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Environmental Health Perspectives, ISSN 0091-6765, 07/2013, Volume 121, Issue 7, pp. 818 - 824
BACKGROUND: Inorganic arsenic (iAs) causes cancer and possibly other adverse health outcomes. Arsenic-based drugs are permitted in poultry production; however,... 
Antimicrobial | FDA | Roxarsone | Arsenic | Poultry | Nitarsone | Chicken | Food and Drug Administration | MORTALITY | antimicrobial | RISKS | chicken | poultry | ACID | nitarsone | arsenic | ENVIRONMENTAL SCIENCES | BIOTRANSFORMATION | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | roxarsone | POULTRY LITTER | SPECIATION | TOXICOLOGY | DRINKING-WATER | EXPOSURE | RICE | United States - epidemiology | Cooking | Coccidiostats - metabolism | Lung Neoplasms - chemically induced | Humans | Environmental Pollutants - metabolism | Urinary Bladder Neoplasms - chemically induced | Chickens - metabolism | Pectoralis Muscles - metabolism | Arsenicals - metabolism | Roxarsone - administration & dosage | Environmental Pollutants - administration & dosage | Roxarsone - metabolism | Urinary Bladder Neoplasms - epidemiology | Coccidiostats - analysis | Risk Assessment | Meat - analysis | Coccidiostats - administration & dosage | Mass Spectrometry - veterinary | Arsenicals - analysis | Environmental Exposure | Arsenicals - administration & dosage | Animals | Lung Neoplasms - epidemiology | Roxarsone - analysis | Chromatography, High Pressure Liquid - veterinary | Environmental Pollutants - analysis | Chronic diseases | Research | Health aspects | Chickens | Risk factors | Drugs | Studies | Sales | Antibiotics | Laboratories | FDA approval | Public health | Marketing | Cancer | Shipments | Index Medicus | Heating | Consumers | Meat
Journal Article
Food Additives & Contaminants: Part A, ISSN 1944-0049, 09/2013, Volume 30, Issue 9, pp. 1546 - 1555
Roxarsone is an organoarsenic feed additive that can be metabolised to other higher toxic arsenic (As) species in animal manure such as arsenate, arsenite,... 
arsenic species | turnip | roxarsone | bioavailability | lettuce | animal manure | ACID | FOOD SCIENCE & TECHNOLOGY | RADISH | TOXICITY | FATE | PHOSPHATE | POULTRY LITTER | SPECIATION | PLANTS | ROOTS | TOXICOLOGY | ACCUMULATION | CHEMISTRY, APPLIED | Roxarsone - pharmacokinetics | Manure | Pesticide Residues - metabolism | Coccidiostats - metabolism | Biological Availability | Food Additives - pharmacokinetics | Plant Tubers - metabolism | Food Additives - analysis | Food Contamination - prevention & control | Vegetables - chemistry | Pesticide Residues - adverse effects | Arsenicals - metabolism | Brassica napus - metabolism | China | Roxarsone - metabolism | Pesticide Residues - analysis | Vegetables - metabolism | Brassica rapa - chemistry | Plant Components, Aerial - growth & development | Plant Roots - growth & development | Cacodylic Acid - metabolism | Brassica napus - growth & development | Lettuce - metabolism | Vegetables - growth & development | Brassica rapa - metabolism | Lettuce - chemistry | Plant Roots - metabolism | Coccidiostats - analysis | Plant Tubers - growth & development | Plant Components, Aerial - chemistry | Arsenicals - analysis | Lettuce - growth & development | Brassica napus - chemistry | Roxarsone - adverse effects | Food Additives - adverse effects | Brassica rapa - growth & development | Plant Components, Aerial - metabolism | Animals | Feces - chemistry | Chickens | Plant Roots - chemistry | Roxarsone - analysis | Cacodylic Acid - analysis | Food Additives - metabolism | Plant Tubers - chemistry | Coccidiostats - pharmacokinetics | Animal Feed | Index Medicus
Journal Article
British Journal of Nutrition, ISSN 0007-1145, 01/2013, Volume 109, Issue 1, pp. 76 - 88
The effects of a compound including the secondary metabolites of garlic, propyl thiosulphinate (PTS) and propyl thiosulphinate oxide (PTSO), on the in vitro... 
Eimeria acervulina | Garlic | Microarray techniques | Propyl thiosulphinate | Propyl thiosulphinate oxide | Chickens | LYMPHOID-TISSUES | HISTORICAL-PERSPECTIVE | NUTRITION & DIETETICS | EPITHELIAL-CELLS | CELL-ACTIVATING FACTOR | IMMUNE-RESPONSES | ALLIUM-SATIVUM | GENE-EXPRESSION | ANTIMICROBIAL ACTIVITY | INNATE IMMUNITY | EXTRACT | Sulfinic Acids - therapeutic use | Plant Extracts - chemistry | Coccidiostats - metabolism | Protozoan Proteins - antagonists & inhibitors | Immunity, Mucosal | Sulfinic Acids - chemistry | Coccidiosis - immunology | Garlic - chemistry | Coccidiostats - therapeutic use | Poultry Diseases - metabolism | Plant Extracts - metabolism | Avian Proteins - blood | Lymphocytes - immunology | Feces - parasitology | Coccidiosis - prevention & control | Sulfinic Acids - metabolism | Eimeria - growth & development | Weight Gain | Antibodies, Protozoan - analysis | Coccidiosis - parasitology | Lymphocytes - metabolism | Avian Proteins - metabolism | Profilins - antagonists & inhibitors | Parasite Egg Count | Eimeria - isolation & purification | Random Allocation | Coccidiostats - chemistry | Garlic - metabolism | Gene Expression Profiling - veterinary | Poultry Diseases - parasitology | Animals | Coccidiosis - veterinary | Poultry Diseases - prevention & control | Eimeria - immunology | Poultry Diseases - immunology | Plant Extracts - therapeutic use | Animal Feed | Avian Proteins - genetics | Animal diseases | Metabolites | Poultry | Medical immunity | Dietary supplements
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2014, Volume 9, Issue 5, p. e95970
Salinomycin raised hope to be effective in anti-cancer therapies due to its capability to overcome apoptosis-resistance in several types of cancer cells.... 
CANCER-CELLS | SURVIVAL | APOPTOSIS | MAINTENANCE | HEPATOCYTES | ACTIVATION | THYMIDINE ANALOGS | MULTIDISCIPLINARY SCIENCES | MITOCHONDRIA | GROWTH | INDUCTION | Reactive Oxygen Species - metabolism | Microtubule-Associated Proteins - genetics | Apoptosis - drug effects | Microtubule-Associated Proteins - metabolism | Humans | Green Fluorescent Proteins - genetics | Hepatocytes - metabolism | Autophagy - drug effects | Dose-Response Relationship, Drug | Hepatocytes - cytology | Flow Cytometry | RNA Interference | Carcinoma, Hepatocellular - genetics | Liver Neoplasms - pathology | Antineoplastic Agents - pharmacology | Autophagy - genetics | Pyrans - pharmacology | Hepatocytes - drug effects | Cell Survival - drug effects | Green Fluorescent Proteins - metabolism | Ubiquitin-Activating Enzymes - genetics | Liver Neoplasms - genetics | Cells, Cultured | Blotting, Western | Hep G2 Cells | Autophagy-Related Protein 7 | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Cell Line, Tumor | Cell Proliferation - drug effects | Coccidiostats - pharmacology | Carcinoma, Hepatocellular - metabolism | Mitochondrial DNA | Hepatoma | Health aspects | Apoptosis | Cytochrome | Leukemia | Hepatocellular carcinoma | Infections | Autophagy | Accumulation | Medical schools | Anticancer properties | Liver cancer | Mitochondria | Immunology | Surgery | Inhibition | Starvation | Rheumatology | Pharmacology | Exposure | Cytometry | Salinomycin | Antibiotics | Hepatocytes | Cell lines | In vivo methods and tests | Viability | Phagocytosis | Cancer
Journal Article
Molecular & Biochemical Parasitology, ISSN 0166-6851, 2006, Volume 149, Issue 1, pp. 86 - 98
Trisubstituted pyrrole inhibitors of the essential coccidian parasite cGMP dependent protein kinase (PKG) block parasite invasion and show efficacy against in... 
cGMP-dependent protein kinase | Toxoplasma | CK1 | CDPK | Eimeria | LIGHT-CHAIN KINASE | MOLECULAR CHARACTERIZATION | HOST-CELL INVASION | APICOMPLEXAN PARASITES | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROTOZOAN PARASITE | EIMERIA-TENELLA | PLASMODIUM-FALCIPARUM | CLINICAL-TRIALS | TOXOPLASMA-GONDII | GLIDING MOTILITY | PARASITOLOGY | Protein Kinases - metabolism | Skin - cytology | Coccidiostats - metabolism | Humans | Molecular Sequence Data | Eimeriida - drug effects | Male | Coccidiostats - isolation & purification | Recombinant Proteins | Toxoplasma - enzymology | Pyrimidines - metabolism | Cyclic GMP-Dependent Protein Kinases - antagonists & inhibitors | Fibroblasts | Casein Kinase I - antagonists & inhibitors | Calcium-Calmodulin-Dependent Protein Kinase Type 1 | Eimeria tenella - drug effects | Imidazoles - metabolism | Amino Acid Sequence | Pyrroles - metabolism | Eimeria tenella - enzymology | Imidazoles - pharmacology | Kidney - cytology | Epitopes | Protein Kinase Inhibitors - isolation & purification | Pyrimidines - pharmacology | Calcium-Calmodulin-Dependent Protein Kinases - antagonists & inhibitors | Pyrroles - pharmacology | Animals | Pyridines - metabolism | Casein Kinase I - metabolism | Coccidiostats - pharmacology | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Toxoplasma - drug effects | Eimeriida - enzymology | Protein Kinase Inhibitors - metabolism | Enzymes | Casein | Heterocyclic compounds | Analysis | Physiological aspects | Amino acids | Thiophene | Protein kinases | Cobalt | Protein binding
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 10/2015, Volume 59, Issue 10, pp. 6361 - 6374
We report on the in vitro effects of the bumped kinase inhibitor 1294 (BKI-1294) in cultures of virulent Neospora caninum isolates Nc-Liverpool (Nc-Liv) and... 
ANTIBODIES | T. GONDII | CDPK1 | PROTEIN-KINASE | C. PARVUM | SELECTIVE INHIBITORS | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | INFECTION | MICE | TACHYZOITES | CELL-CULTURES | Experimental Therapeutics
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