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Immunity, ISSN 1074-7613, 03/2013, Volume 38, Issue 3, pp. 555 - 569
Monocyte-derived macrophages are essential for recovery after spinal cord injury, but their homing mechanism is poorly understood. Here, we show that although... 
ECTO-5'-NUCLEOTIDASE CD73 | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | DENDRITIC CELLS | MICROGLIA | REGENERATION | MONOCYTES | CNS | CENTRAL-NERVOUS-SYSTEM | IMMUNOLOGY | DIVERGENT | EXPRESSION | 5'-Nucleotidase - antagonists & inhibitors | 5'-Nucleotidase - genetics | Leukocyte Common Antigens - metabolism | Meninges - immunology | Spinal Cord - metabolism | Choroid Plexus - metabolism | Choroid Plexus - immunology | Monocytes - metabolism | Green Fluorescent Proteins - genetics | Monocytes - immunology | Spinal Cord Injuries - genetics | Cell Movement - genetics | Meninges - metabolism | Cell Movement - immunology | Leukocyte Common Antigens - immunology | Flow Cytometry | 5'-Nucleotidase - immunology | Gene Expression - immunology | Antigens, Ly - metabolism | Vascular Cell Adhesion Molecule-1 - genetics | Receptors, Chemokine - genetics | Macrophages - immunology | Green Fluorescent Proteins - metabolism | Vascular Cell Adhesion Molecule-1 - immunology | Blood-Brain Barrier - immunology | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Integrin alpha4beta1 - genetics | Receptors, Chemokine - immunology | Reverse Transcriptase Polymerase Chain Reaction | Adenosine Diphosphate - pharmacology | Blood-Brain Barrier - metabolism | Mice, Knockout | Integrin alpha4beta1 - immunology | Monocytes - drug effects | Spinal Cord - immunology | Microscopy, Confocal | Macrophages - metabolism | Animals | Antigens, Ly - immunology | Macrophages - drug effects | Spinal Cord Injuries - immunology | Mice | Adenosine Diphosphate - analogs & derivatives | CX3C Chemokine Receptor 1 | Spinal Cord Injuries - cerebrospinal fluid | Macrophages | Enzymes | Spinal cord injuries | Statistical analysis | Cytokines | Rodents | Recruitment | Index Medicus
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2013, Volume 110, Issue 6, pp. 2264 - 2269
Journal Article
Nature Medicine, ISSN 1078-8956, 08/2017, Volume 23, Issue 8, pp. 997 - 1003
The choroid plexus epithelium (CPE) secretes higher volumes of fluid (cerebrospinal fluid, CSF) than any other epithelium and simultaneously functions as the... 
MEDICINE, RESEARCH & EXPERIMENTAL | NERVOUS-SYSTEM | SPAK | CATION-CHLORIDE COTRANSPORTERS | OSR1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | MECHANISMS | RECEPTOR 4 | CELL BIOLOGY | BUMETANIDE | INTRAVENTRICULAR HEMORRHAGE | STRESS | KINASES | Immunohistochemistry | Immunoprecipitation | Rats, Wistar | NF-kappa B - immunology | Choroid Plexus - immunology | Immunoblotting | Cerebral Hemorrhage - immunology | Hydrocephalus - metabolism | Gene Knockdown Techniques | Choroid Plexus - drug effects | Choroid Plexus - secretion | Thiocarbamates - pharmacology | Cerebral Ventricles | Proline - pharmacology | Protein-Serine-Threonine Kinases - metabolism | Solute Carrier Family 12, Member 2 - metabolism | Acetazolamide - pharmacology | Proline - analogs & derivatives | Diuretics - pharmacology | Rats | Toll-Like Receptor 4 - genetics | Hydrocephalus - etiology | Inflammation | Toll-Like Receptor 4 - immunology | Antioxidants - pharmacology | Cerebrospinal Fluid - secretion | Gene Knockout Techniques | Sulfonamides - pharmacology | Blotting, Western | Bumetanide - pharmacology | Animals | Hydrocephalus - immunology | Salicylanilides - pharmacology | Cerebral Hemorrhage - complications | Choroid plexus | Drugs | Brain | Regulatory agencies | Hydrocephalus | Pathogenesis | Cerebral ventricles | Central nervous system | Ventricles (cerebral) | Inflammatory response | Cerebrospinal fluid | Hemorrhage | Immunosuppressive agents | Proteins | Toll-like receptors | Bumetanide | NF-κB protein | Secretion | Chloride transport | Reabsorption | TLR4 protein | Epithelium | Immune systems | Transporter | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2003, Volume 100, Issue 14, pp. 8389 - 8394
Cerebrospinal fluid (CSF) from healthy individuals contains between 1,000 and 3,000 leukocytes per ml. Little is known about trafficking patterns of leukocytes... 
T lymphocytes | Choroid plexus | Biological Sciences | Venules | Lymphocytes | Memory | Central nervous system | Leukocytes | Endothelial cells | Blood | Cell adhesion molecules | MULTIPLE-SCLEROSIS LESIONS | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | INTERCELLULAR-ADHESION MOLECULE-1 | HUMAN BRAIN | MULTIDISCIPLINARY SCIENCES | IMMUNE SURVEILLANCE | IN-VIVO | CENTRAL-NERVOUS-SYSTEM | PERIPHERAL-BLOOD | ENDOTHELIAL SELECTINS | EXPRESSION | Endothelium, Vascular - cytology | Membrane Glycoproteins - analysis | Humans | Middle Aged | Receptors, Chemokine - analysis | Child, Preschool | Choroid Plexus - immunology | Infant | Male | Cerebrospinal Fluid - cytology | Endothelium, Vascular - chemistry | Cerebrospinal Fluid - immunology | CD4-Positive T-Lymphocytes - immunology | Choroid Plexus - blood supply | Choroid Plexus - cytology | Membrane Glycoproteins - physiology | Aged, 80 and over | Adult | Female | Lymphocyte Function-Associated Antigen-1 - analysis | P-Selectin - analysis | Child | Arachnoid - immunology | Endothelium, Vascular - immunology | Intercellular Adhesion Molecule-1 - analysis | Lymphocyte Function-Associated Antigen-1 - physiology | CD4-Positive T-Lymphocytes - chemistry | Arachnoid - blood supply | Intercellular Adhesion Molecule-1 - physiology | Subarachnoid Space | CD4-Positive T-Lymphocytes - cytology | Receptors, CCR7 | Immunophenotyping | Cell Adhesion | P-Selectin - physiology | Venules - chemistry | Arachnoid - cytology | Receptors, Chemokine - physiology | Adolescent | Aged | E-Selectin - analysis | Cell Movement | Brain | Neurology | Cellular biology | Index Medicus
Journal Article
Journal Article
Journal of Cerebral Blood Flow & Metabolism, ISSN 0271-678X, 1/2012, Volume 32, Issue 1, pp. 93 - 104
The invasion of inflammatory cells occurring after ischemic or traumatic brain injury (TBI) has a detrimental effect on neuronal survival and functional... 
traumatic brain injury | monocytes | blood-cerebrospinal fluid barrier | CC chemokines | choroid plexus | CELLS | INTESTINAL EPITHELIA | RECEPTOR | NEUROSCIENCES | CHEMOATTRACTANT PROTEIN-1 MCP-1 | TRAUMATIC BRAIN-INJURY | ENDOCRINOLOGY & METABOLISM | SALMONELLA-TYPHIMURIUM | CENTRAL-NERVOUS-SYSTEM | CHOROID-PLEXUS | RAT-BRAIN | HEMATOLOGY | EXPRESSION | Basement Membrane - ultrastructure | Chemokine CCL2 - immunology | Chemokine CCL2 - secretion | Monocytes - cytology | Rats, Long-Evans | Choroid Plexus - immunology | Male | Monocytes - immunology | Choroid Plexus - ultrastructure | Intercellular Junctions - immunology | Cerebrospinal Fluid - cytology | Blood-Brain Barrier - ultrastructure | Cerebrospinal Fluid - immunology | Choroid Plexus - blood supply | Brain Injuries - immunology | Brain Injuries - blood | Real-Time Polymerase Chain Reaction | Disease Models, Animal | Monocytes - ultrastructure | Neutrophil Infiltration - immunology | Microscopy, Electron, Transmission | Blood-Brain Barrier - immunology | Enzyme-Linked Immunosorbent Assay | Cells, Cultured | Rats | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Basement Membrane - immunology | Animals | Brain Injuries - cerebrospinal fluid | Epithelial Cells - immunology | Chemotaxis, Leukocyte - immunology | Intercellular Junctions - ultrastructure | Index Medicus | blood–cerebrospinal fluid barrier | Original
Journal Article
Nature Medicine, ISSN 1078-8956, 03/2019, Volume 25, Issue 3, pp. 496 - 506
Apolipoprotein-E (ApoE) has been implicated in Alzheimer's disease, atherosclerosis, and other unresolvable inflammatory conditions but a common mechanism of... 
MEDICINE, RESEARCH & EXPERIMENTAL | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEUROFIBRILLARY PATHOLOGY | ATHEROSCLEROSIS | NEURODEGENERATION | LASER-CAPTURE MICRODISSECTION | APOLIPOPROTEIN-E | CELL BIOLOGY | IMMUNE | A-BETA | MICE | FACTOR-H BINDS | Complement C5 | Complement C1q - immunology | Humans | Middle Aged | Choroid Plexus - immunology | Male | Leukocytes | Cognitive Dysfunction - immunology | Carotid Artery Diseases - pathology | Aged, 80 and over | Female | Plaque, Amyloid - immunology | Carotid Artery Diseases - immunology | Atherosclerosis - pathology | Atherosclerosis - immunology | Plaque, Amyloid - pathology | Choroid Plexus - pathology | Aorta - immunology | Cognitive Dysfunction - pathology | Mice, Knockout, ApoE | Aorta - pathology | Complement Pathway, Classical - immunology | Animals | Apolipoproteins E - immunology | Carotid Arteries - immunology | Brain - pathology | Amyloid beta-Peptides - immunology | Aged | Carotid Arteries - pathology | RNA, Small Interfering | Antigen-Antibody Complex - immunology | Protein Isoforms - immunology | Brain - immunology | Microscopy, Fluorescence | Cogeneration power plants | Analysis | Atherosclerosis | Lipids | Research | Apolipoproteins | Alzheimer's disease | Choroid plexus | Complex formation | Cognitive ability | Complement | Inflammation | siRNA | Ribonucleic acid--RNA | Arteries | Microglia | White blood cells | Proteins | Complement component C1q | Immune checkpoint | Apolipoprotein E | Arteriosclerosis | Isoforms | Attenuation | Infiltration | Plaques | Index Medicus
Journal Article