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1986, Monographs in epidemiology and biostatistics, ISBN 0195035682, Volume 8, xxvi, 469 p. --
This book starts with a general discussion of clinical trials. It goes on to describe the activities of a typical study, comparing single center and... 
Clinical Trials | public health and epidemiology | Quality assurance | Execution | Sample size estimates | Costs factors | Multicenter trials | Single center trials | Typical study | Treatment masking | Design principles | Follow-up
Book
Statistics in Medicine, ISSN 0277-6715, 11/2018, Volume 37, Issue 25, pp. 3557 - 3572
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 04/2016, Volume 34, Issue 12, pp. 1402 - 1418
Journal Article
Trends in Pharmacological Sciences, ISSN 0165-6147, 08/2019, Volume 40, Issue 8, pp. 577 - 591
Clinical trials consume the latter half of the 10 to 15 year, 1.5–2.0 billion USD, development cycle for bringing a single new drug to market. Hence, a failed... 
patient recruitment | cohort selection | machine learning | trial design | patient monitoring | artificial intelligence | DEEP | SUCCESS | BIG DATA | VALIDATION | SYSTEMS | RISK | PHARMACOLOGY & PHARMACY | IBM WATSON | SEIZURE PREDICTION | Medicine, Experimental | Clinical trials | Medical research | Artificial intelligence | Machine learning
Journal Article
American Heart Journal, ISSN 0002-8703, 2017, Volume 187, pp. 182 - 190
Background Patients with prior vascular disease remain at high risk of cardiovascular events despite intensive statin-based treatment. Inhibition of... 
Cardiovascular | LDL CHOLESTEROL | CARDIAC & CARDIOVASCULAR SYSTEMS | ESTER TRANSFER PROTEIN | STATIN THERAPY | HIGH-RISK | FOLLOW-UP | HDL CHOLESTEROL | OUTCOMES | CORONARY-HEART-DISEASE | INHIBITOR ANACETRAPIB | 11-YEAR MORTALITY | Double-Blind Method | Cholesterol, HDL - drug effects | Humans | Middle Aged | Cholesterol, LDL - drug effects | Male | Oxazolidinones - adverse effects | Anticholesteremic Agents - adverse effects | Oxazolidinones - therapeutic use | Coronary Disease - prevention & control | Anticholesteremic Agents - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Intention to Treat Analysis | Cholesterol, HDL - blood | Cholesterol, LDL - blood | Female | Aged | Drug Therapy, Combination | Research Design | Atorvastatin Calcium - therapeutic use | Clinical trials | Medicine, Experimental | Blood circulation disorders | Medical research | Low density lipoproteins | Cardiovascular agents | Coronary heart disease | Epidemiology | Blood cholesterol | Coronary artery bypass | Diabetes | Trans fatty acids | Statins | Myocardial infarction | Lipoproteins (low density) | Evaluation | Diabetes mellitus | Health risks | Lipids | Cardiovascular disease | Low density lipoprotein | Coronary artery disease | Cholesterol | Cholesteryl ester transfer protein | Recruitment | Motivation | Safety engineering | Arteriosclerosis | Atorvastatin | Cardiovascular diseases | Health risk assessment | Heart diseases | Lipoproteins (high density) | Trial Design
Journal Article
CURRENT OPINION IN NEUROLOGY, ISSN 1350-7540, 06/2019, Volume 32, Issue 3, pp. 358 - 364
Purpose of review Recent years have seen the approval of more than 15 disease-modifying drugs for multiple sclerosis (MS), mainly for its relapsing-remitting... 
BRAIN ATROPHY | PLACEBO | MULTICENTER | multiple sclerosis | PROGRESSIVE MS | MAGNETIZATION-TRANSFER | clinical trial design | NEUROSCIENCES | CLINICAL NEUROLOGY | OUTCOME MEASURES | RECOMMENDATIONS | DOUBLE-BLIND | DISABILITY | INTERFERON BETA-1B | Multiple sclerosis | Analysis | Clinical trials | Dosage and administration | Research | Drug therapy | Neuroprotective agents
Journal Article
American Heart Journal, ISSN 0002-8703, 2010, Volume 159, Issue 3, pp. 331 - 339
Atrial fibrillation (AF) is associated with increased risk of stroke that can be attenuated with vitamin K antagonists (VKAs). Vitamin K antagonist use is... 
Cardiovascular | XIMELAGATRAN | CARDIAC & CARDIOVASCULAR SYSTEMS | ANTICOAGULATION CONTROL | WARFARIN | ANTITHROMBOTIC THERAPY | PREVENTION | RISK | HEPARIN | ASPIRIN | FACTOR XA INHIBITOR | ANTIPLATELET THERAPY | Pyrazoles - therapeutic use | Factor Xa Inhibitors | Follow-Up Studies | Humans | Middle Aged | Warfarin - adverse effects | Warfarin - therapeutic use | Young Adult | Fibrinolytic Agents - adverse effects | Thromboembolism - prevention & control | Fibrinolytic Agents - therapeutic use | Adult | Pyrazoles - adverse effects | Stroke - prevention & control | Atrial Fibrillation - drug therapy | Anticoagulants - therapeutic use | Treatment Outcome | Anticoagulants - adverse effects | International Normalized Ratio | Adolescent | Aged | Pyridones - therapeutic use | Hemorrhage - chemically induced | Research Design | Pyridones - adverse effects | Stroke (Disease) | Clinical trials | Medical colleges | Warfarin | Atrial fibrillation | Risk factors | Health care | Anticoagulants | Cardiac arrhythmia | Stroke | Mortality | Thrombosis | Joint replacement surgery | Disease prevention | Blood platelets | Biomarkers | Blood pressure | Diabetes | Drug therapy | Drug dosages | Pyrazoles | Pyridones | Factor Xa | Fibrinolytic Agents | Hemorrhage | Life Sciences | Thromboembolism | Atrial Fibrillation | Medical and Health Sciences | MEDICINE | Medicin och hälsovetenskap | MEDICIN
Journal Article