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Journal of Neuroscience, ISSN 0270-6474, 07/2001, Volume 21, Issue 13, pp. 4712 - 4720
The mammalian inner ear contains two sensory organs, the cochlea and vestibule. Their sensory neuroepithelia are characterized by a mosaic of hair cells and... 
Basic helix-loop-helix (bHLH) transcriptions factors | Hair cell differentiation | Math1 | Cochlea | Hes1 | Mouse mutant | Hes5 | Saccule | Utricle | cochlea | utricle | LOOP-HELIX FACTORS | ENHANCER | NEUROSCIENCES | DROSOPHILA | NEGATIVE REGULATOR | transcriptions factors | DEVELOPING NERVOUS-SYSTEM | saccule | mouse mutant | hair cell differentiation | NOTCH SIGNALING PATHWAY | DIFFERENTIATION | NEUROGENIC GENES | EXPRESSION | basic helix-loop-helix (bHLH) | Immunohistochemistry | Up-Regulation | Cochlea - embryology | Hair Cells, Auditory - metabolism | Transcription Factor HES-1 | Ear, Inner - embryology | Cell Count | Homeodomain Proteins - metabolism | RNA, Messenger - metabolism | DNA-Binding Proteins - metabolism | Cell Differentiation - genetics | In Situ Hybridization | Cochlea - metabolism | Mice, Mutant Strains | Repressor Proteins - metabolism | Basic Helix-Loop-Helix Transcription Factors | Ear, Inner - cytology | Repressor Proteins - genetics | Cochlea - cytology | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Homeodomain Proteins - genetics | Nerve Tissue Proteins - metabolism | Transcription Factors - metabolism | Homozygote | Ear, Inner - metabolism | Animals | Heterozygote | Mice | Crosses, Genetic | Hes gene | Index Medicus
Journal Article
Antioxidants & Redox Signaling, ISSN 1523-0864, 02/2012, Volume 16, Issue 3, pp. 263 - 274
Journal Article
Neurobiology of Aging, ISSN 0197-4580, 2006, Volume 28, Issue 10, pp. 1605 - 1612
Journal Article
Developmental Biology, ISSN 0012-1606, 09/2013, Volume 381, Issue 2, pp. 401 - 410
Journal Article
Neuroscience, ISSN 0306-4522, 2014, Volume 284, pp. 470 - 482
Highlights • Pre- and post-somatic segments of type I spiral ganglion neurons (SGNs) are unmyelinated in man. • Following hair cell loss and retrograde nerve... 
Neurology | spiral ganglion neurons | collagen IV | laminin-β2 | immunohistochemistry | human cochlea | non-myelinated Schwann cells | Immunohistochemistry | Laminin-β2 | Spiral ganglion neurons | Collagen IV | Non-myelinated Schwann cells | Human cochlea | SURVIVAL | NERVE | IMMUNOHISTOCHEMICAL LOCALIZATION | DORSAL-ROOT GANGLIA | ELECTRON-MICROSCOPY | laminin-beta 2 | NEUROSCIENCES | SATELLITE GLIAL-CELLS | HEARING-LOSS | BASAL LAMINA | CORTI LOSS | immuno-histochemistry | HUMAN INNER-EAR | Satellite Cells, Perineuronal - cytology | Neurons - pathology | Humans | Middle Aged | Male | Neurons - cytology | Satellite Cells, Perineuronal - metabolism | Basement Membrane - pathology | Spiral Ganglion - cytology | Schwann Cells - cytology | Spiral Ganglion - pathology | Adult | Female | Neurons - metabolism | Imaging, Three-Dimensional | Microscopy, Electron, Transmission | Microscopy, Electron, Scanning | Basement Membrane - cytology | Schwann Cells - pathology | Schwann Cells - metabolism | Spiral Ganglion - metabolism | Basement Membrane - metabolism | Collagen - metabolism | Microscopy, Confocal | Cochlear Implantation | Laminin - metabolism | Satellite Cells, Perineuronal - pathology | Deafness | Ganglion | Neurons | Analysis | Index Medicus | Cx43, connexin 43 | ECM, extracellular matrix | CI, cochlear implants | SGN, spiral ganglion neuron | BM, basement membrane | NMSC, non-myelinated Schwann cell | NIHL, noise-induced hearing loss | PBS, phosphate-buffered saline | SEM, scanning electron microscopy | IHC, immunohistochemistry | SGC, satellite glial cell | EDTA, ethylene-diamine-tetra-acetic acid | SG, spiral ganglion | type I ganglion cells, large afferent neurons innervating inner hair cell | Nav1.6, Na+-channels | TEM, transmission electron microscopy | LM, light microscopy | MBP, myelin basic protein | AIS, axonal initial segment | type II ganglion cells, small afferent neurons innervating outer hair cells | Basic Medicine | Neurosciences | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | Kirurgi | Clinical Medicine | Surgery | Medicinska och farmaceutiska grundvetenskaper | Neurovetenskaper
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 05/2003, Volume 23, Issue 10, pp. 4054 - 4065
Journal Article
Nature Communications, ISSN 2041-1723, 2017, Volume 8, Issue 1, pp. 15046 - 15046
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2008, Volume 105, Issue 48, pp. 18770 - 18775
Journal Article
Developmental Cell, ISSN 1534-5807, 02/2012, Volume 22, Issue 2, pp. 377 - 390
Inner-ear hair cell differentiation requires function, while , , and are coexpressed in sensory progenitors and mutations in these genes cause sensorineural... 
MATH1 | BRANCHIOOTORENAL BOR SYNDROME | GENE | MAMMALIAN INNER-EAR | DROSOPHILA-EYES-ABSENT | CRE RECOMBINASE | SIX1 | DEVELOPMENTAL BIOLOGY | MUTATIONS | ORGAN | CORTI | CELL BIOLOGY | Hair Cells, Auditory - metabolism | Phosphorylation | Immunoprecipitation | Homeodomain Proteins - metabolism | Protein Tyrosine Phosphatases - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Embryo, Mammalian - metabolism | Immunoenzyme Techniques | SOXB1 Transcription Factors - metabolism | Protein Tyrosine Phosphatases - genetics | Basic Helix-Loop-Helix Transcription Factors - metabolism | Chromatin Immunoprecipitation | SOXB1 Transcription Factors - genetics | Cochlea - metabolism | Gene Expression Regulation, Developmental | Cell Differentiation | Electrophoretic Mobility Shift Assay | Nuclear Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Basic Helix-Loop-Helix Transcription Factors - genetics | Electroporation | Nuclear Proteins - metabolism | Cochlea - cytology | Mutation - genetics | Blotting, Western | Homeodomain Proteins - genetics | Animals | Embryo, Mammalian - cytology | Mice | Proteins | Genes | Genetic transcription | Explants | Enhancers | Transcription | Eya1 protein | Hair cells | Stem cells | Cochlea | Mutation | Differentiation | Epithelium | Hearing loss | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2019, Volume 116, Issue 11, pp. 4999 - 5008
Journal Article
Nature Cell Biology, ISSN 1465-7392, 09/2013, Volume 15, Issue 9, pp. 1107 - 1115
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2013, Volume 110, Issue 18, pp. 7300 - 7305
The ectodermal dysplasias are a group of inherited autosomal dominant syndromes associated with heterozygous mutations in the Tumor Protein p63 (TRP63) gene.... 
Deafness | Developmental biology | Hair cells | Cochlea | Organ of corti | Outer hair cells | Mice | Gene expression regulation | Embryos | Genetic mutation | Cell death | Epidermis | p53 family | APOPTOSIS | cell death | MULTIDISCIPLINARY SCIENCES | EEC-SYNDROME | P53 HOMOLOG | HAIR-CELLS | GENE | MAMMALIAN INNER-EAR | EPIDERMAL DEVELOPMENT | DIFFERENTIATION | MUTATIONS | MATH1 EXPRESSION | epidermis | Cochlea - embryology | Receptors, Notch - metabolism | Humans | Phosphoproteins - metabolism | Promoter Regions, Genetic - genetics | Deafness - embryology | Proto-Oncogene Proteins c-bcl-2 - metabolism | Protein Isoforms - metabolism | Basic Helix-Loop-Helix Transcription Factors - metabolism | Hearing Loss, Sensorineural - embryology | Apoptosis Regulatory Proteins - deficiency | Cochlea - metabolism | Tumor Suppressor Proteins - deficiency | Ectodermal Dysplasia - pathology | Repressor Proteins - metabolism | Tumor Suppressor Proteins - metabolism | Hearing Loss, Sensorineural - metabolism | Signal Transduction | Ectodermal Dysplasia - embryology | Mice, Inbred C57BL | Hearing Loss, Sensorineural - pathology | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Proto-Oncogene Proteins c-bcl-2 - deficiency | Deafness - pathology | Animals | Trans-Activators - deficiency | Deafness - metabolism | Cochlea - pathology | Phosphoproteins - deficiency | Trans-Activators - metabolism | Ectodermal Dysplasia - genetics | Gene mutations | Physiological aspects | Genetic aspects | Research | Tumor proteins | Health aspects | Proteins | Cochlear implants | Morphology