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Nature Communications, ISSN 2041-1723, 06/2016, Volume 7, Issue 1, p. 11733
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2011, Volume 108, Issue 6, pp. 2450 - 2455
The full-length AML1-ETO (AE) fusion gene resulting from t(8;21) (q22;q22) in human acute myeloid leukemia (AML) is not sufficient to induce leukemia in... 
Cell growth | Receptors | 3T3 cells | NIH 3T3 cells | Myeloid leukemia | Leukemia | Mice | Transplantation | Genetic mutation | Blood | Interleukin-3 | Mouse model | Combinatorial therapy | Targeted therapy | Stem cell factor | TRANSCRIPTION FACTORS | GENE-MUTATIONS | targeted therapy | interleukin-3 | PROGNOSTIC IMPACT | stem cell factor | mouse model | MULTIDISCIPLINARY SCIENCES | FUSION GENE | MURINE MODEL | combinatorial therapy | MYELOPROLIFERATIVE DISEASE | EMBRYONIC LETHALITY | STI-571 INHIBITION | GASTROINTESTINAL STROMAL TUMORS | RECEPTOR TYROSINE KINASE | Chromosomes, Human, Pair 8 - genetics | NIH 3T3 Cells | Chromosomes, Human, Pair 21 - metabolism | Oncogene Proteins, Fusion - metabolism | Cytarabine - pharmacology | Humans | Leukemia, Myeloid, Acute - metabolism | Proto-Oncogene Proteins c-kit - metabolism | Cell Transformation, Neoplastic - genetics | Leukemia, Lymphoid - metabolism | Antimetabolites, Antineoplastic - pharmacology | Proto-Oncogene Proteins c-kit - genetics | Leukemia, Lymphoid - genetics | Protein Structure, Tertiary | Core Binding Factor Alpha 2 Subunit - metabolism | Leukemia, Myeloid, Acute - pathology | Mice, Transgenic | Leukemia, Lymphoid - pathology | Chromosomes, Human, Pair 21 - genetics | Cell Transformation, Neoplastic - metabolism | RUNX1 Translocation Partner 1 Protein | Chromosomes, Human, Pair 8 - metabolism | Animals | Oncogene Proteins, Fusion - genetics | Mutation | Cell Transformation, Neoplastic - pathology | Core Binding Factor Alpha 2 Subunit - genetics | Leukemia, Myeloid, Acute - genetics | Translocation, Genetic - genetics | Gene mutations | Health aspects | Biological Sciences
Journal Article
Journal Article
Prenatal Diagnosis, ISSN 0197-3851, 06/2015, Volume 35, Issue 6, pp. 612 - 619
Journal Article
Journal Article
Molecular Cancer Research, ISSN 1541-7786, 12/2005, Volume 3, Issue 12, pp. 655 - 667
Journal Article
Journal Article
Journal Article
Experimental & molecular medicine, ISSN 1226-3613, 04/2018, Volume 50, Issue 4, pp. 44 - 8
The AML1-ETO fusion protein (A/E), which results from the t(8;21) translocation, is considered to be a leukemia-initiating event. Identifying the mechanisms... 
AML1-ETO | MEDICINE, RESEARCH & EXPERIMENTAL | ACTIVATION | PROTEIN | REPRESSION | WT1 | ACETYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | BINDING-SITES | EXPRESSION | PROMOTE | BRAIN | Chromosomes, Human, Pair 8 - genetics | Translocation, Genetic | Chromosomes, Human, Pair 21 - metabolism | Oncogene Proteins, Fusion - metabolism | Humans | Leukemia, Myeloid, Acute - metabolism | DNA Methylation | Cell Transformation, Neoplastic - genetics | U937 Cells | Nerve Tissue Proteins - biosynthesis | RUNX1 Translocation Partner 1 Protein - genetics | RUNX1 Translocation Partner 1 Protein - metabolism | Core Binding Factor Alpha 2 Subunit - metabolism | Leukemia, Myeloid, Acute - pathology | Membrane Proteins - genetics | Gene Silencing | THP-1 Cells | Repressor Proteins - genetics | Chromosomes, Human, Pair 21 - genetics | Cell Transformation, Neoplastic - metabolism | Nerve Tissue Proteins - genetics | Chromosomes, Human, Pair 8 - metabolism | Membrane Proteins - biosynthesis | Repressor Proteins - biosynthesis | Oncogene Proteins, Fusion - genetics | HL-60 Cells | Cell Transformation, Neoplastic - pathology | Core Binding Factor Alpha 2 Subunit - genetics | Leukemia, Myeloid, Acute - genetics | Nucleotide sequence | Myeloid leukemia | Leukemia | AML1 protein | Cell lines | Cell cycle | DNA methylation | Leukemogenesis | DNA methyltransferase | Fusion protein | Methylation | Acute myeloid leukemia | Binding sites | Apoptosis | 5-aza-2'-deoxycytidine | 생화학
Journal Article
Journal Article