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Trends in Cell Biology, ISSN 0962-8924, 2016, Volume 27, Issue 2, pp. 126 - 140
Journal Article
Current Biology, ISSN 0960-9822, 12/2015, Volume 25, Issue 23, pp. R1143 - R1150
Journal Article
Analytical Chemistry, ISSN 0003-2700, 02/2018, Volume 90, Issue 4, pp. 2891 - 2895
Primary cilia are hair-like sensory organelles whose dimensions and location vary with cell type and culture condition. Herein, we employed scanning ion... 
CELLS | CHEMISTRY, ANALYTICAL | ATOMIC-FORCE MICROSCOPY | RESORPTION | CILIOGENESIS
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2017, Volume 114, Issue 40, pp. 10660 - 10665
MicroRNAs (miRNAs) have been known to affect various biological processes by repressing expression of specific genes. Here we describe an essential function of... 
Ciliogenesis | Epithelial differentiation | miR-34 | Cyclins | Cell cycle | MOTILE CILIOGENESIS | SPERMATOGENESIS | APOPTOSIS | MIR-34A | epithelial differentiation | cell cycle | cyclins | MULTIDISCIPLINARY SCIENCES | FEEDBACK LOOP | P53 | ciliogenesis | GROWTH ARREST | PROSTATE-CANCER | TUMOR-SUPPRESSOR | MIRNAS | Cell research | Genetic aspects | MicroRNA | Research | Cell differentiation | Biological Sciences
Journal Article
CURRENT BIOLOGY, ISSN 0960-9822, 09/2007, Volume 17, Issue 18, pp. 1586 - 1594
The assembly of primary cilia is dependant on intraflagellar transport (IFT), which mediates the bidirectional movement of proteins between the base and tip of... 
LEPTIN | HYPERTROPHY | PROTEIN | GENE | KINESIN-II | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | NEURONS | CILIOGENESIS | KIF3A SUBUNIT | PRIMARY CILIUM | CELL BIOLOGY
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 11/2018, Volume 9
Multiciliated cells (MCCs) harbor dozens to hundreds of motile cilia, which generate hydrodynamic forces important in animal physiology. In vertebrates, MCC... 
MOTILE CILIOGENESIS | MULTICILIOGENESIS | ASTRIN | AMPLIFICATION | BIOGENESIS | EPITHELIUM | GEMC1 | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | DUPLICATION | DIFFERENTIATION
Journal Article
Cytoskeleton, ISSN 1949-3584, 10/2018, Volume 75, Issue 10, pp. C4 - C4
The back‐cover image is based on the Short Report The small molecule AMBMP disrupts microtubule growth, ciliogenesis, cell polarity and cell migration by M.E.... 
microtubule | small molecule | Wnt signaling | cell polarity | ciliogenesis
Journal Article
CLINICAL CANCER RESEARCH, ISSN 1078-0432, 07/2019, Volume 25, Issue 13, pp. 4179 - 4193
Purpose: For many tumors, signaling exchanges between cancer cells and other cells in their microenvironment influence overall tumor signaling. Some of these... 
ACTIVATION | ONCOLOGY | PATHWAY | MOUSE MODEL | CELL-CYCLE | CILIOGENESIS | INHIBITORS | SUPPRESSES CYST GROWTH | PRIMARY CILIUM | AURORA-A | HEDGEHOG
Journal Article
Development (Cambridge), ISSN 0950-1991, 03/2019, Volume 146, Issue 6, p. dev172643
Motile cilia on multiciliated cells (MCCs) function in fluid clearance over epithelia. Studies with Xenopus embryos and individuals with the congenital... 
E2F | Multiciliated cell | GMNC | MCIDAS | Deuterosome | Cilia | DEVELOPMENTAL BIOLOGY | GEMC1 | BIOGENESIS | REGULATORS | CENTRIOLE AMPLIFICATION | CILIOGENESIS | E2F4
Journal Article
Nature Cell Biology, ISSN 1465-7392, 01/2012, Volume 14, Issue 1, pp. 61 - 72
Using RNAi screening, proteomics, cell biological and mouse genetics approaches, we have identified a complex of nine proteins, seven of which are disrupted in... 
DISEASE GENES | REGULATOR | OUTER SEGMENT DEVELOPMENT | DISRUPTION | MKS1 | GENERATION | CILIOGENESIS | PROTEINS | CC2D2A | BODY | CELL BIOLOGY | Synthesis | RNA | Cilia and ciliary motion | Growth | Genetic aspects | Cellular signal transduction | Research | Properties | Membrane proteins
Journal Article
Cell Cycle, ISSN 1538-4101, 8/2014, Volume 13, Issue 15, pp. 2315 - 2316
Journal Article
Cell Reports, ISSN 2211-1247, 02/2015, Volume 10, Issue 5, pp. 664 - 673
The primary cilium is an antenna-like, microtubule-based organelle on the surface of most vertebrate cells for receiving extracellular information. Although... 
SPINDLE CHECKPOINT | CENTRIOLE | PLK1 | BUBR1 | BUB1B | CILIOGENESIS | MUTATIONS | IDENTIFICATION | CENTROSOMES | CELL BIOLOGY
Journal Article
Molecular Biology of the Cell, ISSN 1059-1524, 07/2018, Volume 29, Issue 13, pp. 1611 - 1627
A primary cilium is found on most mammalian cells, where it acts as a cellular antenna for the reception of both mechanical and chemical signals. A variety of... 
LOCALIZATION | CENTRIOLE | SUBDISTAL APPENDAGES | CENTROSOME | CILIOGENESIS | TUBULIN | BINDING-PROTEINS | CELL BIOLOGY
Journal Article
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, ISSN 1046-6673, 03/2015, Volume 26, Issue 3, pp. 553 - 564
von Hippel-Lindau (VHL) gene mutations are associated with clear cell renal cell carcinoma (ccRCC). A hallmark of ccRCC is loss of the primary cilium. Loss of... 
PROTEIN | WNT/BETA-CATENIN | SMALL-MOLECULE INHIBITORS | JADE-1 | COMPONENTS | UROLOGY & NEPHROLOGY | PROLIFERATION | CILIOGENESIS | CANCER | EXPRESSION | PVHL
Journal Article
Nature Cell Biology, ISSN 1465-7392, 05/2007, Volume 9, Issue 5, pp. 588 - 595
Defects in the structure or function of the primary cilium, an antennae-like structure whose functional integrity has been linked to the suppression of... 
INACTIVATION | ACTIVATION | PROTEIN | GENE | POLYCYSTIC KIDNEY-DISEASE | STABILITY | GLYCOGEN-SYNTHASE KINASE-3 | CILIOGENESIS | LINDAU TUMOR-SUPPRESSOR | LESIONS | CELL BIOLOGY
Journal Article
Kidney International, ISSN 0085-2538, 08/2019, Volume 96, Issue 2, pp. 320 - 326
Nephronophthisis is an autosomal recessive kidney disease with high genetic heterogeneity. Understanding the functions of the individual genes contributing to... 
cilia | nephronophthisis | centrosome | polycystic kidney disease | CEP164 | APPENDAGES | DOCKING | EARLY STEPS | CENTRIOLE | DISEASE | UROLOGY & NEPHROLOGY | CILIOGENESIS | INHIBITOR
Journal Article
Molecular Biology of the Cell, ISSN 1059-1524, 07/2018, Volume 29, Issue 13, pp. 1628 - 1639
The dynein-2 complex mediates trafficking of ciliary proteins by powering the intraflagellar transport (IFT) machinery containing IFT-A and IFT-B complexes.... 
RETROGRADE INTRAFLAGELLAR TRANSPORT | IFT | GENES | COUPLED RECEPTORS | MECHANISMS | MUTATIONS | CILIOGENESIS | MOTORS | ASPHYXIATING THORACIC DYSTROPHY | B COMPLEX | CELL BIOLOGY
Journal Article
Cilia, ISSN 2046-2530, 12/2015, Volume 4, Issue 1, p. 12
Primary cilia, microtubule-based sensory structures, orchestrate various critical signals during development and tissue homeostasis. In view of the rising... 
Ciliogenesis | Ubiquitin-proteasome system | Primary cilia | Cell cycle | Cancer | Ubiquitin | Health aspects
Journal Article