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The American Journal of Human Genetics, ISSN 0002-9297, 05/2012, Volume 90, Issue 5, pp. 784 - 795
Psoriasis is a common, immune-mediated genetic disorder of the skin and is associated with arthritis in approximately 30% of cases. Previously, we localized... 
GENERALIZED PUSTULAR PSORIASIS | FAMILIAL PSORIASIS | GENE | PSORIASIS SUSCEPTIBILITY LOCI | GENETICS & HEREDITY | EPIDERMAL-KERATINOCYTES | 17Q | IDENTIFICATION | ARTHRITIS | NF-KAPPA-B | GENOME-WIDE ASSOCIATION | Haiti | Up-Regulation | Exons | Arthritis, Psoriatic - physiopathology | Humans | Child, Preschool | Molecular Sequence Data | NF-kappa B - metabolism | Gene Expression Profiling | Chemokine CCL20 | Genetic Loci | Chromosomes, Human, Pair 17 - genetics | CARD Signaling Adaptor Proteins - genetics | CARD Signaling Adaptor Proteins - metabolism | Cloning, Molecular | HEK293 Cells | Female | Membrane Proteins - metabolism | Amino Acid Sequence | Chromosomes, Human, Pair 17 - metabolism | Epidermis - metabolism | Genetic Predisposition to Disease | Membrane Proteins - genetics | Europe | Guanylate Cyclase - metabolism | Transcription Factors - genetics | Sequence Analysis, DNA | Arthritis, Psoriatic - genetics | Proteins - genetics | Transcription Factors - metabolism | Proteins - metabolism | NF-kappa B - genetics | Keratinocytes - metabolism | Pedigree | Taiwan | Guanylate Cyclase - genetics | Skin | Mutation | Genome, Human | Europeans | Gene mutations | Genetic susceptibility | Psoriasis | Genetic aspects | Research | Nucleotide sequencing | DNA sequencing | Diseases | Genomics | Medical genetics | Genes | Cell cycle | Families & family life | Genetics | Chromosomes | Index Medicus | Splicing | Susceptibility | Caspase | Keratinocytes | Epidermis | Arthritis | Inflammation | NF- Kappa B protein | CCL20 protein | Skin diseases | genomics | Age | Chemokines | Injuries | Interleukin 8
Journal Article
Blood, ISSN 0006-4971, 2009, Volume 113, Issue 16, pp. 3801 - 3808
Journal Article
by Rusu, Victor and Hoch, Eitan and Mercader, Josep M and Tenen, Danielle E and Gymrek, Melissa and Hartigan, Christina R and DeRan, Michael and von Grotthuss, Marcin and Fontanillas, Pierre and Spooner, Alexandra and Guzman, Gaelen and Deik, Amy A and Pierce, Kerry A and Dennis, Courtney and Clish, Clary B and Carr, Steven A and Wagner, Bridget K and Schenone, Monica and Ng, Maggie C.Y and Chen, Brian H and Chen, Guanjie and Chen, Wei-Min and Chen, Y-D Ida and Shriner, Daniel and Li, Jiang and Guo, Xiuqing and Liu, Jiankang and Liu, Yongmei and Liu, Simin and Bielinski, Suzette J and Yanek, Lisa R and Nalls, Michael A and Comeau, Mary E and Rasmussen-Torvik, Laura J and Jensen, Richard A and Evans, Michele K and Evans, Daniel S and Sun, Yan V and An, Ping and Patel, Sanjay R and Lu, Yingchang and Long, Jirong and Armstrong, Loren L and Wagenknecht, Lynne and Yang, Lingyao and Snively, Beverly M and Palmer, Nicholette D and Mudgal, Poorva and Langefeld, Carl D and Keene, Keith L and Freedman, Barry I and Mychaleckyj, Josyf C and Nayak, Uma and Raffel, Leslie J and Goodarzi, Mark O and Taylor, Herman A and Correa, Adolfo and Sims, Mario and Couper, David and Pankow, James S and Boerwinkle, Eric and Adeyemo, Adebowale and Doumatey, Ayo and Mathias, Rasika A and Vaidya, Dhananjay and Singleton, Andrew B and Zonderman, Alan B and Igo, Robert P and Sedor, John R and Kabagambe, Edmond K and Siscovick, David S and McKnight, Barbara and Rice, Kenneth and Hsueh, Wen-Chi and Zhao, Wei and Bielak, Lawrence F and Kraja, Aldi and Province, Michael A and Bottinger, Erwin P and Gottesman, Omri and Cai, Qiuyin and Zheng, Wei and Blot, William J and Lowe, William L and Pacheco, Jennifer A and Crawford, Dana C and Grundberg, Elin and Rich, Stephen S and Hayes, M. Geoffrey and Shu, Xiao-Ou and Loos, Ruth J.F and Borecki, Ingrid B and Peyser, Patricia A and Cummings, Steven R and Psaty, Bruce M and Fornage, Myriam and Iyengar, Sudha K and Becker, Diane M and Kao, W.H. Linda and Wilson, James G and ... and MEDIA Consortium and SIGMA T2D Consortium
Cell, ISSN 0092-8674, 06/2017, Volume 170, Issue 1, pp. 199 - 212.e20
Journal Article
Genome Research, ISSN 1088-9051, 08/2012, Volume 22, Issue 8, pp. 1437 - 1446
Journal Article
Journal of Proteome Research, ISSN 1535-3893, 01/2013, Volume 12, Issue 1, pp. 45 - 57
Journal Article
PLoS computational biology, ISSN 1553-7358, 12/2018, Volume 14, Issue 12, pp. e1006686 - e1006686
Journal Article
Blood, ISSN 0006-4971, 01/2010, Volume 115, Issue 2, pp. 326 - 330
Therapy-related acute promyelocytic leukemia (t-APL) with t(15; 17)(q22; q21) involving the PML and RARA genes is associated with exposure to agents targeting... 
BREAST-CANCER | APOPTOSIS | INTERNATIONAL WORKSHOP | DNA TOPOISOMERASE-II | CYCLOPHOSPHAMIDE | LEUKEMOGENESIS | SECONDARY | ACUTE MYELOID-LEUKEMIA | HEMATOLOGY | BREAKPOINT CLUSTER REGION | MYELODYSPLASTIC SYNDROMES | Humans | Middle Aged | Antibiotics, Antineoplastic - adverse effects | Epirubicin - administration & dosage | Translocation, Genetic - drug effects | Chromosomes, Human, Pair 17 - genetics | Receptors, Retinoic Acid - genetics | Breast Neoplasms - metabolism | Leukemia, Promyelocytic, Acute - metabolism | Neoplasms, Second Primary - chemically induced | Topoisomerase II Inhibitors | Tumor Suppressor Proteins - genetics | DNA Damage - genetics | Adult | Female | Neoplasms, Second Primary - genetics | Nuclear Proteins - genetics | DNA Damage - drug effects | Chromosomes, Human, Pair 17 - metabolism | DNA Topoisomerases, Type II - metabolism | Tumor Suppressor Proteins - metabolism | Chromosomes, Human, Pair 15 - metabolism | Introns - genetics | Nuclear Proteins - metabolism | Receptors, Retinoic Acid - metabolism | Transcription Factors - genetics | Chromosomes, Human, Pair 15 - genetics | Breast Neoplasms - drug therapy | Leukemia, Promyelocytic, Acute - chemically induced | Antibiotics, Antineoplastic - administration & dosage | Transcription Factors - metabolism | Neoplasms, Second Primary - metabolism | Breast Neoplasms - genetics | DNA Topoisomerases, Type II - genetics | Mitoxantrone - pharmacology | Leukemia, Promyelocytic, Acute - genetics | Quantitative Trait Loci | Retinoic Acid Receptor alpha | Promyelocytic Leukemia Protein | Epirubicin - adverse effects | Index Medicus | Abridged Index Medicus | Myeloid Neoplasia
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 4394 - 15
Heterozygous deletion of chromosome 17p (17p) is one of the most frequent genomic events in human cancers. Beyond the tumor suppressor TP53, the POLR2A gene... 
BREAST-CANCER | GENE ESSENTIALITY | POOR-PROGNOSIS | MULTIDISCIPLINARY SCIENCES | CRISPR-CAS9 SYSTEM | IN-VIVO | MONOCLONAL-ANTIBODY | AMANITA-PHALLOIDES | ALLELIC LOSS | CELL-GROWTH | ADVANCED COLORECTAL-CANCER | Immunohistochemistry | Chromosomes, Human, Pair 17 - metabolism | Immunoprecipitation | Sequence Deletion - physiology | Humans | Cell Survival - genetics | Apoptosis - genetics | Immunoblotting | Male | RNA Polymerase II - metabolism | Prostatic Neoplasms, Castration-Resistant - metabolism | Chromosomes, Human, Pair 17 - genetics | Prostatic Neoplasms, Castration-Resistant - genetics | Ubiquitin-Protein Ligases | Carrier Proteins - genetics | Transcription, Genetic - physiology | Carrier Proteins - metabolism | Cell Line, Tumor | RNA Polymerase II - genetics | Apoptosis - physiology | Transcription, Genetic - genetics | Cell Survival - physiology | Sequence Deletion - genetics | Ubiquitin | Transcription | p53 Protein | DNA-directed RNA polymerase | Metastases | Ubiquitination | Clonal deletion | Castration | Dependence | Deletion | Catalysis | Inhibition | Chromosome 17 | Ubiquitin-protein ligase | CRISPR | Therapeutic applications | Chromosome deletion | RNA polymerase | Amanitin | Polymerase | Ribonucleic acids | Tumor suppressor genes | Prostate cancer | Prostate | RNA polymerase II | Cancer | Index Medicus
Journal Article