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1. Full Text Immunohistochemical localization of hTERT protein in human tissues
by Yan, Pu and Benhattar, Jean and Seelentag, Walter and Stehle, Jean-Christophe and Bosman, Fred T
Histochemistry and cell biology, ISSN 0948-6143, 5/2004, Volume 121, Issue 5, pp. 391 - 397
Immunohistochemistry | RT-PCR | Apoptotic cells | hTERT | LifeSciences | Telomerase | TRAP assay | RT-PCR apoptotic cells | Colonic Neoplasms - genetics | Gene Expression - genetics | Humans | Urinary Bladder Neoplasms - enzymology | Cytoplasm - metabolism | Lung Neoplasms - pathology | Male | Sarcoma - enzymology | RNA, Neoplasm - isolation & purification | Telomerase - immunology | Spermatogonia - metabolism | Cell Nucleus - enzymology | Breast Neoplasms - enzymology | Keratins - analysis | Telomerase - genetics | Urinary Bladder Neoplasms - genetics | Neoplasms - genetics | Cell Nucleolus - metabolism | Urinary Bladder Neoplasms - pathology | Female | Telomerase - metabolism | Adenocarcinoma - genetics | Sarcoma - genetics | Antibodies, Monoclonal - immunology | DNA-Binding Proteins | Lung Neoplasms - genetics | Lymphocytes - metabolism | Cytoplasm - enzymology | Lung Neoplasms - enzymology | Keratins - immunology | Adenocarcinoma - enzymology | Neoplasms - enzymology | Reverse Transcriptase Polymerase Chain Reaction | Sarcoma - pathology | Immunohistochemistry - methods | Breast Neoplasms - genetics | Cell Nucleus - genetics | Breast Neoplasms - pathology | Lymphocytes - enzymology | RNA, Neoplasm - genetics | Cell Nucleolus - enzymology | Colonic Neoplasms - enzymology | Spermatogonia - enzymology | Neoplasms - pathology | Apoptosis | Index Medicus
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2. Full Text Understanding the role of primary tumour localisation in colorectal cancer treatment and outcomes
by Stintzing, Sebastian and Tejpar, Sabine and Gibbs, Peter and Thiebach, Lars and Lenz, Heinz-Josef
European journal of cancer (1990), ISSN 0959-8049, 10/2017, Volume 84, pp. 69 - 80
Hindgut | Midgut | Colorectal carcinoma | Predictive | Metastatic | Colon | Prognostic | Life Sciences & Biomedicine | Oncology | Science & Technology | Predictive Value of Tests | Receptor, Epidermal Growth Factor - genetics | Colonic Neoplasms - genetics | Colonic Neoplasms - drug therapy | Colorectal Neoplasms - genetics | Humans | Antineoplastic Agents - therapeutic use | Molecular Diagnostic Techniques | Neoplasm Metastasis | Receptor, Epidermal Growth Factor - metabolism | Rectal Neoplasms - genetics | Colorectal Neoplasms - drug therapy | Biomarkers, Tumor - metabolism | Rectal Neoplasms - pathology | Biomarkers, Tumor - antagonists & inhibitors | Rectal Neoplasms - drug therapy | Precision Medicine | Colorectal Neoplasms - enzymology | Gastrointestinal Microbiome | Treatment Outcome | Rectal Neoplasms - enzymology | Protein Kinase Inhibitors - therapeutic use | Colonic Neoplasms - pathology | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Biomarkers, Tumor - genetics | Colonic Neoplasms - enzymology | Mutation | Colorectal Neoplasms - pathology | Medical research | Care and treatment | Colorectal cancer | Medicine, Experimental | Drug therapy | Tumors | Cancer | Epidermal growth factor | Metastasis | Spleen | Impact prediction | Microbiomes | Patients | Flexing | Molecular chains | Metastases | Rectum | Index Medicus
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3. Full Text MnSOD upregulation sustains the Warburg effect via mitochondrial ROS and AMPK-dependent signalling in cancer
by Hart, Peter C and Mao, Mao and De Abreu, Andre Luelsdorf P and Ansenberger-Fricano, Kristine and Ekoue, Dede N and Ganini, Douglas and Kajdacsy-Balla, Andre and Diamond, Alan M and Minshall, Richard D and Consolaro, Marcia E. L and Santos, Janine H and Bonini, Marcelo G
Nature communications, ISSN 2041-1723, 2015, Volume 6, Issue 1, pp. 6053 - 6053
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Mitochondria - enzymology | RNA, Small Interfering - genetics | AMP-Activated Protein Kinases - metabolism | Colonic Neoplasms - genetics | Superoxide Dismutase - genetics | Reactive Oxygen Species - metabolism | Humans | Transcriptional Activation | Gene Expression Regulation, Neoplastic | Phosphofructokinase-1 - genetics | Superoxide Dismutase - antagonists & inhibitors | Male | Glycolysis - genetics | Breast Neoplasms - enzymology | Prostatic Neoplasms - genetics | Mitochondria - genetics | Female | Hexokinase - genetics | Superoxide Dismutase - metabolism | Prostatic Neoplasms - pathology | Oxidation-Reduction | Pyruvate Kinase - metabolism | Signal Transduction | AMP-Activated Protein Kinases - antagonists & inhibitors | Hydrogen Peroxide - metabolism | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Colonic Neoplasms - pathology | Cell Line, Tumor | Prostatic Neoplasms - enzymology | Colonic Neoplasms - enzymology | Hexokinase - metabolism | Neoplasm Staging | Phosphofructokinase-1 - metabolism | Pyruvate Kinase - genetics | AMP-Activated Protein Kinases - genetics | RNA, Small Interfering - metabolism | Index Medicus
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4. Full Text Endocrine-related cancers and the role of AMPK
by Brown, Kristy A and Samarajeewa, Nirukshi U and Simpson, Evan R
Molecular and cellular endocrinology, ISSN 0303-7207, 02/2013, Volume 366, Issue 2, pp. 170 - 179
AMPK | Breast cancer | Colon cancer | Endometrial cancer | Prostate cancer | Ovarian cancer | Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Cell Biology | AMP-Activated Protein Kinases - metabolism | Colonic Neoplasms - genetics | Metformin - therapeutic use | Colonic Neoplasms - drug therapy | Humans | Gene Expression Regulation, Neoplastic | Male | Obesity - genetics | Ovarian Neoplasms - genetics | Prostatic Neoplasms - genetics | Endometrial Neoplasms - genetics | Endocrine System - drug effects | Female | Ovarian Neoplasms - drug therapy | Prostatic Neoplasms - drug therapy | Hypoglycemic Agents - therapeutic use | Endometrial Neoplasms - enzymology | Metformin - pharmacology | Ovarian Neoplasms - enzymology | Endocrine System - pathology | Hypoglycemic Agents - pharmacology | Cell Transformation, Neoplastic | Prostatic Neoplasms - enzymology | Endometrial Neoplasms - drug therapy | Colonic Neoplasms - enzymology | Obesity - enzymology | Endocrine System - enzymology | AMP-Activated Protein Kinases - genetics | Biological Factors - pharmacology | Physiological aspects | Care and treatment | Tumor proteins | Cancer | Index Medicus | Breast
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5. Full Text Regulation of the Activity of p38 Mitogen-Activated Protein Kinase by Akt in Cancer and Adenoviral Protein E1A-Mediated Sensitization to Apoptosis
by Yong Liao and Mien-Chie Hung
Molecular and Cellular Biology, ISSN 0270-7306, 10/2003, Volume 23, Issue 19, pp. 6836 - 6848
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Neoplasms - metabolism | Prostatic Neoplasms - metabolism | Colonic Neoplasms - virology | Phosphorylation | Adenovirus E1A Proteins - chemistry | Humans | Protein-Serine-Threonine Kinases | Gene Expression Regulation, Neoplastic | Ovarian Neoplasms - pathology | Male | Prostatic Neoplasms - virology | Colonic Neoplasms - metabolism | Breast Neoplasms - metabolism | Neoplasms - virology | Breast Neoplasms - enzymology | Neoplasms - genetics | Ovarian Neoplasms - virology | Adenovirus E1A Proteins - metabolism | Gene Deletion | Adenoviridae - genetics | Female | Ovarian Neoplasms - metabolism | p38 Mitogen-Activated Protein Kinases | Protein Structure, Tertiary | Proto-Oncogene Proteins - metabolism | Cell Line | Prostatic Neoplasms - pathology | Neoplasms - enzymology | Ovarian Neoplasms - enzymology | Breast Neoplasms - virology | Gene Expression Regulation, Enzymologic | Proto-Oncogene Proteins c-akt | Breast Neoplasms - pathology | Colonic Neoplasms - pathology | Prostatic Neoplasms - enzymology | Mitogen-Activated Protein Kinases - genetics | Colonic Neoplasms - enzymology | Adenoviridae - metabolism | Neoplasms - pathology | Apoptosis | Mitogen-Activated Protein Kinases - metabolism | Index Medicus | Cell Growth and Development
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6. Full Text Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH
by Chiche, Johanna and Ilc, Karine and Laferrière, Julie and Trottier, Eric and Dayan, Frédéric and Mazure, Nathalie M and Brahimi-Horn, M. Christiane and Pouysségur, Jacques
Cancer research (Chicago, Ill.), ISSN 0008-5472, 01/2009, Volume 69, Issue 1, pp. 358 - 368
Life Sciences & Biomedicine | Oncology | Science & Technology | Biological and medical sciences | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Tumors | Cell Hypoxia - physiology | Carbonic Anhydrases - biosynthesis | Cricetulus | Humans | Antigens, Neoplasm - biosynthesis | Cell Growth Processes - physiology | Cytoplasm - metabolism | Male | Acidosis - metabolism | Colonic Neoplasms - metabolism | Carbonic Anhydrases - metabolism | Antigens, Neoplasm - metabolism | Fibroblasts | Spheroids, Cellular | Carbonic Anhydrase IX | Cytoplasm - enzymology | Cricetinae | Enzyme Induction | Animals | Mice, Nude | Colonic Neoplasms - pathology | Cell Line, Tumor | Colonic Neoplasms - enzymology | Mice | Acidosis - enzymology | Hydrogen-Ion Concentration | Index Medicus | Antigens, Neoplasm | Carbonic Anhydrases | Cell Growth Processes | Cell Hypoxia | Life Sciences | Development Biology | Acidosis | Cytoplasm | Colonic Neoplasms
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7. Full Text MerTK inhibition in tumor leukocytes decreases tumor growth and metastasis
by Cook, Rebecca S and Jacobsen, Kristen M and Wofford, Anne M and DeRyckere, Deborah and Stanford, Jamie and Prieto, Anne L and Redente, Elizabeth and Sandahl, Melissa and Hunter, Debra M and Strunk, Karen E and Graham, Douglas K and Earp Iii, H. Shelton
The Journal of clinical investigation, ISSN 0021-9738, 08/2013, Volume 123, Issue 8, pp. 3231 - 3242
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Mammary Neoplasms, Experimental - immunology | Neoplasm Transplantation | Gene Expression Regulation, Neoplastic | Transcriptome | Tumor Microenvironment | Male | Disease Resistance - immunology | Leukocytes - enzymology | Melanoma, Experimental - immunology | Colonic Neoplasms - immunology | c-Mer Tyrosine Kinase | Mammary Neoplasms, Experimental - pathology | Female | Proto-Oncogene Proteins | Cytokines - genetics | Mammary Neoplasms, Experimental - enzymology | Melanoma, Experimental - enzymology | Cytokines - metabolism | Mice, Inbred C57BL | Melanoma, Experimental - pathology | Tumor Burden | Receptor Protein-Tyrosine Kinases | CD8-Positive T-Lymphocytes - enzymology | Mice, Knockout | Animals | Colonic Neoplasms - pathology | Colonic Neoplasms - enzymology | Mice | Control | Growth | Physiological aspects | Genetic aspects | Research | Leukocytes | Metastasis | Tyrosine metabolism | Tumors | Wound healing | Lymphocytes | Rodents | Breast cancer | Kinases | Immune system | Index Medicus | Abridged Index Medicus
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8. Full Text Expression of drug pathway proteins is independent of tumour type
by Zhang, W and Shannon, WD and Duncan, J and Scheffer, GL and Scheper, RJ and McLeod, HL
The Journal of pathology, ISSN 0022-3417, 06/2006, Volume 209, Issue 2, pp. 213 - 219
irinotecan | immunohistochemistry | tissue microarray | chemotherapy | Immunohistochemistry | Irinotecan | Tissue microarray | Chemotherapy | Pathology | Oncology | Life Sciences & Biomedicine | Science & Technology | Biological and medical sciences | Investigative techniques, diagnostic techniques (general aspects) | Medical sciences | Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques | Prostatic Neoplasms - chemistry | Antineoplastic Agents, Phytogenic - analysis | Humans | Melanoma - enzymology | Drug Resistance, Neoplasm | Male | Tissue Array Analysis - methods | Neoplasms - chemistry | Breast Neoplasms - chemistry | Breast Neoplasms - enzymology | Lymphoma - enzymology | Colonic Neoplasms - chemistry | Female | Adenocarcinoma - chemistry | Melanoma - chemistry | Camptothecin - analogs & derivatives | Brain Neoplasms - chemistry | Brain Neoplasms - enzymology | Cytochrome P-450 Enzyme System - analysis | Multidrug Resistance-Associated Proteins - analysis | Ovarian Neoplasms - chemistry | Lung Neoplasms - enzymology | Lung Neoplasms - chemistry | Adenocarcinoma - enzymology | Neoplasms - enzymology | Enzyme Inhibitors - analysis | Lymphoma - chemistry | Ovarian Neoplasms - enzymology | Immunohistochemistry - methods | Camptothecin - analysis | Prostatic Neoplasms - enzymology | Neoplasm Proteins - analysis | Colonic Neoplasms - enzymology | Index Medicus
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9. Full Text Glucose-6-Phosphate Dehydrogenase Is Not Essential for K-Ras-Driven Tumor Growth or Metastasis
by Ghergurovich, Jonathan M and Esposito, Mark and Chen, Zihong and Wang, Joshua Z and Bhatt, Vrushank and Lan, Taijin and White, Eileen and Kang, Yibin and Guo, Jessie Yanxiang and Rabinowitz, Joshua D
Cancer research (Chicago, Ill.), ISSN 0008-5472, 09/2020, Volume 80, Issue 18, pp. 3820 - 3829
Life Sciences & Biomedicine | Oncology | Science & Technology | Neoplasm Transplantation | Colonic Neoplasms - genetics | Cell Proliferation | Oxidative Stress | Humans | Glucosephosphate Dehydrogenase - physiology | Gene Knockdown Techniques | Genes, ras - physiology | Lung Neoplasms - secondary | Triple Negative Breast Neoplasms - pathology | Female | Triple Negative Breast Neoplasms - enzymology | Disease Models, Animal | Lung Neoplasms - genetics | Lung Neoplasms - enzymology | Carcinoma, Non-Small-Cell Lung - genetics | HCT116 Cells | Animals | Triple Negative Breast Neoplasms - genetics | Mice, Nude | Colonic Neoplasms - pathology | Neoplastic Cells, Circulating | Cell Line, Tumor | Colonic Neoplasms - enzymology | Mice | Glucosephosphate Dehydrogenase - genetics | Index Medicus
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