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Progress in Neuropsychopharmacology & Biological Psychiatry, ISSN 0278-5846, 03/2020, Volume 98, p. 109791
Substance use is strongly associated with impaired decision making, with cocaine use particularly linked to elevated risky and impulsive choice. It is not... 
Self-administration | Cocaine | Choice | Risk taking | PSYCHIATRY | ADMINISTERED COCAINE | NEUROSCIENCES | RAT MODEL | CLINICAL NEUROLOGY | INTRAVENOUS COCAINE | INDIVIDUAL-DIFFERENCES | STRAIN DIFFERENCES | DRUG-INTAKE | IMPULSIVE CHOICE | ANIMAL-MODELS | PHARMACOLOGY & PHARMACY | OPPONENT-PROCESS ACTIONS | SEX-DIFFERENCES
Journal Article
Brain Research, ISSN 0006-8993, 02/2020, Volume 1729, p. 146626
Pituitary adenylate cyclase-activating polypeptide (PACAP) was discovered thirty years ago, but its role in eating and drug use disorders has only recently... 
Alcohol | Receptors | Cocaine | Binge eating | Affective behavior | Nicotine
Journal Article
Behavioural Brain Research, ISSN 0166-4328, 02/2020, Volume 379, p. 112365
Re-exposure to drug or drug-associated cues after withdrawal can induce behavioral sensitization expression in animals or increase in the expected effect to... 
Nucleus accumbens | Cocaine | Locomotor sensitization | Orexin
Journal Article
Behavioural Brain Research, ISSN 0166-4328, 02/2020, Volume 379, p. 112275
Novelty seeking is a personality trait associated with an increased vulnerability for substance abuse. In rodents, elevated novelty seeking has been shown to... 
Sex differences | Cocaine | Novelty seeking | Psychostimulant | Stress | TetTag mouse model
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 01/2020, Volume 867, p. 172838
Dopamine, a neurotransmitter with 5 receptor subtypes, is critical to the dependence-forming properties of drugs of abuse. The role of the dopamine D receptor... 
Relapse | Ethanol | Ratio schedule | L-745,870 | PD 168,077 | D-4 RECEPTOR | ANTAGONIST | HIGH-AFFINITY | COCAINE | SEEKING BEHAVIOR | ANIMAL-MODELS | PHARMACOLOGY & PHARMACY | D4 RECEPTORS | AMPHETAMINE
Journal Article
Progress in Neuropsychopharmacology & Biological Psychiatry, ISSN 0278-5846, 01/2020, Volume 96, p. 109753
Social stress is associated with higher vulnerability to drug use, as it enhances the reinforcing effects of psychostimulants in rodents. Furthermore,... 
Chemokine | Cocaine | Inflammation | Social defeat | FRACTALKINE | SIGNALING PATHWAYS | DEFICIENCY LEADS | PSYCHIATRY | HIPPOCAMPAL | RECEPTOR | NEUROSCIENCES | CLINICAL NEUROLOGY | ADOLESCENT MICE | MICROGLIA | NEURONS | PHARMACOLOGY & PHARMACY | STRESS | UP-REGULATION
Journal Article
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, ISSN 0924-977X, 01/2020
Even though men are more likely to use drugs, women tend to progress faster from drug use to drug abuse, especially in the case of psychostimulants such as... 
Journal Article
The American Journal of Drug and Alcohol Abuse, ISSN 0095-2990, 01/2020, Volume 46, Issue 1, pp. 22 - 30
Background: Data from the Global Burden of Disease Study 2016 recently estimated that after opioid and cannabis use disorders, cocaine use disorders were among... 
brain expression | cocaine misuse | Addiction | RNA-seq | microarrays
Journal Article
Brain Behavior and Immunity, ISSN 0889-1591, 01/2020, Volume 83, pp. 288 - 292
C-C chemokine receptor type 5, also known as CCR5 or CD195, is best known as a viral co-receptor that facilitates entry of HIV into cells. Evidence that CCR5... 
Chemokine | Cocaine | Maraviroc | Addiction | CCR5 | RANTES
Journal Article
Addiction Biology, ISSN 1355-6215, 01/2020, Volume 25, Issue 1, pp. e12716 - n/a
The application of behavioral economic demand theory in addiction science has proved useful for evaluating individual characteristics underlying abuse... 
cocaine | self‐administration | opioid | rodent | sex | threshold | estrous | hormone | Preclinical Studies | Original
Journal Article
Addiction Biology, ISSN 1355-6215, 01/2020, Volume 25, Issue 1, pp. e12682 - n/a
The dopaminergic motive system is compromised in cocaine addiction. Abundant research has examined the roles of the dopaminergic midbrain and ventral striatum... 
fMRI | cocaine addiction | hypothalamus
Journal Article
Brain Research, ISSN 0006-8993, 01/2020, Volume 1726, p. 146502
The abuse of stimulants, such as methamphetamine (METH), is associated with treatment non-compliance, a greater risk of viral transmission, and the more rapid... 
COAT PROTEIN | ALCOHOL | IMMUNODEFICIENCY-VIRUS-INFECTION | ILLICIT DRUG-USE | COCAINE | EXPRESSION | NEUROSCIENCES | PREFRONTAL CORTEX | AFRICAN-AMERICAN | BRAIN | DARK SIDE
Journal Article
Neuropharmacology, ISSN 0028-3908, 01/2020, Volume 162, p. 107852
The United States is in the midst of an opioid epidemic and is thus experiencing unprecedented levels of opioid exposure. A growing body of evidence has... 
Opioid | Self-administration | Morphine | Cocaine | Transgenerational | Oxycodone
Journal Article
Psychopharmacology, ISSN 0033-3158, 01/2020, Volume 237, Issue 1, pp. 55 - 68
Comorbid use of heroin and cocaine is highly prevalent among drug users and can greatly increase addiction risk. Nonetheless, little is known regarding how a... 
Cues | Drugs | Drug abuse | Sensitivity analysis | Narcotics | Extinction | Elasticity | Drug self-administration | Sensitivity | Reactivity | Motivation | Addiction | Reinstatement | Cocaine | Heroin
Journal Article