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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2006, Volume 103, Issue 10, pp. 3896 - 3901
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 11/2002, Volume 22, Issue 21, pp. 9228 - 9236
Activation of microglia commonly occurs in response to a wide variety of pathological stimuli including trauma, axotomy, ischemia, and degeneration in the CNS.... 
Müller glial cell | Photoreceptor | Retinal degeneration | Glia-glia interaction | Neurotrophins | Glia-neuron interaction | Microglia | retinal degeneration | MESSENGER-RNA EXPRESSION | photoreceptor | FOS GENE-EXPRESSION | RECEPTOR EXPRESSION | FIBROBLAST-GROWTH-FACTOR | glia-glia interaction | NEUROSCIENCES | SIGNAL-SEQUENCE | IN-VITRO | ROD PHOTORECEPTORS | CNTF RECEPTOR | RAT-BRAIN MICROGLIA | Muller glial cell | CENTRAL-NERVOUS-SYSTEM | microglia | neurotrophins | glia-neuron interaction | Brain-Derived Neurotrophic Factor - genetics | Microglia - metabolism | Nerve Growth Factor - biosynthesis | Rats, Wistar | Neuroglia - pathology | Receptors, Nerve Growth Factor - metabolism | Microglia - radiation effects | RNA, Messenger - metabolism | Retinal Degeneration - metabolism | Glial Cell Line-Derived Neurotrophic Factor | Ciliary Neurotrophic Factor - genetics | Microglia - pathology | Ciliary Neurotrophic Factor - biosynthesis | Brain-Derived Neurotrophic Factor - biosynthesis | Photoreceptor Cells - pathology | Disease Models, Animal | Retina - radiation effects | Light - adverse effects | Mice, Inbred C57BL | Cells, Cultured | Rats | Nerve Growth Factor - genetics | Nerve Growth Factors - biosynthesis | Receptor, Nerve Growth Factor | Photoreceptor Cells - radiation effects | Receptors, Nerve Growth Factor - genetics | Cell Movement - radiation effects | Mice, Knockout | Neuroglia - radiation effects | Neurotrophin 3 - biosynthesis | Animals | Nerve Growth Factors - genetics | Neuroglia - metabolism | Mice | Receptors, Nerve Growth Factor - deficiency | Retinal Degeneration - pathology | Retina - pathology | ARTICLE | glia–glia interaction | glia–neuron interaction
Journal Article
Pharmacology and Therapeutics, ISSN 0163-7258, 2007, Volume 115, Issue 2, pp. 292 - 306
Nerve growth factor (NGF) and other members of the neurotrophin family are critical for the survival and differentiation of neurons and have been implicated in... 
Clinical trials | Nerve growth factor | Neurodegenerative disease | Brain-derived neurotrophic factor | Neurotrophins | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | SIGNALING PATHWAYS | neurodegenerative disease | ALZHEIMERS-DISEASE | AMYOTROPHIC-LATERAL-SCLEROSIS | NERVE GROWTH-FACTOR | nerve growth factor | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY | clinical trials | SPINAL-CORD-INJURY | brain-derived neurotrophic factor | PC12 CELLS | NEUROIMMUNOPHILIN LIGANDS | neurotrophins | PARKINSONS-DISEASE | Spinal Cord Injuries - drug therapy | Nerve Growth Factor - biosynthesis | Obesity - drug therapy | Receptors, Nerve Growth Factor - drug effects | Humans | Receptors, Nerve Growth Factor - physiology | Neurodegenerative Diseases - drug therapy | Amyotrophic Lateral Sclerosis - drug therapy | Depression - drug therapy | Depression - metabolism | Brain-Derived Neurotrophic Factor - physiology | Nerve Growth Factor - physiology | Brain-Derived Neurotrophic Factor - biosynthesis | Brain-Derived Neurotrophic Factor - therapeutic use | Nerve Growth Factors - physiology | Wound Healing - drug effects | Signal Transduction | Spinal Cord Injuries - metabolism | Neurodegenerative Diseases - metabolism | Nerve Growth Factors - biosynthesis | Nerve Growth Factor - therapeutic use | Nerve Growth Factors - therapeutic use | Obesity - metabolism | Peripheral Nervous System Diseases - metabolism | Animals | Amyotrophic Lateral Sclerosis - metabolism | Peripheral Nervous System Diseases - drug therapy | Serotonin uptake inhibitors | Cyclic adenylic acid | Adenylic acid | Ciliary neurotrophic factor
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 06/2010, Volume 30, Issue 22, pp. 7516 - 7527
The development of novel therapeutic strategies for Alzheimer's disease (AD) represents one of the biggest unmet medical needs today. Application of... 
NEURONAL APOPTOSIS | TROPHIC FACTORS | AMYLOID-BETA-PEPTIDE | A-BETA | SOLUBLE OLIGOMERS | MILD COGNITIVE IMPAIRMENT | FACTOR GENE-THERAPY | HUNTINGTONS-DISEASE | NEUROSCIENCES | TRANSGENIC MICE | PARKINSONS-DISEASE | Enzyme-Linked Immunosorbent Assay - methods | Cell- and Tissue-Based Therapy - methods | Alzheimer Disease - complications | Amyloid beta-Peptides - pharmacology | Humans | Apoptosis - genetics | Male | Peptide Fragments - pharmacology | Green Fluorescent Proteins - genetics | Synaptosomes - metabolism | Ciliary Neurotrophic Factor - administration & dosage | Synapses - metabolism | Synaptosomes - pathology | Transfection - methods | Time Factors | Amyloid beta-Peptides - metabolism | Ciliary Neurotrophic Factor - biosynthesis | Neurons - metabolism | Amyloid beta-Peptides - administration & dosage | Neurons - drug effects | Disease Models, Animal | Synapses - drug effects | Maze Learning - physiology | Gene Expression Regulation - genetics | Mice, Inbred C57BL | Peptide Fragments - administration & dosage | Cells, Cultured | Enzyme Inhibitors - pharmacology | Ciliary Neurotrophic Factor - therapeutic use | Mice, Transgenic | Mutation - genetics | Synaptosomes - ultrastructure | Gene Expression Regulation - drug effects | Amyloid beta-Protein Precursor - genetics | Animals | Cell Count - methods | Memory Disorders - etiology | Signal Transduction - drug effects | Memory Disorders - therapy | Brain - pathology | Mice | Alzheimer Disease - genetics
Journal Article
Rheumatology (United Kingdom), ISSN 1462-0324, 07/2012, Volume 51, Issue 7, pp. 1161 - 1165
Objectives. Histological examination of pathological tendon generally does not reveal signs of inflammation. However, the inflammatory cytokine IL-6 has been... 
Posterior tibialis tendon | Tendon rupture | CNTF | LIF | OSM | Tendinopathy | Achilles tendon | Gene expression | IL-6 | ONCOSTATIN M | RESORPTION | PORCINE ARTICULAR-CARTILAGE | tendon rupture | posterior tibialis tendon | TENDINOSIS | RHEUMATOLOGY | INTERLEUKIN-6 | PROTEOGLYCAN | MESSENGER-RNA | GROWTH-FACTOR | HUMAN ACHILLES-TENDON | gene expression | tendinopathy | Immunohistochemistry | Vascular Endothelial Growth Factor A - biosynthesis | Achilles Tendon - pathology | Tendinopathy - metabolism | Posterior Tibial Tendon Dysfunction - etiology | Humans | Middle Aged | Tendinopathy - etiology | Posterior Tibial Tendon Dysfunction - metabolism | Male | Vascular Endothelial Growth Factor A - genetics | Cyclooxygenase 2 - biosynthesis | RNA, Messenger - biosynthesis | Collagen Type I - genetics | Cyclooxygenase 2 - genetics | Ciliary Neurotrophic Factor - genetics | Ciliary Neurotrophic Factor - biosynthesis | Female | Tendon Injuries - metabolism | Real-Time Polymerase Chain Reaction | Tendon Injuries - genetics | Fibroblasts - metabolism | Severity of Illness Index | Interleukin-6 - genetics | RNA, Messenger - genetics | Cells, Cultured | Gene Expression Regulation | Rupture | Posterior Tibial Tendon Dysfunction - genetics | Fibroblasts - pathology | Achilles Tendon - injuries | Tendon Injuries - complications | Collagen Type I - biosynthesis | Tendinopathy - genetics | Achilles Tendon - metabolism | Interleukin-6 - biosynthesis | Family | Chronic Disease | Cadaver | Basic Science
Journal Article
Journal Article
Molecular and Cellular Neuroscience, ISSN 1044-7431, 2009, Volume 41, Issue 3, pp. 313 - 324
Journal Article
Neurochemical Research, ISSN 0364-3190, 11/2015, Volume 40, Issue 11, pp. 2333 - 2347
Ciliary neurotrophic factor (CNTF) is a promyelinating trophic factor that plays an important role in multiple sclerosis (MS). However, mechanisms by which... 
Neurochemistry | Biochemistry, general | Neurology | Neurosciences | CNTF | Biomedicine | Sodium benzoate | CREB | Astrocytes | Oligodendrocytes | PKA | Cell Biology | GEMFIBROZIL | CELLS | NEURODEGENERATIVE-DISORDERS | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEUROSCIENCES | LIPID-LOWERING DRUG | THERAPY | MYELIN | MULTIPLE-SCLEROSIS | DISEASE | NEURONS | Oligodendroglia - metabolism | Humans | Gene Knockdown Techniques | RNA, Messenger - biosynthesis | Sodium Benzoate - antagonists & inhibitors | Isoquinolines - pharmacology | Oligodendroglia - drug effects | Ciliary Neurotrophic Factor - biosynthesis | Sodium Benzoate - pharmacology | Cyclic AMP-Dependent Protein Kinases - metabolism | Astrocytes - drug effects | Cyclic AMP Response Element-Binding Protein - biosynthesis | Cinnamomum zeylanicum - metabolism | Encephalomyelitis, Autoimmune, Experimental - drug therapy | Mice, Inbred C57BL | RNA, Messenger - genetics | Food Preservatives - pharmacology | Enzyme Activation - drug effects | Sulfonamides - pharmacology | Up-Regulation - drug effects | Cyclic AMP Response Element-Binding Protein - genetics | Animals | Encephalomyelitis, Autoimmune, Experimental - enzymology | Mice | Primary Cell Culture | Astrocytes - metabolism | Multiple sclerosis | Metabolites | RNA | Analysis | Food additives | Binding proteins | Ciliary neurotrophic factor | Protein binding | Monoglycerides
Journal Article
Journal Article
Physiological Genomics, ISSN 1094-8341, 02/2008, Volume 32, Issue 3, pp. 393 - 400
The purpose of this investigation was to compare expression of genes that function in inflammation and stress, cell structure and signaling, or remodeling and... 
Metallopeptidase | Myostatin | Ciliary neurotrophic factor | Growth factors | Alpha cardiac actin | PHYSIOLOGY | PROTEIN | growth factors | MUSCULAR STRENGTH | alpha cardiac actin | HEALTHY-YOUNG | ciliary neurotrophic factor | myostatin | CELL BIOLOGY | MATRIX METALLOPROTEINASES | WOMEN | MESSENGER-RNA | ALPHA-SKELETAL | metallopeptidase | GENETICS & HEREDITY | FACTOR CNTF | OLDER MEN | Tissue Inhibitor of Metalloproteinase-1 - biosynthesis | Humans | Intercellular Signaling Peptides and Proteins - biosynthesis | Male | Muscle, Skeletal - metabolism | Gene Expression Profiling | Insulin-Like Growth Factor I - genetics | Transforming Growth Factor beta - biosynthesis | Actins - genetics | Muscle Proteins - biosynthesis | Rest - physiology | RNA, Messenger - biosynthesis | Aging - genetics | Insulin-Like Growth Factor Binding Protein 5 - biosynthesis | Ciliary Neurotrophic Factor - genetics | Adult | Ciliary Neurotrophic Factor - biosynthesis | Weight Lifting - physiology | Matrix Metalloproteinase 2 - biosynthesis | Insulin-Like Growth Factor I - biosynthesis | Actins - biosynthesis | Muscle, Skeletal - growth & development | RNA, Messenger - genetics | Intercellular Signaling Peptides and Proteins - genetics | Gene Expression Regulation - physiology | Reverse Transcriptase Polymerase Chain Reaction | Muscle Proteins - genetics | Matrix Metalloproteinase 2 - genetics | Tissue Inhibitor of Metalloproteinase-1 - genetics | Transforming Growth Factor beta - genetics | Aged | Insulin-Like Growth Factor Binding Protein 5 - genetics | Aging - metabolism
Journal Article