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PLoS ONE, ISSN 1932-6203, 07/2017, Volume 12, Issue 7, pp. e0181535 - e0181535
Journal Article
Physiological Reports, 06/2019, Volume 7, Issue 11, pp. e14106 - n/a
Bone fractures are associated with considerable morbidity and increased mortality. A major limitation to healing is lack of bone blood flow, which is impaired... 
Angiogenesis | calvaria | blood flow | bone scaffold | bone fracture | femur | Osteoprogenitor cells | Femur | Animal models | Bone healing | Bone (trabecular) | Males | Relaxin | Morbidity | Vasodilation | Blood flow | Bone blood flow | Hemopoiesis | Pregnancy | Studies | Bone growth | Fractures | Collagen | Bone marrow | Skull | Females | Osteogenesis
Journal Article
European Urology, ISSN 0302-2838, 2017, Volume 72, Issue 1, pp. 142 - 150
Journal Article
Molecular Immunology, ISSN 0161-5890, 06/2012, Volume 51, Issue 2, pp. 101 - 111
► We describe a high, synergistic induction of IDO1 expression by the demethylating drug zebularine and IFN-γ in the human monocytic cell line THP-1. ► The... 
DNA methylation | IFN-γ | Transcription factors | Zebularine | IDO1 gene promoter | Human and rat | COLLAGEN-INDUCED ARTHRITIS | DENDRITIC CELLS | PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | DNA METHYLTRANSFERASE INHIBITORS | IMMUNOLOGY | TRYPTOPHAN CATABOLISM | T-CELL PROLIFERATION | IFN-gamma | IMMUNE SUPPRESSION | HUMAN GLIOBLASTOMA | GENE-EXPRESSION | INTERFERON REGULATORY FACTOR-1 | Indoleamine-Pyrrole 2,3,-Dioxygenase - biosynthesis | Indoleamine-Pyrrole 2,3,-Dioxygenase - genetics | Promoter Regions, Genetic | Cytidine - administration & dosage | Gene Expression - drug effects | Humans | Cells, Cultured | Rats | Cytidine - analogs & derivatives | Reverse Transcriptase Polymerase Chain Reaction | STAT1 Transcription Factor - genetics | Interferon Regulatory Factor-1 - genetics | Autoimmune Diseases - genetics | Drug Synergism | Gene Expression Regulation - drug effects | DNA Methylation | Animals | Epigenesis, Genetic - genetics | Interferon-gamma - administration & dosage | Real-Time Polymerase Chain Reaction | STAT1 Transcription Factor - biosynthesis | Interferon Regulatory Factor-1 - biosynthesis | Index Medicus | Inflammation | Interferon regulatory factor 1 | Tryptophan 2,3-dioxygenase | Promoters | epigenetics | Demethylation | Immunosuppression | Monocytes | Colon cancer | gamma -Interferon | DNA methyltransferase | Autoimmune diseases | Stat1 protein | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Immunologi inom det medicinska området | Immunology in the medical area
Journal Article
by Hsu, YC and Chen, MJ and Yu, YM and Ko, SY and Chang, CC
ARCHIVES OF DERMATOLOGICAL RESEARCH, ISSN 0340-3696, 12/2010, Volume 302, Issue 10, pp. 717 - 724
Keloid is a fibrotic disease characterized by abnormal accumulation of extracellular matrix (ECM) in the dermis. It is a late spreading skin overgrowth and may... 
Transforming growth factor-beta 1 (TGF-beta 1) | CELLS | APOPTOSIS | EXOGENOUS NITRIC-OXIDE | Keloid | Curcuminoids | PROLIFERATION | HYPERTROPHIC SCARS | DERMATOLOGY | GROWTH-FACTOR-BETA | INHIBITION | COLLAGEN-SYNTHESIS | HUMAN SKIN FIBROBLASTS | Extracellular matrix (ECM) | EXPRESSION
Journal Article
Science, ISSN 0036-8075, 4/2011, Volume 332, Issue 6028, pp. 478 - 484
The growth factor progranulin (PGRN) has been implicated in embryonic development, tissue repair, tumorigenesis, and inflammation, but its receptors remain... 
Cartilage | Immunization | Antiinflammatories | Medical treatment | REPORTS | Collagens | Antibodies | Bones | Arthritis | Mice | Inflammation | TUMOR-NECROSIS-FACTOR | GENE | MULTIDISCIPLINARY SCIENCES | HOST-DEFENSE | DEGRADATION | OLIGOMERIC MATRIX PROTEIN | GRANULIN-EPITHELIN PRECURSOR | ADAMTS-7 | MUTATIONS | TRANSCRIPTION FACTOR | PSEUDOACHONDROPLASIA | Recombinant Proteins - therapeutic use | Tumor Necrosis Factor-alpha - metabolism | Arthritis, Experimental - drug therapy | Recombinant Fusion Proteins - pharmacology | Humans | Middle Aged | Recombinant Fusion Proteins - therapeutic use | Intercellular Signaling Peptides and Proteins - chemistry | Male | Receptors, Tumor Necrosis Factor, Type I - metabolism | Recombinant Fusion Proteins - metabolism | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | T-Lymphocytes, Regulatory - immunology | Arthritis, Experimental - pathology | Young Adult | Intercellular Signaling Peptides and Proteins - metabolism | Cartilage, Articular - metabolism | Receptors, Tumor Necrosis Factor, Type II - metabolism | Adult | Female | Protein Interaction Domains and Motifs | Anti-Inflammatory Agents, Non-Steroidal - metabolism | T-Lymphocytes, Regulatory - physiology | Arthritis, Experimental - physiopathology | Signal Transduction | Intercellular Signaling Peptides and Proteins - genetics | Mice, Transgenic | Arthritis, Experimental - immunology | Mice, Inbred Strains | Receptors, Tumor Necrosis Factor, Type I - genetics | Receptors, Tumor Necrosis Factor, Type II - genetics | Mice, Knockout | Cartilage, Articular - pathology | Animals | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Adolescent | Ligands | Aged | Intercellular Signaling Peptides and Proteins - therapeutic use | Care and treatment | Genetic aspects | Properties | Tumor necrosis factor | Growth factors | Index Medicus | Binding | Pathology | Receptors | Pathogenesis
Journal Article
Cancer discovery, ISSN 2159-8274, 06/2011, Volume 1, Issue 1, pp. 78 - 89
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 01/2017, Volume 245, pp. 81 - 94
Development of an effective treatment against advanced tumors remains a major challenge for cancer immunotherapy. We have previously developed a potent... 
Peptide vaccine | Tumor microenvironment | Sunitinib base | Advanced melanoma | Polymeric micelles | CANCER-IMMUNOTHERAPY | COMBINATION | CHEMISTRY, MULTIDISCIPLINARY | CHEMOTHERAPY | BREAST-CANCER | NANOPARTICLES | CO-DELIVERY | CISPLATIN | IMMUNE SUPPRESSION | GROWTH | CELL CARCINOMA PATIENTS | PHARMACOLOGY & PHARMACY | Polymers - administration & dosage | Oligodeoxyribonucleotides - administration & dosage | Calcium Phosphates - therapeutic use | Oligodeoxyribonucleotides - chemistry | Immunotherapy, Active | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Membrane Proteins - therapeutic use | Indoles - administration & dosage | Polymers - therapeutic use | Cancer Vaccines - therapeutic use | Pyrroles - administration & dosage | Micelles | Female | Proto-Oncogene Proteins c-akt - metabolism | Pyrroles - therapeutic use | STAT3 Transcription Factor - metabolism | Cytokines - immunology | Oligodeoxyribonucleotides - therapeutic use | Melanoma - metabolism | Tumor Microenvironment - drug effects | Cell Survival - drug effects | Cancer Vaccines - administration & dosage | Mice, Inbred C57BL | Peptide Fragments - administration & dosage | Calcium Phosphates - chemistry | Melanoma - pathology | Antineoplastic Agents - chemistry | Membrane Proteins - administration & dosage | Peptide Fragments - chemistry | Animals | Membrane Proteins - chemistry | Tumor Burden - drug effects | Melanoma - immunology | Calcium Phosphates - administration & dosage | Cell Line, Tumor | Pyrroles - chemistry | Indoles - therapeutic use | Polymers - chemistry | Peptide Fragments - therapeutic use | Melanoma - therapy | Indoles - chemistry | Tyrosine | Care and treatment | Analysis | Immunotherapy | Melanoma | Calcium phosphate | Vaccines | T cells | Tumors | Cancer | Index Medicus | Advanced Melanoma
Journal Article
International Journal of Molecular Medicine, ISSN 1107-3756, 5/2013, Volume 31, Issue 5, pp. 1148 - 1152
The inhibition of the Smad2/3 pathway is a key step involved in the downregulation of type I collagen synthesis, thus preventing keloid formation in tissue. In... 
type I collagen | fibroblasts | Smad | silibinin | Fibroblasts | Type I collagen | Silibinin | FIBROSIS | MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | TGF-BETA | STIMULATION | PROTEIN | MECHANISMS | GROWTH-FACTOR-BETA | GENE-EXPRESSION | SILYMARIN | Proteins | Immunoglobulins | Phosphorylation | Scars | Collagen | Extracellular matrix | Cytotoxicity | Kinases | Growth factors
Journal Article
Journal of Endodontics, ISSN 0099-2399, 2013, Volume 39, Issue 7, pp. 929 - 934
Journal Article
Journal of Periodontology, ISSN 0022-3492, 08/2013, Volume 84, Issue 8, pp. 1180 - 1190
Background: Alveolar bone loss can be a major clinical concern affecting both functionality and esthetics. Osteoblasts are the main cells charged with the... 
intercellular signaling peptides and proteins | osteoblasts | Blood platelets | platelet‐rich plasma | regeneration | bone and bones | Regeneration | Intercellular signaling peptides and proteins | Bone and bones | Osteoblasts | Platelet-rich plasma | STEM-CELLS | DENTAL IMPLANTS | CHEMOTACTIC MIGRATION | MECHANISMS | MEDICINE | platelet-rich plasma | RESPONSES | IN-VITRO | PLATELETS | DENTISTRY, ORAL SURGERY & MEDICINE | MORPHOGENETIC PROTEIN-2 | FIBRIN MATRICES | Hepatocyte Growth Factor - therapeutic use | Intercellular Signaling Peptides and Proteins - analysis | Plasma | Platelet-Derived Growth Factor - therapeutic use | Proto-Oncogene Proteins c-sis - analysis | Humans | Middle Aged | Alveolar Process - drug effects | Male | Autocrine Communication - drug effects | Endothelial Growth Factors - analysis | Alveolar Process - cytology | Osteocalcin - therapeutic use | Platelet-Derived Growth Factor - analysis | Aged, 80 and over | Alkaline Phosphatase - analysis | Adult | Female | Cell Culture Techniques | Endothelial Growth Factors - therapeutic use | Transforming Growth Factor beta1 - analysis | Insulin-Like Growth Factor I - therapeutic use | Osteocalcin - analysis | Bone Regeneration - drug effects | Hepatocyte Growth Factor - analysis | Osteoblasts - drug effects | Vascular Endothelial Growth Factor A - therapeutic use | Cells, Cultured | Vascular Endothelial Growth Factor A - analysis | Chemotaxis - drug effects | Insulin-Like Growth Factor I - analysis | Cell Movement - drug effects | Transforming Growth Factor beta1 - therapeutic use | Proto-Oncogene Proteins c-sis - therapeutic use | Platelet-Rich Plasma | Aged | Cell Proliferation - drug effects | Collagen Type I - analysis | Intercellular Signaling Peptides and Proteins - therapeutic use | Collagen Type I - therapeutic use | Index Medicus | Dentistry
Journal Article