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Journal Article
Journal Article
Science, ISSN 0036-8075, 03/2017, Volume 355, Issue 6329, pp. eaaf4831 - eaaf4831
Journal Article
Science, ISSN 0036-8075, 03/2017, Volume 355, Issue 6329, pp. eaaf4791 - eaaf4791
Here, we report the successful design, construction, and characterization of a 770-kilobase synthetic yeast chromosome II (synII). Our study incorporates... 
REPLICATION | TRANSFER-RNA DECAY | CLONING | PATHWAY | MULTIDISCIPLINARY SCIENCES | GENES | EXPLORATION | DUPLICATION | SEQUENCING DATA | SACCHAROMYCES-CEREVISIAE | MYCOPLASMA-GENITALIUM GENOME | Chromosomes, Artificial, Yeast - chemistry | Chromosomes, Artificial, Yeast - physiology | Chromosome Segregation | Saccharomyces cerevisiae - genetics | Transcriptome | Glycerol | DNA Replication | Sequence Analysis, DNA | Chromosomes, Artificial, Yeast - genetics | Synthetic Biology | Genome, Fungal | Proteomics | Culture Media - chemistry | Saccharomyces cerevisiae - growth & development | Regulations | Profiling | Copy number | Homologous recombination | Assaying | Gene sequencing | Complexity | Design | Cellular communication | Temperature effects | Complementation | Computer networks | Chromosomes | Carbon sources | Deoxyribonucleic acid--DNA | Construction | Translation | tRNA | Meiosis | Gene expression | Replication | Anaphase | Metabolomics | Yeast | Genes | Gene regulation | Homology | Genomes | High temperature | Defects | Clonal deletion | Metaphase | Cell cycle | Deletion | Chromosome II | Evolution | Iterative methods | Integration | Osmolarity | Colonies | Debugging | Functional analysis | Ribonucleic acid--RNA | Biological activity | DNA biosynthesis | Phenotyping | Strategy | In vivo methods and tests | Index Medicus | Origins | Segregations | Glycerols
Journal Article
Science, ISSN 0036-8075, 03/2017, Volume 355, Issue 6329, pp. eaaf3981 - eaaf3981
Journal Article
by Xie, Ze-Xiong and Li, Bing-Zhi and Mitchell, Leslie A and Wu, Yi and Qi, Xin and Jin, Zhu and Jia, Bin and Wang, Xia and Zeng, Bo-Xuan and Liu, Hui-Min and Wu, Xiao-Le and Feng, Qi and Zhang, Wen-Zheng and Liu, Wei and Ding, Ming-Zhu and Li, Xia and Zhao, Guang-Rong and Qiao, Jian-Jun and Cheng, Jing-Sheng and Zhao, Meng and Kuang, Zheng and Wang, Xuya and Martin, J. Andrew and Stracquadanio, Giovanni and Yang, Kun and Bai, Xue and Zhao, Juan and Hu, Meng-Long and Lin, Qiu-Hui and Zhang, Wen-Qian and Shen, Ming-Hua and Chen, Si and Su, Wan and Wang, En-Xu and Guo, Rui and Zhai, Fang and Guo, Xue-Jiao and Du, Hao-Xing and Zhu, Jia-Qing and Song, Tian-Qing and Dai, Jun-Jun and Li, Fei-Fei and Jiang, Guo-Zhen and Han, Shi-Lei and Liu, Shi-Yang and Yu, Zhi-Chao and Yang, Xiao-Na and Chen, Ken and Hu, Cheng and Li, Da-Shuai and Jia, Nan and Liu, Yue and Wang, Lin-Ting and Wang, Su and Wei, Xiao-Tong and Fu, Mei-Qing and Qu, Lan-Meng and Xin, Si-Yu and Liu, Ting and Tian, Kai-Ren and Li, Xue-Nan and Zhang, Jin-Hua and Song, Li-Xiang and Liu, Jin-Gui and Lv, Jia-Fei and Xu, Hang and Tao, Ran and Wang, Yan and Zhang, Ting-Ting and Deng, Ye-Xuan and Wang, Yi-Ran and Li, Ting and Ye, Guang-Xin and Xu, Xiao-Ran and Xia, Zheng-Bao and Zhang, Wei and Yang, Shi-Lan and Liu, Yi-Lin and Ding, Wen-Qi and Liu, Zhen-Ning and Zhu, Jun-Qi and Liu, Ning-Zhi and Walker, Roy and Luo, Yisha and Wang, Yun and Shen, Yue and Yang, Huanming and Cai, Yizhi and Ma, Ping-Sheng and Zhang, Chun-Ting and Bader, Joel S and Boeke, Jef D and Yuan, Ying-Jin
Science, ISSN 0036-8075, 03/2017, Volume 355, Issue 6329, pp. eaaf4704 - eaaf4704
Journal Article
Molecular Cell, ISSN 1097-2765, 2011, Volume 44, Issue 6, pp. 978 - 988
Genome instability, a hallmark of cancer progression, is thought to arise through DNA double strand breaks (DSBs). Studies in yeast and mammalian cells have... 
GROSS CHROMOSOMAL REARRANGEMENTS | II TRANSCRIPTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENE-EXPRESSION | TRANSCRIPTION ELONGATION | TOPOISOMERASE-I | POLYMERASE-II | SACCHAROMYCES-CEREVISIAE | S-PHASE CHECKPOINT | MITOTIC RECOMBINATION | DNA-REPLICATION | CELL BIOLOGY | Nucleic Acid Hybridization | Ribonucleases - genetics | Histone Deacetylases - genetics | Saccharomyces cerevisiae - genetics | Repressor Proteins - genetics | Histone Deacetylases - metabolism | Saccharomyces cerevisiae Proteins - genetics | Ribonucleases - metabolism | Chromosomes, Artificial, Yeast - genetics | RNA - genetics | DNA - genetics | RNA - biosynthesis | Cell Cycle | Rad52 DNA Repair and Recombination Protein - metabolism | Chromosomes, Artificial, Yeast - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Saccharomyces cerevisiae - enzymology | Transcription, Genetic | Mutation | Genomic Instability - genetics | Repressor Proteins - metabolism | Ribonuclease H - genetics | Ribonuclease H - metabolism | RNA | Oncology, Experimental | Genomics | DNA | Genetic research | Genomes | Biosynthesis | Research | Ribonuclease | Cells | Cancer | Enzymes | Hybrids | Splicing | Transcription | DNA damage | Ribonuclease H | Mammalian cells | Gene silencing | RNA transport | Evolution | Elongation | Rad52 protein | RNA-DNA hybrids | RNase H | transcription | genome instability
Journal Article
Science, ISSN 0036-8075, 03/2017, Volume 355, Issue 6329, pp. eaaf4597 - eaaf4597
Journal Article
Journal Article
Science, ISSN 0036-8075, 03/2017, Volume 355, Issue 6329, pp. eaaf4706 - eaaf4706
Journal Article