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Rheumatology, ISSN 1462-0324, 10/2008, Volume 47, Issue 10, pp. 1588 - 1589
Journal Article
by Chen, LY and Wu, FF and Yuan, SJ and Feng, B
FISH & SHELLFISH IMMUNOLOGY, ISSN 1050-4648, 12/2016, Volume 59, pp. 233 - 240
Clq is the target recognition protein of the classical complement pathway and a major connecting, link between innate and acquired immunity. C1q and the... 
IMMUNE-RESPONSE | COMPLEMENT | C1Q | SEA LAMPREY | Clq | C1Q-DOMAIN-CONTAINING PROTEINS | IMMUNOLOGY | FAMILY | FISHERIES | EVOLUTION | Clq/TNF-Related protein (CTRP) | MARINE & FRESHWATER BIOLOGY | VETERINARY SCIENCES | Lamprey | VARIABLE LYMPHOCYTE RECEPTORS | BRAIN | INSIGHTS
Journal Article
Leukemia & Lymphoma, ISSN 1042-8194, 06/2019, Volume 60, Issue 7, pp. 1812 - 1818
Multiple myeloma (MM) patients are immunodeficient. Complement C1q is an important cofactor of both nonspecific and humoral immunity, and it participates in... 
immunodeficiency | Multiple myeloma | complement C1q | ACTIVATION | ONCOLOGY | IMMUNOTHERAPY | DEPOSITION | CLQ | HEMATOLOGY
Journal Article
Developmental and Comparative Immunology, ISSN 0145-305X, 02/2020, Volume 103, p. 103532
Complement component 1q (C1q), together with C1r and C1s to form C1, recognize and bind immune complex to initiate the classical complement pathway. In this... 
Immunoglobulin (Ig) | Hemolysis | C1q-Ig interaction | Complement component 1q (C1q) | Xenopus laevis | SYSTEM | ACTIVATION | 1ST COMPONENT | SUBCOMPONENT | CLQ | 4TH COMPONENT | IMMUNOLOGY | FISHERIES | ZOOLOGY | PATHWAY | PURIFICATION | BINDING-SITES | GLOBULAR DOMAIN
Journal Article
Analytical Biochemistry, ISSN 0003-2697, 05/2018, Volume 549, pp. 143 - 148
IgG molecules exert important effector functions including complement-dependent cytotoxicity (CDC). Different IgG isotypes induce CDC effect with variation,... 
Monoclonal antibodies | C1q binding | FC binding | Antigen binding | THERAPEUTICS | CHEMISTRY, ANALYTICAL | EFFECTOR FUNCTIONS | CHIMERIC HUMAN | C1Q | ACTIVATION | FC-RECEPTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL RESEARCH METHODS | CLQ | HUMAN IGG1 | BINDING-SITE | COMPLEMENT COMPONENT
Journal Article
MOLECULAR IMMUNOLOGY, ISSN 0161-5890, 06/2004, Volume 41, Issue 2-3, pp. 173 - 183
Journal Article
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, ISSN 0145-305X, 05/2014, Volume 44, Issue 1, pp. 70 - 75
The Clq-domain-containing (ClqDC) proteins, which are involved in various processes of vertebrates, are important pattern recognition receptors in innate... 
Biomarker | IMMUNE GENE REPERTOIRE | COMPLEMENT | FISHERIES | ZOOLOGY | PATTERN | Mytilus coruscus | Innate immunity | C1Q-DOMAIN-CONTAINING PROTEINS | IMMUNOLOGY | Clq-domain-containing protein (ClqDC) | Pattern recognition receptor
Journal Article
Journal Article
Journal of Neuroinflammation, ISSN 1742-2094, 03/2017, Volume 14, Issue 1, p. 48
Background: The complement cascade not only provides protection from infection but can also mediate destructive inflammation. Complement is also involved in... 
C1q | Expression | Conditional knockout | Complement | Mouse model | Alzheimer's | Microglia | PROTEIN | COMPLEMENT ACTIVATION | ALZHEIMERS-DISEASE | NEURODEGENERATION | IMMUNOLOGY | NEUROSCIENCES | CRE-RECOMBINASE ACTIVITY | CLQ EXPRESSION | INTERFERON-GAMMA | MODELS | A-BETA | MICE | Animals, Newborn | Microglia - metabolism | Brain - cytology | Mice, Inbred C57BL | Receptors, Chemokine - metabolism | Gene Expression Regulation - physiology | Mice, Transgenic | Complement C1q - genetics | RNA, Messenger - metabolism | Thy-1 Antigens - metabolism | CD11b Antigen - genetics | Neuropil - metabolism | Animals | Thy-1 Antigens - genetics | beta-Galactosidase - metabolism | Luminescent Proteins - genetics | Mice | Neurons - metabolism | CD11b Antigen - metabolism | Complement C1q - deficiency | beta-Galactosidase - genetics | Receptors, Chemokine - genetics | CX3C Chemokine Receptor 1 | Luminescent Proteins - metabolism | Animal models | Disease | Synaptogenesis | Central nervous system | Homeostasis | Nervous system | Neuronal-glial interactions | Proteins | Angiogenesis | Developmental stages | Neurodegeneration | Rodents | Dementia disorders | Bone marrow | Amyloid | Alzheimer's disease | Neurodegenerative diseases | Neurons | Astrocytes | Inflammation | Gene expression | Neural networks | Rheumatoid arthritis | Alleles | Laboratory animals | Animal cognition | Tumors | Apoptosis
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 01/2018, Volume 536, Issue 1, pp. 434 - 439
Polydiacetylene (pDA) micelles have been demonstrated to be effective drug carriers for cancer therapy in mouse model. However, little is known about their... 
Surface charge | C1q | Complement | Innate immune system | Polydiacetylene micelle | ACTIVATION | RECOGNITION | STABILIZATION | CLQ | FACTOR-H | DELIVERY | PHARMACOLOGY & PHARMACY | BINDING | LIPOSOMES | Drugs | Drug delivery systems | Surface active agents | Analysis | Lectins | Protein binding | Vehicles | Life Sciences | Biomolecules | Biochemistry, Molecular Biology
Journal Article
Journal of Immunotoxicology, ISSN 1547-691X, 01/2019, Volume 16, Issue 1, pp. 82 - 86
Measurements of complement-bound circulating immune complexes (cCICs) in pre-clinical studies may provide important information about the etiology of certain... 
Immunoassay | immune complex | immunogenicity | complement 3 (C3) | QUANTITY | AFFINITY | DISEASE | RATS | ANTIBODY | CLQ | SERUM | TOXICOLOGY | complement 3 (c3) | immunoassay
Journal Article
Journal Article