUANTITATIVE PCR | PATHOLOGY | MALIGNANT RHABDOID TUMORS | extraskeletal myxoid chondrosarcoma | GENE | rhabdoid | IMMUNOHISTOCHEMICAL ANALYSIS | CENTRAL-NERVOUS-SYSTEM | HSNF5/INI1 | MUTATIONS | ATYPICAL TERATOID/RHABDOID TUMORS | Immunohistochemistry | Translocation, Genetic | Neuroectodermal Tumors, Primitive - genetics | Prognosis | Chondrosarcoma - mortality | Humans | Gene Expression Regulation, Neoplastic | Rhabdoid Tumor - mortality | Sarcoma, Clear Cell - chemistry | DNA-Binding Proteins - analysis | Neuroectodermal Tumors, Primitive - chemistry | Rhabdoid Tumor - pathology | SMARCB1 Protein | Sarcoma - mortality | Chondrosarcoma - genetics | Chondrosarcoma - pathology | Liposarcoma, Myxoid - genetics | Sarcoma - genetics | Sarcoma, Clear Cell - genetics | Reproducibility of Results | Sarcoma, Ewing - chemistry | Down-Regulation | RNA-Binding Protein EWS - genetics | Rhabdoid Tumor - chemistry | Chondrosarcoma - chemistry | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Sarcoma - pathology | Chromosomal Proteins, Non-Histone - genetics | Sarcoma - chemistry | Rhabdoid Tumor - genetics | Oncogene Proteins, Fusion - genetics | Chromosomal Proteins, Non-Histone - analysis | Transcription Factors - analysis | Sarcoma, Ewing - genetics | Liposarcoma, Myxoid - chemistry
Journal Article
Journal Article
Journal Article
Journal Article
The Journal of Pathology, ISSN 0022-3417, 06/2006, Volume 209, Issue 2, pp. 157 - 165
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2012, Volume 7, Issue 11, p. e49705
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 08/2017, Volume 118, Issue 8, pp. 2182 - 2192
ABSTRACT Chondrosarcoma, the second‐most frequent primary bone malignancy, is generally more resistant to conventional chemotherapy and radiotherapy.... 
YAP | JQ1 | CHONDROSARCOMA | CELL CYCLE ARREST | p21 | CANCER-CELLS | APOPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | C-MYC | MECHANISMS | CELL BIOLOGY | LYMPHOMAGENESIS | THERAPY | DEGRADATION | PROGRESSION | BRD4 | Cell Cycle - genetics | Apoptosis - drug effects | Humans | Cell Survival - genetics | Cellular Senescence - drug effects | Apoptosis - genetics | Immunoblotting | Phosphoproteins - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - genetics | Flow Cytometry | RNA Interference | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Gene Expression Regulation, Neoplastic - drug effects | Gene Expression Regulation, Neoplastic - genetics | Cell Survival - drug effects | Cellular Senescence - genetics | Cell Proliferation - genetics | Signal Transduction - genetics | Phosphoproteins - genetics | Proto-Oncogene Proteins c-myc - metabolism | Azepines - pharmacology | Triazoles - pharmacology | Signal Transduction - drug effects | Chondrosarcoma - metabolism | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Cell Proliferation - drug effects | Proto-Oncogene Proteins c-myc - genetics | Adaptor Proteins, Signal Transducing - metabolism | Cell Cycle - drug effects | Proteins - antagonists & inhibitors | Epigenetic inheritance | Chemotherapy | T cells | Tumor proteins | Growth | Cancer | Cell proliferation | Regulations | GTP-binding protein | Chondrosarcoma | Senescence | p53 Protein | c-Myc protein | Lymphocytes T | Malignancy | Bone tumors | Myc protein | Cyclin D1 | Proteins | Cell growth | Bcl-x protein | Lymphocytes | Cell cycle | Inhibition | Radiation therapy | Yes-associated protein | Cyclin-dependent kinase inhibitor p21 | Inhibitors | Cyclin-dependent kinase inhibitor p27 | Bcl protein | In vitro methods and tests | Apoptosis
Journal Article