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Lancet Oncology, The, ISSN 1470-2045, 2013, Volume 14, Issue 6, pp. 481 - 489
Summary Background EGFR overexpression occurs in 27–55% of oesophagogastric adenocarcinomas, and correlates with poor prognosis. We aimed to assess addition of... 
Hematology, Oncology and Palliative Medicine | GROWTH-FACTOR RECEPTOR | 1ST-LINE TREATMENT | CETUXIMAB | PROSPECTIVE MULTICENTER | ONCOLOGY | GASTRIC-CANCER | PROGNOSTIC-SIGNIFICANCE | CELL-LINES | METASTATIC COLORECTAL-CANCER | ESOPHAGEAL ADENOCARCINOMA | III TRIAL | Multivariate Analysis | Adenocarcinoma - pathology | Capecitabine | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Stomach Neoplasms - pathology | Epirubicin - administration & dosage | Molecular Targeted Therapy | Esophageal Neoplasms - pathology | Early Termination of Clinical Trials | Organoplatinum Compounds - administration & dosage | Receptor, Epidermal Growth Factor - metabolism | Fluorouracil - administration & dosage | Time Factors | Biomarkers, Tumor - metabolism | Esophageal Neoplasms - mortality | Female | Biomarkers, Tumor - antagonists & inhibitors | Odds Ratio | Stomach Neoplasms - enzymology | Fluorouracil - analogs & derivatives | Deoxycytidine - administration & dosage | Adenocarcinoma - enzymology | Kaplan-Meier Estimate | Proportional Hazards Models | Logistic Models | Treatment Outcome | United Kingdom | Stomach Neoplasms - drug therapy | Chi-Square Distribution | Adenocarcinoma - drug therapy | Disease-Free Survival | Protein Kinase Inhibitors - administration & dosage | Esophageal Neoplasms - enzymology | Antibodies, Monoclonal - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Intention to Treat Analysis | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Aged | Esophageal Neoplasms - drug therapy | Stomach Neoplasms - mortality | Deoxycytidine - analogs & derivatives | Adenocarcinoma - mortality | Care and treatment | Anthracyclines | Product development | Cancer | Index Medicus
Journal Article
Journal Article
Journal Article
Oncogene, ISSN 0950-9232, 04/2008, Volume 27, Issue 18, pp. 2635 - 2647
TMPRSS4 is a novel type II transmembrane serine protease found at the cell surface that is highly expressed in pancreatic, colon and gastric cancer tissues.... 
Serine protease | Metastasis | E-cadherin | EMT | Invasion | TMPRSS4 | PROSTATE | MATRIPTASE | SURFACE PROTEOLYTIC-ENZYMES | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | serine protease | CELL BIOLOGY | BREAST-CANCER CELLS | MATRIX METALLOPROTEINASES | invasion | PLASMINOGEN-ACTIVATOR | ONCOLOGY | metastasis | GENETICS & HEREDITY | TRANSMEMBRANE SERINE PROTEASES | EXPRESSION | RNA, Small Interfering - genetics | Cadherins - metabolism | Humans | Neoplasm Proteins - antagonists & inhibitors | Cell Movement - genetics | Neoplasm Metastasis | Serine Endopeptidases - genetics | Liver Neoplasms - pathology | Cadherins - genetics | Liver Neoplasms - enzymology | Liver Neoplasms - secondary | Neoplasm Proteins - genetics | Gene Expression Regulation, Neoplastic - genetics | Lung Neoplasms - enzymology | Liver Neoplasms - genetics | Serine Endopeptidases - biosynthesis | Membrane Proteins - genetics | Epithelial Cells - pathology | Lung Neoplasms - therapy | Gastrointestinal Neoplasms - enzymology | Gastrointestinal Neoplasms - therapy | Cell Adhesion | Cell Movement - drug effects | Membrane Proteins - biosynthesis | Membrane Proteins - antagonists & inhibitors | Gene Expression Regulation, Enzymologic - genetics | Mice, Nude | Cell Communication - drug effects | Epithelial Cells - enzymology | Cell Line, Tumor | Biomarkers, Tumor - genetics | Cadherins - antagonists & inhibitors | Mice | RNA-Binding Proteins - metabolism | Gene Expression Regulation, Enzymologic - drug effects | Neoplasm Transplantation | RNA-Binding Proteins - genetics | Gastrointestinal Neoplasms - genetics | Lung Neoplasms - pathology | Liver Neoplasms - therapy | Gastrointestinal Neoplasms - pathology | Gene Expression Regulation, Neoplastic - drug effects | Lung Neoplasms - genetics | Neoplasm Invasiveness | Neoplasm Proteins - biosynthesis | Cell Communication - genetics | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Animals | Biomarkers, Tumor - biosynthesis | Care and treatment | Control | Proteases | Cancer cells | Physiological aspects | Genetic aspects | Research | Risk factors | Oncology | Genetics | Cellular biology | Pancreatic cancer | Colorectal cancer | Index Medicus
Journal Article
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 06/2010, Volume 28, Issue 17, pp. 2817 - 2823
Journal Article
International Journal of Clinical and Experimental Pathology, ISSN 1936-2625, 2014, Volume 7, Issue 8, pp. 5057 - 5070
Journal Article
Cancer Research, ISSN 0008-5472, 10/2009, Volume 69, Issue 20, pp. 8208 - 8215
Journal Article
Nature, ISSN 0028-0836, 03/2012, Volume 483, Issue 7387, pp. 100 - 104
Inhibition of the BRAF(V600E) oncoprotein by the small-molecule drug PLX4032 (vemurafenib) is highly effective in the treatment of melanoma(1). However, colon... 
PANITUMUMAB | TARGET | CETUXIMAB | MELANOMA | BRAF MUTATIONS | MULTIDISCIPLINARY SCIENCES | PAPILLARY THYROID-CARCINOMA | KRAS | METASTATIC COLORECTAL-CANCER | Erlotinib Hydrochloride | Receptor, Epidermal Growth Factor - agonists | Apoptosis - drug effects | Colorectal Neoplasms - genetics | Humans | Antineoplastic Agents - therapeutic use | Antibodies, Monoclonal, Humanized | Receptor, Epidermal Growth Factor - metabolism | RNA Interference | Colorectal Neoplasms - drug therapy | HEK293 Cells | Female | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Cetuximab | Proto-Oncogene Proteins B-raf - metabolism | Proto-Oncogene Proteins B-raf - chemistry | Melanoma - metabolism | Colorectal Neoplasms - enzymology | Antibodies, Monoclonal - pharmacology | Enzyme Activation - drug effects | Sulfonamides - pharmacology | Drug Synergism | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Xenograft Model Antitumor Assays | Animals | Sulfonamides - therapeutic use | Protein Kinase Inhibitors - therapeutic use | Proto-Oncogene Proteins B-raf - genetics | Quinazolines - therapeutic use | Melanoma - drug therapy | Cell Line, Tumor | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Feedback, Physiological - drug effects | Indoles - therapeutic use | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Colorectal Neoplasms - pathology | Quinazolines - pharmacology | Drug Resistance, Neoplasm - drug effects | Proteins | Library collections | Studies | Phosphorylation | Kinases | Tumors | Index Medicus
Journal Article