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ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, ISSN 0066-4804, 05/2017, Volume 61, Issue 5
para-Aminosalicylic acid (PAS) is a second-line antituberculosis drug that has been used to treat multidrug-resistant and extensively drug-resistant... 
MYCOBACTERIUM-TUBERCULOSIS | METHOTREXATE | ELIMINATION | MICROBIOLOGY | GENETIC-VARIANTS | antituberculosis drug | ORGANIC CATION TRANSPORTERS | 22 ANTITUBERCULOSIS DRUGS | drug-drug interactions | THERAPY | PHARMACOKINETICS | membrane transporter | RESISTANCE | PHARMACOLOGY & PHARMACY | ANION TRANSPORTER | Octamer Transcription Factor-1 - antagonists & inhibitors | Organic Anion Transport Protein 1 - metabolism | Proton Pump Inhibitors - pharmacology | Organic Anion Transporters, Sodium-Independent - antagonists & inhibitors | Humans | Naproxen - pharmacology | Organic Cation Transporter 2 - antagonists & inhibitors | Organic Cation Transporter 2 - metabolism | Aminosalicylic Acid - metabolism | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Aminosalicylic Acid - pharmacokinetics | Organic Anion Transporters, Sodium-Independent - metabolism | HEK293 Cells | ATP-Binding Cassette Transporters - metabolism | Biological Transport - drug effects | Cell Line | Organic Anion Transport Protein 1 - antagonists & inhibitors | Ibuprofen - pharmacology | Antitubercular Agents - pharmacology | Probenecid - pharmacology | Quinidine - pharmacology | Verapamil - pharmacology | Antitubercular Agents - pharmacokinetics | Solute Carrier Organic Anion Transporter Family Member 1b1 - antagonists & inhibitors | Solute Carrier Organic Anion Transporter Family Member 1b1 - metabolism | Drug Interactions - physiology | Cimetidine - pharmacology | Aminosalicylic Acid - pharmacology | Biological Transport - physiology | Rifampin - pharmacology | Antitubercular Agents - metabolism | Octamer Transcription Factor-1 - metabolism
Journal Article
Brazilian Journal of Medical and Biological Research, ISSN 0100-879X, 2014, Volume 47, Issue 12, pp. 1068 - 1074
Journal Article
Journal of Gastroenterology and Hepatology, ISSN 0815-9319, 05/2010, Volume 25, Issue 1, pp. S111 - S118
Background and Aims:  We examined the effect of lafutidine, a histamine H2 receptor antagonist with a mucosal protective action mediated by capsaicin‐sensitive... 
mucosal protection | rats | capsaicin‐sensitive afferent neurons | loxoprofen | small intestinal lesion | lafutidine | Lafutidine | Rats | Capsaicin-sensitive afferent neurons | Small intestinal lesion | Mucosal protection | Loxoprofen | Mucin-2 - genetics | Intestinal Mucosa - metabolism | Proton Pump Inhibitors - pharmacology | Intestine, Small - pathology | Capsaicin - pharmacology | Histamine H2 Antagonists - pharmacology | Peptic Ulcer - prevention & control | Acetamides - pharmacology | Male | Phenylpropionates | RNA, Messenger - metabolism | Intestinal Mucosa - drug effects | Peptic Ulcer - microbiology | Piperidines - pharmacology | Anti-Ulcer Agents - pharmacology | Omeprazole - pharmacology | Ampicillin - pharmacology | Disease Models, Animal | Enterobacteriaceae - pathogenicity | Intestine, Small - microbiology | 16,16-Dimethylprostaglandin E2 - pharmacology | Intestinal Mucosa - microbiology | Peptic Ulcer - metabolism | Rats, Sprague-Dawley | Peptic Ulcer - pathology | Animals | Sensory Receptor Cells - drug effects | Nitric Oxide Synthase Type II - genetics | Intestine, Small - drug effects | Cimetidine - pharmacology | Anti-Bacterial Agents - pharmacology | Pyridines - pharmacology | Famotidine - pharmacology | Intestine, Small - metabolism | Peptic Ulcer - chemically induced | Intestinal Mucosa - pathology | Peroxidase - metabolism
Journal Article
Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 2006, Volume 104, Issue 3, pp. 336 - 344
The aim of this study is to investigate the mechanisms of the vasorelaxant effect of the crude extract of (family: Labiatae), also known as “Danshen”, in rat... 
Rat knee joint | Salvia miltiorrhiza | Prostaglandins | CGRP | Nitric oxide | Danshen | rat knee joint | nitric oxide | CHEMISTRY, MEDICINAL | GENE-RELATED PEPTIDE | STIMULATION | NERVES | BLOOD-FLOW | PLANT SCIENCES | INTEGRATIVE & COMPLEMENTARY MEDICINE | INFLAMMATION | ENDOTHELIAL-CELLS | NITRIC-OXIDE | prostaglandins | PHARMACOLOGY & PHARMACY | VASODILATOR | SUBSTANCE-P | CAPSAICIN | Joints - blood supply | Hindlimb | Capsaicin - pharmacology | Drugs, Chinese Herbal - pharmacology | Nitric Oxide Synthase - antagonists & inhibitors | Peptide Fragments - pharmacology | Dose-Response Relationship, Drug | Adrenergic beta-Antagonists - pharmacology | Propranolol - pharmacology | Muscarinic Antagonists - pharmacology | Histamine Antagonists - pharmacology | NG-Nitroarginine Methyl Ester - pharmacology | Vasodilator Agents - pharmacology | Calcitonin Gene-Related Peptide - pharmacology | Receptors, Calcitonin Gene-Related Peptide - antagonists & inhibitors | Rats | Atropine - pharmacology | Rats, Sprague-Dawley | Cyclooxygenase Inhibitors - pharmacology | Joints - innervation | Prostaglandins - physiology | Animals | Pyrilamine - pharmacology | Cimetidine - pharmacology | Flurbiprofen - pharmacology | Histamine receptors | Propranolol hydrochloride | Histamine | Peptides | Dilatation | Vasodilators | Blood vessels | Flurbiprofen
Journal Article
Journal of Pharmacological Sciences, ISSN 1347-8613, 2007, Volume 105, Issue 1, pp. 41 - 47
This study investigated endogenous mediators involved in mosquito allergy-associated itching in mice. An intradermal injection of an extract of mosquito... 
zileuton | itch of mosquito allergy | cutaneous nerve branch | 5-lipoxygense metabolite | dorsal root ganglion neuron | Dorsal root ganglion neuron | Itch of mosquito allergy | Cutaneous nerve branch | Zileuton | PRURITUS | INTRADERMAL SEROTONIN | PAF-ACETHER | ASPIRIN | SCRATCHING BEHAVIOR | LEUKOTRIENE B-4 | HUMAN-SKIN | PHARMACOLOGY & PHARMACY | PLATELET-ACTIVATING-FACTOR | HISTAMINE | ANAPHYLAXIS | Hydroxyurea - analogs & derivatives | Propionates - pharmacology | Betamethasone Valerate - pharmacology | Hydroxyurea - pharmacology | Hypersensitivity - prevention & control | Calcium - metabolism | Ketoprofen - pharmacology | Hypersensitivity - immunology | Male | Quinolines - pharmacology | Dose-Response Relationship, Drug | Hypersensitivity - metabolism | Leukotriene B4 - metabolism | Indoles - pharmacology | Chromones - pharmacology | Lipoxygenase Inhibitors | Pruritus - immunology | NG-Nitroarginine Methyl Ester - pharmacology | Terfenadine - pharmacology | Hydrazines - pharmacology | Arachidonate 5-Lipoxygenase - metabolism | Bridged Bicyclo Compounds, Heterocyclic | Indomethacin - pharmacology | Mice, Inbred ICR | Phospholipid Ethers - pharmacology | Phenylpropionates - pharmacology | Fatty Acids, Unsaturated | Pruritus - metabolism | Animals | Culicidae - immunology | Cimetidine - pharmacology | Pruritus - prevention & control | Mice
Journal Article
American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 12/2009, Volume 297, Issue 6, pp. 1147 - 1162
We tested the novel hypothesis that endogenous adenosine (eADO) activates low-affinity A3 receptors in a model of neurogenic diarrhea in the guinea pig colon.... 
Endogenous adenosine | secretion | Motility | Neurogenic diarrhea | Coordination of motility and secretion | Sonomicrometry | Adenosine A1 receptor | Adenosine A3 receptor | NERVOUS-SYSTEM | PHYSIOLOGY | PRESYNAPTIC INHIBITION | ION-TRANSPORT | sonomicrometry | coordination of motility and secretion | endogenous adenosine | SUBMUCOUS PLEXUS | adenosine A1 receptor | neurogenic diarrhea | INTESTINAL INFLAMMATION | EXPERIMENTAL COLITIS | Cl- secretion | GUINEA-PIG COLON | MYENTERIC NEURONS | TRICHINELLA-SPIRALIS | adenosine A3 receptor | motility | NEUROIMMUNE COMMUNICATION | GASTROENTEROLOGY & HEPATOLOGY | Enteric Nervous System - drug effects | Histamine H2 Antagonists - pharmacology | Colon - drug effects | Receptor, Adenosine A1 - drug effects | Colon - immunology | Colon - innervation | Male | Nicotinic Antagonists - pharmacology | Histamine - metabolism | Muscle, Smooth - drug effects | Piperidines - pharmacology | Neurogenic Bowel - immunology | Chlorides - metabolism | Receptor, Adenosine A3 - metabolism | Neurokinin-1 Receptor Antagonists | Guinea Pigs | Muscle, Smooth - innervation | Enteric Nervous System - metabolism | Receptors, Histamine H2 - drug effects | Adenosine - pharmacology | Colon - metabolism | Muscle Contraction | Adenosine - analogs & derivatives | Dihydropyridines - pharmacology | Theophylline - pharmacology | Intestinal Secretions - metabolism | Histamine Agonists - pharmacology | Theophylline - analogs & derivatives | Gastrointestinal Motility - drug effects | Muscle, Smooth - immunology | Neurogenic Bowel - physiopathology | Xanthines - pharmacology | Neurogenic Bowel - metabolism | Dose-Response Relationship, Drug | Enteric Nervous System - physiopathology | Propane - analogs & derivatives | Mecamylamine - pharmacology | Receptors, Neurokinin-1 - metabolism | Receptors, Histamine H2 - metabolism | Reflex | Receptor, Adenosine A3 - drug effects | Muscle Relaxation | Muscle, Smooth - metabolism | Receptor, Adenosine A1 - metabolism | Animals | Adenosine - metabolism | Cimetidine - pharmacology | Dimaprit - pharmacology | In Vitro Techniques | Neural Inhibition - drug effects | Propane - pharmacology | Histamine | Adenosine | Cell receptors | Neural circuitry | Physiological aspects | Research | Health aspects | Neuroregulation and Motility | Cl− secretion
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 6/2004, Volume 21, Issue 6, pp. 976 - 981
Journal Article
Inflammopharmacology, ISSN 0925-4692, 06/2010, Volume 18, Issue 3, pp. 137 - 145
The aim of the study was to evaluate the antiulcer activity of Linum usitatissimum fixed oil against aspirin-, indomethacin-, ethanol-, reserpine-, serotonin-... 
Antisecretory | Lipoxygenase-inhibitor | Anticholinergic | Antihistaminic | Flaxseed oil | Linseed oil | Serotonin - administration & dosage | Rats, Wistar | Misoprostol - administration & dosage | Ethanol - administration & dosage | Stomach Ulcer - pathology | Indomethacin - administration & dosage | Serotonin - pharmacology | Stomach Ulcer - etiology | Cholinergic Antagonists - pharmacology | Aspirin - administration & dosage | Ileum - drug effects | Reserpine - administration & dosage | Histamine H1 Antagonists - pharmacology | Gastric Mucosa - drug effects | Reserpine - pharmacology | Aspirin - pharmacology | Cimetidine - administration & dosage | Histamine - administration & dosage | Stomach Ulcer - prevention & control | Stomach Ulcer - chemically induced | Guinea Pigs | Histamine - pharmacology | Acetylcholine - pharmacology | Linseed Oil - pharmacology | Rats | Atropine - pharmacology | Linseed Oil - therapeutic use | Pylorus - surgery | Flax - chemistry | Indomethacin - pharmacology | Ethanol - pharmacology | Animals | Gastric Mucosa - secretion | Muscle Contraction - drug effects | Cimetidine - pharmacology | Ligation - adverse effects | Acetylcholine - antagonists & inhibitors | Linseed Oil - administration & dosage | Promethazine - pharmacology | Stress, Psychological - complications | Hydrogen-Ion Concentration | Misoprostol - therapeutic use | Histamine | Aspirin | Corticosteroids | Analysis | Pharmacy | Acetylcholine | Indomethacin | Universities and colleges | Reserpine | Antiulcer drugs
Journal Article
Journal Article
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 11/2001, Volume 134, Issue 5, pp. 951 - 956
Journal Article