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Nature Genetics, ISSN 1061-4036, 07/2016, Volume 48, Issue 7, pp. 768 - 776
...), yet very few studies have analyzed recurrent GBM and patient cohorts are limited in size (5-7). The evolution of tumor cells under therapy can be viewed... 
GENE FUSIONS | TGF-BETA | CANCER GENOMICS | LANDSCAPE | GLIOMA | GENETICS & HEREDITY | GENOMIC ALTERATIONS | MSH6 MUTATIONS | SEQUENCING DATA | BRAIN-TUMORS | TEMOZOLOMIDE | Cell Proliferation | Dacarbazine - therapeutic use | Genomics | Humans | Brain Neoplasms - pathology | DNA Repair Enzymes - genetics | Gene Expression Regulation, Neoplastic | Transcriptome | Neoplasm Recurrence, Local - drug therapy | Clonal Evolution - genetics | Neoplasm Recurrence, Local - pathology | Neoplasm Grading | Glioblastoma - genetics | Tumor Suppressor Proteins - genetics | Dacarbazine - analogs & derivatives | Brain Neoplasms - genetics | Isocitrate Dehydrogenase - genetics | Survival Rate | Brain Neoplasms - drug therapy | Mutation - genetics | Antineoplastic Agents, Alkylating - therapeutic use | Latent TGF-beta Binding Proteins - genetics | DNA Modification Methylases - genetics | Transforming Growth Factor beta - genetics | Glioblastoma - pathology | Neoplasm Recurrence, Local - genetics | Biomarkers, Tumor - genetics | Temozolomide | Glioblastoma - drug therapy | Longitudinal Studies | Molecular targeted therapy | Care and treatment | Gene mutations | Development and progression | Genetic aspects | Genetic transcription | Glioblastoma multiforme | Health aspects | Methods | Brain cancer | Genomes | Gene expression | Cancer therapies | Studies | Archives & records | DNA methylation | Mathematical models | Mutation | Deoxyribonucleic acid--DNA | Tumors | Cancer
Journal Article
Science, ISSN 0036-8075, 1/2014, Volume 343, Issue 6167, pp. 189 - 193
...; this suggests that recurrent tumors are often seeded by cells derived from the initial tumor at a very early stage of their evolution... 
Geography | Glioma | REPORTS | Medical genetics | Evolution | Evolutionary genetics | Genomes | Genetic mutation | Genetic heterogeneity | Cancer | Tumors | RETINOBLASTOMA | IDH1 MUTATIONS | MULTIDISCIPLINARY SCIENCES | INTRATUMOR HETEROGENEITY | GROWTH | CLONAL EVOLUTION | MSH6 MUTATIONS | IDENTIFICATION | HUMAN CANCER | HUMAN-MALIGNANT GLIOMAS | TEMOZOLOMIDE | Dacarbazine - adverse effects | Dacarbazine - therapeutic use | Humans | Brain Neoplasms - pathology | Neoplasm Recurrence, Local - drug therapy | X-linked Nuclear Protein | Mutagenesis - drug effects | Proto-Oncogene Proteins c-akt - genetics | Tumor Suppressor Protein p53 - genetics | Glioma - genetics | Neoplasm Grading | TOR Serine-Threonine Kinases - genetics | DNA Mutational Analysis | Glioma - pathology | Dacarbazine - analogs & derivatives | Nuclear Proteins - genetics | DNA Helicases - genetics | Brain Neoplasms - genetics | Transcription Factors - genetics | Brain Neoplasms - drug therapy | Antineoplastic Agents, Alkylating - therapeutic use | Brain - drug effects | Proto-Oncogene Proteins B-raf - genetics | Neoplasm Recurrence, Local - chemically induced | Brain - pathology | Neoplasm Recurrence, Local - genetics | Antineoplastic Agents, Alkylating - adverse effects | Glioma - drug therapy | Care and treatment | Gene mutations | Gliomas | Physiological aspects | Genetic aspects | Research | Methods | Studies | Brain surgery | Mutagenesis | Brain cancer | Clinical outcomes | Index Medicus
Journal Article
Journal Article
Journal Article
Nature Medicine, ISSN 1078-8956, 03/2016, Volume 22, Issue 3, pp. 298 - 305
Journal Article
Nature Reviews Genetics, ISSN 1471-0056, 11/2012, Volume 13, Issue 11, pp. 795 - 806
Journal Article
Nature, ISSN 0028-0836, 08/2018, Volume 560, Issue 7718, pp. 325 - 330
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2013, Volume 110, Issue 45, pp. 18250 - 18255
Journal Article