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1. Full Text Variant of transcription factor 7-like 2 ( TCF7L2 ) gene confers risk of type 2 diabetes
by Jonsdottir, Thorbjorg and Walters, G Bragi and Saemundsdottir, Jona and Thorsteinsdottir, Unnur and Bagger, Yu and Wilensky, Robert L and Sainz, Jesus and Styrkarsdottir, Unnur and Benediktsson, Rafn and Gylfason, Arnaldur and Palsdottir, Ebba and Gulcher, Jeffrey R and Grant, Struan F A and Gudmundsdottir, Thorunn and Kong, Augustine and Gudnason, Vilmundur and Helgadottir, Anna and Rader, Daniel J and Sigurdsson, Gunnar and Reilly, Muredach P and Manolescu, Andrei and Stefansson, Kari and Emilsson, Valur and Stefansson, Hreinn and Reynisdottir, Inga and Magnusson, Kristinn P and Christiansen, Claus and Thorleifsson, Gudmar and Helgason, Agnar
Nature Genetics, ISSN 1061-4036, 03/2006, Volume 38, Issue 3, pp. 320 - 323
We have previously reported suggestive linkage of type 2 diabetes mellitus to chromosome 10q. We genotyped 228 microsatellite markers in Icelandic individuals... 
TCF-4 | MODELS | DISEASE | GENETICS & HEREDITY | POLYMORPHISM | MELLITUS | BETA-CATENIN | LINKAGE | ONSET | Genetic Predisposition to Disease | Introns | Diabetes Mellitus, Type 2 - genetics | Gene Frequency | Humans | Molecular Sequence Data | Reference Values | Chromosome Mapping | Transcription Factor 7-Like 2 Protein | Denmark | TCF Transcription Factors - genetics | Chromosomes, Human, Pair 10 | Genetic Carrier Screening | Microsatellite Repeats | Cohort Studies | Type 2 diabetes | Genetic variation | Physiological aspects | Causes of | Genetic aspects | DNA binding proteins | Research | Health aspects | Genotype & phenotype | Population | Diabetes
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2. Full Text Haplotypes of Transcription Factor 7–Like 2 (TCF7L2) Gene and Its Upstream Region Are Associated With Type 2 Diabetes and Age of Onset in Mexican Americans
by Donna M. Lehman and Kelly J. Hunt and Robin J. Leach and Jeanette Hamlington and Rector Arya and Hanna E. Abboud and Ravindranath Duggirala and John Blangero and Harald H.H. Göring and Michael P. Stern
Diabetes, ISSN 0012-1797, 02/2007, Volume 56, Issue 2, pp. 389 - 393
Haplotypes of Transcription Factor 7–Like 2 ( TCF7L2 ) Gene and Its Upstream Region Are Associated With Type 2 Diabetes and Age of Onset in Mexican Americans... 
LOCATION | POLYMORPHISMS | MODELS | MEASURED GENOTYPE | TRAIT LINKAGE ANALYSIS | ENDOCRINOLOGY & METABOLISM | Haplotypes | Exons | Introns | Diabetes Mellitus, Type 2 - genetics | Humans | Transcription Factor 7-Like 2 Protein | Linkage Disequilibrium | Diabetes Mellitus, Type 2 - ethnology | Mexican Americans - genetics | Age of Onset | Alleles | Polymorphism, Single Nucleotide | Chromosomes, Human, Pair 10 - genetics | TCF Transcription Factors - genetics | Type 2 diabetes | Mexican Americans | Care and treatment | Analysis | Genetic aspects | Health aspects
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3. Full Text Neurofibromatosis type 2
by Asthagiri, Ashok R, Dr and Parry, Dilys M, PhD and Butman, John A, MD and Kim, H Jeffrey, MD and Tsilou, Ekaterini T, MD and Zhuang, Zhengping, Prof and Lonser, Russell R, Prof
Lancet, The, ISSN 0140-6736, 2009, Volume 373, Issue 9679, pp. 1974 - 1986
Summary Neurofibromatosis type 2 is an autosomal-dominant multiple neoplasia syndrome that results from mutations in the NF2 tumour suppressor gene located on... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | NF2 TUMOR-SUPPRESSOR | GENOTYPE-PHENOTYPE CORRELATIONS | STEREOTACTIC RADIOSURGERY | VESTIBULAR SCHWANNOMA GROWTH | NERVOUS-SYSTEM TUMORS | TERM-FOLLOW-UP | SPINAL-CORD EPENDYMOMAS | OF-THE-LITERATURE | NATURAL-HISTORY | BILATERAL ACOUSTIC NEUROFIBROMATOSIS | Peripheral Nervous System Diseases - etiology | Gene Frequency - genetics | Neurofibromin 2 - genetics | Genetic Testing | Molecular Biology | Cataract - etiology | Neurofibromatosis 2 - diagnosis | Humans | Penetrance | Survival Rate | Neurofibromatosis 2 - genetics | Neurofibromatosis 2 - therapy | Mutation - genetics | Genes, Neurofibromatosis 2 | Disease Progression | Nervous System Neoplasms - etiology | Chromosomes, Human, Pair 22 - genetics | Neurofibromatosis 2 - epidemiology | Patient Care Team - organization & administration | Pedigree | Skin Neoplasms - etiology | Care and treatment | Gene mutations | Neurofibromatosis | Physiological aspects | Tumor suppressor genes | Genetic aspects | Research | Health aspects | Risk factors | Membranes | Protein folding | Mortality | Genetics | Kinases | Molecular biology | Neurological disorders | Cell adhesion & migration
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4. Full Text Methyl-CpG-binding protein 2 (MECP2) mutation type is associated with disease severity in rett syndrome
by Cuddapah, Vishnu Anand and Pillai, Rajesh B and Shekar, Kiran V and Lane, Jane B and Motil, Kathleen J and Skinner, Steven A and Tarquinio, Daniel Charles and Glaze, Daniel G and McGwin, Gerald and Kaufmann, Walter E and Percy, Alan K and Neul, Jeffrey L and Olsen, Michelle L
Journal of Medical Genetics, ISSN 0022-2593, 2014, Volume 51, Issue 3, pp. 152 - 158
Background Rett syndrome (RTT), a neurodevelopmental disorder that primarily affects girls, is characterised by a period of apparently normal development until... 
GENOTYPE-PHENOTYPE RELATIONSHIPS | X-CHROMOSOME INACTIVATION | DATABASE | GENETICS & HEREDITY | Severity of Illness Index | Rett Syndrome - epidemiology | Genetic Association Studies | Rett Syndrome - classification | Humans | Child, Preschool | Infant | Male | Mutation - genetics | Methyl-CpG-Binding Protein 2 - genetics | Rett Syndrome - physiopathology | Young Adult | Adolescent | Adult | Female | Rett Syndrome - genetics | Child | Influence | Mutation (Biology) | Risk factors | Rett syndrome | Studies | Proteins | Congenital diseases | Mutation | Localization | Age | Deoxyribonucleic acid--DNA | MeCP2 | RTT | genotype-phenotype
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5. Introductory statistical genetics for plant breeding
: part 2 of 2
by Eeuwijk, Fred van
2016, Statistical genetics
Data Interpretation, Statistical | methods | Plant genetics | Genotype | Chromosome Mapping | Statistical methods | Models, Statistical | Genetic Techniques | Gene-Environment Interaction | Statistics | Biometry | Genotype-environment interaction | Genetic markers | Phenotype | Plant breeding | statistics & numerical data | Gene mapping | Quantitative Trait Loci | Cohort Studies
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6. Genetic epidemiology of obesity
: part 2 of 2
by Loos, Ruth
2015, Obesity : science, medicine and society
Body Mass Index | Obesity | Genome-Wide Association Study | Genetics, Medical | genetics | Molecular Epidemiology | Medical genetics | Chromosome Mapping | Genetic aspects | Epidemiology
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7. Full Text Targeting ninjurin 2 by miR-764 regulates hydrogen peroxide (H2O2)-induced neuronal cell death
by Jing, Ding and Yinzhu, Li and Jinjing, Pang and Lishuang, Liang and Guozhuan, Zhang
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 11/2018, Volume 505, Issue 4, pp. 1180 - 1188
Ninjurin 2 (NINJ2) is a novel adhesion molecule expressed in neurons and glial cells. The current study determined if specific ( ) can regulate expression in... 
Neuronal cells | Hydrogen peroxide | microRNA-764 | Ninjurin 2 | OXIDATIVE STRESS | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | NONCODING RNA | IMPACT | CHROMOSOME 12P13 | POLYMORPHISMS | BIOPHYSICS | NINJ2 | MITOCHONDRIAL DYSFUNCTION | ISCHEMIC-STROKE | ASSOCIATION | Biochemistry | MicroRNA | Neurons | Cell death | Analysis
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8. Full Text ETHYLENE-INSENSITIVE5 Encodes a 5'→3' Exoribonuclease Required for Regulation of the EIN3-Targeting F-box Proteins EBF1/2
by Gabriela Olmedo and Hongwei Guo and Brian D. Gregory and Saeid D. Nourizadeh and Laura Aguilar-Henonin and Hongjiang Li and Fengying An and Plinio Guzman and Joseph R. Ecker
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2006, Volume 103, Issue 36, pp. 13286 - 13293
Ethylene is a gaseous plant growth regulator that controls a multitude of developmental and stress responses. Recently, the levels of Arabidopsis EIN3 protein,... 
Signal transduction | Phenotypes | Messenger RNA | RNA | Alleles | Gene expression regulation | Plants | Gene expression | Genetic mutation | Seedlings | Arabidopsis | Growth regulation | OF-FUNCTION MUTATION | MUTANT | ARABIDOPSIS-THALIANA | signal transduction | ETHYLENE SIGNAL-TRANSDUCTION | MULTIDISCIPLINARY SCIENCES | growth regulation | GENOME | MESSENGER-RNAS | GENE | RESPONSE PATHWAY | GAS | EXPRESSION | Exoribonucleases - genetics | Arabidopsis - growth & development | Genes, Plant | Exoribonucleases - chemistry | Molecular Sequence Data | Seedlings - genetics | Phylogeny | Genetic Complementation Test | Seedlings - growth & development | Ethylenes - metabolism | Arabidopsis Proteins - metabolism | Plant Proteins - chemistry | Plant Proteins - metabolism | Arabidopsis Proteins - genetics | F-Box Proteins - metabolism | Physical Chromosome Mapping | Chromosomes, Plant | Arabidopsis - metabolism | Nuclear Proteins | Arabidopsis - genetics | Plant Proteins - genetics | Feedback, Physiological | Gene Expression Regulation, Plant - physiology | Transcription Factors | Mutation | F-Box Proteins - genetics | Exoribonucleases - metabolism | Proteins | Research | Ethylene | Biological Sciences
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9. The future of CNVs
: sequence based resolution and links to human disease, (part 2 of 2)
by Eichler, Evan
2017, Copy number variation : expanding the repertoire of genetic alterations in studies of natural variation and disease
Sequence Deletion | Nucleotide sequence | Genomics | methods | Molecular Sequence Data | Gene Dosage | Sequence Inversion | Genotyping Techniques | Chromosome Inversion | Sequence Analysis, DNA | DNA Copy Number Variations | Genetic Variation | Genetics, Medical | genetics | Variation (Biology) | Chromosomes, Human, Pair 17 | Medical genetics | Biomarkers | High-Throughput Nucleotide Sequencing | Genome, Human | Human genetics | trends | Biochemical markers
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10. Full Text A Phase 2 Trial of Ponatinib in Philadelphia Chromosome–Positive Leukemias
by Cortes, J.E and Kim, D.-W and Pinilla-Ibarz, J and le Coutre, P and Paquette, R and Chuah, C and Nicolini, F.E and Apperley, J.F and Khoury, H.J and Talpaz, M and DiPersio, J and DeAngelo, D.J and Abruzzese, E and Rea, D and Baccarani, M and Müller, M.C and Gambacorti-Passerini, C and Wong, S and Lustgarten, S and Rivera, V.M and Clackson, T and Turner, C.D and Haluska, F.G and Guilhot, F and Deininger, M.W and Hochhaus, A and Hughes, T and Goldman, J.M and Shah, N.P and Kantarjian, H and PACE Investigators
The New England Journal of Medicine, ISSN 0028-4793, 11/2013, Volume 369, Issue 19, pp. 1783 - 1796
Several tyrosine kinase inhibitors have activity in Ph-positive chronic and acute leukemia, but resistant disease and unacceptable side effects may limit... 
CHRONIC MYELOGENOUS LEUKEMIA | MEDICINE, GENERAL & INTERNAL | OCCLUSIVE DISEASE | INHIBITOR THERAPY | DIAGNOSED CHRONIC-PHASE | FOLLOW-UP | ABL KINASE DOMAIN | MUTATIONS | IMATINIB RESISTANCE | NILOTINIB | CHRONIC MYELOID-LEUKEMIA | Thrombosis - chemically induced | Humans | Imidazoles - adverse effects | Middle Aged | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy | Male | Thrombocytopenia - chemically induced | Protein Kinase Inhibitors - adverse effects | Young Adult | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Protein Kinase Inhibitors - therapeutic use | Adolescent | Aged, 80 and over | Adult | Female | Aged | Imidazoles - therapeutic use | Pyridazines - adverse effects | Pyridazines - therapeutic use | Clinical trials | Research | Drug therapy | Leukemia | Tyrosine | Thrombocytopenia | BCR protein | Acute lymphatic leukemia | Threonine | Myeloid leukemia | Abl protein | Chronic myeloid leukemia | Lymphatic leukemia | Kinases | Patients | Philadelphia chromosome | Side effects | Pain | Skin | Mutation | Fusion protein | Protein-tyrosine kinase | Isoleucine
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11. Full Text Genomewide Search for Type 2 Diabetes–Susceptibility Genes in French Whites: Evidence for a Novel Susceptibility Locus for Early-Onset Diabetes on Chromosome 3q27-qter and Independent Replication of a Type 2–Diabetes Locus on Chromosome 1q21–q24
by Vionnet, Nathalie and Hani, El Habib and Dupont, Sophie and Gallina, Philippe and Gallina, Sophie and Francke, Stephan and Dotte, Sébastien and De Matos, Frédérique and Durand, Emmanuelle and Leprêtre, Frédéric and Lecoeur, Cécile and Zekiri, Lirije and Dina, Christian and Froguel, Philippe
The American Journal of Human Genetics, ISSN 0002-9297, 2000, Volume 67, Issue 6, pp. 1470 - 1480
Despite recent advances in the molecular genetics of type 2 diabetes, the majority of susceptibility genes in humans remain to be identified. We therefore... 
AUTOSOMAL GENOMIC SCAN | PIMA-INDIANS | SERUM LEPTIN LEVELS | AFFECTED SIB PAIRS | MEXICAN-AMERICANS | GENETICS & HEREDITY | QUANTITATIVE TRAIT LOCUS | WIDE SEARCH | HUMAN OBESITY | LINKAGE ANALYSIS | MELLITUS | European Continental Ancestry Group - genetics | France - epidemiology | Genetic Predisposition to Disease - genetics | Diabetes Mellitus, Type 2 - genetics | Humans | Middle Aged | Nuclear Family | Genotype | Male | Chromosome Mapping | Lod Score | Diabetes Mellitus, Type 2 - epidemiology | Phenotype | Matched-Pair Analysis | Age of Onset | DNA Replication - genetics | Female | Chromosomes, Human, Pair 1 - genetics | Genome, Human | Chromosomes, Human, Pair 3 - genetics | Type 2 diabetes | Genetic aspects | Research | Human genetics | Life Sciences
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