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Nature Genetics, ISSN 1061-4036, 04/2008, Volume 40, Issue 4, pp. 476 - 483
A major obstacle to creating precisely expressed transgenes lies in the epigenetic effects of the host chromatin that surrounds them. Here we present a... 
RNA INTERFERENCE | TRANSFORMATION | PHI-C31 INTEGRASE | PROTEIN | WHITE GENE | DROSOPHILA-MELANOGASTER | TRANSPOSABLE ELEMENT | GENETICS & HEREDITY | GENE-EXPRESSION | CHROMOSOMAL POSITION | REGULATORY ELEMENTS | Transgenes - physiology | Cytoskeletal Proteins - genetics | Receptors, Notch - metabolism | Molecular Sequence Data | Receptors, Notch - genetics | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Drosophila melanogaster - metabolism | Tissue Distribution | Retroviridae - genetics | Recombination, Genetic | Chromatin - physiology | Cytoskeletal Proteins - metabolism | Female | Insulator Elements - genetics | Myogenic Regulatory Factors - genetics | Animals, Genetically Modified | Larva - metabolism | Gene Expression Regulation | Genome, Insect - genetics | Myogenic Regulatory Factors - metabolism | HSP70 Heat-Shock Proteins - genetics | Saccharomyces cerevisiae Proteins - genetics | Wings, Animal - physiology | HSP70 Heat-Shock Proteins - metabolism | Phenotype | Animals | Plasmids | Saccharomyces cerevisiae Proteins - metabolism | Drosophila melanogaster - growth & development | Drosophila Proteins - genetics | Attachment Sites, Microbiological - genetics | Physiological aspects | Epigenetic inheritance | Genetic aspects | Retroviruses | Research | Gene expression | Chromatin | Insects | Transgenic animals | Genomics | Research methodology | Index Medicus
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 08/2017, Volume 101, Issue 2, pp. 206 - 217
Journal Article
Science, ISSN 0036-8075, 06/2015, Volume 348, Issue 6242, pp. 1481 - 1485
Forward genetic screens in Drosophila melanogaster for modifiers of position-effect variegation have revealed the basis of much of our understanding of... 
CHROMOSOMAL-PROTEIN | SITE | GENE | HISTONE H3 | DROSOPHILA-MELANOGASTER | MULTIDISCIPLINARY SCIENCES | HETEROCHROMATIN | LYSINE 9 | BINDING | Physiological aspects | Epigenetic inheritance | Gene silencing | Research | Drosophila | Epigenetics | Enzymes | Heterochromatin | Cellular biology | Deoxyribonucleic acid--DNA | Proteins | Genes | Histones | Genetics | Fish | Screens | Loci
Journal Article
Journal Article
Current protocols in human genetics, 04/2018, Volume 97, Issue 1
Balanced and apparently balanced chromosome abnormalities (BCAs) have long been known to generate disease through position effects, either by altering local... 
chromosome abnormality | human genetics | cytogenetics | position effects | Computational Biology - methods | Genetic Predisposition to Disease | Phenotype | Gene Rearrangement | Humans | Gene Expression Regulation | Chromosome Mapping | Chromosomes, Human | Genome, Human | Chromosomal Position Effects | Chromosome Disorders - genetics
Journal Article
Clinical Genetics, ISSN 0009-9163, 10/2017, Volume 92, Issue 4, pp. 415 - 422
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2018, Volume 13, Issue 10, pp. e0205298 - e0205298
The majority of apparently balanced translocation (ABT) carriers are phenotypically normal. However, several mechanisms were proposed to underlie phenotypes in... 
INTELLECTUAL DISABILITY | INACTIVATION | INNER-EAR | UPSTREAM | MULTIDISCIPLINARY SCIENCES | DEAFNESS | GENERATION | EXPRESSION | CHROMOSOMAL REARRANGEMENTS | PRENATAL-DIAGNOSIS | POU3F4 | Hearing Loss - diagnosis | Translocation, Genetic | Chromosome Breakpoints | Humans | NFI Transcription Factors - genetics | Intellectual Disability - genetics | POU Domain Factors - genetics | POU Domain Factors - deficiency | Language Development Disorders - diagnosis | Base Sequence | Facies | Female | Language Development Disorders - physiopathology | NFI Transcription Factors - deficiency | Gene Expression | Hearing Loss - physiopathology | Language Development Disorders - genetics | Whole Genome Sequencing | Hearing Loss - genetics | Intellectual Disability - physiopathology | Phenotype | Intellectual Disability - diagnosis | SOXD Transcription Factors - deficiency | SOXD Transcription Factors - genetics | Karyotype | Deafness | Genetic aspects | Research | Nucleotide sequencing | Mental retardation | DNA sequencing | Genes | Genomics | Pons | Transcription factors | Lung | Bioethics | Nervous system | Genomes | Gene deletion | Inactivation | Gene sequencing | Complexity | Genotype & phenotype | Clonal deletion | Gene disruption | Deletion | Translocation | Breakpoints | Phenotypes | Deactivation | Patients | Hearing loss | Carriers | Medicine | Neurology | Molecular modelling | Cytogenetics | Speech | Genetic engineering | Disruption | Index Medicus
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 02/2010, Volume 38, Issue 11, pp. 3582 - 3594
Journal Article