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1. Full Text Ischaemia-reperfusion injury in liver transplantation-from bench to bedside
by Zhai, Yuan and Petrowsky, Henrik and Hong, Johnny C and Busuttil, Ronald W and Kupiec-Weglinski, Jerzy W
Nature Reviews Gastroenterology and Hepatology, ISSN 1759-5045, 02/2013, Volume 10, Issue 2, pp. 79 - 89
Ischaemia-reperfusion injury (IRI in the liver, a major complication of haemorrhagic shock, resection and transplantation, is a dynamic process that involves... 
IMMUNE-RESPONSE | SELECTIN GLYCOPROTEIN LIGAND-1 | ORGAN PRESERVATION | INFLAMMATORY RESPONSES | COLD ISCHEMIA/REPERFUSION | MOLECULAR-PATTERN MOLECULES | T-CELL | GASTROENTEROLOGY & HEPATOLOGY | HEPATIC ISCHEMIA/REPERFUSION INJURY | ENDOGENOUS LIGANDS | TOLL-LIKE-RECEPTOR | Adaptive Immunity - physiology | Liver - blood supply | Animals | Immunity, Innate - physiology | Swine | Humans | Reperfusion Injury - physiopathology | Models, Animal | Signal Transduction - physiology | Liver - surgery | Liver - physiopathology | Liver Transplantation - physiology | Complications and side effects | Transplantation | Research | Liver | Reperfusion injury | Risk factors
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2. Prolonged Cold Ischemia Induces Necroptotic Cell Death in Ischemia-Reperfusion Injury and Contributes to Primary Graft Dysfunction after Lung Transplantation
by Wang, X and O'Brien, ME and Yu, JY and Xu, C and Zhang, Q and Lu, SJ and Liang, LF and An, XJ and McDyer, JF and Mallampalli, RK
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, ISSN 1044-1549, 08/2019, Volume 61, Issue 2, pp. 244 - 256
Primary graft dysfunction (PGD) is a major cause of morbidity and mortality after lung transplantation. Ischemia-reperfusion injury (IRI) is a key event that... 
RISK-FACTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CONSENSUS GROUP STATEMENT | ISHLT WORKING GROUP | reperfusion injury | MECHANISMS | SOCIETY | CELL BIOLOGY | HEART | RESPIRATORY SYSTEM | MOUSE MODEL | lung transplantation | BRAIN-DEATH | primary graft dysfunction | necroptosis | Thoracic surgery | Animal models | Cold | Transplants & implants | Syngeneic grafts | Lung transplantation | Brain death | Inflammation | Kinases | Hemorrhage | Morbidity | Arteries | Risk factors | Proteins | Medicine | Reperfusion | Ischemia | Lungs | Protein kinase | Cell death | Inbreeding | Apoptosis
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3. Full Text A mouse model of renal ischemia-reperfusion injury solely induced by cold ischemia
by Wei, J and Wang, YL and Zhang, J and Wang, L and Fu, LY and Cha, BJ and Buggs, J and Liu, RS
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, ISSN 1931-857X, 09/2019, Volume 317, Issue 3, pp. E616 - E622
Transplanted kidneys usually experience several episodes of ischemia, including cold ischemia during allograft storage in preservation solution. However,... 
SURVIVAL | STORAGE | PHYSIOLOGY | DELAYED GRAFT FUNCTION | cold ischemia | kidney transplantation | TIME | TRANSPLANT RECIPIENTS | PRESERVATION SOLUTIONS | PATHOPHYSIOLOGY | ischemia-reperfusion injury | IMPACT | KIDNEY-TRANSPLANTATION | UROLOGY & NEPHROLOGY | PERFUSION
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4. Full Text Mesenchymal stem cells attenuate ischemia–reperfusion injury after prolonged cold ischemia in a mouse model of lung transplantation: a preliminary study
by Watanabe, Tatsuaki and Hoshikawa, Yasushi and Ishibashi, Naoya and Suzuki, Hirotoshi and Notsuda, Hirotsugu and Watanabe, Yui and Noda, Masafumi and Kanehira, Masahiko and Ohkouchi, Shinya and Kondo, Takashi and Okada, Yoshinori
Surgery Today, ISSN 0941-1291, 4/2017, Volume 47, Issue 4, pp. 425 - 431
Mesenchymal stem cells (MSCs) suppress inflammation and immune responses. We conducted this study to find out if MSCs attenuate ischemia–reperfusion injury in... 
Ischemia–reperfusion injury | Medicine & Public Health | Surgical Oncology | Surgery | Lung transplantation | Mesenchymal stem cells | SURGERY | INTERNATIONAL-SOCIETY | BONE-MARROW | RESOLUTION | RAT MODEL | ORGAN-TRANSPLANTATION | PRESERVATION | Ischemia-reperfusion injury | INFLAMMATION | MICE | STROMAL CELLS | EXPRESSION | Reperfusion Injury - etiology | Reperfusion Injury - therapy | Mice, Inbred C57BL | Ischemia - therapy | Male | Pulmonary Artery | Cold Temperature - adverse effects | Mesenchymal Stem Cell Transplantation - methods | Lung Transplantation | Animals | Mesenchymal Stromal Cells | Time Factors | Models, Animal | Lung - blood supply | Ischemia - etiology | Dextran | Transplantation | Analysis | Reperfusion injury | Stem cells | Index Medicus
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5. Hypothermia and cerebral ischemia
: mechanisms and clinical applications
by Maier, Carolina M and Steinberg, Gary K
2004, ISBN 089603660X, x, 188
Brain | Cerebral ischemia | Brain Ischemia | Treatment | Cold | Brain Injuries | Cerebrovascular Accident | therapy | Hypothermia, Induced | Effect of cold on | Brain damage | Therapeutic use
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6. Full Text Liver Ischemia and Reperfusion Injury: New Insights into Mechanisms of Innate—Adaptive Immune‐Mediated Tissue Inflammation
by Zhai, Y and Busuttil, R. W and Kupiec‐Weglinski, J. W
American Journal of Transplantation, ISSN 1600-6135, 08/2011, Volume 11, Issue 8, pp. 1563 - 1569
Ischemia and reperfusion injury (IRI) is a dynamic process that involves two distinctive yet interrelated phases of ischemic organ damage and... 
toll‐like receptors | Innate immunity | T cells | ischemia/reperfusion injury | liver | neutrophils | toll-like receptors | SURGERY | ACTIVATION | DENDRITIC CELLS | RECEPTOR | HEPATIC ISCHEMIA/REPERFUSION INJURY | TRANSPLANTATION | PROTECTS | DANGER SIGNALS | COLD ISCHEMIA | MOUSE MODEL | T-CELLS | Adaptive Immunity | Liver - blood supply | Reperfusion Injury | Humans | Toll-Like Receptors - physiology | Inflammation - immunology | Interleukin-10 - physiology | Liver diseases | Liver | Transplantation of organs, tissues, etc | Organ transplant recipients | Inflammation | Health aspects | Reperfusion injury | innate immunity | Neutrophils | Toll-like receptors | reperfusion injury | ischemia
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7. Full Text Autophagy and liver ischemia-reperfusion injury
by Cursio, Raffaele and Colosetti, Pascal and Gugenheim, Jean
BioMed Research International, ISSN 2314-6133, 2015, Volume 2015, pp. 417590 - 16
Liver ischemia-reperfusion (I-R) injury occurs during liver resection, liver transplantation, and hemorrhagic shock. The main mode of liver cell death after... 
RAT-LIVER | IMPAIRED AUTOPHAGY | MEDICINE, RESEARCH & EXPERIMENTAL | GROUP BOX 1 | MITOCHONDRIAL PERMEABILITY TRANSITION | ACTIVATED RECEPTOR-GAMMA | MEDIATED AUTOPHAGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | PROTEIN-KINASE | ENDOTHELIAL-CELLS | COLD PRESERVATION | HEPATIC ISCHEMIA/REPERFUSION INJURY | Liver - pathology | Autophagy - physiology | Animals | Reperfusion Injury - pathology | Humans | Liver Diseases - pathology | Autophagy (Cytology) | Development and progression | Liver diseases | Health aspects | Reperfusion injury | Proteins | Oxidative stress | Transplants & implants | Ischemia | Cold | Liver | Rodents | Gangrene | Homeostasis | Metabolism | Autophagy | Apoptosis | Review
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8. Full Text "Zero ischemia" partial nephrectomy: Novel laparoscopic and robotic technique
by Gill, Inderbir S and Eisenberg, Manuel S and Aron, Monish and Berger, Andre and Ukimura, Osamu and Patil, Mukul B and Campese, Vito and Thangathurai, Duraiyah and Desai, Mihir M
European Urology, ISSN 0302-2838, 01/2011, Volume 59, Issue 1, pp. 128 - 134
Background: Ischemic injury impacts renal function outcomes following partial nephrectomy. Efforts to minimize, better yet, eliminate renal ischemia are... 
Partial nephrectomy | Ischemia | Kidney tumor | Robotic | Unclamped | Kidney mass | Laparoscopy | HYPOTHERMIA | TIME | BLOOD-FLOW | RENAL-CELL CARCINOMA | UROLOGY & NEPHROLOGY | EXPERIENCE | NEPHRON-SPARING SURGERY | KIDNEY | CONTROLLED HYPOTENSIVE ANESTHESIA | Blood Pressure | Renal Veins - surgery | Prospective Studies | Ultrasonography, Doppler, Color | Microdissection | Humans | Middle Aged | Male | Tomography, X-Ray Computed | Cold Ischemia | Kidney Neoplasms - blood | Nephrectomy - methods | Robotics | Kidney Neoplasms - diagnosis | Kidney Neoplasms - surgery | Renal Artery - physiopathology | Kidney Neoplasms - physiopathology | Time Factors | Adult | Glomerular Filtration Rate | Constriction | Treatment Outcome | Biomarkers - blood | Renal Veins - physiopathology | Warm Ischemia | Surgery, Computer-Assisted | Creatinine - blood | Aged | Los Angeles | Renal Artery - surgery | Vasodilator Agents - administration & dosage | Laparoscopic surgery | Methods
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9. Full Text Assessing the Impact of Ischaemia Time During Partial Nephrectomy
by Becker, Frank and Van Poppel, Hein and Hakenberg, Oliver W and Stief, Christian and Gill, Inderbir and Guazzoni, Giorgio and Montorsi, Francesco and Russo, Paul and Stöckle, Michael
European Urology, ISSN 0302-2838, 2009, Volume 56, Issue 4, pp. 625 - 635
Abstract Context The impact of applying renal ischaemia during nephron-sparing surgery to avoid renal damage in the treated kidney has gained importance in... 
Urology | Renal tumours | Partial nephrectomy | Ischemia | Nephron-sparing surgery | Renal cell carcinoma | Kidney function | LONG-TERM | NORMAL CONTRALATERAL KIDNEY | WARM ISCHEMIA | LAPAROSCOPIC PARTIAL NEPHRECTOMY | RENAL-CELL CARCINOMA | RADICAL NEPHRECTOMY | COLD ISCHEMIA | UROLOGY & NEPHROLOGY | QUALITY-OF-LIFE | CHRONIC KIDNEY-DISEASE | Kidney Neoplasms - surgery | Carcinoma, Renal Cell - surgery | Cold Ischemia | Humans | Warm Ischemia | Nephrectomy - methods | Hospitals
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10. Full Text Intra‐Abdominal Cooling System Limits Ischemia–Reperfusion Injury During Robot‐Assisted Renal Transplantation
by Meier, R. P. H and Piller, V and Hagen, M. E and Joliat, C and Buchs, J.‐B and Nastasi, A and Ruttimann, R and Buchs, N. C and Moll, S and Vallée, J.‐P and Lazeyras, F and Morel, P and Bühler, L
American Journal of Transplantation, ISSN 1600-6135, 01/2018, Volume 18, Issue 1, pp. 53 - 62
Robot‐assisted kidney transplantation is feasible; however, concerns have been raised about possible increases in warm ischemia times. We describe a novel... 
surgical technique | translational research/science | pathology/histopathology | kidney transplantation/nephrology | autotransplantation | ischemia reperfusion injury (IRI) | basic (laboratory) research/science | kidney failure/injury | organ perfusion and preservation | SURGERY | basic (laboratory) research | pathology | kidney transplantation | Y GASTRIC BYPASS | histopathology | kidney failure | MODEL | DONOR NEPHRECTOMY | TRANSPLANTATION | nephrology | KIDNEY-TRANSPLANTATION | science | PROSTATECTOMY | translational research | EXPERIENCE | injury | OUTCOMES | Cold Temperature | Male | Kidney Transplantation | Laparoscopy | Reperfusion Injury - surgery | Animals | Hypothermia, Induced - instrumentation | Reperfusion Injury - prevention & control | Abdominal Cavity | Nephrectomy | Swine | Robotics - methods | Tissue Survival | Prevention | Transplantation | Kidneys | Reperfusion injury | Robots | Temperature requirements | Neuroimaging | Cooling | Nuclear magnetic resonance--NMR | Transplants & implants | Syngeneic grafts | Anastomosis | Robotics | Abdomen | Reperfusion | Magnetic resonance imaging | Ischemia | Renal cortex | Kidney transplantation | Original
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11. Full Text Ischaemia-reperfusion injury: A major protagonist in kidney transplantation
by Ponticelli, Claudio
Nephrology Dialysis Transplantation, ISSN 0931-0509, 2014, Volume 29, Issue 6, pp. 1134 - 1140
Ischaemia-reperfusion injury (IRI) is a frequent event in kidney transplantation, particularly when the kidney comes from a deceased donor. The brain death is... 
acute kidney injury | dendritic cells | ischaemia reperfusion | innate immunity | delayed graft function | SURVIVAL | COMPLEMENT | RENAL FIBROGENESIS | TRANSPLANTATION | ALLOGRAFT FUNCTION | REJECTION | DISEASE | DONOR BRAIN-DEATH | UROLOGY & NEPHROLOGY | OUTCOMES | SUPEROXIDE-DISMUTASE | Inflammation - pathology | Reperfusion Injury - etiology | Reperfusion Injury - pathology | Humans | Toll-Like Receptors - immunology | Kidney - immunology | Acetylcysteine | Dendritic Cells - physiology | Male | Complement C5a - physiology | Delayed Graft Function - physiopathology | Cold Ischemia | Antioxidants - therapeutic use | Animals | Arginine | Immunity, Innate - physiology | Reperfusion Injury - immunology | Warm Ischemia | Reperfusion Injury - physiopathology | Graft Survival - physiology | Delayed Graft Function - immunology | Tissue Donors | Kidney - physiopathology | Kidney Transplantation - adverse effects
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12. Full Text Surgical Renal Ischemia: A Contemporary Overview
by Simmons, Matthew N and Schreiber, Martin J and Gill, Inderbir S
Journal of Urology, The, ISSN 0022-5347, 2008, Volume 180, Issue 1, pp. 19 - 30
Purpose Partial nephrectomy is being increasingly performed to treat renal cell carcinoma. Because warm ischemia is induced during many open and laparoscopic... 
Urology | kidney | warm ischemia | nephrectomy | kidney diseases | cold ischemia | SURGERY | SOLITARY KIDNEY | OXYGEN DELIVERY | LAPAROSCOPIC PARTIAL NEPHRECTOMY | RATS | ISCHEMIA/REPERFUSION-INJURY | FAILURE | RECOVERY | UROLOGY & NEPHROLOGY | CHRONIC KIDNEY-DISEASE | Animals | Cold Ischemia - adverse effects | Kidney Diseases - etiology | Kidney Diseases - prevention & control | Warm Ischemia - adverse effects | Humans | Aneurysms | Urea | Chronic kidney failure | Ischemia | Muscle proteins | Adenosine triphosphate
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13. Full Text Liver grafts from CD39‐overexpressing rodents are protected from ischemia reperfusion injury due to reduced numbers of resident CD4+ T cells
by Pommey, Sandra and Lu, Bo and McRae, Jennifer and Stagg, John and Hill, Prue and Salvaris, Evelyn and Robson, Simon C and d'Apice, Anthony J.F and Cowan, Peter J and Dwyer, Karen M
Hepatology, ISSN 0270-9139, 04/2013, Volume 57, Issue 4, pp. 1597 - 1606
Ischemia‐reperfusion injury (IRI) is a major limiting event for successful liver transplantation, and CD4+ T cells and invariant natural killer T (iNKT) cells... 
IMMUNE SUPPRESSION | HUMAN CD39 | IFN-GAMMA | INFLAMMATION | ADENOSINE | MICE | GASTROENTEROLOGY & HEPATOLOGY | HEPATIC ISCHEMIA/REPERFUSION INJURY | A(2A) RECEPTOR ACTIVATION | TRANSPLANTATION | LYMPHOCYTES | Up-Regulation | Male | Alanine Transaminase - blood | Killer Cells, Natural - pathology | CD4-Positive T-Lymphocytes - pathology | Lymphopenia - pathology | Antigens, CD - genetics | T-Lymphocytes, Regulatory - pathology | Antigens, CD - metabolism | CD4-Positive T-Lymphocytes - immunology | Interleukin-6 - blood | Reperfusion Injury - metabolism | Disease Models, Animal | Reperfusion Injury - pathology | Liver Transplantation - pathology | Mice, Inbred C57BL | Apyrase - metabolism | Mice, Transgenic | Mice, Knockout | Animals | Reperfusion Injury - prevention & control | Apyrase - genetics | Mice | Liver Transplantation - immunology | Lymphopenia - genetics | Transplants & implants | Ischemia | Cold | Lymphocytes | Liver | Rodents | Hepatology
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