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Science Translational Medicine, ISSN 1946-6234, 10/2015, Volume 7, Issue 308, pp. 308re8 - 308re8
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 03/2015, Volume 93, pp. 42 - 50
Combining tacrine with trolox in a single molecule, novel multifunctional hybrids have been designed and synthesized. All these hybrids showed ChE inhibitory... 
Antioxidant | Trolox | Alzheimer's disease | Hepatotoxicity | Tacrine | Cholinesterase | NO DONOR | TARGET-DIRECTED LIGANDS | OXIDATIVE STRESS | CHEMISTRY, MEDICINAL | RAT HEPATOCYTES | CHOLINESTERASE-INHIBITORS | IN-VITRO | AMYLOID-BETA | ACETYLCHOLINESTERASE INHIBITORS | DERIVATIVES | Cholinesterase Inhibitors - pharmacokinetics | Male | Cholinesterase Inhibitors - chemical synthesis | PC12 Cells | Tacrine - adverse effects | Tacrine - pharmacology | Neuroprotective Agents - pharmacology | Tacrine - pharmacokinetics | Chromans - pharmacokinetics | Chromans - pharmacology | Neuroprotective Agents - pharmacokinetics | Swine | Picrates - chemistry | Drug Design | Molecular Structure | Biphenyl Compounds - chemistry | Neuroprotective Agents - adverse effects | Chromans - chemistry | Tacrine - chemistry | Cell Survival - drug effects | Chemical and Drug Induced Liver Injury - prevention & control | Alzheimer Disease - drug therapy | Rats | Alzheimer Disease - enzymology | Antioxidants - chemical synthesis | Antioxidants - pharmacology | Blood-Brain Barrier - metabolism | Chromans - adverse effects | Neuroprotective Agents - chemical synthesis | Animals | Cholinesterase Inhibitors - pharmacology | Alzheimer Disease - metabolism | Cholinesterase Inhibitors - adverse effects | Antioxidants - adverse effects | Molecular Docking Simulation | Kinetics | Antioxidants - pharmacokinetics | In Vitro Techniques | Antioxidants | Enzyme inhibitors | Drug therapy | Analysis | Index Medicus
Journal Article
Journal of Biomedical Nanotechnology, ISSN 1550-7033, 2012, Volume 8, Issue 2, pp. 316 - 321
The aim of this work was to perform a pilot study on the safety and efficacy of nanoparticle formulation for cosmetic application. The encapsulated actives in... 
Antioxidants | Nanoparticles | Alternative methods | Wrinkles | Efficacy | Safety | Photoprotection | MATERIALS SCIENCE, BIOMATERIALS | NANOSCIENCE & NANOTECHNOLOGY | Alternative Methods | CARRIERS | DELIVERY | SOLID LIPID NANOPARTICLES | SLN | CYTOTOXICITY | NIH 3T3 Cells | Vitamin A - chemistry | Skin Irritancy Tests | Antioxidants - chemistry | Nanoparticles - chemistry | Skin - metabolism | Vitamin A - analogs & derivatives | Humans | Middle Aged | Cosmetics - chemistry | Nanoparticles - adverse effects | Vitamin A - administration & dosage | Cosmetics - administration & dosage | Linseed Oil - adverse effects | Adult | Chromans - administration & dosage | Tocopherols - chemistry | Ubiquinone - adverse effects | Chromans - chemistry | Cell Survival - drug effects | Ubiquinone - administration & dosage | Tocopherols - administration & dosage | Skin Aging - drug effects | Ubiquinone - analogs & derivatives | Linseed Oil - chemistry | Sunscreening Agents - adverse effects | Cosmetics - adverse effects | Particle Size | Chromans - adverse effects | Skin - chemistry | Animals | Chickens | Sunscreening Agents - chemistry | Antioxidants - administration & dosage | Tocopherols - adverse effects | Antioxidants - adverse effects | Mice | Mice, Inbred BALB C | Nanoparticles - administration & dosage | Vitamin A - adverse effects | Linseed Oil - administration & dosage | Skin - drug effects | Ubiquinone - chemistry | Hydrogen-Ion Concentration
Journal Article
Journal Article
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 2009, Volume 64, Issue 4, pp. 259 - 263
Abstract Objectives The iron chelator dexrazoxane has been shown to significantly reduce anthracycline-induced cardiac toxicity in several randomized... 
Internal Medicine | Medical Education | Antioxidants | Dexrazoxane | Anthracyclines | Free radicals | Epirubicin | MEDICINE, RESEARCH & EXPERIMENTAL | ADVANCED BREAST-CANCER | ANTHRACYCLINE-BASED CHEMOTHERAPY | CARDIOPROTECTIVE AGENT ICRF-187 | COMPLEXES | DOXORUBICIN-CONTAINING THERAPY | SCAVENGING CAPACITY | CARDIOTOXICITY | REDUCTION | ACUTE LYMPHOBLASTIC-LEUKEMIA | ADRIAMYCIN | PHARMACOLOGY & PHARMACY | Free Radical Scavengers - pharmacology | Cytarabine - therapeutic use | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Cytarabine - adverse effects | Methotrexate - therapeutic use | Cyclophosphamide - adverse effects | Cyclophosphamide - therapeutic use | Razoxane - pharmacology | Glutathione - pharmacology | Bleomycin - therapeutic use | Chromans - pharmacology | Time Factors | Female | Lymphoma, Non-Hodgkin - drug therapy | Etoposide - adverse effects | Prednisone - adverse effects | Etoposide - therapeutic use | Antioxidants - pharmacology | Bleomycin - adverse effects | Methotrexate - adverse effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Uric Acid - pharmacology | Vincristine - therapeutic use | Epirubicin - therapeutic use | Vincristine - adverse effects | Prednisone - therapeutic use | Epirubicin - adverse effects | Lymphoma, Non-Hodgkin - physiopathology | Index Medicus
Journal Article
Diabetes Care, ISSN 0149-5992, 03/2002, Volume 25, Issue 3, pp. 542 - 549
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 09/2017, Volume 232, Issue 9, pp. 2461 - 2468
In live cell imaging of fluorescent proteins, phototoxicity of the excitation light can be problematical. Cell death is obvious, but reduced cell viability can... 
MITOSIS | CYTOKINESIS | PHYSIOLOGY | PRACTICAL CONSIDERATIONS | CENTROSOME |