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Molecular and Cellular Biology, ISSN 0270-7306, 10/2003, Volume 23, Issue 19, pp. 6836 - 6848
Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
BREAST-CANCER | ONCOGENE-DEPENDENT APOPTOSIS | P53-DEPENDENT APOPTOSIS | SIGNALING PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | STRESS-RESPONSE | TUMOR-SUPPRESSOR | CELL-CYCLE | TYROSINE KINASES | OVARIAN-CANCER | INDUCE APOPTOSIS | CELL BIOLOGY | Neoplasms - metabolism | Prostatic Neoplasms - metabolism | Colonic Neoplasms - virology | Phosphorylation | Adenovirus E1A Proteins - chemistry | Humans | Protein-Serine-Threonine Kinases | Gene Expression Regulation, Neoplastic | Ovarian Neoplasms - pathology | Male | Prostatic Neoplasms - virology | Colonic Neoplasms - metabolism | Breast Neoplasms - metabolism | Neoplasms - virology | Breast Neoplasms - enzymology | Neoplasms - genetics | Ovarian Neoplasms - virology | Adenovirus E1A Proteins - metabolism | Gene Deletion | Adenoviridae - genetics | Female | Ovarian Neoplasms - metabolism | p38 Mitogen-Activated Protein Kinases | Protein Structure, Tertiary | Proto-Oncogene Proteins - metabolism | Cell Line | Prostatic Neoplasms - pathology | Neoplasms - enzymology | Ovarian Neoplasms - enzymology | Breast Neoplasms - virology | Gene Expression Regulation, Enzymologic | Proto-Oncogene Proteins c-akt | Breast Neoplasms - pathology | Colonic Neoplasms - pathology | Prostatic Neoplasms - enzymology | Mitogen-Activated Protein Kinases - genetics | Colonic Neoplasms - enzymology | Adenoviridae - metabolism | Neoplasms - pathology | Apoptosis | Mitogen-Activated Protein Kinases - metabolism | Index Medicus | Cell Growth and Development
Journal Article
Cancer Cell, ISSN 1535-6108, 2011, Volume 19, Issue 1, pp. 125 - 137
Metastasis is responsible for most cancer deaths. Here, we show that (or ) gene functions as an endogenous metastasis suppressor. Expression of Aes was... 
COMPLEX | GENE | REPRESSION | ONCOLOGY | PATHWAY | DISEASE | RECEPTOR | MICE | INDUCTION | TUMORIGENESIS | MOUSE MODELS | CELL BIOLOGY | Gene Expression - genetics | Receptors, Notch - metabolism | Humans | Neoplasm Invasiveness - prevention & control | Colonic Neoplasms - metabolism | Receptors, Notch - antagonists & inhibitors | Liver Neoplasms - pathology | Transendothelial and Transepithelial Migration - physiology | Liver Neoplasms - secondary | Immunoglobulin J Recombination Signal Sequence-Binding Protein - genetics | Repressor Proteins - metabolism | Nuclear Matrix - metabolism | HCT116 Cells | Repressor Proteins - genetics | Mice, Transgenic | Down-Regulation - genetics | Intestinal Polyposis - metabolism | Lung Neoplasms - prevention & control | Signal Transduction - drug effects | Mice, Nude | Models, Biological | Cell Line, Tumor | Ligands | Mice | Mice, Inbred BALB C | Colonic Neoplasms - drug therapy | Lung Neoplasms - pathology | Lung Neoplasms - secondary | Mice, Mutant Strains | Neoplasm Invasiveness - pathology | Neoplasm Metastasis - prevention & control | Immunoglobulin J Recombination Signal Sequence-Binding Protein - metabolism | Intestinal Polyposis - pathology | Benzodiazepinones - pharmacology | Mice, Inbred C57BL | Stromal Cells - metabolism | Intestinal Polyposis - drug therapy | Receptor, Notch1 - metabolism | Transcription Factors - genetics | Transcription Factors - metabolism | Neoplasm Metastasis - genetics | Animals | Neoplasm Metastasis - pathology | Colonic Neoplasms - pathology | Signal Transduction - physiology | Co-Repressor Proteins | Neoplasm Invasiveness - genetics | Benzodiazepinones - therapeutic use | Gene Silencing - physiology | Index Medicus
Journal Article
Molecular & Cellular Proteomics, ISSN 1535-9476, 07/2008, Volume 7, Issue 7, pp. 1214 - 1224
Journal Article
American Journal of Public Health, ISSN 0090-0036, 09/2013, Volume 103, Issue 9, pp. 1708 - 1714
Objectives. We examined cancer incidence in an expanded cohort of Swedish chimney sweeps. Methods. We added male chimney sweep trade union members (1981-2006)... 
MORTALITY | OCCUPATIONAL EXPOSURES | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | MELANOMA | POLYCYCLIC AROMATIC-HYDROCARBONS | WORKERS | FOLLOW-UP | NORDIC COUNTRIES | RISK | ESOPHAGEAL CANCER | EPIDEMIOLOGY | Esophageal Neoplasms - etiology | Neoplasms - etiology | Humans | Occupational Diseases - etiology | Male | Esophageal Neoplasms - epidemiology | Incidence | Liver Neoplasms - etiology | Liver Neoplasms - epidemiology | Lung Neoplasms - etiology | Urinary Bladder Neoplasms - epidemiology | Colonic Neoplasms - etiology | Pleural Neoplasms - epidemiology | Occupational Exposure - adverse effects | Urinary Bladder Neoplasms - etiology | Colonic Neoplasms - epidemiology | Soot - adverse effects | Sweden - epidemiology | Skin Neoplasms - epidemiology | Pleural Neoplasms - etiology | Lung Neoplasms - epidemiology | Asbestos - adverse effects | Poisson Distribution | Skin Neoplasms - etiology | Occupational Diseases - epidemiology | Neoplasms - epidemiology | Occupational health and safety | Research | Health aspects | Statistics | Risk factors | Chimney sweeps | Cancer | Cardiovascular disease | Occupational safety | Health risk assessment | Mortality | Skin cancer | Index Medicus | Abridged Index Medicus | Research and Practice | Hälsovetenskap | Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi | Medical and Health Sciences | Medicin och hälsovetenskap | Public Health, Global Health, Social Medicine and Epidemiology | Health Sciences
Journal Article
Journal Article
Gastroenterology, ISSN 0016-5085, 2017, Volume 152, Issue 5, pp. e12 - e13
Journal Article
Cancer Research, ISSN 0008-5472, 09/2010, Volume 70, Issue 17, pp. 6804 - 6814
Mutational activation of KRAS is a common event in human tumors. Identification of the key signaling pathways downstream of mutant KRAS is essential for our... 
ACTIVATED PROTEIN-KINASE | EPITHELIAL-CELLS | PI3K | GENE | ONCOLOGY | RAS | PLECKSTRIN-HOMOLOGY-DOMAIN | AKT | MEK INHIBITORS | PHASE-I | HUMAN CANCER | Cyclin D1 - metabolism | Lung Neoplasms - drug therapy | ras Proteins - genetics | Colonic Neoplasms - genetics | Proto-Oncogene Proteins p21(ras) | Diphenylamine - pharmacology | Pancreatic Neoplasms - metabolism | Colonic Neoplasms - drug therapy | Humans | Lung Neoplasms - metabolism | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | ras Proteins - metabolism | Lung Neoplasms - pathology | Phosphatidylinositol 3-Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Colonic Neoplasms - metabolism | Pancreatic Neoplasms - drug therapy | Diphenylamine - analogs & derivatives | Benzamides - pharmacology | Cell Growth Processes - genetics | MAP Kinase Kinase Kinases - antagonists & inhibitors | Proto-Oncogene Proteins c-akt - metabolism | Lung Neoplasms - genetics | Proto-Oncogene Proteins - metabolism | HCT116 Cells | Pancreatic Neoplasms - pathology | Pancreatic Neoplasms - genetics | Proto-Oncogene Proteins - genetics | Cyclin D1 - biosynthesis | MAP Kinase Kinase Kinases - metabolism | Gene Knockout Techniques | Phosphatidylinositol 3-Kinases - genetics | Animals | Class I Phosphatidylinositol 3-Kinases | MAP Kinase Signaling System - drug effects | Cyclin D1 - genetics | Colonic Neoplasms - pathology | Alleles | Cell Line, Tumor | Mice | Mutation | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Index Medicus
Journal Article
Gastroenterology, ISSN 0016-5085, 10/2000, Volume 119, Issue 4, pp. 921 - 928
Journal Article
Annals of Vascular Surgery, ISSN 0890-5096, 2015, Volume 29, Issue 5, pp. 1007 - 1014
Background An aggressive surgical approach to locally advanced malignancy is being increasingly used in the absence of distant metastatic disease. This... 
Surgery | RADICAL NEPHRECTOMY | PANCREATICODUODENECTOMY | SURGERY | SINGLE-CENTER EXPERIENCE | PORTAL-VEIN | BLOC VASCULAR RESECTION | VENA-CAVA THROMBECTOMY | PERIPHERAL VASCULAR DISEASE | PANCREATIC ADENOCARCINOMA | OUTCOMES | CANCER | RENAL-CELL CARCINOMA | Digestive System Neoplasms - mortality | Humans | Middle Aged | Patient Care Team | Male | Veins - surgery | Blood Loss, Surgical | Operative Time | Colonic Neoplasms - surgery | Kidney Neoplasms - surgery | Adrenal Gland Neoplasms - mortality | Time Factors | Vascular Surgical Procedures - mortality | Aged, 80 and over | Portal Vein - pathology | Retroperitoneal Neoplasms - pathology | Pancreatic Neoplasms - pathology | Risk Factors | Portal Vein - surgery | Veins - physiopathology | Digestive System Neoplasms - surgery | Survival Analysis | Veins - pathology | Vascular Patency | Adrenal Gland Neoplasms - surgery | Vena Cava, Inferior - surgery | Mesenteric Veins - pathology | Mesenteric Veins - surgery | Neoplasm, Residual | Retroperitoneal Neoplasms - mortality | Digestive System Neoplasms - pathology | Vena Cava, Inferior - pathology | Adult | Female | Retrospective Studies | Retroperitoneal Neoplasms - surgery | Adrenal Gland Neoplasms - pathology | Length of Stay | Neoplasm Invasiveness | Pancreatic Neoplasms - surgery | Hospitals, University | Treatment Outcome | Kidney Neoplasms - mortality | Michigan | Reconstructive Surgical Procedures - mortality | Vascular Surgical Procedures - adverse effects | Colonic Neoplasms - pathology | Reconstructive Surgical Procedures - adverse effects | Kidney Neoplasms - pathology | Aged | Gallbladder Neoplasms - pathology | Gallbladder Neoplasms - surgery | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2015, Volume 10, Issue 8, pp. e0134929 - e0134929
Novel biomarkers for cancer diagnosis and therapy selection are urgently needed to facilitate early detection and improve therapy outcomes. We have previously... 
LUNG-CANCER | APOPTOSIS | CAMPTOTHECIN | ILLEGITIMATE RECOMBINATION | MULTIDISCIPLINARY SCIENCES | PROTEIN-KINASE CK2 | DRUGS | SQUAMOUS-CELL CARCINOMA | DNA TOPOISOMERASES | PROLIFERATION | ASSOCIATION | Neoplasms - metabolism | Lung Neoplasms - drug therapy | Colonic Neoplasms - genetics | Phosphorylation | Colonic Neoplasms - drug therapy | Humans | Lung Neoplasms - metabolism | Colonic Neoplasms - diagnosis | Molecular Sequence Data | Carcinoma, Non-Small-Cell Lung - diagnosis | Neoplasms - diagnosis | Colonic Neoplasms - metabolism | Ovarian Neoplasms - genetics | Neoplasms - genetics | Biomarkers, Tumor - metabolism | Female | Lung - metabolism | Ovarian Neoplasms - metabolism | Antineoplastic Agents, Phytogenic - therapeutic use | Ovarian Neoplasms - drug therapy | Camptothecin - analogs & derivatives | Lung Neoplasms - genetics | Amino Acid Sequence | Gene Expression | Lung - pathology | Camptothecin - therapeutic use | DNA Topoisomerases, Type I - metabolism | Carcinoma, Non-Small-Cell Lung - genetics | Ovarian Neoplasms - diagnosis | Carcinoma, Non-Small-Cell Lung - metabolism | DNA Topoisomerases, Type I - genetics | Topotecan - therapeutic use | Serine - metabolism | Neoplasms - drug therapy | Lung - drug effects | Cell Line, Tumor | Biomarkers, Tumor - genetics | Carcinoma, Non-Small-Cell Lung - drug therapy | Lung Neoplasms - diagnosis | Research | Biological markers | Oncology, Experimental | DNA topoisomerase I | Cell lines | Cancer | Drugs | Camptothecin | Therapy | Biotechnology | Correlation | Lung | Serine | Lung cancer | Clinical trials | Oncology | Kinases | Cancer therapies | Proteins | Colon cancer | Plant tissues | Bioindicators | Colon | Diagnosis | Deoxyribonucleic acid--DNA | Medical research | Non-small cell lung carcinoma | Topotecan | Irinotecan | Medical prognosis | Biomarkers | Tumors | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Experimental Cell Research, ISSN 0014-4827, 12/2017, Volume 361, Issue 2, pp. 308 - 315
We and others have previously reported a correlation between high phosphodiesterase 3 A ( ) expression and selective sensitivity to phosphodiesterase (PDE)... 
PDE3A | Therapy | Biomarker | Repositioning | Cancer | ONCOLOGY | PDE3 | DRUG DEVELOPMENT | GENE-EXPRESSION | CAMP EARLY REPRESSOR | CELL BIOLOGY | Lung Neoplasms - drug therapy | Colonic Neoplasms - genetics | Cyclic Nucleotide Phosphodiesterases, Type 3 - genetics | Skin Neoplasms - drug therapy | Colonic Neoplasms - drug therapy | Humans | Lung Neoplasms - metabolism | Middle Aged | Lung Neoplasms - pathology | Male | Neoplasm Proteins - antagonists & inhibitors | Pyridazines - pharmacology | Molecular Targeted Therapy | Neoplasm Proteins - metabolism | RNA, Messenger - metabolism | Colonic Neoplasms - metabolism | Organoplatinum Compounds - pharmacology | Melanoma - genetics | Gastrointestinal Stromal Tumors - pathology | RNA, Messenger - antagonists & inhibitors | Biomarkers, Tumor - metabolism | Adult | Female | Antineoplastic Agents - pharmacology | Cyclic Nucleotide Phosphodiesterases, Type 3 - metabolism | Neoplasm Proteins - genetics | Gastrointestinal Stromal Tumors - genetics | Lung Neoplasms - genetics | Melanoma - metabolism | Skin Neoplasms - pathology | Gene Expression | RNA, Messenger - genetics | Phosphodiesterase Inhibitors - pharmacology | Melanoma - pathology | Organ Specificity | Skin Neoplasms - metabolism | Carrier Proteins - genetics | Carrier Proteins - metabolism | Gastrointestinal Stromal Tumors - drug therapy | Colonic Neoplasms - pathology | Melanoma - drug therapy | Skin Neoplasms - genetics | Cell Line, Tumor | Gastrointestinal Stromal Tumors - metabolism | Aged | Biomarkers, Tumor - genetics | Quinazolines - pharmacology | RNA | Analysis | Genes | Diagnosis | Gene expression | Ovarian cancer | Index Medicus | Clinical Medicine | Medical and Health Sciences | Cancer and Oncology | Klinisk medicin | Medicin och hälsovetenskap | Cancer och onkologi
Journal Article