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Journal of Bone and Mineral Research, ISSN 0884-0431, 08/2012, Volume 27, Issue 8, pp. 1757 - 1772
Chronic kidney disease–mineral bone disorder (CKD‐MBD) is defined by abnormalities in mineral and hormone metabolism, bone histomorphometric changes, and/or... 
RENAL OSTEODYSTROPHY | OSTEOCYTE | WNT/β‐CATENIN | WNT/β-CATENIN | AORTIC CALCIFICATION | VASCULAR CALCIFICATION | ss-CATENIN | MINERAL BONE DISORDER | BETA-CATENIN | NONDIALYZED PATIENTS | CORONARY-ARTERY CALCIFICATION | ENDOCRINOLOGY & METABOLISM | CARDIOVASCULAR-DISEASE | HEMODIALYSIS-PATIENTS | PARATHYROID-HORMONE | WNT | CHRONIC KIDNEY-DISEASE | Bone and Bones - pathology | Chronic Kidney Disease-Mineral and Bone Disorder - pathology | Chronic Kidney Disease-Mineral and Bone Disorder - blood | Humans | Middle Aged | Chronic Kidney Disease-Mineral and Bone Disorder - physiopathology | Glycoproteins - metabolism | Cardiovascular Abnormalities - blood | Male | Chronic Kidney Disease-Mineral and Bone Disorder - metabolism | Gene Expression Profiling | Cardiovascular Abnormalities - pathology | Cardiovascular Abnormalities - physiopathology | Kidney Failure, Chronic - pathology | Bone and Bones - metabolism | Female | Kidney Failure, Chronic - physiopathology | Osteoclasts - pathology | Cardiovascular Abnormalities - complications | Osteocytes - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Protein-Serine-Threonine Kinases - genetics | Mutation - genetics | Osteoclasts - metabolism | Disease Progression | Animals | Kidney Failure, Chronic - blood | Wnt Signaling Pathway - genetics | Biopsy | Calcification, Physiologic | Kidney Failure, Chronic - complications | Osteocytes - pathology | Mice | Bone Remodeling | NIMA-Related Kinases | Vascular Calcification | Calcification (ectopic) | Renal function | Renal osteodystrophy | Wnt protein | Polycystic kidney | catenin | Osteocytes | Bone diseases | Minerals | Gene expression | Osteoprotegerin | Gene silencing | Signal transduction | NF- Kappa B protein | Osteoclasts | Kidney diseases | TRANCE protein | Age | Osteogenesis
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 06/2011, Volume 26, Issue 6, pp. 1368 - 1376
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 07/2012, Volume 122, Issue 7, pp. 2543 - 2553
Chronic kidney disease-mineral and bone disorder (CKD-MBD) is associated with secondary hyperparathyroidism (HPT) and serum elevations in the phosphaturic... 
MEDICINE, RESEARCH & EXPERIMENTAL | FAMILIAL TUMORAL CALCINOSIS | VITAMIN-D METABOLISM | CARDIOVASCULAR EVENTS | VASCULAR CALCIFICATION | HEMODIALYSIS-PATIENTS | PARATHYROID-HORMONE | PHYSIOLOGICAL-ROLE | FIBROBLAST GROWTH FACTOR-23 | LEFT-VENTRICULAR HYPERTROPHY | STAGE RENAL-DISEASE | Chronic Kidney Disease-Mineral and Bone Disorder - blood | Kidney - pathology | Chronic Kidney Disease-Mineral and Bone Disorder - physiopathology | Hyperparathyroidism, Secondary - physiopathology | Male | Chronic Kidney Disease-Mineral and Bone Disorder - metabolism | Parathyroid Hormone - blood | Tibia - pathology | Fibroblast Growth Factors - immunology | Luciferases - genetics | Renal Insufficiency, Chronic - metabolism | Calcium - blood | Fibroblast Growth Factors - metabolism | Phosphates - blood | Tibia - metabolism | Genes, Reporter | Kidney - physiopathology | CHO Cells | Biomarkers - metabolism | Cricetinae | Hyperparathyroidism, Secondary - metabolism | Glomerular Filtration Rate | Rats | Myocardium - pathology | Vascular Calcification - pathology | Calcitriol - blood | Rats, Sprague-Dawley | Renal Insufficiency, Chronic - physiopathology | Aorta - pathology | Renal Insufficiency, Chronic - blood | Hyperparathyroidism, Secondary - blood | Animals | Mice | Mice, Inbred BALB C | Fibroblast Growth Factors - antagonists & inhibitors | Hemodynamics | Antibodies, Monoclonal, Murine-Derived - pharmacology | Luciferases - biosynthesis | Complications and side effects | United States | Mortality | Research | Kidney diseases | Hyperparathyroidism | Risk factors
Journal Article
Kidney International, ISSN 0085-2538, 01/2018, Volume 93, Issue 1, pp. 147 - 158
We examined activin receptor type IIA (ActRIIA) activation in chronic kidney disease (CKD) by signal analysis and inhibition in mice with Alport syndrome using... 
cardiovascular disease | chronic kidney disease | bone | fibrosis | mineral metabolism | vascular calcification | TGF-BETA | CARDIOVASCULAR EVENTS | RENAL FIBROSIS | ARTERIAL CALCIFICATION | BONE MORPHOGENETIC PROTEIN-7 | GROWTH-FACTOR 23 | UROLOGY & NEPHROLOGY | SMOOTH-MUSCLE-CELLS | LINKED ALPORT-SYNDROME | OSTEOCLAST DIFFERENTIATION | ATHEROSCLEROTIC LESION | Kidney - pathology | Recombinant Fusion Proteins - pharmacology | Blood Vessels - metabolism | Chronic Kidney Disease-Mineral and Bone Disorder - metabolism | Core Binding Factor Alpha 1 Subunit - metabolism | Chronic Kidney Disease-Mineral and Bone Disorder - genetics | Vascular Calcification - metabolism | Kidney - metabolism | Bone Resorption - genetics | Bone and Bones - metabolism | Myocardium - metabolism | Renal Insufficiency, Chronic - genetics | Bone Resorption - metabolism | Disease Models, Animal | Bone Resorption - physiopathology | Glomerular Filtration Rate | Signal Transduction | Smad2 Protein - metabolism | Cardiomegaly - physiopathology | Nephritis, Hereditary - genetics | Renal Insufficiency, Chronic - physiopathology | Mice, Knockout | Renal Insufficiency, Chronic - prevention & control | Cardiomegaly - prevention & control | Nephritis, Hereditary - metabolism | Collagen Type IV - deficiency | Activin Receptors, Type II - genetics | Fibrosis | Sp7 Transcription Factor - metabolism | Collagen Type IV - genetics | Cardiomegaly - metabolism | Activin Receptors, Type II - metabolism | Bone and Bones - pathology | Phosphorylation | Vascular Remodeling | Blood Vessels - pathology | Vascular Calcification - genetics | Actins - metabolism | Chronic Kidney Disease-Mineral and Bone Disorder - physiopathology | Activin Receptors, Type II - antagonists & inhibitors | Blood Vessels - physiopathology | Renal Insufficiency, Chronic - metabolism | Ventricular Remodeling | Chronic Kidney Disease-Mineral and Bone Disorder - prevention & control | Muscle Proteins - metabolism | Vascular Calcification - physiopathology | Microfilament Proteins - metabolism | Nephritis, Hereditary - physiopathology | Kidney - physiopathology | Vascular Calcification - prevention & control | Myocardium - pathology | Bone Resorption - prevention & control | Bone and Bones - physiopathology | Animals | Nephritis, Hereditary - drug therapy | Cardiomegaly - genetics | Bone Remodeling | Chronic kidney disease
Journal Article
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 10/2018, Volume 106, pp. 54 - 60
Chronic kidney disease-mineral and bone disorder (CKD-MBD) play a critical role in the pathogenesis of cardiovascular complications in patients with chronic... 
Zuogui pill | Chronic kidney disease | Nourish kidney | Mineral and bone disorder | Bone metabolism | MEDICINE, RESEARCH & EXPERIMENTAL | VITAMIN-D | DIURETIC ACTIVITY | VASCULAR CALCIFICATION | QUALITY-CONTROL | PORIA-COCOS | METABOLOMICS | METABOLISM | TRADITIONAL USES | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY | CHRONIC-RENAL-FAILURE | Chronic Kidney Disease-Mineral and Bone Disorder - pathology | Chronic Kidney Disease-Mineral and Bone Disorder - blood | Kidney - pathology | Rats, Wistar | Chronic Kidney Disease-Mineral and Bone Disorder - physiopathology | 25-Hydroxyvitamin D3 1-alpha-Hydroxylase - genetics | Drugs, Chinese Herbal - pharmacology | Parathyroid Hormone - blood | Bone Remodeling - drug effects | Bone and Bones - drug effects | Parathyroid Hormone - genetics | Sodium-Phosphate Cotransporter Proteins, Type IIa - metabolism | Calcium - blood | Kidney - metabolism | Bone and Bones - metabolism | Core Binding Factor Alpha 1 Subunit - blood | Kidney - physiopathology | Disease Models, Animal | Kidney - drug effects | 25-Hydroxyvitamin D3 1-alpha-Hydroxylase - metabolism | Chronic Kidney Disease-Mineral and Bone Disorder - drug therapy | Sodium-Phosphate Cotransporter Proteins, Type IIa - genetics | Bone Density - drug effects | Bone and Bones - physiopathology | Animals | Fibroblast Growth Factors - blood | Phosphorus - blood | Creatinine - blood | Chronic kidney failure | RNA | Parathyroid hormone | Analysis | Cardiac patients | Cytochrome P-450 | Health aspects
Journal Article
International Urology and Nephrology, ISSN 0301-1623, 10/2018, Volume 50, Issue 10, pp. 1863 - 1870
The complexity of chronic kidney disease–mineral and bone disorder (CKD–MBD) led to many preclinical and clinical trials. The role of sclerostin in renal... 
Nephrology | Biomarker | Medicine & Public Health | Intima-media thickness | Sclerostin | Chronic kidney disease | Mineral and bone disorder | Urology | MORTALITY | PREVALENT HEMODIALYSIS-PATIENTS | VASCULAR CALCIFICATION | THERAPY | PATHWAY | FGF-23 | UROLOGY & NEPHROLOGY | RENAL OSTEODYSTROPHY | CKD | PROGRESSION | Chronic Kidney Disease-Mineral and Bone Disorder - blood | Chronic Kidney Disease-Mineral and Bone Disorder - complications | Glycated Hemoglobin A - metabolism | Humans | Middle Aged | Chronic Kidney Disease-Mineral and Bone Disorder - physiopathology | Male | Bone Morphogenetic Proteins - blood | Parathyroid Hormone - blood | Calcium - blood | Atherosclerosis - diagnostic imaging | Aged, 80 and over | Phosphates - blood | Adult | Female | Alkaline Phosphatase - blood | Glomerular Filtration Rate | Carotid Intima-Media Thickness | Atherosclerosis - complications | Biomarkers - blood | Genetic Markers | Atherosclerosis - blood | Fibroblast Growth Factors - blood | Sex Factors | Creatinine - blood | Aged | Phosphates | Care and treatment | Phosphatases | Chronic kidney failure | Analysis | Atherosclerosis | Epidemiology | Creatinine | Alkaline phosphatase | Kidneys | Epidermal growth factor receptors | Fibroblast growth factor 23 | Clinical trials | SOST protein | Bone diseases | Glomerular filtration rate | Calcium phosphates | Serum levels | Calcium (blood) | Parathyroid hormone | Arteriosclerosis | Kidney diseases | Parathyroid | Ultrasound
Journal Article
Nephrology Dialysis Transplantation, ISSN 0931-0509, 08/2012, Volume 27, Issue 8, pp. 3063 - 3071
Journal Article
Clinical Journal of the American Society of Nephrology, ISSN 1555-9041, 07/2017, Volume 12, Issue 7, pp. 1118 - 1127
Background and objectives The relationship between mineral and bone disorders and survival according to residual kidney function status has not been previously... 
Alkaline phosphatase | Renal function | Calcium | Hemodialysis | Humans | Mortality | Phosphorus | Risk | Minerals | Follow-up studies | Mineral metabolism | Phosphorus, Dietary | Urea | Albumins | Chronic kidney failure | Parathyroid hormone | End stage kidney disease | Renal dialysis | Urinary tract physiological phenomena | Proportional hazards models | SERUM ALKALINE-PHOSPHATASE | INDOXYL SULFATE | PHOSPHORUS | DIALYSIS PATIENTS | SKELETAL RESISTANCE | PROTEIN CATABOLIC RATE | VASCULAR CALCIFICATION | CALCIUM | UROLOGY & NEPHROLOGY | PARATHYROID-HORMONE | RISK | Kidney Diseases - physiopathology | Chronic Kidney Disease-Mineral and Bone Disorder - blood | United States | Blood Urea Nitrogen | Middle Aged | Chronic Kidney Disease-Mineral and Bone Disorder - physiopathology | Male | Parathyroid Hormone - blood | Urea - blood | Calcium - blood | Kidney - metabolism | Renal Dialysis - mortality | Time Factors | Chronic Kidney Disease-Mineral and Bone Disorder - mortality | Female | Kidney Diseases - blood | Retrospective Studies | Alkaline Phosphatase - blood | Kidney - physiopathology | Risk Factors | Proportional Hazards Models | Kidney Diseases - mortality | Treatment Outcome | Biomarkers - blood | Renal Elimination | Phosphorus - blood | Renal Dialysis - adverse effects | Kidney Diseases - therapy | Aged | parathyroid hormone | calcium | end stage kidney disease | Follow-Up Studies | Urinary Tract Physiological Phenomena | Alkaline Phosphatase | chronic kidney failure | urea | mineral metabolism | hemodialysis | renal function | Original | renal dialysis
Journal Article