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Immunity, ISSN 1074-7613, 05/2015, Volume 42, Issue 5, pp. 929 - 941
It has long been thought that clonal deletion efficiently removes almost all self-specific T cells from the peripheral repertoire. We found that self-peptide... 
CD8-Positive T-Lymphocytes - cytology | Clonal Deletion | Animals | Flow Cytometry | Antigenic Variation | Self Tolerance - immunology | Humans | Female | Male | Mice | CD8-Positive T-Lymphocytes - immunology | Receptors, Antigen, T-Cell, alpha-beta - genetics | Index Medicus
Journal Article
The Journal of Pathology, ISSN 0022-3417, 08/2019, Volume 248, Issue 4, pp. 396 - 408
Journal Article
European Journal of Immunology, ISSN 0014-2980, 12/2018, Volume 48, Issue 12, pp. 2055 - 2067
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 02/2013, Volume 210, Issue 2, pp. 269 - 285
Acquisition of self-tolerance in the thymus requires T cells to discriminate strong versus weak T cell receptor binding by self-peptide-MHC complexes. We find... 
DEVELOPING THYMOCYTES | MEDICINE, RESEARCH & EXPERIMENTAL | TISSUE-RESTRICTED ANTIGENS | SELF-PEPTIDE | RECEPTOR TRANSGENIC MICE | IN-VIVO | BIM | NEGATIVE SELECTION | C-MYC | CLONAL DELETION | IMMUNOLOGY | EXPRESSION | Autoimmunity | Cell Proliferation | NF-kappa B - immunology | Proto-Oncogene Proteins c-rel - metabolism | Proto-Oncogene Proteins - biosynthesis | Proto-Oncogene Proteins c-rel - immunology | CARD Signaling Adaptor Proteins - genetics | CD4-Positive T-Lymphocytes - immunology | Membrane Proteins - deficiency | CARD Signaling Adaptor Proteins - metabolism | Bcl-2-Like Protein 11 | Receptors, CCR7 - metabolism | Apoptosis Regulatory Proteins - deficiency | Programmed Cell Death 1 Receptor - biosynthesis | Proto-Oncogene Proteins - immunology | Apoptosis Regulatory Proteins - genetics | Transcription Factors - immunology | Apoptosis Regulatory Proteins - biosynthesis | CARD Signaling Adaptor Proteins - immunology | Apoptosis Regulatory Proteins - immunology | DNA-Binding Proteins - immunology | Lymphocyte Activation | Membrane Proteins - genetics | CD4-Positive T-Lymphocytes - cytology | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Self Tolerance | Membrane Proteins - immunology | Mice, Transgenic | Proto-Oncogene Proteins - genetics | Transcription Factors - biosynthesis | Proto-Oncogene Proteins - deficiency | Clonal Deletion - immunology | Mice, Knockout | Membrane Proteins - biosynthesis | Animals | Apoptosis - immunology | Proto-Oncogene Proteins c-rel - genetics | NF-kappa B - biosynthesis | Mice | Mutation | Programmed Cell Death 1 Receptor - immunology | DNA-Binding Proteins - biosynthesis | Index Medicus | 309
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 6510 - 11
African swine fever (ASF) was introduced into the Eastern European Union in 2014 and led to considerable mortality among wild boar. In contrast, unexpected... 
SWINE-FEVER VIRUS | CATALYTIC SUBUNIT | PARENTAL VIRUS | MULTIDISCIPLINARY SCIENCES | CAUCASUS ISOLATE | GENES | EUROPEAN WILD BOARS | ISOLATE HARBORING DELETIONS | MULTIGENE FAMILY-360 | INFECTED-CELLS | DOMESTIC PIGS | Hogs | Phenotypes | African swine fever | Clonal deletion | Virulence | Base pairs | Genomes | Gene deletion | Strains (organisms) | Fever
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 08/2017, Volume 214, Issue 8, pp. 2257 - 2269
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 948 - 9
Tumours have developed strategies to interfere with most steps required for anti-tumour immune responses. Although many populations contribute to anti-tumour... 
ACTIVATION | MELANOMA | DENDRITIC CELLS | INFILTRATING LYMPHOCYTES | MULTIDISCIPLINARY SCIENCES | STEADY-STATE | PD-1 | EXPRESSION | PROGRESSION | EXHAUSTION | CROSS-PRESENTATION | Antigens | Immune response | CD8 antigen | Crosstalk | Cytotoxicity | Lymphocytes T | FasL protein | Immune checkpoint | Clonal deletion | Lymphocytes | Stromal cells | Fibroblasts | Deletion | Tumors | Cancer | Index Medicus
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2011, Volume 108, Issue 43, pp. 17815 - 17820
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2008, Volume 3, Issue 3, pp. e1709 - e1709
Prader-Willi syndrome (PWS) is the leading genetic cause of obesity. After initial severe hypotonia, PWS children become hyperphagic and morbidly obese, if... 
MULTIDISCIPLINARY SCIENCES | Blotting, Southern | Growth Disorders - pathology | Male | RNA, Messenger - metabolism | Immunoenzyme Techniques | Behavior, Animal | Gene Deletion | Prader-Willi Syndrome - genetics | Female | Integrases - metabolism | Disease Models, Animal | Animals, Newborn | Enzyme-Linked Immunosorbent Assay | Mice, Inbred C57BL | RNA, Messenger - genetics | Oxygen Consumption | Reverse Transcriptase Polymerase Chain Reaction | RNA, Small Nucleolar - genetics | Hyperphagia - genetics | Hyperphagia - pathology | Ghrelin - blood | Animals | Energy Metabolism | Prader-Willi Syndrome - pathology | Mice | Growth Disorders - genetics | Insulin-Like Growth Factor I - metabolism | Type 2 diabetes | Somatotropin | RNA | Growth | Hyperphagia | Pediatrics | Anorexia | Target recognition | Liver | Cognitive ability | Nervous system | Biochemistry | Proteins | Fertility | Genetics | Anxiety | Chromosomes | Obesity | Body temperature | Metabolism | Mammals | Gene expression | Hypogonadism | Energy balance | Ribonucleic acids | Weight reduction | Growth hormone | Non-coding RNA | Insulin-like growth factor I | Genes | Homeostasis | Genomes | mRNA | Insulin-like growth factors | Defects | High fat diet | Nucleoli | Hypotonia | Energy | Clonal deletion | Ghrelin | Rodents | Deletion | Children | Trends | Age | Translocation | Prader-Willi syndrome | Secretion | Feeding | Life span | Motor skill learning | Pituitary | Index Medicus
Journal Article