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Biomaterials, ISSN 0142-9612, 2011, Volume 33, Issue 9, pp. 2629 - 2641
Abstract Micro/nanotopographical modification of biomaterials constitutes a promising approach to direct stem cell osteogenic differentiation to promote... 
Advanced Basic Science | Dentistry | Osteogenic differentiation | Hierarchical topography | Cell spread | Mesenchymal stem cells | Titania nanotubes | MATERIALS SCIENCE, BIOMATERIALS | TIO2 NANOTUBES | ENGINEERING, BIOMEDICAL | PROLIFERATION | FATE | ADHESION | IN-VIVO | GROWTH | GENE-EXPRESSION | ALTERED NANOTUBE DIMENSION | LINEAGE | SURFACES | Mesenchymal Stromal Cells - enzymology | Titanium - pharmacology | Bone Marrow Cells - enzymology | Cell Count | Alkaline Phosphatase - metabolism | Titanium - chemistry | Extracellular Matrix - metabolism | Sincalide - metabolism | Nanotubes - chemistry | Cell Differentiation - genetics | Mesenchymal Stromal Cells - cytology | Mesenchymal Stromal Cells - ultrastructure | Bone Marrow Cells - drug effects | Osteogenesis - genetics | Nanotubes - ultrastructure | Mesenchymal Stromal Cells - drug effects | Calcification, Physiologic - drug effects | Bone Marrow Cells - cytology | Extracellular Matrix - drug effects | Osteogenesis - drug effects | Rats | Cell Adhesion - drug effects | Collagen - secretion | Rats, Sprague-Dawley | Bone Marrow Cells - ultrastructure | Cell Shape - drug effects | Gene Expression Regulation - drug effects | Animals | Cell Differentiation - drug effects | Staining and Labeling | Cell Proliferation - drug effects | Cell Cycle - drug effects | Biological products | Phosphatases | Analysis | Collagen | Genes | Stem cells | Fluorescence | Gene expression | Orthodontics | Index Medicus
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 05/2005, Volume 203, Issue 2, pp. 398 - 409
Human mesenchymal stem cells (hMSCs) expanded with and without fibroblast growth factor (FGF) supplementation were compared with respect to their proliferation... 
PROGENITOR CELLS | CROSS-TALK | PROTEIN-KINASE-C | IN-VITRO | PHYSIOLOGY | ATDC5 CELLS | DEFICIENT MDX MICE | STROMAL CELLS | GENE-EXPRESSION SIGNATURES | CHONDROCYTE DIFFERENTIATION | N-CADHERIN | CELL BIOLOGY | Chondrocytes - cytology | Chondrogenesis - drug effects | Age Factors | Oligonucleotide Array Sequence Analysis | Humans | Fibroblast Growth Factor 2 - pharmacology | Bone Marrow Cells - physiology | Gene Expression Profiling | Cell Culture Techniques - methods | Proteoglycans - drug effects | Cell Differentiation - genetics | Chondrocytes - drug effects | Mesenchymal Stromal Cells - cytology | Chondrocytes - physiology | Collagen - drug effects | Up-Regulation - physiology | Bone Marrow Cells - drug effects | Mesenchymal Stromal Cells - physiology | Mesenchymal Stromal Cells - drug effects | Tissue Engineering - methods | Bone Marrow Cells - cytology | Gene Expression Regulation - genetics | Extracellular Matrix Proteins - genetics | Cells, Cultured | Proteoglycans - metabolism | Down-Regulation - drug effects | Extracellular Matrix Proteins - drug effects | Down-Regulation - physiology | Gene Expression Regulation - drug effects | Up-Regulation - drug effects | Chondrogenesis - physiology | Collagen - metabolism | Mitosis - drug effects | Mitosis - physiology | Signal Transduction - drug effects | Cell Differentiation - drug effects | Signal Transduction - physiology | Cell Proliferation - drug effects | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 5, pp. e10431 - e10431
Prostate epithelial cells from both normal and cancer tissues, grown in three-dimensional (3D) culture as spheroids, represent promising in vitro models for... 
EPITHELIAL-MESENCHYMAL TRANSITION | BREAST-CANCER | GENE-EXPRESSION SIGNATURE | STEM-CELLS | MAMMARY EPITHELIA | METASTASIS | BIOLOGY | TUMOR-CELL INVASION | DIFFERENTIATION | CULTURE MODEL | LINES | Laminin - pharmacology | Epithelial Cells - drug effects | Humans | Mesoderm - drug effects | Spheroids, Cellular - pathology | Male | Antineoplastic Agents - therapeutic use | Phosphatidylinositol 3-Kinases - metabolism | Spheroids, Cellular - enzymology | Neoplasm Proteins - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | RNA, Messenger - metabolism | Prostate - pathology | Prostatic Neoplasms - genetics | Cell Transformation, Neoplastic - genetics | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Prostate - drug effects | Antineoplastic Agents - pharmacology | Collagen - pharmacology | Spheroids, Cellular - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Tumor Cells, Cultured | Proto-Oncogene Proteins c-akt - metabolism | Principal Component Analysis | Prostatic Neoplasms - drug therapy | Epithelium - drug effects | Prostatic Neoplasms - pathology | Epithelium - pathology | Neoplasm Invasiveness | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | RNA, Messenger - genetics | Epithelial Cells - pathology | Cell Shape - drug effects | Phenotype | Proteoglycans - pharmacology | Signal Transduction - drug effects | Models, Biological | Prostatic Neoplasms - enzymology | Cell Proliferation - drug effects | TOR Serine-Threonine Kinases | Cell Transformation, Neoplastic - pathology | Mesoderm - pathology | Drug Combinations | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Epigenetic inheritance | Growth | Oncology, Experimental | Genes | Research | Gene expression | Ionizing radiation | Stem cells | Physiological aspects | Models | Drug discovery | Drug therapy | Prostate cancer | Integrins | Cancer | Cell culture | Biotechnology | Transformation | Motility | Leukocyte migration | Mesenchyme | Epithelial cells | Homeostasis | AKT protein | Metastasis | Drug resistance | Tissues | Ovarian cancer | Cell adhesion & migration | Metastases | Rodents | Fibroblasts | Extracellular matrix | Basal lamina | Lipid metabolism | Medical research | Invasiveness | Phenotypic plasticity | Cultures | Tumor cell lines | Metabolism | Spheroids | 1-Phosphatidylinositol 3-kinase | Signaling | Interferon | Three dimensional models | Prostate | Cell migration | Index Medicus
Journal Article
Nature Medicine, ISSN 1078-8956, 07/2015, Volume 21, Issue 7, pp. 786 - 794
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 2014, Volume 211, Issue 13, pp. 2549 - 2566
Journal Article
Cell Stem Cell, ISSN 1934-5909, 01/2017, Volume 20, Issue 1, pp. 56 - 69
Satellite cells, the predominant stem cell population in adult skeletal muscle, are activated in response to hypertrophic stimuli and give rise to myogenic... 
hypertrophy | Pax7 | exosomes | muscle | collagen | microRNA | fibrosis | muscle progenitor cells | extracellular matrix | satellite cells | FIBROSIS | REGENERATION | GENE-EXPRESSION | EXOSOMES | SELF-RENEWAL | DUCHENNE MUSCULAR-DYSTROPHY | MIRNAS | SATELLITE CELL | DIFFERENTIATION | CONNECTIVE-TISSUE | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Exosomes - drug effects | Exosomes - metabolism | NIH 3T3 Cells | Cell Survival - genetics | Extracellular Matrix - metabolism | MicroRNAs - metabolism | PAX7 Transcription Factor - metabolism | Muscle Fibers, Skeletal - drug effects | Muscle Fibers, Skeletal - metabolism | Stem Cells - metabolism | Gene Knockdown Techniques | Cell Differentiation - genetics | Extracellular Matrix - genetics | Cell Nucleus - metabolism | Gene Deletion | Collagen - genetics | Fibroblasts - metabolism | Cell Survival - drug effects | Ribonuclease III - metabolism | Extracellular Matrix - drug effects | Satellite Cells, Skeletal Muscle - metabolism | Down-Regulation - drug effects | Fibroblasts - pathology | Down-Regulation - genetics | Collagen - metabolism | Satellite Cells, Skeletal Muscle - drug effects | Animals | Carrier Proteins - metabolism | Muscle Development - drug effects | Cell Differentiation - drug effects | Models, Biological | Fibroblasts - drug effects | Muscle Fibers, Skeletal - pathology | Tamoxifen - pharmacology | Muscle Development - genetics | Stem Cells - drug effects | Mice | MicroRNAs - genetics | Muscle, Skeletal - pathology | Cell Nucleus - drug effects | Hypertrophy | Index Medicus | miRNA | Dicer | Muscle extracellular matrix
Journal Article
Investigative Ophthalmology & Visual Science, ISSN 0146-0404, 08/2008, Volume 49, Issue 8, pp. 3402 - 3408
Journal Article
Biomaterials, ISSN 0142-9612, 2013, Volume 34, Issue 18, pp. 4404 - 4417
Abstract In bone tissue engineering, a combination of biomimetic nanofibrous scaffolds with renewable stem cells has recently emerged as a new strategy for... 
Advanced Basic Science | Dentistry | Cell proliferation | BMP signaling pathway | Integrin | Nanofibrous hydroxyapatite/chitosan | Cell adhesion | Mesenchymal stem cells | MATRIX | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | NETWORKS | INDUCTION | MESENCHYMAL STEM-CELLS | NANOCOMPOSITES | REPAIR | OSTEOBLASTS | DIFFERENTIATION | PROTEINS | CALVARIAL DEFECTS | Bone Regeneration - genetics | Alkaline Phosphatase - metabolism | Integrins - genetics | Integrins - metabolism | Tissue Scaffolds - chemistry | Extracellular Matrix - genetics | Bone Morphogenetic Proteins - metabolism | Mesenchymal Stromal Cells - cytology | Mesenchymal Stromal Cells - ultrastructure | Skull - pathology | Durapatite - pharmacology | Chitosan - pharmacology | Bone Marrow Cells - drug effects | Female | Bone Morphogenetic Proteins - genetics | Osteogenesis - genetics | Nanofibers - chemistry | Bone Regeneration - drug effects | Mesenchymal Stromal Cells - drug effects | Nanofibers - ultrastructure | Implants, Experimental | Bone Marrow Cells - cytology | Cell Separation | Osteocalcin - metabolism | Extracellular Matrix - drug effects | Osteogenesis - drug effects | Membranes, Artificial | Mesenchymal Stromal Cells - metabolism | Rats | Smad Proteins - genetics | Signal Transduction - genetics | Rats, Sprague-Dawley | Bone Marrow Cells - ultrastructure | Cell Shape - drug effects | Gene Expression Regulation - drug effects | Radiography | Animals | Signal Transduction - drug effects | Skull - diagnostic imaging | Cell Proliferation - drug effects | Smad Proteins - metabolism | Tissue engineering | Collagen | Stem cells | Integrins | Index Medicus
Journal Article
British Journal of Cancer, ISSN 0007-0920, 05/2009, Volume 100, Issue 9, pp. 1425 - 1433
Curcumin has been shown to inhibit the growth of various types of cancer cells; however, at concentrations much above the clinically achievable levels in... 
Curcumin | Chk1 | G2/M arrest | DNA damage | Pancreatic cancer | CARCINOMA-CELLS | DNA-DAMAGE | DOWN-REGULATION | REGULATED GENE-PRODUCTS | FACTOR-KAPPA-B | BENZYL ISOTHIOCYANATE | I CLINICAL-TRIAL | pancreatic cancer | ONCOLOGY | PROSTATE-CANCER | CHEMOPREVENTIVE AGENT | curcumin | Cell Cycle Proteins - drug effects | Protein Kinases - metabolism | Gene Expression Regulation, Enzymologic - drug effects | Protein Kinases - genetics | Gene Silencing - drug effects | Apoptosis - drug effects | Humans | Caspase 3 - metabolism | Collagen Type XI - metabolism | DNA-Binding Proteins - metabolism | Pancreatic Neoplasms - drug therapy | Transfection | Tumor Suppressor Proteins - genetics | Caspase 3 - drug effects | Cell Cycle Proteins - genetics | Gene Expression Regulation, Neoplastic - drug effects | Protein-Serine-Threonine Kinases - metabolism | DNA Damage - drug effects | Protein Kinases - drug effects | Tumor Suppressor Proteins - metabolism | Collagen Type XI - drug effects | Pancreatic Neoplasms - pathology | Cell Cycle Proteins - metabolism | Curcumin - pharmacology | DNA-Binding Proteins - drug effects | Pancreatic Neoplasms - enzymology | Protein-Serine-Threonine Kinases - genetics | Ataxia Telangiectasia Mutated Proteins | DNA-Binding Proteins - genetics | Cell Division - drug effects | Protein-Serine-Threonine Kinases - drug effects | Cell Line, Tumor | Checkpoint Kinase 1 | Tumor Suppressor Proteins - drug effects | Cell Cycle - drug effects | Index Medicus | Translational Therapeutics | M arrest
Journal Article
Biomaterials, ISSN 0142-9612, 2015, Volume 51, pp. 173 - 183
Abstract Polyetheretherketone (PEEK) possesses a similar elastic modulus as bones but yet suffers from bio-inertness and poor osteogenesis. In this work,... 
Advanced Basic Science | Dentistry | Polyetheretherketone | Elastic modulus | Tantalum | Osteointegration | Plasma immersion ion implantation | STEM-CELLS | MATERIALS SCIENCE, BIOMATERIALS | ETHER-ETHER-KETONE | HUMAN OSTEOBLASTS | ENGINEERING, BIOMEDICAL | BIOACTIVE MATERIALS | MECHANICAL-PROPERTIES | METALLIC BIOMATERIALS | IN-VITRO | POROUS TANTALUM | IMMERSION ION-IMPLANTATION | NANOCOMPOSITE COATINGS | Mesenchymal Stromal Cells - enzymology | Bone Marrow Cells - enzymology | Alkaline Phosphatase - metabolism | Extracellular Matrix - metabolism | Fluorescent Dyes - metabolism | Elastic Modulus - drug effects | X-Ray Microtomography | Bone and Bones - drug effects | Mesenchymal Stromal Cells - cytology | Bone and Bones - diagnostic imaging | Surface Properties | Tantalum - pharmacology | Bone Marrow Cells - drug effects | Real-Time Polymerase Chain Reaction | Osteogenesis - genetics | Osseointegration - drug effects | Polyethylene Glycols - pharmacology | Ketones - pharmacology | Mesenchymal Stromal Cells - drug effects | Photoelectron Spectroscopy | Bone and Bones - physiology | Calcification, Physiologic - drug effects | Bone Marrow Cells - cytology | Extracellular Matrix - drug effects | Osteogenesis - drug effects | Cells, Cultured | Prostheses and Implants | Rats | Cell Adhesion - drug effects | Collagen - secretion | Gene Expression Regulation - drug effects | Animals | Cell Proliferation - drug effects | Collagen | Analysis | Stem cells | Medical colleges | Phosphatases | Ceramics | Implant dentures | Ceramic materials | Index Medicus | Biomedical materials | Dental materials | Biocompatibility | Bones | Modulus of elasticity | Polyetheretherketones
Journal Article