Articles

UofT Libraries is getting a new library services platform in January 2021.
Learn more about the change.

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (1218) 1218
Book Chapter (26) 26
Newspaper Article (10) 10
Newsletter (9) 9
Dissertation (5) 5
Magazine Article (4) 4
Transcript (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (721) 721
science & technology (663) 663
life sciences & biomedicine (636) 636
codeine (504) 504
male (481) 481
animals (373) 373
codeine - metabolism (346) 346
biological and medical sciences (344) 344
female (339) 339
medical sciences (306) 306
pharmacology & pharmacy (255) 255
adult (253) 253
morphine (245) 245
rats (220) 220
pharmacology. drug treatments (215) 215
codeine - pharmacology (213) 213
codeine - analogs & derivatives (193) 193
analgesics (171) 171
codeine - pharmacokinetics (150) 150
codeine - administration & dosage (144) 144
morphine - metabolism (144) 144
toxicology (136) 136
middle aged (124) 124
narcotics (117) 117
codeine - adverse effects (114) 114
codeine - therapeutic use (110) 110
chemistry (108) 108
neuropharmacology (102) 102
abridged index medicus (101) 101
metabolites (99) 99
physical sciences (98) 98
analysis (96) 96
metabolism (95) 95
pharmacogenetics (92) 92
opioids (90) 90
pain (89) 89
codeine - urine (88) 88
research (87) 87
codeine - analysis (86) 86
codeine - blood (86) 86
administration, oral (85) 85
time factors (84) 84
analgesics, opioid - therapeutic use (82) 82
analgesics, opioid - pharmacokinetics (79) 79
chemistry, analytical (77) 77
drugs (76) 76
analgesics, opioid - adverse effects (75) 75
kinetics (75) 75
pharmacology (74) 74
cytochrome p-450 cyp2d6 - genetics (72) 72
pain - drug therapy (72) 72
aged (71) 71
in vitro techniques (71) 71
analgesics, opioid - pharmacology (70) 70
gas chromatography-mass spectrometry (70) 70
child (69) 69
mice (68) 68
morphine - pharmacology (68) 68
analgesics, opioid - metabolism (67) 67
tramadol (66) 66
morphine - blood (65) 65
pediatrics (64) 64
pharmacokinetics (64) 64
drug interactions (63) 63
dose-response relationship, drug (62) 62
adolescent (61) 61
analgesia (61) 61
analgesics, opioid - administration & dosage (57) 57
cytochrome p-450 cyp2d6 - metabolism (57) 57
morphine - urine (57) 57
central nervous system depressants (56) 56
morphine - analysis (55) 55
biotransformation (54) 54
health aspects (54) 54
biochemistry & molecular biology (53) 53
genotype (52) 52
heroin (52) 52
brain - metabolism (50) 50
chromatography, high pressure liquid (50) 50
oxycodone (50) 50
drug addictions (49) 49
pain management (49) 49
phenotype (48) 48
rabbits (48) 48
substance abuse detection - methods (48) 48
fundamental and applied biological sciences. psychology (47) 47
general pharmacology (46) 46
urine (46) 46
mass spectrometry (45) 45
codeine - chemistry (44) 44
cyp2d6 (44) 44
drug abuse (44) 44
guinea pigs (44) 44
liver - metabolism (44) 44
drug combinations (43) 43
neurosciences & neurology (43) 43
care and treatment (42) 42
cytochrome p450 (42) 42
enzymes (42) 42
double-blind method (41) 41
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (1222) 1222
German (29) 29
Japanese (12) 12
Russian (6) 6
Chinese (4) 4
Spanish (4) 4
French (3) 3
Czech (2) 2
Norwegian (2) 2
Portuguese (2) 2
Bulgarian (1) 1
Dutch (1) 1
Italian (1) 1
Polish (1) 1
Swedish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Comparative Metabolic Capabilities and Inhibitory Profiles of CYP2D6.1, CYP2D6.10, and CYP2D6.17
by Hongwu Shen and Minxia M. He and Houfu Liu and Steven A. Wrighton and Li Wang and Bin Guo and Chuan Li
Drug metabolism and disposition, ISSN 0090-9556, 08/2007, Volume 35, Issue 8, pp. 1292 - 1300
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Biological and medical sciences | Pharmacology. Drug treatments | Medical sciences | Microsomes - metabolism | Quinidine - chemistry | Tramadol - chemistry | Humans | Dextromethorphan - metabolism | Imipramine - chemistry | Propylamines - pharmacokinetics | Codeine - chemistry | Debrisoquin - metabolism | Enzyme Inhibitors - chemistry | Fluoxetine - analogs & derivatives | Quinidine - pharmacokinetics | Propylamines - chemistry | Cocaine - chemistry | Cytochrome P-450 CYP2D6 - genetics | Recombinant Proteins - antagonists & inhibitors | Debrisoquin - chemistry | Enzyme Inhibitors - metabolism | Hydroxylation | Cocaine - pharmacokinetics | Ethanolamines - chemistry | Tramadol - pharmacokinetics | Nortriptyline - metabolism | Fluoxetine - metabolism | Cytochrome P-450 CYP2D6 - metabolism | Kinetics | Thioridazine - metabolism | Cytochrome P-450 CYP2D6 Inhibitors | Nortriptyline - chemistry | Cocaine - metabolism | Fluoxetine - pharmacokinetics | Debrisoquin - pharmacokinetics | Ethanolamines - pharmacokinetics | Codeine - metabolism | Enzyme Inhibitors - pharmacokinetics | Thioridazine - pharmacokinetics | Atomoxetine Hydrochloride | Codeine - pharmacokinetics | Thioridazine - chemistry | Dextromethorphan - pharmacokinetics | Molecular Structure | Quinidine - metabolism | Recombinant Proteins - metabolism | Imipramine - pharmacokinetics | Nortriptyline - pharmacokinetics | Dextromethorphan - chemistry | Fluoxetine - chemistry | Tramadol - metabolism | Ethanolamines - metabolism | Imipramine - metabolism | Polymorphism, Single Nucleotide | Propylamines - metabolism | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text A microbial biomanufacturing platform for natural and semisynthetic opioids
by Thodey, Kate and Thodey, Kate and Galanie, Stephanie and Smolke, Christina D
Nature chemical biology, ISSN 1552-4450, 10/2014, Volume 10, Issue 10, pp. 837 - 844
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Hydromorphone - metabolism | Pseudomonas putida - genetics | Gene Expression | Metabolic Engineering - methods | Codeine - biosynthesis | Saccharomyces cerevisiae - genetics | Bacterial Proteins - genetics | Morphine - biosynthesis | Gene Dosage | Papaver - genetics | Hydrocodone - metabolism | Saccharomyces cerevisiae - metabolism | Plant Proteins - genetics | Pseudomonas putida - metabolism | Thebaine - metabolism | Hydrocodone - analogs & derivatives | Metabolic Networks and Pathways | Bacterial Proteins - metabolism | Plant Proteins - metabolism | Papaver - metabolism | Oxycodone - metabolism | Biosynthesis | Yeast | Narcotics | Fermentation | Pharmaceutical sciences | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Codeine, Ultrarapid-Metabolism Genotype, and Postoperative Death
by Lauwers, Albert E and Koren, Gideon and Phillips, Michael S and Ciszkowski, Catherine and Madadi, Parvaz
The New England journal of medicine, ISSN 0028-4793, 08/2009, Volume 361, Issue 8, pp. 827 - 828
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Cytochrome P-450 CYP2D6 - genetics | Analgesics, Opioid - blood | Humans | Bronchopneumonia - complications | Child, Preschool | Genotype | Male | Morphine - blood | Adenoidectomy | Codeine - administration & dosage | Codeine - blood | Codeine - metabolism | Analgesics, Opioid - administration & dosage | Tonsillectomy | Fatal Outcome | Cytochrome P-450 CYP2D6 - metabolism | Sleep Apnea Syndromes - surgery | Analgesics, Opioid - metabolism | Postoperative Complications | Sleep disorders | Sleep apnea | Mass spectrometry | Carbon dioxide
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Total biosynthesis of opiates by stepwise fermentation using engineered Escherichia coli
by Nakagawa, Akira and Matsumura, Eitaro and Koyanagi, Takashi and Katayama, Takane and Kawano, Noriaki and Yoshimatsu, Kayo and Yamamoto, Kenji and Kumagai, Hidehiko and Sato, Fumihiko and Minami, Hiromichi
Nature communications, ISSN 2041-1723, 02/2016, Volume 7, Issue 1, pp. 10390 - 10390
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Coptis - genetics | Codeine - biosynthesis | Oxidoreductases - genetics | Methyltransferases - metabolism | Methyltransferases - genetics | Morphine - biosynthesis | Papaver - genetics | Fermentation | Acetyltransferases - genetics | Hydrocodone - metabolism | Thebaine - metabolism | Benzylisoquinolines - metabolism | Glycerol - metabolism | Escherichia coli - genetics | Escherichia coli - metabolism | Organisms, Genetically Modified - metabolism | Analgesics, Opioid - metabolism | Organisms, Genetically Modified - genetics | Oxycodone - metabolism | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Codeine Intoxication Associated with Ultrarapid CYP2D6 Metabolism
by Gasche, Yvan and Daali, Youssef and Fathi, Marc and Chiappe, Alberto and Cottini, Silvia and Dayer, Pierre and Desmeules, Jules
The New England journal of medicine, ISSN 0028-4793, 12/2004, Volume 351, Issue 27, pp. 2827 - 2831
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Biological and medical sciences | General aspects | Medical sciences | Dextromethorphan - therapeutic use | Antitussive Agents - poisoning | Cough - drug therapy | Cytochrome P-450 CYP3A | Humans | Middle Aged | Cytochrome P-450 Enzyme System - metabolism | Dextromethorphan - metabolism | Male | Codeine - administration & dosage | Codeine - metabolism | Lung Diseases, Fungal - drug therapy | Antitussive Agents - metabolism | Codeine - poisoning | Cytochrome P-450 CYP2D6 - genetics | Analgesics, Opioid - poisoning | Genotype | Cough - etiology | Phenotype | Antitussive Agents - administration & dosage | Pneumonia - drug therapy | Analgesics, Opioid - administration & dosage | Cytochrome P-450 CYP2D6 - metabolism | Cytochrome P-450 Enzyme System - genetics | Pneumonia - complications | Analgesics, Opioid - metabolism | Methylation | Pneumonia | Dosage and administration | Drug therapy | Bacterial pneumonia | Cough | Codeine | Index Medicus | Abridged Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text In vitro metabolism of desomorphine
by Winborn, Jessica and Haines, Donovan and Kerrigan, Sarah
Forensic science international, ISSN 0379-0738, 08/2018, Volume 289, pp. 140 - 149
Krokodil | Metabolism | CYP450 | Isoenzymes | Desomorphine | Life Sciences & Biomedicine | Medicine, Legal | Legal Medicine | Science & Technology | Street Drugs - pharmacokinetics | Biotransformation | Humans | Mass Spectrometry | Codeine - pharmacokinetics | Chromatography, Liquid | Codeine - analogs & derivatives | Cytochrome P-450 Enzyme System | Glucuronosyltransferase | Usage | Toxicity testing | Drug metabolism | Research | Mass spectrometry | In vitro | Cytochrome | Awards & honors | Enzymes | Narcotics | Cytochrome P450 | Mass spectroscopy | Pharmacology | Liquid chromatography | Identification | Quadrupoles | Acids | Metabolites | Opioids | Uridine | Heroin | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Complete biosynthesis of opioids in yeast
by Stephanie Galanie and Kate Thodey and Isis J. Trenchard and Maria Filsinger Interrante and Christina D. Smolke
Science (American Association for the Advancement of Science), ISSN 0036-8075, 9/2015, Volume 349, Issue 6252, pp. 1095 - 1100
REPORTS | Genetic Engineering - methods | Morphinans - chemistry | Thebaine - chemistry | Carbohydrate Metabolism | Papaver - genetics | Hydrocodone - chemistry | Hydrocodone - metabolism | Thebaine - metabolism | Animals | Biosynthetic Pathways - genetics | Morphinans - metabolism | Benzylisoquinolines - metabolism | Codeine - metabolism | Papaver - enzymology | Saccharomyces cerevisiae - enzymology | Physiological aspects | Biosynthesis | Yeast fungi | Identification and classification | Opioids | Palliative care | Yeast | Pain management | Index Medicus | Drugs | Enzymes | Poppies | Narcotics | Bacteria | Optimization
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Pharmacogenetics affects dosing, efficacy, and toxicity of cytochrome P450–metabolized drugs
by Rogers, Janyce F and Nafziger, Anne N and Bertino, Joseph S
2002, Volume 113, Issue 9, 5
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Biological and medical sciences | Medical sciences | General pharmacology | Pharmacology. Drug treatments | Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions | Cytochrome P-450 CYP2C9 | Antidepressive Agents, Tricyclic - metabolism | Omeprazole - metabolism | Pharmacogenetics | Diazepam - metabolism | Humans | Warfarin - metabolism | Cytochrome P-450 Enzyme System - metabolism | Genotype | Mixed Function Oxygenases - metabolism | Anti-Arrhythmia Agents - metabolism | Glipizide - metabolism | Aryl Hydrocarbon Hydroxylases - metabolism | Phenotype | Codeine - metabolism | Cytochrome P-450 CYP2C19 | Cytochrome P-450 CYP2D6 - metabolism | Phenytoin - metabolism | Drug metabolism | Genetic aspects | Health aspects | Genetic polymorphisms | Cytochrome P-450 | Enzymes | Genetics | Pharmacology | Pharmaceuticals | Index Medicus | Abridged Index Medicus
Book Review
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Desomorphine (Krokodil): An overview of its chemistry, pharmacology, metabolism, toxicology and analysis
by Florez, Diego Hernando Ângulo and dos Santos Moreira, Ana Maria and da Silva, Pedro Rafael and Brandão, Ricardo and Borges, Marcella Matos Cordeiro and de Santana, Fernando José Malagueño and Borges, Keyller Bastos
Drug and alcohol dependence, ISSN 0376-8716, 2017, Volume 173, pp. 59 - 68
Psychiatry | Toxicology | Pharmacology | Krokodil | Analysis | Desomorphine | Life Sciences & Biomedicine | Substance Abuse | Science & Technology | Analgesics, Opioid - toxicity | Street Drugs - pharmacokinetics | Humans | Codeine - adverse effects | Analgesics, Opioid - pharmacology | Codeine - pharmacology | Street Drugs - adverse effects | Infection - chemically induced | Analgesics, Opioid - adverse effects | Analgesics, Opioid - pharmacokinetics | Codeine - pharmacokinetics | Codeine - toxicity | Opioid-Related Disorders | Behavior, Addictive | Street Drugs - toxicity | Codeine - analogs & derivatives | Street Drugs - pharmacology | Physiological aspects | Morphine | Usage | Metabolites | Drugs | Measurement | Illegal | Forensic engineering | Medical diagnosis | Literature reviews | Addicts | Opioids | Bones | Chemical agents | Public health | Consumption | Death & dying | Forensic science | Chemical reactions | Hazards | Metabolism | Addictions | Codeine | Chemistry | Side effects | Addiction | Forensic toxicology | Contaminants | Action control | Skin | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Toxicokinetics of drugs of abuse: Current knowledge of the isoenzymes involved in the human metabolism of tetrahydrocannabinol, cocaine, heroin, morphine, and codeine
by Maurer, Hans H and Sauer, Christoph and Theobald, Denis S
Therapeutic drug monitoring, ISSN 0163-4356, 06/2006, Volume 28, Issue 3, pp. 447 - 453
Toxicokinetics | Morphine | Cocaine | Drugs of abuse | Metabolism | Tetrahydrocannabinol | Heroin | Codeine | Pharmacology & Pharmacy | Toxicology | Life Sciences & Biomedicine | Medical Laboratory Technology | Science & Technology | Drug addictions | Biological and medical sciences | Medical sciences | Heroin - toxicity | Substance-Related Disorders - metabolism | Heroin - pharmacokinetics | Psychotropic Drugs - pharmacokinetics | Street Drugs - pharmacokinetics | Humans | Substance-Related Disorders - enzymology | Morphine - toxicity | Cocaine - pharmacokinetics | Dronabinol - pharmacokinetics | Cocaine - toxicity | Isoenzymes - metabolism | Morphine - pharmacokinetics | Codeine - pharmacokinetics | Codeine - toxicity | Narcotics - pharmacokinetics | Psychotropic Drugs - toxicity | Street Drugs - toxicity | Narcotics - toxicity | Dronabinol - toxicity | Drug abuse | Narcotics | Drug testing | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Absorption, distribution, metabolism and excretion pharmacogenomics of drugs of abuse
by Meyer, Markus R and Maurer, Hans H
Pharmacogenomics, ISSN 1462-2416, 02/2011, Volume 12, Issue 2, pp. 215 - 233
anesthetic | nicotine | hallucinogen | pharmacogenomics | drug of abuse | opioid | transporter | isoenzyme | metabolism | human | cognitive enhancer | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Hallucinogens - pharmacokinetics | Analgesics, Opioid - toxicity | Pharmacogenetics | Hallucinogens - toxicity | Isoenzymes - genetics | Street Drugs - pharmacokinetics | Humans | Nootropic Agents - pharmacokinetics | Nicotine - toxicity | Nootropic Agents - toxicity | Tissue Distribution | Absorption | Nicotine - metabolism | Analgesics, Opioid - pharmacokinetics | Street Drugs - toxicity | salvinorin A | Drug abuse | Cognitive ability | Methadone | reductase | Opioids | fentanyl | Drug metabolism | oxycodone | esterase | Propofol | Xenobiotics | Genotypes | Heroin | Excretion | Isoenzymes | modafinil |