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1. Full Text A genome-wide association study identifies novel risk loci for type 2 diabetes
by Meyre, David and Balding, David J and Rung, Johan and Polychronakos, Constantin and Vincent, Daniel and Hadjadj, Samy and Balkau, Beverley and Serre, David and Froguel, Philippe and Hudson, Thomas J and Posner, Barry I and Sladek, Robert and Rocheleau, Ghislain and Boutin, Philippe and Belisle, Alexandre and Prentki, Marc and Montpetit, Alexandre and Pshezhetsky, Alexey V and Shen, Lishuang and Dina, Christian and Heude, Barbara and Charpentier, Guillaume
Nature (London), ISSN 0028-0836, 02/2007, Volume 445, Issue 7130, pp. 881 - 885
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Biological and medical sciences | Endocrinopathies | Etiopathogenesis. Screening. Investigations. Target tissue resistance | Diabetes. Impaired glucose tolerance | Medical sciences | Endocrine pancreas. Apud cells (diseases) | Chromosomes, Human, Pair 8 - genetics | Genetic Predisposition to Disease - genetics | Zinc Transporter 8 | Diabetes Mellitus, Type 2 - genetics | Humans | Cation Transport Proteins - genetics | Chromosomes, Human, Pair 10 - genetics | France | Genome, Human | Case-Control Studies | Linkage Disequilibrium | Diabetes | Genomics | Risk factors | Polymorphism | Index Medicus | Genetic Predisposition to Disease | Chromosomes, Human, Pair 8 | Life Sciences | Genetics | Cation Transport Proteins | Diabetes Mellitus, Type 2 | Chromosomes, Human, Pair 10 | Human genetics
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2. Full Text A genome-wide association study of Hodgkin's lymphoma identifies new susceptibility loci at 2p16.1 (REL), 8q24.21 and 10p14 (GATA3)
by Enciso-Mora, Victor and Broderick, Peter and Ma, Yussanne and Jarrett, Ruth F and Hjalgrim, Henrik and Hemminki, Kari and van den Berg, Anke and Olver, Bianca and Lloyd, Amy and Dobbins, Sara E and Lightfoot, Tracy and van Leeuwen, Flora E and Foersti, Asta and Diepstra, Arjan and Broeks, Annegien and Vijayakrishnan, Jayaram and Shield, Lesley and Lake, Annette and Montgomery, Dorothy and Roman, Eve and Engert, Aneas and von Strandmann, Elke Pogge and Reiners, Katrin S and Nolte, Ilja M and Smedby, Karin E and Adami, Hans-Olov and Russell, Nicola S and Glimelius, Bengt and Hamilton-Dutoit, Stephen and de Bruin, Marieke and Ryder, Lars P and Molin, Daniel and Sorensen, Karina Meden and Chang, Ellen T and Taylor, Malcolm and Cooke, Rosie and Hofstra, Robert and Westers, Helga and van Wezel, Tom and van Eijk, Ronald and Ashworth, Alan and Rostgaard, Klaus and Melbye, Mads and Swerdlow, Anthony J and Houlston, Richard S
Nature genetics, ISSN 1061-4036, 12/2010, Volume 42, Issue 12, pp. 1126 - +
REED-STERNBERG CELLS | NEOPLASTIC-CELLS | GENE | INCREASED RISK | COLORECTAL-CANCER | PROSTATE-CANCER | DISEASE | INFECTIOUS-MONONUCLEOSIS | C-MYC | KAPPA-B-ALPHA | UMCG Approved | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Classical genetics, quantitative genetics, hybrids | Hematologic and hematopoietic diseases | Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Methods, theories and miscellaneous | GATA3 Transcription Factor - genetics | Chromosomes, Human, Pair 8 - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Hodgkin Disease - genetics | Chromosomes, Human - genetics | Humans | Genetic Loci - genetics | Male | Genome, Human - genetics | Chromosomes, Human, Pair 2 - genetics | Proto-Oncogene Proteins c-rel - genetics | Recombination, Genetic | Polymorphism, Single Nucleotide - genetics | Adult | Female | Chromosomes, Human, Pair 10 - genetics | Care and treatment | Histocompatibility antigens | HLA histocompatibility antigens | Development and progression | Genetic aspects | Disease susceptibility | Single nucleotide polymorphisms | Research | Health aspects | Hodgkin's disease | Studies | Medical research | Genotype & phenotype | Genetics | Principal components analysis | Grants | Health risk assessment | Epidemiology | Cancer | Index Medicus | Hälsovetenskap | Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi | Medical and Health Sciences | Medicin och hälsovetenskap | Public Health, Global Health, Social Medicine and Epidemiology | Health Sciences
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3. Full Text Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C
by Dryden, Nicola H and Broome, Laura R and Dudbridge, Frank and Johnson, Nichola and Orr, Nick and Schoenfelder, Stefan and Nagano, Takashi and Andrews, Simon and Wingett, Steven and Kozarewa, Iwanka and Assiotis, Ioannis and Fenwick, Kerry and Maguire, Sarah L and Campbell, James and Natrajan, Rachael and Lambros, Maryou and Perrakis, Eleni and Ashworth, Alan and Fraser, Peter and Fletcher, Olivia
Genome research, ISSN 1088-9051, 11/2014, Volume 24, Issue 11, pp. 1854 - 1868
Biochemistry & Molecular Biology | Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Chromosomes, Human, Pair 8 - genetics | Oligonucleotide Array Sequence Analysis | Homeodomain Proteins - metabolism | Humans | Breast Neoplasms - metabolism | Chromosomes, Human, Pair 2 - genetics | Chromosomes, Human, Pair 9 - genetics | Chromatin Immunoprecipitation | MCF-7 Cells | Real-Time Polymerase Chain Reaction | Genetic Predisposition to Disease - genetics | Reproducibility of Results | Chromosome Mapping | Hepatocyte Nuclear Factor 3-alpha - genetics | RNA, Long Noncoding - genetics | Sequence Analysis, DNA | Genome, Human - genetics | Homeodomain Proteins - genetics | Regulatory Sequences, Nucleic Acid - genetics | Hepatocyte Nuclear Factor 3-alpha - metabolism | Protein Interaction Mapping | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Cell Line, Tumor | Protein Binding | Polymorphism, Single Nucleotide | Genome-Wide Association Study - methods | RNA, Long Noncoding - metabolism | Genome-wide association studies | Usage | Chromosome mapping | Breast cancer | Genetic aspects | Research | Single nucleotide polymorphisms | Gene expression | Risk factors | Index Medicus | Method
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4. Full Text Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans
by Kathiresan, Sekar and Melander, Olle and Guiducci, Candace and Surti, Aarti and Burtt, Noël P and Rieder, Mark J and Cooper, Gregory M and Roos, Charlotta and Voight, Benjamin F and Havulinna, Aki S and Wahlstrand, Björn and Hedner, Thomas and Corella, Dolores and Tai, E. Shyong and Ordovas, Jose M and Berglund, Göran and Vartiainen, Erkki and Jousilahti, Pekka and Hedblad, Bo and Taskinen, Marja-Riitta and Newton-Cheh, Christopher and Salomaa, Veikko and Peltonen, Leena and Groop, Leif and Altshuler, David M and Orho-Melander, Marju and Sahlgrenska akademin and Institutionen för medicin, avdelningen för klinisk prövning och entreprenörskap and Institute of Medicine, Department of Clinical Trials and Entrepreneurship and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy
Nature genetics, ISSN 1061-4036, 2008, Volume 40, Issue 2, pp. 189 - 197
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Prospective Studies | Humans | Middle Aged | Male | RNA, Messenger - metabolism | Case-Control Studies | Genetic Variation | Chromosomes, Human, Pair 1 | Cholesterol, LDL - blood | Female | Gene Frequency | Liver - metabolism | Probability | Chromosomes, Human, Pair 8 | Genetic Markers | Cholesterol, HDL - genetics | Chromosomes, Human, Pair 7 | Sequence Analysis, DNA | Linkage Disequilibrium | Randomized Controlled Trials as Topic | Cholesterol, LDL - genetics | Chromosomes, Human, Pair 19 | Alleles | Triglycerides - blood | Cholesterol, HDL - blood | Aged | Polymorphism, Single Nucleotide | Triglycerides - genetics | Genome, Human | Cohort Studies | Type 2 diabetes | Proteolipids | Lipoproteins | Physiological aspects | Genetic aspects | Diagnosis | Research | Single nucleotide polymorphisms | Blood lipoproteins | Health aspects | Risk factors | Lipids | Gene loci | Triglycerides | Cholesterol | Index Medicus | RNA | Liver | Pair 1 | Klinisk medicin | Single Nucleotide | HDL | genetics | LDL | Chromosomes | Pair 7 | Pair 8 | Human | Messenger | blood | Variation (Genetics) | Clinical Medicine | DNA | Pair 19 | metabolism | Sequence Analysis | Genome | Polymorphism
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5. Full Text Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis
by Paternoster, Lavinia and Standl, Marie and Chen, Chih-Mei and Ramasamy, Adaikalavan and Bonnelykke, Klaus and Duijts, Liesbeth and Ferreira, Manuel A and Alves, Alexessander Couto and Thyssen, Jacob P and Albrecht, Eva and Baurecht, Hansjoerg and Feenstra, Bjarke and Sleiman, Patrick M. A and Hysi, Pirro and Warrington, Nicole M and Curjuric, Ivan and Myhre, Ronny and Curtin, John A and Groen-Blokhuis, Maria M and Kerkhof, Marjan and Saaf, Annika and Franke, Ane and Ellinghaus, David and Foelster-Holst, Regina and Dermitzakis, Emmanouil and Montgomery, Stephen B and Prokisch, Holger and Heim, Katharina and Hartikainen, Anna-Liisa and Pouta, Anneli and Pekkanen, Juha and Blakemore, Alexana I. F and Buxton, Jessica L and Kaakinen, Marika and Duffy, David L and Madden, Pamela A and Heath, Anew C and Montgomery, Grant W and Thompson, Philip J and Matheson, Melanie C and Le Souef, Peter and St Pourcain, Beate and Smith, George Davey and Henderson, John and Kemp, John P and Timpson, Nicholas J and Deloukas, Panos and Kim, Cecilia and Postma, Dirkje and Koppelman, Gerard H and Australian Asthma Genetics Consort and EArly Genetics Lifecourse Epidemio and Genetics Overweight Young Adults G and Genetics of Overweight Young Adults (GOYA) Consortium and Australian Asthma Genetics Consortium (AAGC) and EArly Genetics & Lifecourse Epidemiology (EAGLE) Consortium and The Genetics of Overweight Young Adults (GOYA) Consortium and the EArly Genetics & Lifecourse Epidemiology (EAGLE) Consortium and Institutionen för kliniska vetenskaper, Avdelningen för obstetrik och gynekologi and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Institute of Clinical Sciences, Department of Obstetrics and Gynecology and Sahlgrenska Academy
Nature genetics, ISSN 1061-4036, 02/2012, Volume 44, Issue 2, pp. 187 - 192
SPERMATOGENESIS | CELLULAR MOTILITY | VARIANTS | FILAGGRIN | DISEASE | ASTHMA | MECHANISMS | DIFFERENTIATION | EXPRESSION | UMCG Approved | PSORIASIS | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Immunopathology | Skin allergic diseases. Stinging insect allergies | Biological and medical sciences | Allergic diseases | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Dermatitis, Atopic - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Humans | Male | Risk | Chromosomes, Human, Pair 11 - genetics | Genetic Loci | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Chromosomes, Human, Pair 5 | Cell Differentiation - genetics | Epidermis - immunology | Dermatitis, Atopic - immunology | Intermediate Filament Proteins - genetics | Kinesin - genetics | Female | Polymorphism, Single Nucleotide | Cytokines - genetics | Chromosomes, Human, Pair 20 - genetics | Quantitative trait loci | Reports | Genetic aspects | Genetic susceptibility | Atopic dermatitis | Risk factors | Confidence intervals | Genomes | Mutation | Dermatitis | Allergies | Asthma | Meta-analysis | Index Medicus | Klinisk medicin | Clinical Medicine
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6. Full Text Prevalence, clinical characteristics, and prognosis of GATA2-related myelodysplastic syndromes in children and adolescents
by Wlodarski, Marcin W and Hirabayashi, Shinsuke and Pastor, Victor and Starý, Jan and Hasle, Henrik and Masetti, Riccardo and Dworzak, Michael and Schmugge, Markus and Van Den Heuvel-Eibrink, Marry and Ussowicz, Marek and De Moerloose, Barbara and Catala, Albert and Smith, Owen P and Sedlacek, Petr and Lankester, Arjan C and Zecca, Marco and Bordon, Victoria and Matthes-Martin, Susanne and Abrahamsson, Jonas and Kühl, Jörn Sven and Sykora, Karl-Walter and Albert, Michael H and Przychodzien, Bartlomiej and Maciejewski, Jaroslaw P and Schwarz, Stephan and Göhring, Gudrun and Schlegelberger, Brigitte and Cseh, Annámaria and Noellke, Peter and Yoshimi, Ayami and Locatelli, Franco and Baumann, Irith and Strahm, Brigitte and Niemeyer, Charlotte M and EWOG-MDS
Blood, ISSN 0006-4971, 03/2016, Volume 127, Issue 11, pp. 1387 - 1397
Life Sciences & Biomedicine | Hematology | Science & Technology | Chromosomes, Human, Pair 8 - genetics | Deafness - genetics | Prevalence | Prognosis | Prospective Studies | Humans | Child, Preschool | Male | GATA2 Transcription Factor - deficiency | Young Adult | Clinical Trials, Phase III as Topic | DNA Mutational Analysis | Germ-Line Mutation | Female | Chromosomes, Human, Pair 1 - genetics | Child | GATA2 Transcription Factor - genetics | Genetic Predisposition to Disease | Kaplan-Meier Estimate | Myelodysplastic Syndromes - epidemiology | Myelodysplastic Syndromes - etiology | Phenotype | Adolescent | Age of Onset | Chromosome Aberrations | Immunologic Deficiency Syndromes - genetics | Selection Bias | Myelodysplastic Syndromes - genetics | Chromosomes, Human, Pair 7 - genetics | Myelodysplastic Syndromes - pathology | Index Medicus | Abridged Index Medicus
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