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Current Medicinal Chemistry, ISSN 0929-8673, 04/2012, Volume 19, Issue 12, pp. 1846 - 1863
New-generation antidepressants are a heterogeneous class of drugs used in the treatment of depression and related disorders. This review deals with the first... 
Paroxetine | Antidepressants | Fluoxetine | Pharmacological properties | Selective serotonin reuptake inhibitors (SSRIs) | Therapeutic drug monitoring (TDM) | Vilazodone | Fluvoxamine | Sertraline | Chemical-clinical correlations | Citalopram | ELECTRON-CAPTURE DETECTION | POSTTRAUMATIC-STRESS-DISORDER | CHEMISTRY, MEDICINAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | fluvoxamine | TANDEM MASS-SPECTROMETRY | pharmacological properties | OBSESSIVE-COMPULSIVE DISORDER | PERFORMANCE LIQUID-CHROMATOGRAPHY | chemical-clinical correlations | therapeutic drug monitoring (TDM) | fluoxetine | paroxetine | selective serotonin reuptake inhibitors (SSRIs) | PHARMACOLOGY & PHARMACY | MAJOR DEPRESSIVE DISORDER | PLACEBO-CONTROLLED TRIAL | NEW-GENERATION ANTIDEPRESSANTS | citalopram | TRANSPORTER BINDING PROFILE | vilazodone | sertraline | SOLID-PHASE EXTRACTION | Paroxetine - pharmacokinetics | Serotonin Uptake Inhibitors - pharmacokinetics | Fluoxetine - pharmacokinetics | Humans | Citalopram - adverse effects | Depressive Disorder - drug therapy | Paroxetine - therapeutic use | Sertraline - adverse effects | Paroxetine - adverse effects | Benzofurans - pharmacokinetics | Sertraline - pharmacokinetics | Vilazodone Hydrochloride | Sertraline - therapeutic use | Fluoxetine - therapeutic use | Piperazines - pharmacokinetics | Fluoxetine - adverse effects | Fluvoxamine - therapeutic use | Benzofurans - therapeutic use | Serotonin Uptake Inhibitors - therapeutic use | Fluvoxamine - pharmacokinetics | Serotonin Uptake Inhibitors - adverse effects | Piperazines - therapeutic use | Benzofurans - adverse effects | Depressive Disorder - metabolism | Fluvoxamine - adverse effects | Piperazines - adverse effects | Indoles - adverse effects | Citalopram - pharmacokinetics | Citalopram - therapeutic use | Indoles - pharmacokinetics | Indoles - therapeutic use | Drug Monitoring
Journal Article
Journal Article
European Journal of Pharmaceutical Sciences, ISSN 0928-0987, 11/2019, Volume 139, p. 105061
Understanding the influence of ethnicity on drug exposure is key to patient safety and could minimize repetitive clinical studies. This analysis aimed to... 
Ethnicity | Voriconazole | PBPK | CYP2C19 | Lansoprazole | Simcyp | Citalopram | CYP3A4 ACTIVITIES | OMEPRAZOLE METABOLISM | POOR METABOLIZERS | MAIN METABOLITES | LANSOPRAZOLE PHARMACOKINETICS | PROTON-PUMP INHIBITORS | S-MEPHENYTOIN | CYTOCHROME-P450 ENZYMES | PHARMACOLOGY & PHARMACY | HUMAN LIVER
Journal Article
Basic & Clinical Pharmacology & Toxicology, ISSN 1742-7835, 10/2018, Volume 123, Issue 4, pp. 474 - 485
P‐glycoprotein, encoded by ABCB1, is an ATP‐dependent drug efflux pump which exports substances outside the cell. Some studies described connections between... 
SUBSTRATE-SPECIFICITY | TRANSPORTING P-GLYCOPROTEINS | HEALTHY-VOLUNTEERS ASSOCIATION | ACTIVE MOIETY | PHARMACOLOGY & PHARMACY | STATE PLASMA-CONCENTRATIONS | TOXICOLOGY | THERAPEUTIC RESPONSE | MAJOR DEPRESSION | DEFICIENT MICE | CLINICAL-RESPONSE | MULTIDRUG-RESISTANCE GENE | Humans | Middle Aged | Male | Metabolic Clearance Rate | Healthy Volunteers | Young Adult | Biotransformation | Pharmacogenomic Variants | Adult | Female | ATP Binding Cassette Transporter, Subfamily B - genetics | Pharmacogenetics | Administration, Oral | Gene Frequency | Antipsychotic Agents - pharmacokinetics | ATP Binding Cassette Transporter, Subfamily B - metabolism | Polymorphism, Genetic | Spain | Antipsychotic Agents - administration & dosage | Cross-Over Studies | Homozygote | Phenotype | Adolescent | Antidepressive Agents - administration & dosage | Heterozygote | Antidepressive Agents - pharmacokinetics | Genetic aspects | Antipsychotic drugs | Antidepressants | Analysis | Genetic polymorphisms | Haplotypes | Efflux | Neuroleptics | Olanzapine | Change detection | Cytochrome P450 | Central nervous system | Glycoprotein | Glycoproteins | Pharmacology | Aripiprazole | Multivariate analysis | Gene polymorphism | Sertraline | Citalopram | Psychotropic drugs | Plasma levels | Risperidone | Pharmacokinetics | Quetiapine | Polymorphism | Cytochromes P450
Journal Article
American Journal of Psychiatry, ISSN 0002-953X, 05/2004, Volume 161, Issue 5, pp. 826 - 835
Journal Article
Critical Reviews in Toxicology, ISSN 1040-8444, 11/2012, Volume 42, Issue 10, pp. 854 - 876
Clinical outcome following 3,4-methylenedioxymethamphetamine (MDMA) intake ranges from mild entactogenic effects to a life-threatening intoxication. Despite... 
Clinical toxicology | norepinephrine | treatment | ecstasy | cytochrome P450 | intoxication | serotonin | neurotoxicity | receptor | poisoning | CYP2D6 | transporter | metabolism | neurotransmitter | dopamine | CYP2D6 POOR METABOLIZER | IN-VITRO | UPTAKE INHIBITOR CITALOPRAM | INDUCED DOPAMINE RELEASE | TOXICOLOGY | LONG-TERM POTENTIATION | DARK-AGOUTI RATS | SEROTONIN TRANSPORTER GENE | CATECHOL-O-METHYLTRANSFERASE | 5-HT NERVE-ENDINGS | RECEPTOR GENE POLYMORPHISMS | Serotonin Uptake Inhibitors - pharmacokinetics | Body Temperature - drug effects | Humans | N-Methyl-3,4-methylenedioxyamphetamine - blood | Propanolamines - pharmacokinetics | Brain - metabolism | Heart Rate - drug effects | Drug Interactions | Glutathione Transferase - genetics | N-Methyl-3,4-methylenedioxyamphetamine - pharmacology | Models, Animal | Blood Pressure - drug effects | Serotonin Syndrome - physiopathology | Haloperidol - pharmacology | Neurotransmitter Transport Proteins - genetics | Cytochrome P-450 CYP2D6 - genetics | Ketanserin - pharmacology | Haloperidol - pharmacokinetics | Ketanserin - pharmacokinetics | Polymorphism, Genetic | Brain - drug effects | Serotonin Syndrome - chemically induced | Animals | Carbazoles - pharmacokinetics | Receptors, Neurotransmitter - metabolism | Carbazoles - pharmacology | Propanolamines - pharmacology | Serotonin Uptake Inhibitors - pharmacology | N-Methyl-3,4-methylenedioxyamphetamine - pharmacokinetics | Index Medicus
Journal Article
Environmental Toxicology and Chemistry, ISSN 0730-7268, 08/2012, Volume 31, Issue 8, pp. 1831 - 1837
Journal Article
Clinical Drug Investigation, ISSN 1173-2563, 01/2013, Volume 33, Issue 1, pp. 1 - 9
Journal Article
Journal Article