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index medicus (314) 314
animals (280) 280
biochemistry & molecular biology (123) 123
cobra neurotoxin proteins - metabolism (113) 113
amino acid sequence (110) 110
molecular sequence data (95) 95
venom (89) 89
receptors, nicotinic - metabolism (81) 81
humans (79) 79
mice (69) 69
cobra neurotoxin proteins - chemistry (65) 65
binding sites (59) 59
protein conformation (57) 57
receptors, cholinergic - metabolism (56) 56
elapid venoms - metabolism (52) 52
pharmacology & pharmacy (51) 51
models, molecular (50) 50
protein binding (49) 49
proteins (48) 48
elapid venoms - chemistry (44) 44
toxicology (44) 44
torpedo (43) 43
rats (41) 41
elapidae (39) 39
cobra neurotoxin proteins - pharmacology (38) 38
kinetics (35) 35
male (35) 35
toxins (35) 35
bungarotoxins - metabolism (34) 34
snakes (33) 33
biophysics (32) 32
neurotoxin (31) 31
analysis (29) 29
cobra venom (29) 29
neurotoxins (29) 29
binding, competitive (26) 26
amino-acid-sequence (25) 25
cobrotoxin (25) 25
neurotoxins - metabolism (25) 25
snake venom (25) 25
binding (24) 24
protein structure, secondary (24) 24
crystal-structure (23) 23
receptors, nicotinic - chemistry (23) 23
acetylcholine-receptor (22) 22
elapid venoms - toxicity (22) 22
ligands (22) 22
snake-venom (22) 22
structure-activity relationship (22) 22
base sequence (21) 21
alpha-bungarotoxin (20) 20
chromatography, high pressure liquid (20) 20
cobra neurotoxin proteins - toxicity (20) 20
in vitro techniques (20) 20
neurotoxins - chemistry (20) 20
circular dichroism (19) 19
elapidae - metabolism (19) 19
molecular weight (19) 19
sequence alignment (19) 19
sequence homology, amino acid (19) 19
acetylcholine (18) 18
alpha7 nicotinic acetylcholine receptor (18) 18
cell biology (18) 18
cobra cardiotoxin proteins - chemistry (18) 18
cobra neurotoxin proteins - genetics (18) 18
complex mixtures (18) 18
elapid venoms - pharmacology (18) 18
female (18) 18
protein structure, tertiary (18) 18
purification (18) 18
poisonous snakes (17) 17
electrophoresis, polyacrylamide gel (16) 16
phospholipase a (16) 16
protein (16) 16
receptors (16) 16
research article (16) 16
spectrometry, fluorescence (16) 16
toxin (16) 16
fluorescence (15) 15
magnetic resonance spectroscopy (15) 15
mass spectrometry (15) 15
research (15) 15
acetylcholine - metabolism (14) 14
bungarotoxin (14) 14
cardiotoxin (14) 14
cloning (14) 14
medicine (14) 14
nicotinic acetylcholine receptor (14) 14
protein folding (14) 14
site-directed mutagenesis (14) 14
snake (14) 14
alpha-neurotoxins (13) 13
apoptosis (13) 13
cell membrane - metabolism (13) 13
cloning, molecular (13) 13
cobra (13) 13
cobra cardiotoxin proteins - pharmacology (13) 13
cobra cardiotoxin proteins - toxicity (13) 13
cobra neurotoxin proteins - immunology (13) 13
cytotoxicity (13) 13
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The EMBO Journal, ISSN 0261-4189, 04/2005, Volume 24, Issue 8, pp. 1512 - 1522
Journal Article
Biochemical Journal, ISSN 0264-6021, 09/2013, Volume 454, Issue 2, pp. 303 - 310
To identify high-affinity interactions between long-chain α-neurotoxins and nicotinic receptors, we determined the crystal structure of the complex between... 
Molecular recognition | Neurotoxin | Nicotinic acetylcholine receptor | Crystal structure | Reptilian Proteins - chemistry | Nicotinic Agonists - metabolism | Cobra Neurotoxin Proteins - metabolism | Pyridines - chemistry | Humans | Recombinant Fusion Proteins - metabolism | Nicotinic Agonists - chemistry | Receptors, Nicotinic - chemistry | Carrier Proteins - chemistry | Protein Interaction Domains and Motifs | Binding Sites | Peptide Fragments - genetics | Bridged Bicyclo Compounds, Heterocyclic - metabolism | Bungarotoxins - metabolism | Neurotoxins - chemistry | Peptide Fragments - metabolism | Receptors, Nicotinic - metabolism | Bridged Bicyclo Compounds, Heterocyclic - chemistry | Bungarotoxins - chemistry | Lymnaea | Models, Molecular | Mutant Proteins - metabolism | Recombinant Fusion Proteins - chemistry | Cobra Neurotoxin Proteins - chemistry | Bungarus | Carrier Proteins - genetics | Peptide Fragments - chemistry | Animals | Carrier Proteins - metabolism | Pyridines - metabolism | Mutant Proteins - chemistry | Ligands | Neurotoxins - metabolism | Protein Conformation | Receptors, Nicotinic - genetics | Amino Acid Substitution | Reptilian Proteins - metabolism | alpha7 Nicotinic Acetylcholine Receptor | Index Medicus | BASIC BIOLOGICAL SCIENCES | crystal structure | neurotoxin | molecular recognition | nicotinic acetylcholine receptor
Journal Article
Journal Article
Comparative Biochemistry and Physiology, Part C, ISSN 1532-0456, 07/2016, Volume 185-186, pp. 77 - 86
Journal Article
Journal of proteomics, 03/2017, Volume 157, p. 18
The venom proteome of Naja sputatrix (Javan spitting cobra) was elucidated through reverse-phase HPLC, nano-ESI-LCMS/MS and data mining. A total of 97 distinct... 
Antivenins - pharmacology | Animals | Cobra Neurotoxin Proteins - metabolism | Cobra Neurotoxin Proteins - antagonists & inhibitors | Antivenins - chemistry | Cobra Neurotoxin Proteins - toxicity | Mice | Cobra Neurotoxin Proteins - chemistry | Naja - metabolism | Mice, Inbred ICR
Journal Article
Biochemistry, ISSN 0006-2960, 06/2005, Volume 44, Issue 23, pp. 8326 - 8336
Cobrotoxin is known to bind with cysteine residues of biological Molecules Such as nicotine acetylcholine receptor. Cobrotoxin may modify IKKs and p50 through... 
DNA-BINDING | NEUROTOXINS | INFLAMMATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | COVALENT MODIFICATION | BINDING DOMAIN | KINASE IKK | GENERATION | CHANNELS | ACETYLCHOLINE-RECEPTOR | SUBUNIT | Cobra Neurotoxin Proteins - metabolism | Gene Silencing - drug effects | Luciferases - metabolism | NF-kappa B - metabolism | Astrocytes - enzymology | DNA-Binding Proteins - metabolism | Protein Precursors - antagonists & inhibitors | Protein Precursors - physiology | Enzyme Inhibitors - chemistry | Protein Binding - drug effects | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Cysteine - metabolism | Protein-Serine-Threonine Kinases - metabolism | Astrocytes - drug effects | Cell Line | DNA-Binding Proteins - physiology | NF-kappa B - antagonists & inhibitors | DNA-Binding Proteins - antagonists & inhibitors | Enzyme Inhibitors - metabolism | NF-kappa B p50 Subunit | Cells, Cultured | Gene Expression Regulation - physiology | Rats | Signal Transduction - genetics | Cysteine - chemistry | Cobra Neurotoxin Proteins - chemistry | DNA-Binding Proteins - genetics | I-kappa B Kinase | Rats, Sprague-Dawley | Protein Precursors - metabolism | Binding, Competitive - drug effects | Gene Expression Regulation - drug effects | Animals | Signal Transduction - drug effects | NF-kappa B - physiology | Luciferases - antagonists & inhibitors | Signal Transduction - physiology | Mice | Astrocytes - metabolism | Index Medicus
Journal Article
FEBS Letters, ISSN 0014-5793, 04/2004, Volume 564, Issue 3, pp. 319 - 324
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 08/2007, Volume 359, Issue 3, pp. 413 - 418
We investigate the interactions between the long chain α-cobratoxin (Cbtx) and the nicotinic acetylcholine receptor using a rigid body docking procedure. The... 
Rigid body protein–protein docking | Nicotinic acetylcholine receptor | Model | Acetylcholine-binding protein | α-Cobratoxin | Structure | Complex | Rigid body protein-protein docking | DOMAIN | PROTEIN | RECOGNITION | CRYSTAL-STRUCTURE | TOXIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | rigid body protein-protein docking | alpha-cobratoxin | POTENTIALS | structure