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British Journal of Clinical Pharmacology, ISSN 0306-5251, 09/2013, Volume 76, Issue 3, pp. 455 - 466
AimsThe anticoagulant rivaroxaban is an oral, direct Factor Xa inhibitor for the management of thromboembolic disorders. Metabolism and excretion involve... 
cytochrome | glycoprotein | rivaroxaban | drug interactions | healthy subjects | 450 | P-glycoprotein | Rivaroxaban | Healthy subjects | Cytochrome P450 | Drug interactions | BAY-59-7939 | SAFETY | PREVENTION | PHARMACODYNAMICS | cytochrome P450 | PROTEASE INHIBITORS | IN-VITRO | FACTOR-XA INHIBITOR | ERYTHROMYCIN | PHARMACOLOGY & PHARMACY | LIVER-MICROSOMES | Anticoagulants - administration & dosage | Cytochrome P-450 Enzyme Inhibitors | Erythromycin - pharmacology | Ketoconazole - administration & dosage | Humans | Middle Aged | Cytochrome P-450 Enzyme System - metabolism | Midazolam - administration & dosage | Substrate Specificity | Metabolic Clearance Rate | Thiophenes - administration & dosage | Ketoconazole - pharmacology | Enzyme Inhibitors - administration & dosage | Young Adult | Drug Interactions | Enzyme Inhibitors - pharmacokinetics | Clarithromycin - pharmacokinetics | Clarithromycin - administration & dosage | Adult | Morpholines - administration & dosage | Enzyme Inhibitors - pharmacology | Ketoconazole - pharmacokinetics | Midazolam - pharmacokinetics | Cytochrome P-450 CYP3A - administration & dosage | Erythromycin - administration & dosage | ATP Binding Cassette Transporter, Subfamily B, Member 1 - antagonists & inhibitors | ATP Binding Cassette Transporter, Subfamily B, Member 1 - metabolism | Thiophenes - pharmacokinetics | Erythromycin - pharmacokinetics | Cytochrome P-450 CYP3A - metabolism | Adolescent | Anticoagulants - pharmacokinetics | Morpholines - pharmacokinetics | Clarithromycin - pharmacology | Midazolam - pharmacology | Ketoconazole | Protease inhibitors | Fluconazole | Proteases | Cytochrome P-450 | Dosage and administration | Anticoagulants (Medicine) | Erythromycin | Thromboembolism | Index Medicus
Journal Article
The American Journal of Cardiology, ISSN 0002-9149, 2004, Volume 94, Issue 9, pp. 1140 - 1146
Three-hydroxy-3-methylglutaryl coenzyme-A reductase inhibitors (statins) are first-line treatments for hypercholesterolemia. Although exceedingly well... 
CLARITHROMYCIN | INDUCED RHABDOMYOLYSIS | LOVASTATIN | CARDIAC & CARDIOVASCULAR SYSTEMS | CONCOMITANT USE | ERYTHROMYCIN | FATAL RHABDOMYOLYSIS | ITRACONAZOLE | ROSUVASTATIN | DRUG-INTERACTION | CYCLOSPORINE | Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage | Pyrroles - pharmacokinetics | Cytochrome P-450 Enzyme Inhibitors | Cytochrome P-450 Enzyme System - administration & dosage | Area Under Curve | Heptanoic Acids - pharmacokinetics | Humans | Middle Aged | Mibefradil - pharmacokinetics | Male | Protein Synthesis Inhibitors - administration & dosage | Verapamil - administration & dosage | Dose-Response Relationship, Drug | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacokinetics | Antiprotozoal Agents - pharmacokinetics | Drug Interactions | Itraconazole - pharmacokinetics | Pyrroles - administration & dosage | Clarithromycin - pharmacokinetics | Mibefradil - administration & dosage | Clarithromycin - administration & dosage | Heptanoic Acids - administration & dosage | Adult | Female | Itraconazole - administration & dosage | Drug Therapy, Combination | Double-Blind Method | Simvastatin - administration & dosage | Verapamil - pharmacokinetics | Biomarkers - blood | Simvastatin - pharmacokinetics | Protein Synthesis Inhibitors - pharmacokinetics | Atorvastatin Calcium | Anticholesteremic Agents - pharmacokinetics | Pravastatin - administration & dosage | Anticholesteremic Agents - administration & dosage | Adolescent | Antiprotozoal Agents - administration & dosage | Calcium Channel Blockers - administration & dosage | Creatine Kinase - drug effects | Calcium Channel Blockers - pharmacokinetics | Pravastatin - pharmacokinetics | Index Medicus | Abridged Index Medicus
Journal Article
Gut, ISSN 0017-5749, 09/2016, Volume 65, Issue 9, pp. 1439 - 1446
ObjectiveThe objective of this study was to assess the efficacy, safety and tolerability of vonoprazan, a novel potassium-competitive acid blocker, as a... 
antibiotic therapy | clinical trials | Helicobacter pylori infection | helicobacter pylori - treatment | CLARITHROMYCIN | LANSOPRAZOLE | MULTICENTER | MANAGEMENT | CLINICAL-TRIAL | PHARMACOKINETICS | JAPAN | INFECTION | MONOFUMARATE TAK-438 | GASTROENTEROLOGY & HEPATOLOGY | AMOXICILLIN | Humans | Middle Aged | Helicobacter Infections - complications | Helicobacter pylori - drug effects | Male | Drug Monitoring - methods | Proton Pump Inhibitors - administration & dosage | Pyrroles - administration & dosage | Helicobacter Infections - drug therapy | Clarithromycin - administration & dosage | Metronidazole - adverse effects | Peptic Ulcer - diagnosis | Pyrroles - adverse effects | Adult | Female | Amoxicillin - administration & dosage | Anti-Bacterial Agents - adverse effects | Helicobacter Infections - diagnosis | Lansoprazole - administration & dosage | Proton Pump Inhibitors - adverse effects | Double-Blind Method | Drug Administration Schedule | Clarithromycin - adverse effects | Metronidazole - administration & dosage | Treatment Outcome | Drug Therapy, Combination - methods | Lansoprazole - adverse effects | Sulfonamides - adverse effects | Amoxicillin - adverse effects | Helicobacter pylori - isolation & purification | Anti-Bacterial Agents - administration & dosage | Peptic Ulcer - drug therapy | Breath Tests - methods | Peptic Ulcer - etiology | Sulfonamides - administration & dosage | Usage | Safety and security measures | Research | Helicobacter pylori | Antacids | Index Medicus | Abridged Index Medicus | Helicobacter Pylori | HELICOBACTER PYLORI - TREATMENT | CLINICAL TRIALS | 1506 | ANTIBIOTIC THERAPY | HELICOBACTER PYLORI INFECTION
Journal Article
Lancet, The, ISSN 0140-6736, 2016, Volume 388, Issue 10058, pp. 2355 - 2365
Summary Background Whether concomitant therapy is superior to bismuth quadruple therapy or 14-day triple therapy for the first-line treatment of Helicobacter... 
Internal Medicine | CLARITHROMYCIN | ESOMEPRAZOLE | MEDICINE, GENERAL & INTERNAL | METAANALYSIS | EFFICACY | GASTRIC-CANCER | RESISTANCE | SEQUENTIAL THERAPY | INFECTION | ERADICATION | METRONIDAZOLE | Humans | Middle Aged | Helicobacter pylori - drug effects | Male | Antacids - therapeutic use | Anti-Bacterial Agents - therapeutic use | Proton Pump Inhibitors - administration & dosage | Metronidazole - therapeutic use | Helicobacter Infections - drug therapy | Clarithromycin - administration & dosage | Organometallic Compounds - therapeutic use | Female | Urea - metabolism | Amoxicillin - administration & dosage | Lansoprazole - administration & dosage | Drug Administration Schedule | Metronidazole - administration & dosage | Breath Tests | Tetracycline - therapeutic use | Clarithromycin - therapeutic use | Proton Pump Inhibitors - therapeutic use | Amoxicillin - therapeutic use | Taiwan | Drug Therapy, Combination - statistics & numerical data | Lansoprazole - therapeutic use | Antacids - administration & dosage | Anti-Bacterial Agents - administration & dosage | Tetracycline - administration & dosage | Organometallic Compounds - administration & dosage | Clinical trials | Medical colleges | Helicobacter infections | Care and treatment | Helicobacter pylori | Antiulcer drugs | Analysis | Bacteria | Bacterial infections | Antibiotics | Drug resistance | Drug therapy | Index Medicus | Abridged Index Medicus
Journal Article
Lancet, The, ISSN 0140-6736, 2011, Volume 377, Issue 9769, pp. 905 - 913
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 03/2016, Volume 374, Issue 13, pp. 1209 - 1220
Journal Article
European Journal of Internal Medicine, ISSN 0953-6205, 2016, Volume 32, pp. 84 - 90
Abstract Background Currently only a few studies compare sequential and concomitant non-bismuth Helicobacter pylori therapies referring to high antibiotic... 
Internal Medicine | H. pylori treatment | Sequential treatment | First line | Concomitant treatment | Metronidazole resistance | Clarithromycin resistance | 14-DAY TRIPLE | 1ST-LINE TREATMENT | MULTICENTER | METAANALYSIS | REGIMEN | STANDARD TRIPLE THERAPY | RATES | MEDICINE, GENERAL & INTERNAL | INFECTION | HYBRID THERAPY | DURATION | Esomeprazole - administration & dosage | Humans | Middle Aged | Carbon Isotopes | Drug Resistance, Bacterial | Male | Helicobacter Infections - pathology | Helicobacter pylori | Peptic Ulcer - microbiology | Proton Pump Inhibitors - administration & dosage | Helicobacter Infections - drug therapy | Clarithromycin - administration & dosage | Adult | Female | Helicobacter Infections - metabolism | Urea - metabolism | Amoxicillin - administration & dosage | Drug Therapy, Combination | Dyspepsia - drug therapy | Metronidazole - administration & dosage | Breath Tests | Dyspepsia - microbiology | Pyloric Antrum - pathology | Biopsy | Aged | Anti-Bacterial Agents - administration & dosage | Peptic Ulcer - drug therapy | Clinical trials | Drug resistance in microorganisms | Clarithromycin | Index Medicus | Helicobacter Infections/drug therapy | Peptic Ulcer/drug therapy | Proton Pump Inhibitors/administration & dosage | Helicobacter Infections/pathology | Peptic Ulcer/microbiology | Tissues and Organs | Life Sciences | Esomeprazole/administration & dosage | Hépatology and Gastroenterology | Pyloric Antrum/pathology | Anti-Bacterial Agents/administration & dosage | Dyspepsia/microbiology | Helicobacter Infections/metabolism | Bacteriology | Clarithromycin/administration & dosage | Urea/metabolism | Metronidazole/administration & dosage | Microbiology and Parasitology | Human health and pathology | Amoxicillin/administration & dosage | Dyspepsia/drug therapy
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 01/2015, Volume 191, Issue 1, pp. 96 - 103
Journal Article
Lancet, The, ISSN 0140-6736, 2013, Volume 381, Issue 9862, pp. 205 - 213
Journal Article
Digestive Diseases and Sciences, ISSN 0163-2116, 2/2015, Volume 60, Issue 2, pp. 458 - 464
Helicobacter pylori eradication is a challenge in penicillin allergy.To assess the efficacy and safety of first-line and rescue treatments in patients allergic... 
Biochemistry, general | Levofloxacin | Allergy | Quinolone | Oncology | Eradication | Allergic | Transplant Surgery | Medicine & Public Health | Helicobacter pylori | Hepatology | Gastroenterology | Penicillin | Bismuth | CLARITHROMYCIN | ANTIBIOTIC-RESISTANCE | QUADRUPLE THERAPY | PROTON PUMP INHIBITOR | TRIPLE THERAPY | INFECTION | METRONIDAZOLE | GASTROENTEROLOGY & HEPATOLOGY | TREATMENT FAILURE | Predictive Value of Tests | Bismuth - administration & dosage | Prospective Studies | Humans | Middle Aged | Salvage Therapy | Helicobacter pylori - drug effects | Male | Rifabutin - administration & dosage | Proton Pump Inhibitors - administration & dosage | Time Factors | Antacids - adverse effects | Helicobacter Infections - drug therapy | Clarithromycin - administration & dosage | Penicillins - adverse effects | Female | Anti-Bacterial Agents - adverse effects | Helicobacter Infections - diagnosis | Drug Therapy, Combination | Levofloxacin - administration & dosage | Drug Hypersensitivity - etiology | Proton Pump Inhibitors - adverse effects | Drug Administration Schedule | Metronidazole - administration & dosage | Omeprazole - administration & dosage | Breath Tests | Treatment Outcome | Spain | Medication Adherence | Helicobacter pylori - isolation & purification | Antacids - administration & dosage | Anti-Bacterial Agents - administration & dosage | Tetracycline - administration & dosage | Helicobacter Infections - microbiology | Urea | Antibacterial agents | Allergic reaction | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article