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1. Full Text Modulation of cell responses to Ag‐(MeO2MA‐co‐OEGMA): Effects of nanoparticle surface hydrophobicity and serum proteins on cellular uptake and toxicity
by Anderson, Christopher R and Gnopo, Yehou D. M and Gambinossi, Filippo and Mylon, Steven E and Ferri, James K
Journal of Biomedical Materials Research Part A, ISSN 1549-3296, 04/2018, Volume 106, Issue 4, pp. 1061 - 1071
Nanoparticle (NP) interactions with cellular systems are influenced by both NP physico‐chemical properties and the presence of surface‐bound proteins that are... 
protein adsorption | silver nanoparticles | receptor‐mediated endocytosis | surface functionalization | cytotoxicity | cell uptake | Silver | Ethylene glycol | Adsorption | Analysis | Methyl ether | Chemical properties | Methyl methacrylate | Protein binding | Blood proteins | Clathrin | Reactive oxygen species | Caveolae | Toxicity | Ethylene | Cytotoxicity | Hydrophobicity | Serum proteins | Cobalt | 1-Phosphatidylinositol 3-kinase | Nanoparticles | Proteins | Endocytosis | Polyethylene glycol | Fibroblasts | Biocompatibility | Inhibition | Polymethyl methacrylate
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2. Full Text Enhanced AOX accumulation and aquatic toxicity during 2,4,6-trichlorophenol degradation in a Co(II)/peroxymonosulfate/Cl− system
by Fang, Changling and Xiao, Dongxue and Liu, Wenqian and Liu, Jianshe and Lou, Xiaoyi and Zhou, Jun and Wang, Zhaohui
Chemosphere, ISSN 0045-6535, 02/2016, Volume 144, pp. 2415 - 2420
Chloride ion is known to affect on degradation kinetics in different ways during HO and -based advanced oxidation processes (AOPs). However, its effect on... 
Active chlorine species | Sulfate radical | Polychlorinated organic compounds | Hydroxyl radical | FENTON | IONS | ADVANCED OXIDATION | AZO-DYE | ENVIRONMENTAL SCIENCES | SULFATE | KINETICS | PEROXYMONOSULFATE | RADICALS | WATER | Chlorophenols - chemistry | Photobacterium - drug effects | Oxidation-Reduction | Waste Water - chemistry | Peroxides - chemistry | Water Pollutants, Chemical - chemistry | Waste Disposal, Fluid | Chlorides - chemistry | Chlorophenols - toxicity | Hydrogen Peroxide - chemistry | Ultraviolet Rays | Water Pollutants, Chemical - toxicity | Cobalt - chemistry | Index Medicus | Degradation | Hydrogen peroxide | Chlorination | Toxicity | Chlorides | Byproducts | Evolution | Salinity
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3. Cobalt in hard metals and cobalt sulfate, gallium arsenide, indium phosphide and vanadium pentoxide
by Altamirano-Lozano, Mario and Beyersmann, Detmar and Carter, Dean E and Fowler, Bruce A and Fubini, Bice and Kielhorn, Janet and Kirsch-Volders, Micheline and Kucera, Jan and Kusaka, Yukinori and Lasfargues, Gerard and Lison, Dominique and Mangelsdor, Inge and McElvenny, Damien and Nemery, Benoit and Roycroft, Joseph and Svartengren, Magnus and Junghans, Ted and Olin, Steve and Renne, Roger and Longfellow, David G and Ziegler-Skylakakis, Kyriakoula and Baan, Robert and Cogliano, Vincent and El Ghissassi, Fatiha and Fletcher, Tony and Friesen, Marlin and Grosse, Yann and Napalkov, Nikolai and Secretan, Béatrice and Straif, Kurt and Wang, Zhao-Qi and Williams, Rosamund and World Health Organization and International Agency for Research on Cancer and IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
IARC monographs on the evaluation of carcinogenic risks to humans / World Health Organization, International Agency for Research on Cancer, ISSN 1017-1606, 2006, Volume 86, pp. 1 - 294
Carcinogens | Gallium | Arsenic | Tungsten | Vanadium | Indium | Cobalt | Physiological effect | Health aspects | Rabbits | Guinea Pigs | Arsenicals | Humans | Rats | Gallium - toxicity | Metals - toxicity | Carcinogens - toxicity | Cobalt - toxicity | Animals | Phosphines - toxicity | Vanadium Compounds - toxicity | Mice | Indium - toxicity | Index Medicus
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4. Full Text Intracellular uptake and toxicity of Ag and CuO nanoparticles: A comparison between nanoparticles and their corresponding metal ions
by Cronholm, Pontus and Karlsson, Hanna L and Hedberg, Jonas and Lowe, Troy A and Winnberg, Lina and Elihn, Karine and Wallinder, Inger Odnevall and Möller, Lennart and Yt- och korrosionsvetenskap and Kemi and KTH and Skolan för kemivetenskap (CHE)
Small, ISSN 1613-6810, 04/2013, Volume 9, Issue 7, pp. 970 - 982
An increased understanding of nanoparticle toxicity and its impact on human health is essential to enable a safe use of nanoparticles in our society. The aim... 
nanoparticle dissolution | copper nanoparticles | silver nanoparticles | cellular uptake | nanotoxicology | PHYSICS, CONDENSED MATTER | OXIDATIVE STRESS | PHYSICS, APPLIED | ALVEOLAR EPITHELIAL-CELLS | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | COPPER | ENHANCED RAMAN-SCATTERING | CHEMISTRY, MULTIDISCIPLINARY | IN-VITRO | GENOTOXICITY | OXIDE NANOPARTICLES | SPECTROSCOPY | COBALT NANOPARTICLES | Cell Line | Microscopy, Electron, Transmission | Humans | Metal Nanoparticles - chemistry | Silver - chemistry | Microscopy, Confocal | Metal Nanoparticles - toxicity | Copper - chemistry | Biological Transport | Silver Nitrate - chemistry | Spectrum Analysis, Raman | DNA Damage | Metal Nanoparticles - ultrastructure | Nanoparticles | Analysis | Copper oxide | Electron microscopy | Spyware | Cuprite | Corrosion and anti-corrosives | Microscopy | Toxicity | DNA damage | Cells | Apoptosis | Index Medicus | Naturvetenskap | Kemi | Natural Sciences | Annan kemi | Chemical Sciences | Other Chemistry Topics
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5. Full Text Cobalt(III) Chaperone Complexes of Curcumin: Photoreduction, Cellular Accumulation and Light‐Selective Toxicity towards Tumour Cells
by Renfrew, Anna K and Bryce, Nicole S and Hambley, Trevor
Chemistry – A European Journal, ISSN 0947-6539, 10/2015, Volume 21, Issue 43, pp. 15224 - 15234
Light‐activated prodrugs offer the potential for highly selective tumour targeting. However, the application of many photoactivated chemotherapeutics is... 
prodrug | turn‐on fluorescence | cobalt | photochemotherapy | curcumin | turn-on fluorescence | 2-PHOTON EXCITATION | ACTIVATION | PHOTODYNAMIC THERAPY | PHOTOINDUCED ELECTRON-TRANSFER | DIPYRIDOPHENAZINE COMPLEXES | CHEMISTRY, MULTIDISCIPLINARY | CANCER-THERAPY | COPPER(II) COMPLEXES | VISIBLE-LIGHT | NITRIC-OXIDE | RUTHENIUM COMPLEXES | Cell Hypoxia | Cobalt - pharmacology | Curcumin - chemistry | Humans | Light | Curcumin - pharmacology | Cell Line, Tumor | Ligands | Prodrugs - chemistry | Prodrugs - pharmacology | Cobalt - chemistry | Fluorescence | Photolysis | Cobalt | Fluorescence microscopy | Tumors | Toxicity | Cytotoxicity | Index Medicus | Drugs | Cellular | Wavelengths | Tumours | Activation | Chemical compounds
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6. Full Text Exposure of engineered nanoparticles to human lung epithelial cells: Influence of chemical composition and catalytic activity on oxidative stress
by Limbach, Ludwig K and Wick, Peter and Manser, Pius and Grass, Robert N and Bruinink, Arie and Stark, Wendelin J
Environmental Science and Technology, ISSN 0013-936X, 06/2007, Volume 41, Issue 11, pp. 4158 - 4163
The chemical and catalytic activity of nanoparticles has strongly contributed to the current tremendous interest in engineered nanomaterials and often serves... 
OXIDE-SILICA AEROGELS | MIXED OXIDES | ENVIRONMENTAL SCIENCES | EPOXIDATION CATALYSTS | ENGINEERING, ENVIRONMENTAL | ULTRAFINE PARTICLES | NANOMATERIALS | SOL-GEL | TOXICITY | STRUCTURAL-PROPERTIES | CYTOTOXICITY | FLAME SYNTHESIS | Reactive Oxygen Species - metabolism | Oxidative Stress | Manganese - toxicity | Epithelial Cells - drug effects | Humans | Iron - chemistry | Metal Nanoparticles - chemistry | Silicon Dioxide - chemistry | Cells, Cultured | Titanium - chemistry | Manganese - chemistry | Lung - cytology | Titanium - toxicity | Cobalt - toxicity | Metal Nanoparticles - toxicity | Silicon Dioxide - toxicity | Lung - drug effects | Lung - metabolism | Iron - toxicity | Toxicity Tests | Cobalt - chemistry | Nanotechnology | Metal Nanoparticles - ultrastructure | Nanoparticles | Catalytic oxidation | Lungs | Chemical synthesis | Chemical compounds | Cells | Q1 | Oxygen | heavy metals | Lung | Metals | silica | Particulates | Cobalt | Sedimentation | Risk assessment | nanotechnology | Chemical composition | Oxidation | oxidative stress | Manganese | Index Medicus
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7. Full Text Fructose‐1,6‐bisphosphate aldolase (class II) is the primary site of nickel toxicity in Escherichia coli
by Macomber, Lee and Elsey, Scott P and Hausinger, Robert P
Molecular Microbiology, ISSN 0950-382X, 12/2011, Volume 82, Issue 5, pp. 1291 - 1300
Nickel is toxic to all forms of life, but the mechanisms of cell damage are unknown. Indeed, environmentally relevant nickel levels (8 µM) inhibit wild‐type... 
TRANSPORT-SYSTEM | HOMEOSTASIS | GENE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALCALIGENES-EUTROPHUS | PURIFICATION | FRUCTOSE-1,6-DIPHOSPHATE ALDOLASE | MICROBIOLOGY | SUPEROXIDE DISMUTASES | CROOKES STRAIN | IDENTIFICATION | COBALT | Fructose-Bisphosphate Aldolase - antagonists & inhibitors | Escherichia coli - enzymology | Enzyme Inhibitors - metabolism | Escherichia coli - drug effects | Carbohydrate Metabolism | Mutant Proteins - metabolism | Nickel - toxicity | Fructose-Bisphosphate Aldolase - isolation & purification | Enzyme Inhibitors - toxicity | Escherichia coli - metabolism | Fructose-Bisphosphate Aldolase - metabolism | Kinetics | Culture Media - chemistry | Nickel - metabolism | Mutant Proteins - antagonists & inhibitors | Glycerin | Lactates | Molecular genetics | Escherichia coli | Glycerol | Nickel | Glucose | Fructose | Dextrose | Mutation | E coli | Microbiology | Toxicity | Index Medicus | metalloprotein | metal substitution | allosteric regulation | glutathione | glycolysis
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8. Full Text Molecular analysis of chromium and cobalt-related toxicity
by Scharf, Brian and Clement, Cristina C and Zolla, Valerio and Perino, Giorgio and Yan, Bo and Elci, S. Gokhan and Purdue, E and Goldring, S and MacAluso, Frank and Cobelli, Neil and Vachet, Richard W and Santambrogio, Laura
Scientific Reports, ISSN 2045-2322, 07/2014, Volume 4, Issue 1, pp. 5729 - 5729
Occupational and environmental exposure to Co and Cr has been previously linked to a wide array of inflammatory and degenerative conditions and cancer.... 
NICKEL | MULTIDISCIPLINARY SCIENCES | FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE | BLOOD COBALT | WEAR | ARTHROPLASTY | TOTAL HIP-REPLACEMENT | CORROSION | METAL-ION LEVELS | FAILURE | CELL-DEATH | Protein Carbonylation | Fructose-Bisphosphate Aldolase - antagonists & inhibitors | Oxidative Stress | Catalase - antagonists & inhibitors | Humans | Middle Aged | Male | Chromium - chemistry | Fructose-Bisphosphate Aldolase - chemistry | Aged, 80 and over | Adult | Chromium - toxicity | Female | Metal Nanoparticles - chemistry | Mice, Inbred C57BL | Cells, Cultured | Hip Prosthesis | Arthroplasty, Replacement, Hip | Hip Joint - immunology | Hip Joint - drug effects | Metal-on-Metal Joint Prostheses | Cobalt - toxicity | Metal Nanoparticles - toxicity | Animals | Aged | Cobalt - chemistry | Phagocytosis | Catalase - chemistry | Toxicity | Alloys | Ions | Inflammation | Occupational exposure | Macrophages | Cobalt | Corrosion | Catalase | Affinity chromatography | Particulate matter | Chromium | Cancer | Index Medicus
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9. Full Text Effect of Heavy Metals on Inhibition of Root Elongation in 23 Cultivars of Flax (Linum usitatissimum L.)
by Soudek, Petr and Katrušáková, Adéla and Sedláček, Lukáš and Petrová, Šárka and Kočí, Vladimír and Maršík, Petr and Griga, Miroslav and Vaněk, Tomáš
Archives of Environmental Contamination and Toxicology, ISSN 0090-4341, 8/2010, Volume 59, Issue 2, pp. 194 - 203
The effect of toxic metals on seed germination was studied in 23 cultivars of flax (Linum usitatissimum L.). Toxicity of cadmium, cobalt, copper, zinc, nickel,... 
Pollution, general | Environmental Health | Ecotoxicology | Environment | Environmental Monitoring/Analysis | Environmental Chemistry | Soil Science & Conservation | ENVIRONMENTAL SCIENCES | SEED-GERMINATION | CADMIUM | SEEDLINGS | SINAPIS-ALBA | TRACE-METALS | COPPER | TOXICITY | TOXICOLOGY | ACCUMULATION | PLANT-GROWTH | LEAD | Biodegradation, Environmental | Germination - drug effects | Flax - growth & development | Cadmium - toxicity | Nickel - toxicity | Arsenic - toxicity | Flax - drug effects | Growth Inhibitors - toxicity | Plant Roots - drug effects | Soil Pollutants - toxicity | Dose-Response Relationship, Drug | Cobalt - toxicity | Metals, Heavy - toxicity | Chromium - toxicity | Zinc - toxicity | Copper - toxicity | Flax - classification | Lead - toxicity | Plant Roots - growth & development | Toxicity Tests | Studies | Principal components analysis | Flowers & plants | Environmental monitoring | Toxicity | Heavy metals | Toxicology | Roots | Chromium | Inhibition | Flax | Elongation | Zinc | Index Medicus
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10. Full Text Predicting acute and chronic effects of wood preservative products in daphnia magna and pseudokirchneriella subcapitata based on the concept of concentration addition
by Coors, Anja and Weisbrod, Barbara and Schoknecht, Ute and Sacher, Frank and Kehrer, Anja
Environmental Toxicology and Chemistry, ISSN 0730-7268, 02/2014, Volume 33, Issue 2, pp. 382 - 393
The current European legislation requires that combined effects of the active substances and any substance of concern contained in biocidal products are taken... 
Adjuvant | Coformulant | Mixture toxicity | Biocide | ENVIRONMENTAL SCIENCES | CHEMICALS | SYSTEMS | TOXICITY | TOXICOLOGY | PESTICIDE MIXTURES | Daphnia - physiology | Risk Assessment | Wood | Dimethylamines - toxicity | Fungicides, Industrial - toxicity | Chlorophyta - growth & development | Disinfectants - toxicity | Reproduction - drug effects | Cobalt - toxicity | Daphnia - drug effects | Animals | Triazoles - toxicity | Water Pollutants, Chemical - toxicity | Chlorophyta - drug effects | Insecticides - toxicity | Carbamates - toxicity | Phenylcarbamates - toxicity | Aquatic life | Effects | Toxicity | Algae | Risk assessment | Predictions | Index Medicus | Formulations | Preservatives | Protective | Biocides | Ecological risk assessment
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11. Full Text Photocatalytic degradation of amitriptyline, trazodone and venlafaxine using modified cobalt-titanate nanowires under UV–Vis radiation: Transformation products and in silico toxicity
by Osawa, Rodrigo A and Barrocas, Beatriz T and Monteiro, Olinda C and Conceição Oliveira, M and Florêncio, M. Helena
Chemical Engineering Journal, ISSN 1385-8947, 10/2019, Volume 373, pp. 1338 - 1347
This work investigated the catalytic ability of modified cobalt-titanate nanowires (Co-TNW) on photodegradation of three antidepressants: amitriptyline (AMI),... 
Transformation products | Modified cobalt-titanate nanowire | UV−Vis photocatalysis | In silico toxicity prediction | Antidepressants | UHPLC-QTOF-MS/MS | ELUCIDATION | WASTE-WATER TREATMENT | RESOLUTION MASS-SPECTROMETRY | IDENTIFICATION | PERFORMANCE LIQUID-CHROMATOGRAPHY | ENGINEERING, CHEMICAL | PHARMACEUTICAL RESIDUES | REMOVAL | UV-Vis photocatalysis | ENGINEERING, ENVIRONMENTAL | DRUGS | PHOTODEGRADATION | SOLID-PHASE EXTRACTION | Photolysis | Radiation | Trazodone | Catalysis | Cobalt | Mass spectrometry | High performance liquid chromatography
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12. Full Text Ru II (p-cymene) Compounds as Effective and Selective Anticancer Candidates with No Toxicity in Vivo
by Lenis-Rojas, Oscar A and Robalo, M. Paula and Tomaz, Ana Isabel and Carvalho, Andreia and Fernandes, Alexandra R and Marques, Fernanda and Folgueira, Mónica and Yánez, Julián and Vázquez-García, Digna and López Torres, Margarita and Fernández, Alberto and Fernández, Jesús J
Inorganic Chemistry, ISSN 0020-1669, 11/2018, Volume 57, Issue 21, pp. 13150 - 13166
Ruthenium(II) complexes are currently considered a viable alternative to the widely used platinum complexes as efficient anticancer agents. We herein present... 
POLYPYRIDYL COMPLEXES | DRUG | RUTHENIUM(II) ARENE COMPLEXES | ANTIPROLIFERATIVE ACTIVITY | DNA-BINDING | COBALT COMPLEXES | PIANO-STOOL COMPLEXES | CYTOTOXIC ACTIVITY | METAL-COMPLEXES | CELL-DEATH | CHEMISTRY, INORGANIC & NUCLEAR | Apoptosis - drug effects | Antineoplastic Agents - chemical synthesis | Humans | Structure-Activity Relationship | Ruthenium - chemistry | Dose-Response Relationship, Drug | Monoterpenes - pharmacology | Monoterpenes - adverse effects | Ruthenium - adverse effects | Antineoplastic Agents - adverse effects | Coordination Complexes - pharmacology | Antineoplastic Agents - pharmacology | Molecular Structure | Zebrafish | Antineoplastic Agents - chemistry | Coordination Complexes - chemistry | Ruthenium - pharmacology | Animals | Coordination Complexes - adverse effects | Cell Line, Tumor | Coordination Complexes - chemical synthesis | Monoterpenes - chemistry | Cell Proliferation - drug effects | Cell Cycle - drug effects | Drug Screening Assays, Antitumor
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13. Full Text Cobalt toxicity — an emerging clinical problem in patients with metal‐on‐metal hip prostheses?
by Mao, Xinzhan and Wong, Andrew A and Crawford, Ross W
Medical Journal of Australia, ISSN 0025-729X, 06/2011, Volume 194, Issue 12, pp. 649 - 651
We report two Australian patients with possible cobalt toxicity related to metal-on-metal total hip replacements. Both patients were treated for osteoarthritis... 
Musculoskeletal diseases | Nervous system diseases | Poisoning | Anatomy and physiology | MEDICINE, GENERAL & INTERNAL | IONS | INDUCE CHEMOKINE SECRETION | ARTHROPLASTY | Cobalt - toxicity | Humans | Middle Aged | Prosthesis Failure - adverse effects | Hip Prosthesis - adverse effects | Female | Male | Aged | Poisons | Patients | Surgery | Metals | Index Medicus
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14. Full Text Toxicity of porcelain-fused-to-metal substrate to zebrafish (Danio rerio) embryos and larvae
by Zhao, Libo and Si, Jing and Wei, Yuan and Li, Sirui and Jiang, Yanjiao and Zhou, Rong and Liu, Bin and Zhang, Hong
Life Sciences, ISSN 0024-3205, 06/2018, Volume 203, pp. 66 - 71
Porcelain-fused-to-metal (PFM) crowns are a standard restoration technique in dentistry, but toxicity of PFM in vivo has not been systematically evaluated. The... 
Zebrafish embryos | PFM | Biotoxicity | MEDICINE, RESEARCH & EXPERIMENTAL | BIOCOMPATIBILITY | DENTAL ALLOYS | IONS | EVOLUTION | HATCHING ENZYME GENES | PURIFICATION | FISH | PHARMACOLOGY & PHARMACY | CYTOTOXICITY | EXPRESSION | EXPOSURE | Yuan (China) | Embryonic development | Boron steel | Heart beat | Mortality | Steel alloys | Palladium | Chromium alloys | Chrome-nickel steel | Larvae | Surgical implants | Hatchability | Toxicity | Metals | Cobalt | Titanium base alloys | Dental restorative materials | Porcelain | Dental materials | Restoration | Leachates | Biocompatibility | Dental alloys | Swimming | Gold | Gold base alloys | Therapeutic applications | Alloys | Zebrafish | Dentistry | Embryos | Tensile strength | Substrates | Heart rate | Silver | Nickel chromium alloys | Swimming behavior | Chromium | In vivo methods and tests | Nickel | Saliva | Index Medicus
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