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Journal Article
Journal Article
Inflammation Research, ISSN 1023-3830, 9/2011, Volume 60, Issue 9, pp. 869 - 878
There are many reports suggesting a relationship between the tonsillar autoimmune response and the pathogenesis of IgA nephropathy (IgAN). Hyperproduction of... 
Allergology | Neurology | Palatine tonsils | Biomedicine | Immunology | IgA nephropathy | Dermatology | Rheumatology | Activation-induced cytidine deaminase | Class switching recombination | Pharmacology/Toxicology | Germline transcript | CYTIDINE DEAMINASE AID | SOMATIC HYPERMUTATION | PERIPHERAL-BLOOD | IMMUNOLOGY | DNA DEAMINATION | CELL BIOLOGY | B-CELLS | HAEMOPHILUS-PARAINFLUENZAE ANTIGENS | GERMINAL-CENTERS | DEPENDENT ANTIBODY-RESPONSES | IN-SITU | PRIMARY IMMUNE-RESPONSE | Humans | Middle Aged | Glomerulonephritis, IGA - immunology | Immunoglobulin A - genetics | Glomerulonephritis, IGA - genetics | Male | Lipopolysaccharides - immunology | Palatine Tonsil - immunology | Palatine Tonsil - cytology | Young Adult | Leukocytes, Mononuclear - physiology | Leukocytes, Mononuclear - immunology | Palatine Tonsil - microbiology | Adult | Female | Leukocytes, Mononuclear - drug effects | Tonsillitis - immunology | Streptococcus - immunology | Cytidine Deaminase - genetics | Cells, Cultured | Palatine Tonsil - pathology | Cytidine Deaminase - metabolism | Immunoglobulin A - immunology | Adolescent | Lipopolysaccharides - pharmacology | Leukocytes, Mononuclear - cytology | Cell Proliferation - drug effects | Immunoglobulin Class Switching - genetics | Autoimmunity | Care and treatment | Messenger RNA | Lymphocytes | Genetic research | Kidney diseases | Immunoglobulin A | Mitogens | Enzyme-linked immunosorbent assay
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 02/2002, Volume 195, Issue 3, pp. 367 - 373
B cells from mice deficient in mismatch repair (MMR) proteins show decreased ability to undergo class switch recombination in vitro and in vivo. The deficit is... 
DNA recombination | DNA repair | Mismatch repair | Splenic B cells | Antibody heavy chain isotypes | MEDICINE, RESEARCH & EXPERIMENTAL | COMPLEX | SOMATIC HYPERMUTATION | mismatch repair | DOUBLE-STRAND BREAKS | splenic B cells | antibody heavy chain isotypes | IMMUNOLOGY | SACCHAROMYCES-CEREVISIAE | MSH2-DEFICIENT MICE | B-CELLS | DNA | DEFICIENT | HETERODIMER | MUTATIONS | MutL Protein Homolog 1 | Neoplasm Proteins - immunology | Molecular Sequence Data | Base Pair Mismatch | DNA Repair - genetics | Adenosine Triphosphatases - immunology | DNA-Binding Proteins - deficiency | Recombination, Genetic | Base Sequence | Proto-Oncogene Proteins - immunology | Mismatch Repair Endonuclease PMS2 | Neoplasm Proteins - genetics | Immunoglobulin Class Switching | Carrier Proteins | Adenosine Triphosphatases - deficiency | DNA-Binding Proteins - immunology | Mice, Inbred C57BL | Proto-Oncogene Proteins - genetics | MutS Homolog 2 Protein | Proto-Oncogene Proteins - deficiency | DNA Repair Enzymes | DNA-Binding Proteins - genetics | Sequence Homology, Nucleic Acid | Mice, Knockout | Nuclear Proteins | DNA - genetics | Adaptor Proteins, Signal Transducing | Animals | B-Lymphocytes - immunology | DNA Repair - immunology | Adenosine Triphosphatases - genetics | Mice | Neoplasm Proteins - deficiency | In Vitro Techniques | Brief Definitive Report
Journal Article
The Journal of Immunology, ISSN 0022-1767, 05/2005, Volume 174, Issue 10, pp. 6176 - 6183
Except for the expression of IgM and IgD, DNA recombination is constantly needed for the expression of other Ig classes and subclasses. The predominant path of... 
ALLELIC EXCLUSION | CONTROL REGION | REPLICATION | TRANSLOCATIONS | CIRCULAR DNA | TRANSCRIPTION | OCCURS | HEAVY-CHAIN LOCUS | MICE | IMMUNOLOGY | DELETION | Immunoglobulin alpha-Chains - genetics | Immunoglobulin gamma-Chains - genetics | Immunoglobulin A - biosynthesis | Gene Rearrangement, B-Lymphocyte, Light Chain - genetics | Immunoglobulin A - genetics | Male | Cell Differentiation - genetics | Immunoglobulin Constant Regions - genetics | Immunoglobulin J-Chains - genetics | Mice, Mutant Strains | Recombination, Genetic | Female | Plasma Cells - metabolism | B-Lymphocytes - metabolism | Immunoglobulin M - genetics | Mice, Inbred C57BL | Cells, Cultured | Exons - genetics | Cell Differentiation - immunology | Homozygote | Microscopy, Confocal | Immunoglobulin kappa-Chains - genetics | Animals | B-Lymphocytes - immunology | Alleles | Immunoglobulin A - blood | Immunoglobulin Variable Region - genetics | Mice | Mice, Inbred BALB C | Mutagenesis, Insertional | Gene Rearrangement, B-Lymphocyte, Heavy Chain - genetics | Immunoglobulin Class Switching - genetics | Genetic Carrier Screening | Immunoglobulin M - biosynthesis | Plasma Cells - immunology | Immunoglobulin M | Exons | Immunoglobulin kappa-Chains | B-Lymphocytes | Immunoglobulin A | Heterozygote Detection | Life Sciences | Immunology | Gene Rearrangement, B-Lymphocyte, Light Chain | Cell Differentiation | Immunoglobulin Variable Region | Plasma Cells | Immunoglobulin gamma-Chains | Immunoglobulin Class Switching | Immunoglobulin J-Chains | Gene Rearrangement, B-Lymphocyte, Heavy Chain | Immunoglobulin Constant Regions | Immunoglobulin alpha-Chains
Journal Article
Cell Reports, ISSN 2211-1247, 06/2013, Volume 3, Issue 6, pp. 1824 - 1831