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Toxicology, ISSN 0300-483X, 2006, Volume 217, Issue 2, pp. 213 - 220
Journal Article
Circulation Research: Journal of the American Heart Association, ISSN 0009-7330, 08/2003, Volume 93, Issue 4, pp. 311 - 320
ABSTRACT—Homocysteine (Hcy) is an independent risk factor for cardiovascular disease. Monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8) are... 
Monocyte chemoattractant protein-1 | Monocytes | Homocysteine | Interleukin-8 | Atherosclerosis | homocysteine | atherosclerosis | monocytes | ENDOTHELIAL-CELL INJURY | OXIDATIVE STRESS | CARDIAC & CARDIOVASCULAR SYSTEMS | OXIDANT STRESS | monocyte chemoattractant protein-1 | RISK FACTOR | PLASMA HOMOCYST(E)INE | interleukin-8 | VASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | ATHEROMATOUS PLAQUES | HEMATOLOGY | NF-KAPPA-B | T-LYMPHOCYTES | Interleukin-8 - genetics | Reactive Oxygen Species - metabolism | Chemokine CCL2 - secretion | Monocytes - cytology | Humans | Dimethyl Sulfoxide - pharmacology | Monocytes - metabolism | RNA, Messenger - metabolism | Pyrrolidines - pharmacology | Dose-Response Relationship, Drug | Thiocarbamates - pharmacology | Chromans - pharmacology | Time Factors | Homocysteine - pharmacology | Indoles - pharmacology | Interleukin-8 - secretion | Flavonoids - pharmacology | RNA, Messenger - drug effects | RNA, Messenger - genetics | Cells, Cultured | Enzyme Inhibitors - pharmacology | Chemokine CCL2 - genetics | Imidazoles - pharmacology | Tyrphostins - pharmacology | Antioxidants - pharmacology | Onium Compounds - pharmacology | Sulfonamides - pharmacology | Naphthalenes - pharmacology | Gene Expression Regulation - drug effects | Monocytes - drug effects | Genistein - pharmacology | Pyridines - pharmacology | Thiazoles - pharmacology | Thiazolidinediones
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 08/2007, Volume 35, Issue 8, pp. 1308 - 1314
Hepatic uptake carriers of the organic anion-transporting peptide (OATP) family of solute carriers are more and more recognized as being involved in hepatic... 
RAT | SEVERE RHABDOMYOLYSIS | COMBINATION THERAPY | LIVER | PHARMACOLOGY & PHARMACY | CERIVASTATIN | HEPATIC-UPTAKE | TRANSPLANT RECIPIENTS | ROSUVASTATIN | POLYPEPTIDE | FAMILY | Organic Anion Transporters, Sodium-Independent - genetics | Fatty Acids, Monounsaturated - pharmacology | Cricetulus | Hypolipidemic Agents - metabolism | Hypoglycemic Agents - metabolism | Taurocholic Acid - metabolism | Humans | Hepatocytes - metabolism | Simvastatin - pharmacology | Organic Anion Transporters - metabolism | Chromans - metabolism | Hepatocytes - cytology | Indoles - metabolism | Organic Anion Transporters - genetics | Drug Interactions | Anticholesteremic Agents - metabolism | Chromans - pharmacology | Fatty Acids, Monounsaturated - metabolism | Organic Anion Transporters, Sodium-Independent - metabolism | Indoles - pharmacology | Biological Transport - drug effects | Thiazolidinediones - pharmacology | Hepatocytes - drug effects | Solute Carrier Organic Anion Transporter Family Member 1B3 | CHO Cells | Pravastatin - pharmacology | Recombinant Proteins - metabolism | Taurocholic Acid - pharmacology | Cell Line | Cricetinae | Pravastatin - metabolism | Simvastatin - metabolism | Gemfibrozil - pharmacokinetics | Gemfibrozil - pharmacology | Hypolipidemic Agents - pharmacology | Thiazolidinediones - metabolism | Hypoglycemic Agents - pharmacology | Animals | Estrone - analogs & derivatives | Estrone - metabolism | Protein Binding | Fatty Acids, Monounsaturated - pharmacokinetics | Indoles - pharmacokinetics | Kinetics | Solute Carrier Organic Anion Transporter Family Member 1b1 | Anticholesteremic Agents - pharmacology | Gemfibrozil - metabolism
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 01/2000, Volume 28, Issue 1, pp. 55 - 63
Reactive oxygen species have been shown to be involved in the mutagenicity, clastogenicity, and apoptosis of mammalian cells treated with arsenic or cadmium.... 
Excision repair | Reactive oxygen species | Peroxynitrite | Hydrogen peroxide | Free radicals | Nitric oxide | nitric oxide | free radicals | OXIDATIVE STRESS | peroxynitrite | NITRIC-OXIDE SYNTHASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | hydrogen peroxide | SODIUM ARSENITE | STRAND BREAKS | excision repair | CHINESE-HAMSTER CELLS | reactive oxygen species | HEAT-SHOCK RESPONSE | L-ARGININE | ENDOCRINOLOGY & METABOLISM | HYDROGEN-PEROXIDE | WELL WATER | MALIGNANT NEOPLASMS | Cadmium Chloride - toxicity | Catalase - pharmacology | Free Radical Scavengers - pharmacology | Amitrole - pharmacology | Mutagens - toxicity | Citrulline - analogs & derivatives | Reactive Oxygen Species - metabolism | Nitric Oxide Synthase - antagonists & inhibitors | Endothelium, Vascular - drug effects | Molsidomine - analogs & derivatives | Thiourea - pharmacology | Endothelium, Vascular - chemistry | Phenanthrolines - pharmacology | Chromans - pharmacology | Arsenites - toxicity | Cattle | Superoxides - metabolism | Nitric Oxide Donors - pharmacology | Superoxide Dismutase - pharmacology | N-Glycosyl Hydrolases - pharmacology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Sodium Selenite - pharmacology | Antioxidants - pharmacology | Onium Compounds - pharmacology | Hydrogen Peroxide - metabolism | Nitroarginine - pharmacology | Nitrates - metabolism | Bacterial Proteins - pharmacology | DNA-Formamidopyrimidine Glycosylase | Animals | Citrulline - pharmacology | Ditiocarb - pharmacology | Escherichia coli Proteins | Sodium Compounds - toxicity | Uric Acid - pharmacology | Molsidomine - pharmacology | Thiomalates - pharmacology | Aorta - cytology | DNA Damage | Nitric Oxide - metabolism | Thiourea - analogs & derivatives | formamidopyrimidine-DNA glycosylase | formamidopyrimidine | 3-morpholinosydnonimine | 8-oxoguanine
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 04/2001, Volume 276, Issue 17, pp. 13750 - 13755
Journal Article
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 07/2011, Volume 45, Issue 1, pp. 111 - 119
Journal Article
Pflügers Archiv - European Journal of Physiology, ISSN 0031-6768, 7/2015, Volume 467, Issue 7, pp. 1431 - 1443
Journal Article
Biochemical Journal, ISSN 0264-6021, 09/2013, Volume 454, Issue 2, pp. 201 - 208
NAC (N-acetyl-L-cysteine) is commonly used to identify and test ROS (reactive oxygen species) inducers, and to inhibit ROS. In the present study, we identified... 
Catalase | N-acetyl-L-cysteine (NAC) | Proteasome inhibitor | Reactive oxygen species (ROS) | Forkhead box protein M1 (FOXM1) | CANCER-CELLS | TARGET | APOPTOSIS | OXIDATIVE STRESS | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | reactive oxygen species (ROS) | ENDOPLASMIC-RETICULUM STRESS | BORTEZOMIB | FOXM1 | INACTIVATION | proteasome inhibitor | LACTACYSTIN | catalase | Free Radical Scavengers - pharmacology | Oxidants - pharmacology | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Humans | Acetylcysteine - metabolism | Proteasome Inhibitors - chemistry | Proteasome Inhibitors - metabolism | Viral Proteins - metabolism | Antineoplastic Agents, Phytogenic - antagonists & inhibitors | Chromans - metabolism | Proteasome Endopeptidase Complex - drug effects | Chromans - pharmacology | Dioxolanes - pharmacology | Forkhead Transcription Factors - metabolism | Forkhead Transcription Factors - antagonists & inhibitors | Ubiquitinated Proteins - metabolism | Recombinant Proteins - metabolism | Recombinant Proteins - antagonists & inhibitors | Free Radical Scavengers - metabolism | Proteasome Inhibitors - pharmacology | Catalase - genetics | Chromans - antagonists & inhibitors | Hydrogen Peroxide - pharmacology | Viral Proteins - genetics | Oxidants - antagonists & inhibitors | Dioxolanes - antagonists & inhibitors | Forkhead Transcription Factors - genetics | Catalase - metabolism | Reactive Oxygen Species - antagonists & inhibitors | Protein Stability - drug effects | Acetylcysteine - pharmacology | Cell Line, Tumor | Cytomegalovirus - enzymology | Proteasome Endopeptidase Complex - metabolism | Antineoplastic Agents, Phytogenic - pharmacology | Forkhead Box Protein M1 | Hydrogen Peroxide - antagonists & inhibitors | N-acetyl-l-cysteine (NAC)
Journal Article
European Journal of Neuroscience, ISSN 0953-816X, 01/1999, Volume 11, Issue 1, pp. 327 - 334
Evidence has accumulated that Zn 2+ plays a central role in neurodegenerative processes following brain injuries including ischaemia or epilepsy. In the... 
cortical cell culture | apoptosis | ischaemia | necrosis | zinc | oxidative stress | Ischaemia | Oxidative stress | Cortical cell culture | Zinc | Apoptosis | Necrosis | GLUTAMATE NEUROTOXICITY | ZINC NEUROTOXICITY | DEATH | NEUROSCIENCES | INHIBITION | NITRIC-OXIDE | NMDA | RECEPTORS | BRAIN | METHYL-D-ASPARTATE | Neurons - pathology | Apoptosis - drug effects | Cerebral Cortex - cytology | Nerve Degeneration - chemically induced | Nerve Degeneration - metabolism | Brain-Derived Neurotrophic Factor - pharmacology | Zinc - pharmacokinetics | Neurons - ultrastructure | Chromans - pharmacology | Amino Acid Chloromethyl Ketones - pharmacology | Lipid Peroxidation - drug effects | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Free Radicals - metabolism | Female | Neurons - metabolism | Mitochondrial Swelling | Dopamine Agonists - pharmacology | Insulin - pharmacology | Kainic Acid - pharmacology | Cells, Cultured | Excitatory Amino Acid Agonists - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Antioxidants - pharmacology | Microscopy, Electron | Hypoglycemic Agents - pharmacology | Drug Synergism | Neurotoxins - pharmacology | Pregnancy | Animals | Cysteine Proteinase Inhibitors - pharmacology | alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid - pharmacology | 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine - pharmacology | Zinc - toxicity | Mice | Oxidative Stress - drug effects | Dizocilpine Maleate - pharmacology | Oligopeptides - pharmacology
Journal Article