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Variant of transcription factor 7-like 2 ( TCF7L2 ) gene confers risk of type 2 diabetes
Nature genetics, ISSN 1061-4036, 03/2006, Volume 38, Issue 3, pp. 320 - 323
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Diabetes. Impaired glucose tolerance | Biological and medical sciences | Endocrinopathies | Etiopathogenesis. Screening. Investigations. Target tissue resistance | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Endocrine pancreas. Apud cells (diseases) | Genetic Predisposition to Disease | Introns | Diabetes Mellitus, Type 2 - genetics | Gene Frequency | Humans | Molecular Sequence Data | Reference Values | Chromosome Mapping | Transcription Factor 7-Like 2 Protein | Denmark | TCF Transcription Factors - genetics | Chromosomes, Human, Pair 10 | Genetic Carrier Screening | Microsatellite Repeats | Cohort Studies | Type 2 diabetes | Genetic variation | Physiological aspects | Causes of | Genetic aspects | DNA binding proteins | Research | Health aspects | Genotype & phenotype | Population | Diabetes | Index Medicus
Journal Article
The Lancet (British edition), ISSN 0140-6736, 2009, Volume 373, Issue 9679, pp. 1974 - 1986
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Neurology | Biological and medical sciences | General aspects | Medical sciences | Tumors of the nervous system. Phacomatoses | Peripheral Nervous System Diseases - etiology | Gene Frequency - genetics | Neurofibromin 2 - genetics | Genetic Testing | Molecular Biology | Cataract - etiology | Neurofibromatosis 2 - diagnosis | Humans | Penetrance | Survival Rate | Neurofibromatosis 2 - genetics | Neurofibromatosis 2 - therapy | Mutation - genetics | Genes, Neurofibromatosis 2 | Disease Progression | Nervous System Neoplasms - etiology | Chromosomes, Human, Pair 22 - genetics | Neurofibromatosis 2 - epidemiology | Patient Care Team - organization & administration | Pedigree | Skin Neoplasms - etiology | Care and treatment | Gene mutations | Neurofibromatosis | Physiological aspects | Tumor suppressor genes | Genetic aspects | Research | Health aspects | Risk factors | Membranes | Protein folding | Mortality | Genetics | Kinases | Molecular biology | Neurological disorders | Cell adhesion & migration | Index Medicus | Abridged Index Medicus
Journal Article
The New England journal of medicine, ISSN 0028-4793, 11/2013, Volume 369, Issue 19, pp. 1783 - 1796
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Hematologic and hematopoietic diseases | Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis | Biological and medical sciences | General aspects | Medical sciences | Thrombosis - chemically induced | Humans | Imidazoles - adverse effects | Middle Aged | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy | Male | Thrombocytopenia - chemically induced | Protein Kinase Inhibitors - adverse effects | Young Adult | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Protein Kinase Inhibitors - therapeutic use | Adolescent | Aged, 80 and over | Adult | Female | Aged | Imidazoles - therapeutic use | Pyridazines - adverse effects | Pyridazines - therapeutic use | Clinical trials | Research | Drug therapy | Leukemia | Tyrosine | Thrombocytopenia | BCR protein | Acute lymphatic leukemia | Threonine | Myeloid leukemia | Abl protein | Chronic myeloid leukemia | Lymphatic leukemia | Kinases | Patients | Philadelphia chromosome | Side effects | Pain | Skin | Mutation | Fusion protein | Protein-tyrosine kinase | Isoleucine | Index Medicus | Abridged Index Medicus
Journal Article
Diabetes (New York, N.Y.), ISSN 0012-1797, 02/2007, Volume 56, Issue 2, pp. 389 - 393
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Biological and medical sciences | Endocrinopathies | Etiopathogenesis. Screening. Investigations. Target tissue resistance | Diabetes. Impaired glucose tolerance | Medical sciences | Endocrine pancreas. Apud cells (diseases) | Haplotypes | Exons | Introns | Diabetes Mellitus, Type 2 - genetics | Humans | Transcription Factor 7-Like 2 Protein | Linkage Disequilibrium | Diabetes Mellitus, Type 2 - ethnology | Mexican Americans - genetics | Age of Onset | Alleles | Polymorphism, Single Nucleotide | Chromosomes, Human, Pair 10 - genetics | TCF Transcription Factors - genetics | Type 2 diabetes | Mexican Americans | Care and treatment | Analysis | Genetic aspects | Health aspects | Index Medicus | Abridged Index Medicus
Journal Article
International journal of hematology, ISSN 0925-5710, 2/2014, Volume 99, Issue 2, pp. 202 - 207
Medicine & Public Health | Hematology | Myeloid leukemia | inv(p23q13) | RANBP2 – ALK fusion gene | Oncology | Anti-ALK immunohistochemistry | RANBP2-ALK fusion gene | Life Sciences & Biomedicine | Science & Technology | Hematologic and hematopoietic diseases | Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis | Biological and medical sciences | Medical sciences | Leukemia, Myelomonocytic, Chronic - diagnosis | Oncogene Proteins, Fusion - metabolism | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Molecular Chaperones - metabolism | Cytarabine - therapeutic use | Humans | Leukemia, Myelomonocytic, Chronic - genetics | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Chromosome Inversion | Leukemia, Myelomonocytic, Chronic - drug therapy | Leukemia, Myelomonocytic, Chronic - metabolism | Chromosomes, Human, Pair 2 | Nuclear Pore Complex Proteins - genetics | Female | Daunorubicin - administration & dosage | Azacitidine - administration & dosage | Daunorubicin - therapeutic use | Diagnosis, Differential | Nuclear Pore Complex Proteins - metabolism | Molecular Chaperones - genetics | Treatment Outcome | Receptor Protein-Tyrosine Kinases - metabolism | Cytarabine - administration & dosage | Leukemia, Myeloid, Acute - diagnosis | Receptor Protein-Tyrosine Kinases - genetics | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Oncogene Proteins, Fusion - genetics | Aged | Azacitidine - therapeutic use | Immunohistochemistry | Anthracyclines | RNA | Genes | Fluorescence | Myelocytic leukemia | Genetic research | DNA polymerases | Genetic aspects | Nonlymphoid leukemia | Chemical properties | Protein binding | Cancer | Index Medicus
Journal Article
Human pathology, ISSN 0046-8177, 2013, Volume 44, Issue 9, pp. 1817 - 1826
Pathology | t(14;18) translocation | BCL2-negative follicular lymphoma | BCL2 mutations | BCL2 E17 and SP66 antibodies | Life Sciences & Biomedicine | Science & Technology | Lymphoma, Follicular - metabolism | Translocation, Genetic | Lymph Nodes - pathology | Proto-Oncogene Proteins c-bcl-2 - immunology | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Lymphoma, Follicular - diagnosis | Male | Proto-Oncogene Proteins c-bcl-2 - metabolism | Lymphoma, Follicular - genetics | Neoplasm Grading | DNA Mutational Analysis | Aged, 80 and over | Adult | Female | Clone Cells | DNA, Neoplasm - analysis | Lymph Nodes - metabolism | In Situ Hybridization, Fluorescence | Point Mutation | Chromosomes, Human, Pair 18 | Chromosomes, Human, Pair 14 | Aged | Proto-Oncogene Proteins c-bcl-2 - genetics | Immunohistochemistry | Fluorescence | Immunoglobulin E | Lymphomas | Analysis | Antigenic determinants | Proteins | Mutation | Cloning | Deoxyribonucleic acid--DNA | Index Medicus
Journal Article
British journal of pharmacology, ISSN 0007-1188, 04/2017, Volume 174, Issue 8, pp. 641 - 656
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Neurons - pathology | Vanadium Compounds - chemistry | Humans | Structure-Activity Relationship | Enzyme Inhibitors - chemical synthesis | Oxygen - metabolism | Dose-Response Relationship, Drug | Neuroprotective Agents - pharmacology | Enzyme Inhibitors - chemistry | Vanadium Compounds - pharmacology | Cell Death - drug effects | Tumor Cells, Cultured | Neurons - drug effects | Disease Models, Animal | Neuroprotective Agents - chemistry | Enzyme Inhibitors - pharmacology | PTEN Phosphohydrolase - metabolism | Rats | Rats, Sprague-Dawley | Neuroprotective Agents - chemical synthesis | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Brain Ischemia - drug therapy | Brain Ischemia - pathology | Glucose - metabolism | Vanadium Compounds - chemical synthesis | Mitogen-Activated Protein Kinase 1 - metabolism | Stroke (Disease) | Phosphatases | Neurons | Cell death | Occlusion | Neuroprotection