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Journal Article
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 01/2015, Volume 112, Issue 2, pp. E166 - E175
The breakthrough development of clinically effective immune checkpoint inhibitors illustrates the potential of T-cell-based immunotherapy to effectively treat... 
tumor-associated antigens | MULTIDISCIPLINARY SCIENCES | VACCINE | CD4(+) T-CELLS | ANTIGENS | CANCER-IMMUNOTHERAPY | chronic lymphocytic leukemia | MEMORY | therapeutic vaccination | cancer immunotherapy | TARGETS | PATIENT | HLA | IPILIMUMAB | EPITOPES
Journal Article
Annals of Oncology, ISSN 1569-8041, 03/2013, Volume 24, Issue 3, pp. 561 - 76
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2014, Volume 111, Issue 38, pp. 13906 - 13911
The Bruton tyrosine kinase inhibitor (BTKi) ibrutinib is a new targeted therapy for patients with chronic lymphocytic leukemia (CLL). Ibrutinib is given orally... 
Disease resistance | Chronic lymphocytic leukemia | Relapse | Cell growth | B lymphocytes | Mortality | Population size | Genetic mutation | Blood | Tumors | Mathematical models | Stochastic dynamics | Drug resistance | Personalized medicine | Evolutionary dynamics | B-CELL RECEPTOR | MULTIDISCIPLINARY SCIENCES | evolutionary dynamics | mathematical models | TISSUE | PCI-32765 | MECHANISMS | KINASE INHIBITOR IBRUTINIB | TARGETING BTK | CANCER | personalized medicine | stochastic dynamics | THERAPY | IN-VIVO | MUTATION | drug resistance | Prognosis | Protein-Tyrosine Kinases - metabolism | Pyrimidines - administration & dosage | Humans | Neoplasm Proteins - antagonists & inhibitors | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | Neoplasm Proteins - metabolism | Drug Resistance, Neoplasm - genetics | Leukemia, Lymphocytic, Chronic, B-Cell - enzymology | Protein-Tyrosine Kinases - genetics | Pyrazoles - administration & dosage | Models, Biological | Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy | Mutation | Neoplasm Proteins - genetics | Drug Resistance, Neoplasm - drug effects | Evolution, Molecular | Leukemia, Lymphocytic, Chronic, B-Cell - diagnosis | Protein-Tyrosine Kinases - antagonists & inhibitors | Pharmaceutical research | Care and treatment | Drug interactions | Oncology, Experimental | Research | Drug therapy | Cancer | Biological Sciences
Journal Article
Journal Article
British Journal of Haematology, ISSN 0007-1048, 04/2016, Volume 173, Issue 1, pp. 105 - 113
This study revisited the Dohner prognostic hierarchy in a cohort of 1585 well‐documented patients with chronic lymphocytic leukaemia. The duration of both time... 
leukaemia | chronic lymphocytic leukaemia | cytogenetics | hybridization | fluorescence | in situ | Cytogenetics | Chronic lymphocytic leukaemia | Fluorescence in situ hybridization | Leukaemia | Fluorescence | Analysis | fluorescence in situ hybridization | Research Paper | Haematological Malignancy
Journal Article
Deutsche Medizinische Wochenschrift, ISSN 0012-0472, 2018, Volume 143, Issue 18, pp. 1318 - 1324
Journal Article
Cancer, ISSN 0008-543X, 05/2019, Volume 125, Issue 9, pp. 1432 - 1440
Within a period of just over a decade, managing chronic lymphocytic leukemia (CLL) has become more effective and yet more challenging than ever before. The... 
chemoimmunotherapy is right for some | chronic lymphocytic leukemia | sequencing new agents | targeted newer agents | treatment options |