X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (16861) 16861
Magazine Article (43) 43
Book / eBook (16) 16
Book Chapter (10) 10
Dissertation (8) 8
Conference Proceeding (4) 4
Publication (4) 4
Web Resource (2) 2
Book Review (1) 1
Newsletter (1) 1
Streaming Video (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (14820) 14820
colonic neoplasms - drug therapy (9969) 9969
colonic neoplasms - pathology (6885) 6885
female (6384) 6384
male (6213) 6213
animals (5854) 5854
oncology (5647) 5647
mice (4364) 4364
colon cancer (4119) 4119
middle aged (3878) 3878
cancer (3672) 3672
aged (3484) 3484
colonic neoplasms - metabolism (3356) 3356
cell line, tumor (3270) 3270
colorectal cancer (2617) 2617
apoptosis (2484) 2484
adult (2438) 2438
colorectal-cancer (2179) 2179
colonic neoplasms - genetics (2117) 2117
apoptosis - drug effects (1971) 1971
antineoplastic combined chemotherapy protocols - therapeutic use (1889) 1889
adenocarcinoma - drug therapy (1846) 1846
chemotherapy (1776) 1776
antineoplastic agents - pharmacology (1775) 1775
expression (1675) 1675
tumor cells, cultured (1638) 1638
colonic neoplasms - surgery (1609) 1609
fluorouracil - administration & dosage (1583) 1583
antineoplastic agents - therapeutic use (1570) 1570
mice, nude (1531) 1531
mice, inbred balb c (1468) 1468
tumors (1418) 1418
cell proliferation - drug effects (1412) 1412
pharmacology & pharmacy (1342) 1342
colon (1295) 1295
surgery (1275) 1275
rectal neoplasms - drug therapy (1261) 1261
biochemistry & molecular biology (1212) 1212
colonic neoplasms - therapy (1207) 1207
fluorouracil - therapeutic use (1190) 1190
research (1152) 1152
liver neoplasms - secondary (1090) 1090
treatment outcome (1085) 1085
care and treatment (1061) 1061
therapy (1049) 1049
neoplasm staging (1046) 1046
analysis (1043) 1043
dose-response relationship, drug (1030) 1030
gastroenterology & hepatology (1015) 1015
ht29 cells (999) 999
aged, 80 and over (993) 993
adenocarcinoma - pathology (984) 984
chemotherapy, adjuvant (984) 984
metastasis (979) 979
prognosis (973) 973
carcinoma (960) 960
neoplasm transplantation (960) 960
fluorouracil (950) 950
rats (948) 948
cell biology (938) 938
cell survival - drug effects (933) 933
xenograft model antitumor assays (903) 903
colonic neoplasms - mortality (892) 892
time factors (889) 889
hct116 cells (888) 888
liver neoplasms - drug therapy (884) 884
health aspects (881) 881
growth (880) 880
cells (836) 836
combined modality therapy (792) 792
antineoplastic agents - administration & dosage (783) 783
proteins (782) 782
activation (779) 779
medicine & public health (775) 775
5-fluorouracil (759) 759
colonic neoplasms - enzymology (758) 758
colonic neoplasms - immunology (739) 739
inhibition (722) 722
survival (710) 710
cell division - drug effects (688) 688
breast neoplasms - drug therapy (682) 682
research article (671) 671
risk factors (668) 668
in-vitro (653) 653
neoplasm metastasis (643) 643
gene expression (637) 637
drug synergism (635) 635
cell proliferation (621) 621
drug administration schedule (621) 621
medicine, research & experimental (615) 615
leucovorin - administration & dosage (601) 601
lung neoplasms - drug therapy (601) 601
blotting, western (596) 596
colonic neoplasms (593) 593
gene expression regulation, neoplastic (590) 590
disease models, animal (583) 583
colonic neoplasms - prevention & control (581) 581
fluorouracil - adverse effects (579) 579
signal transduction (573) 573
cytotoxicity (566) 566
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (15815) 15815
Japanese (780) 780
German (238) 238
French (205) 205
Chinese (117) 117
Russian (67) 67
Spanish (57) 57
Italian (56) 56
Polish (18) 18
Portuguese (16) 16
Korean (15) 15
Hungarian (14) 14
Danish (13) 13
Dutch (11) 11
Norwegian (9) 9
Swedish (7) 7
Romanian (6) 6
Ukrainian (6) 6
Hebrew (5) 5
Croatian (3) 3
Finnish (2) 2
Serbian (2) 2
Afrikaans (1) 1
Bulgarian (1) 1
Czech (1) 1
Slovak (1) 1
Turkish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature medicine, ISSN 1546-170X, 2017, Volume 23, Issue 6, pp. 664 - 673
Neuroendocrine (NE) cancers are a diverse group of neoplasms typically diagnosed and treated on the basis of their site of origin... 
MOLECULAR CHARACTERIZATION | MEDICINE, RESEARCH & EXPERIMENTAL | PANCREATIC ENDOCRINE NEOPLASMS | BIOCHEMISTRY & MOLECULAR BIOLOGY | GASTROINTESTINAL-TRACT | AUTOCHTHONOUS PROSTATE-CANCER | T-ANTIGEN | CELL BIOLOGY | CELL LUNG-CANCER | TRANSGENIC ADENOCARCINOMA | MOUSE MODEL | N-MYC | MUTATIONAL LANDSCAPE | Lung Neoplasms - drug therapy | Colonic Neoplasms - genetics | Carcinoma, Small Cell - genetics | Colonic Neoplasms - drug therapy | Epigenesis, Genetic | Humans | Male | Antineoplastic Agents - therapeutic use | Molecular Targeted Therapy | Tumor Suppressor Protein p53 - genetics | Ovarian Neoplasms - genetics | Neoplasms, Glandular and Epithelial - genetics | Prostatic Neoplasms - genetics | Urinary Bladder Neoplasms - genetics | Female | Cell Differentiation | Retinoblastoma Binding Proteins - genetics | Ovarian Neoplasms - drug therapy | Prostatic Neoplasms - drug therapy | Triazoles - therapeutic use | Lung Neoplasms - genetics | Antibodies, Monoclonal, Humanized - therapeutic use | Carcinoma, Neuroendocrine - drug therapy | Carcinoma, Small Cell - drug therapy | Carcinogenesis - genetics | Head and Neck Neoplasms - drug therapy | Carcinoma, Neuroendocrine - genetics | Uterine Cervical Neoplasms - drug therapy | Urinary Bladder Neoplasms - drug therapy | Uterine Cervical Neoplasms - genetics | Disease Progression | Azepines - therapeutic use | Neuroendocrine Tumors - genetics | Proto-Oncogene Proteins c-met - genetics | Cell Lineage | Cell Plasticity - genetics | Esophageal Neoplasms - genetics | Pyrimidines - therapeutic use | Neuroendocrine Tumors - drug therapy | Head and Neck Neoplasms - genetics | Proto-Oncogene Proteins c-myc - genetics | Ubiquitin-Protein Ligases - genetics | Benzodiazepines - therapeutic use | Esophageal Neoplasms - drug therapy | Proteins | Research | Health aspects | Carcinogenesis | Gastrin
Journal Article
Cancer, ISSN 0008-543X, 03/2016, Volume 122, Issue 5, pp. 782 - 790
Journal Article
Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 2010, Volume 138, Issue 6, pp. 2101 - 2114.e5
The connection between inflammation and tumorigenesis is well-established and in the last decade has received a great deal of supporting evidence from genetic,... 
Gastroenterology and Hepatology | Inflammation | Cytokines | Immunity | Colon Cancer | CHRONIC INTESTINAL INFLAMMATION | COLITIS-ASSOCIATED CANCER | SEVERE CROHNS-DISEASE | EPITHELIAL-MESENCHYMAL TRANSITION | TUMOR-NECROSIS-FACTOR | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | KINASE-I-EPSILON | TOLL-LIKE RECEPTORS | GASTROENTEROLOGY & HEPATOLOGY | NF-KAPPA-B | GENOME-WIDE ASSOCIATION | Colonic Neoplasms - genetics | Colonic Neoplasms - prevention & control | Colonic Neoplasms - drug therapy | Colorectal Neoplasms - genetics | Humans | Inflammatory Bowel Diseases - immunology | Gene Expression Regulation, Neoplastic | Colon - immunology | Cell Transformation, Neoplastic - genetics | Colonic Neoplasms - immunology | Colorectal Neoplasms - drug therapy | Inflammation Mediators - metabolism | Inflammatory Bowel Diseases - genetics | Anti-Inflammatory Agents - therapeutic use | Inflammatory Bowel Diseases - complications | Anticarcinogenic Agents - therapeutic use | Inflammatory Bowel Diseases - drug therapy | Genetic Predisposition to Disease | Cytokines - metabolism | Risk Assessment | Signal Transduction | Neoplasm Invasiveness | Risk Factors | Colorectal Neoplasms - prevention & control | Colonic Neoplasms - secondary | Cell Transformation, Neoplastic - immunology | Animals | Colorectal Neoplasms - immunology | Colorectal Neoplasms - secondary | Colon - microbiology | Dendritic cells | Measles-mumps-rubella vaccine | Biological response modifiers | Sulfates | Risk factors | Dextran | Prostaglandins | Colon cancer | Gastrointestinal diseases | Vascular endothelial growth factor | Growth factors | Tumors
Journal Article
Amino Acids, ISSN 0939-4451, 10/2011, Volume 41, Issue 4, pp. 893 - 899
S100P expression is described in many different cancers, and its expression is associated with drug resistance, metastasis, and poor clinical outcome... 
Life Sciences | Biochemistry, general | Analytical Chemistry | Life Sciences, general | Calcium-binding protein | Neurobiology | Biochemical Engineering | Proteomics | S100P | RAGE | Cromolyn | Cancer | ANTIALLERGIC DRUGS | BIOCHEMISTRY & MOLECULAR BIOLOGY | PANCREATIC-CANCER | DIFFERENTIAL GENE-EXPRESSION | MICROARRAY ANALYSIS | CELL LUNG-CANCER | BREAST-CANCER | BINDING PROTEIN S100P | DYSREGULATED EXPRESSION | NF-KAPPA-B | CA2+-BINDING PROTEIN | Calcium-Binding Proteins - metabolism | Neoplasms - metabolism | Lung Neoplasms - drug therapy | Prostatic Neoplasms - metabolism | Pancreatic Neoplasms - metabolism | Colonic Neoplasms - drug therapy | Humans | Lung Neoplasms - metabolism | Receptor for Advanced Glycation End Products - metabolism | Gene Expression Regulation, Neoplastic | Male | Neoplasm Proteins - metabolism | Breast Neoplasms - drug therapy | Colonic Neoplasms - metabolism | Breast Neoplasms - metabolism | Neoplasms - drug therapy | Pancreatic Neoplasms - drug therapy | Drug Design | Female | Neoplasm Proteins - genetics | Neoplasms - pathology | Prostatic Neoplasms - drug therapy | Calcium-Binding Proteins - genetics | Care and treatment | Peptides | Oncology, Experimental | Research | Metastasis | Binding proteins | Drug resistance | Health aspects | Calmodulin | Drugs | Receptors | Genes | Markers | Blocking | Amino acids | Gene expression
Journal Article
Nature (London), ISSN 1476-4687, 2016, Volume 534, Issue 7609, pp. 647 - 651
... their efficacy as single agents. Here we take a systematic approach towards identifying combination targets for trametinib, a MEK inhibitor approved by the US Food and Drug Administration, which acts downstream of KRAS to suppress... 
COLON-CANCER | SELECTIVE INHIBITOR | POTENT | FEEDBACK ACTIVATION | MEK INHIBITION | RAS | MULTIDISCIPLINARY SCIENCES | ACQUIRED-RESISTANCE | BRAF | MEDIATED REACTIVATION | DISCOVERY | Lung Neoplasms - drug therapy | Colonic Neoplasms - genetics | Adenocarcinoma - pathology | Adenocarcinoma of Lung | Proto-Oncogene Proteins p21(ras) - genetics | Humans | Receptor, Fibroblast Growth Factor, Type 1 - metabolism | Drug Resistance, Neoplasm | Lung Neoplasms - pathology | Pyridazines - pharmacology | Female | Pyrimidinones - pharmacology | Adenocarcinoma - genetics | Cell Death - drug effects | Imidazoles - therapeutic use | Phosphorylation - drug effects | Pyridazines - therapeutic use | Disease Models, Animal | Lung Neoplasms - genetics | Pancreatic Neoplasms - pathology | Pyrimidinones - therapeutic use | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Mutant Proteins - genetics | Antineoplastic Combined Chemotherapy Protocols | Pancreatic Neoplasms - genetics | Imidazoles - pharmacology | Enzyme Activation - drug effects | Adenocarcinoma - drug therapy | Receptor, Fibroblast Growth Factor, Type 1 - antagonists & inhibitors | Xenograft Model Antitumor Assays | Feedback, Physiological | Animals | MAP Kinase Signaling System - drug effects | Colonic Neoplasms - pathology | Cell Proliferation - drug effects | Mice | Pyridones - therapeutic use | Mutation | Pyridones - pharmacology | Drug Screening Assays, Antitumor | Molecular targeted therapy | Care and treatment | Cell death | Lung cancer | Methods | Cancer cells | Phosphorylation | Chemotherapy | Inhibitor drugs | Drug resistance | Tumors
Journal Article
Nature (London), ISSN 1476-4687, 2018, Volume 554, Issue 7693, pp. 538 - 543
Most patients with colorectal cancer die as a result of the disease spreading to other organs. However, no prevalent mutations have been associated with... 
STEM-CELLS | DISRUPTION | GENE | COLORECTAL-CANCER | MULTIDISCIPLINARY SCIENCES | LEADS | MICE | GROWTH-FACTOR | EXPRESSION | PROGRESSION | TRANSPLANTATION | Intestines - drug effects | Colonic Neoplasms - genetics | Intestinal Mucosa - metabolism | Colonic Neoplasms - drug therapy | Humans | Male | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Stem Cells - metabolism | Th1 Cells - immunology | T-Lymphocytes, Cytotoxic - drug effects | Neoplasm Metastasis - drug therapy | Neoplasm Metastasis - immunology | Colonic Neoplasms - immunology | Immunotherapy | Transforming Growth Factor beta - antagonists & inhibitors | Female | Liver Neoplasms - secondary | Disease Models, Animal | T-Lymphocytes, Cytotoxic - immunology | Transforming Growth Factor beta - immunology | Tumor Microenvironment - drug effects | Th1 Cells - drug effects | Intestines - pathology | Liver Neoplasms - drug therapy | Liver Neoplasms - immunology | Drug Synergism | Tumor Microenvironment - immunology | Neoplasm Metastasis - genetics | Animals | Cell Differentiation - drug effects | Neoplasm Metastasis - pathology | Colonic Neoplasms - pathology | Alleles | Immune Evasion - drug effects | Stem Cells - drug effects | Stem Cells - pathology | Mice | Mutation | T-Lymphocytes, Cytotoxic - cytology | PD-1 protein | Liver | Colorectal carcinoma | Colorectal cancer | Stem cell transplantation | Cytotoxicity | Lymphocytes T | Metastasis | Metastases | Colon cancer | Intestine | Lymphocytes | Genetic analysis | Fibroblasts | Colon | Inhibition | Growth factors | Phenotypes | Data analysis | Liver diseases | Microsatellites | Organs | Gene expression | Patients | Signaling | Immune checkpoint | PD-L1 protein | Stem cells | Tumors | Cancer
Journal Article
Journal Article
European Radiology, ISSN 0938-7994, 7/2015, Volume 25, Issue 7, pp. 2033 - 2040
Journal Article
PloS one, ISSN 1932-6203, 2017, Volume 12, Issue 6, p. e0179501
Innovative therapies for solid tumors are urgently needed. Recently, therapies that harness the host immune system to fight cancer cells have successfully treated a subset of patients with solid tumors... 
CD2 | THERAPY | IMMUNOTHERAPY | MULTIDISCIPLINARY SCIENCES | GENES | IMMUNOMODULATORY ACTION | MECHANISMS | MOLECULES | SGI-110 | Colonic Neoplasms - genetics | DNA Methylation - immunology | DNA, Neoplasm - metabolism | Humans | Antigens, Neoplasm - biosynthesis | Ovarian Neoplasms - pathology | Male | Colonic Neoplasms - metabolism | Testicular Neoplasms - pathology | Ovarian Neoplasms - genetics | Colonic Neoplasms - immunology | Female | Ovarian Neoplasms - metabolism | Caco-2 Cells | Antigens, Neoplasm - genetics | Testicular Neoplasms - genetics | Antigens, Neoplasm - immunology | Testicular Neoplasms - metabolism | Antigen Presentation - genetics | DNA Methylation - genetics | Testicular Neoplasms - immunology | Animals | Colonic Neoplasms - pathology | DNA, Neoplasm - immunology | Mice | DNA, Neoplasm - genetics | Ovarian Neoplasms - immunology | Colon cancer | Tumor antigens | Physiological aspects | Development and progression | Genetic aspects | Research | Methylation | Ovarian cancer | Therapy | Biotechnology | Animal models | Ovarian carcinoma | Medical innovations | CD58 antigen | Antigen processing | Genomes | Tissues | Cancer therapies | Immunotherapy | Surgery | Cell cycle | DNA methylation | Inhibition | Colon | Drug dosages | Deoxyribonucleic acid--DNA | Immune system | Antigen presentation | Antigens | Tumor cells | Melanoma | Tumor cell lines | Gene expression | Ribonucleic acid--RNA | Patients | Medicine | Inhibitors | Epigenetics | Solid tumors | Tumors | Cancer | RNA | Deoxyribonucleic acid | Ribonucleic acid | DNA
Journal Article