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Journal Article
European Journal of Pharmaceutical Sciences, ISSN 0928-0987, 10/2016, Volume 94, pp. 59 - 71
Develop a minimal mechanistic model based on in vitro–in vivo extrapolation (IVIVE) principles to predict extent of passive tubular reabsorption. Assess the... 
Renal excretion clearance | Tubular reabsorption | In vitro–in vivo extrapolation | ANTIPYRINE | PERMEABILITY | TRANSPORTERS | URINE FLOW | GLUCURONIDATION | GLOMERULAR-FILTRATION-RATE | IN-VITRO | MATHEMATICAL-MODEL | PHARMACOKINETICS | PHARMACOLOGY & PHARMACY | In vitro-in vivo extrapolation | LIPOPHILICITY | Renal Elimination - physiology | Kidney Tubules - drug effects | Humans | Renal Elimination - drug effects | Glomerular Filtration Rate - physiology | Metabolic Clearance Rate - physiology | Glomerular Filtration Rate - drug effects | Pharmaceutical Preparations - metabolism | Models, Biological | Metabolic Clearance Rate - drug effects | Clinical Trials as Topic - methods | Kidney Tubules - metabolism | Pharmaceutical Preparations - administration & dosage | Analysis | Permeability | PT, proximal tubule | LogD, octanol-buffer distribution coefficient | P-gp, P-glycoprotein | CLR, filt, renal filtration clearance | OCT, organic cation transporter | DT, distal tubule | OCTN, organic cation | GFR, glomerular filtration rate | gmfe, geometric mean fold error | OAT, organic anion transporter | OATP, organic anion-transporting peptides | CD, collecting duct | Freab, fraction of the drug reabsorbed in the renal tubule | TSA, tubular surface area | CLR,sec, renal secretion clearance | AUC, area under the plasma concentration-time profile | CLR, int,reab, intrinsic permeability clearance in renal tubule | fu,p, fraction of drug unbound in plasma | l-carnitine transporter | PBPK, physiologically-based pharmacokinetic | Freab’, intermediate model parameter, representing the fraction of the equilibrium reached between unbound drug concentration in the plasma and urine | Cp, plasma concentration | Papp, apparent permeability | RMSE, root mean squared error | TFR, tubular flow rate | BCRP, breast cancer resistance protein | IVIVE, in vitro–in vivo extrapolation | LoH, loop of Henle | MATE, multidrug and toxin extrusion protein | MRP, multidrug resistance protein | CLR, renal excretion clearance
Journal Article
Journal Article
2017, 1, ISBN 9781859466315, xx, 234 pages
The problem of creating affordable, adequate housing for a growing population is not a new one. This book, aimed at anyone with a professional or personal... 
Housing | History | Professional Practice | Sustainable Architecture | Urban Design | Dwellings
Book
2013, ISBN 0691157294, xv, 269
Under the New Jersey State Constitution as interpreted by the State Supreme Court in 1975 and 1983, municipalities are required to use their zoning authority... 
Zoning, Exclusionary | Housing | Low-income housing | Social mobility | Housing & Urban Development | Urban | Law | Sociology | United States | Poverty & Homelessness | General | State & Local | History | Social Science | Middle Atlantic (Dc, De, Md, Nj, Ny, Pa) | Political Science | Mount Laurel (Township) | New Jersey | SOCIAL SCIENCE
Book
Journal Article
Journal Article