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1. Full Text The molecular basis of T cell acute lymphoblastic leukemia
by Van Vlierberghe, Pieter and Ferrando, Adolfo
Journal of Clinical Investigation, ISSN 0021-9738, 10/2012, Volume 122, Issue 10, pp. 3398 - 3406
T cell acute lymphoblastic leukemias (T-ALLs) arise from the malignant transformation of hematopoietic progenitors primed toward T cell development, as result... 
MEDICINE, RESEARCH & EXPERIMENTAL | EARLY TREATMENT RESPONSE | ACTIVATING FLT3 MUTATIONS | GAMMA-SECRETASE INHIBITORS | PEDIATRIC-ONCOLOGY-GROUP | TUMOR-SUPPRESSOR | OF-FUNCTION MUTATIONS | CHROMOSOMAL TRANSLOCATION | GENE-EXPRESSION SIGNATURES | TRANSGENIC MICE | HOX11L2 EXPRESSION | Prognosis | Humans | Neoplasm Proteins - physiology | Transcriptome | Hematopoietic Stem Cells - pathology | Chromatin Assembly and Disassembly - genetics | Molecular Targeted Therapy | Cyclin-Dependent Kinase Inhibitor p16 - physiology | Cell Transformation, Neoplastic - genetics | Tumor Suppressor Proteins - genetics | Cell Cycle Proteins - genetics | T-Lymphocytes - pathology | Neoplasm Proteins - genetics | Transcription Factors - physiology | Receptors, Notch - physiology | Signal Transduction - genetics | Genes, p16 | Homeodomain Proteins - genetics | Cell Lineage | Tumor Suppressor Proteins - physiology | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - classification | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - etiology | Signal Transduction - physiology | Homeodomain Proteins - physiology | Cell Cycle Proteins - physiology | Chromatin Assembly and Disassembly - physiology | Gene mutations | Physiological aspects | Genetic aspects | Research | Acute lymphocytic leukemia | T cells | Health aspects | Risk factors | Review Series
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2. Full Text Mechanisms of action and regulation of ATP-dependent chromatin-remodelling complexes
by Clapier, Cedric R and Iwasa, Janet and Cairns, Bradley R and Peterson, Craig L
Nature Reviews Molecular Cell Biology, ISSN 1471-0072, 07/2017, Volume 18, Issue 7, pp. 407 - 422
Cells utilize diverse ATP-dependent nucleosome-remodelling complexes to carry out histone sliding, ejection or the incorporation of histone variants,... 
EXTRANUCLEOSOMAL DNA | H4 TAIL | CRYSTAL-STRUCTURE | IN-VIVO | DNA TRANSLOCATION | PHD FINGER | DOUBLE-STRAND BREAK | TRANSCRIPTION FACTOR | NUCLEOSOME CORE PARTICLE | HISTONE VARIANT H2A.Z | CELL BIOLOGY | Animals | Adenosine Triphosphate - metabolism | Humans | Nucleosomes - metabolism | Chromatin Assembly and Disassembly - genetics | DNA - metabolism | Chromatin Assembly and Disassembly - physiology | Chromatin | Genetic aspects | Research | Analysis | DNA | Adenosine triphosphatase | Translocation | Modules | Editing | Sliding | Translocase | Epitopes | Remodeling | Motor task performance | Chromatin remodeling | Proteins | ATP | Assembly | Deoxyribonucleic acid--DNA | Ejection
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3. Full Text Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host
by Timp, Winston and Feinberg, Andrew P
Nature Reviews Cancer, ISSN 1474-175X, 07/2013, Volume 13, Issue 7, pp. 497 - 510
Although at the genetic level cancer is caused by diverse mutations, epigenetic modifications are characteristic of all cancers, from apparently normal... 
PLURIPOTENT STEM-CELLS | CHROMATIN REMODELING GENES | DNA METHYLATION | HUMAN-COLON | ONCOLOGY | PROMOTER METHYLATION | COLORECTAL-CANCER | CPG ISLAND | HISTONE MODIFICATIONS | SOMATIC MUTATIONS | INACTIVATING MUTATIONS | Epigenesis, Genetic - physiology | Neoplasms - therapy | Neoplasms - genetics | Humans | Heterochromatin - physiology | Neoplasms - pathology | Chromatin Assembly and Disassembly - physiology | Epigenetic inheritance | Genetic aspects | Research | Cancer
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4. Full Text RNA-mediated epigenetic regulation of gene expression
by Holoch, Daniel and Moazed, Danesh
Nature Reviews Genetics, ISSN 1471-0056, 01/2015, Volume 16, Issue 2, pp. 71 - 84
Diverse classes of RNA, ranging from small to long non-coding RNAs, have emerged as key regulators of gene expression, genome stability and defence against... 
DIRECTED DNA METHYLATION | DOUBLE-STRANDED-RNA | FISSION YEAST | CAENORHABDITIS-ELEGANS | LONG NONCODING RNAS | GENETICS & HEREDITY | MEIOTIC MESSENGER-RNAS | FACULTATIVE HETEROCHROMATIN FORMATION | INACTIVE X-CHROMOSOME | HISTONE H3 METHYLATION | C. ELEGANS | Yeasts | Arabidopsis | Gene Expression Regulation - genetics | Gene Silencing | Heterochromatin - physiology | RNA - genetics | DNA Methylation | RNA Interference | Epigenesis, Genetic - genetics | Models, Biological | Chromatin Assembly and Disassembly - physiology | RNA - metabolism | RNA, Small Interfering - metabolism | Genetic research | Epigenetic inheritance | Research | RNA | Gene expression | Properties
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5. Full Text Inducible gene expression: diverse regulatory mechanisms
by Weake, Vikki M and Workman, Jerry L
Nature Reviews Genetics, ISSN 1471-0056, 06/2010, Volume 11, Issue 6, pp. 426 - 437
The rapid activation of gene expression in response to stimuli occurs largely through the regulation of RNA polymerase II-dependent transcription. In this... 
RNA-POLYMERASE-II | TRANSCRIPTIONAL ACTIVATION | H2B UBIQUITYLATION | HEAT-SHOCK FACTOR | DROSOPHILA-MELANOGASTER | HISTONE ACETYLTRANSFERASE COMPLEXES | EMBRYONIC STEM-CELLS | IN-VIVO | GENETICS & HEREDITY | MAP KINASE HOG1 | SACCHAROMYCES-CEREVISIAE | Phosphotransferases - metabolism | Transcription Factors - physiology | Humans | Chromatin Assembly and Disassembly - genetics | Signal Transduction - genetics | Gene Regulatory Networks - physiology | Transcription Factors - metabolism | Transcription, Genetic - physiology | Animals | Models, Biological | Transcriptional Activation - physiology | Transcription, Genetic - genetics | Phosphotransferases - physiology | Chromatin Assembly and Disassembly - physiology | Physiological aspects | Promoters (Genetics) | Research | Gene expression | RNA polymerases
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6. Full Text Relationship between nucleosome positioning and DNA methylation
by Feng, Suhua and Casero, David and Chodavarapu, Ramakrishna K and Kuo, Frank and Bernatavichute, Yana V and Kim, Jin and Stroud, Hume and Bernal, Maria and Clark, Amander T and Krämer, Ute and Jacobsen, Steven E and Merchant, Sabeeha S and Zhang, Xiaoyu and Pellegrini, Matteo and Yu, Yanchun and Hetzel, Jonathan A and Huijser, Peter and Chen, Pao-Yang and Cokus, Shawn J
Nature, ISSN 0028-0836, 07/2010, Volume 466, Issue 7304, pp. 388 - 392
Nucleosomes compact and regulate access to DNA in the nucleus, and are composed of approximately 147 bases of DNA wrapped around a histone octamer. Here we... 
ORGANIZATION | ANIMALS | PARTICLE | MULTIDISCIPLINARY SCIENCES | RESOLUTION | SEQUENCE | PLANTS | H2A.Z | MARKS | GENOME | REVEALS | Arabidopsis - enzymology | Genome, Plant - genetics | Humans | Nucleosomes - metabolism | Chromatin Assembly and Disassembly - genetics | Exons - genetics | Nucleosomes - genetics | DNA Methylation - genetics | DNA Polymerase II - metabolism | DNA, Plant - metabolism | Sequence Analysis, DNA | Arabidopsis - metabolism | Arabidopsis - genetics | DNA Polymerase II - analysis | Chromatin Immunoprecipitation | Genes, Plant - genetics | Micrococcal Nuclease - metabolism | DNA Methylation - physiology | DNA, Plant - genetics | Chromatin Assembly and Disassembly - physiology | DNA methylation | Genetics | Chromosomes | Deoxyribonucleic acid--DNA | Enrichment | Pol II | Deoxyribonucleic acid | Histones | Genomes | Boundaries | Methylation | RNA polymerase II
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7. Full Text Non-histone protein methylation as a regulator of cellular signalling and function
by Biggar, Kyle K and Li, Shawn S.-C
Nature Reviews Molecular Cell Biology, ISSN 1471-0072, 12/2014, Volume 16, Issue 1, pp. 5 - 17
Methylation of Lys and Arg residues on non-histone proteins has emerged as a prevalent post-translational modification and as an important regulator of... 
53BP1 RECRUITMENT | STRUCTURAL BASIS | PHOSPHORYLATION | DNA-DAMAGE RESPONSE | LYSINE METHYLATION | HIPPO PATHWAY | ARGININE METHYLATION | P53 ACTIVITY | BINDING | HISTONE METHYLTRANSFERASE | CELL BIOLOGY | MAP Kinase Signaling System - physiology | Humans | DNA Repair - physiology | Protein Biosynthesis - physiology | Protein-Serine-Threonine Kinases - genetics | STAT Transcription Factors - metabolism | Wnt Signaling Pathway - physiology | Extracellular Signal-Regulated MAP Kinases - metabolism | Wnt Proteins - metabolism | Extracellular Signal-Regulated MAP Kinases - genetics | STAT Transcription Factors - genetics | Transcription, Genetic - physiology | Animals | Wnt Proteins - genetics | Methylation | Protein-Serine-Threonine Kinases - metabolism | Chromatin Assembly and Disassembly - physiology | Genetic research | Cellular signal transduction | Genetic aspects | Research | Gene expression | Observations | Genetic translation
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