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1. Full Text Understanding the role of primary tumour localisation in colorectal cancer treatment and outcomes
by Stintzing, Sebastian and Tejpar, Sabine and Gibbs, Peter and Thiebach, Lars and Lenz, Heinz-Josef
European journal of cancer (1990), ISSN 0959-8049, 10/2017, Volume 84, pp. 69 - 80
Hindgut | Midgut | Colorectal carcinoma | Predictive | Metastatic | Colon | Prognostic | Life Sciences & Biomedicine | Oncology | Science & Technology | Predictive Value of Tests | Receptor, Epidermal Growth Factor - genetics | Colonic Neoplasms - genetics | Colonic Neoplasms - drug therapy | Colorectal Neoplasms - genetics | Humans | Antineoplastic Agents - therapeutic use | Molecular Diagnostic Techniques | Neoplasm Metastasis | Receptor, Epidermal Growth Factor - metabolism | Rectal Neoplasms - genetics | Colorectal Neoplasms - drug therapy | Biomarkers, Tumor - metabolism | Rectal Neoplasms - pathology | Biomarkers, Tumor - antagonists & inhibitors | Rectal Neoplasms - drug therapy | Precision Medicine | Colorectal Neoplasms - enzymology | Gastrointestinal Microbiome | Treatment Outcome | Rectal Neoplasms - enzymology | Protein Kinase Inhibitors - therapeutic use | Colonic Neoplasms - pathology | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Biomarkers, Tumor - genetics | Colonic Neoplasms - enzymology | Mutation | Colorectal Neoplasms - pathology | Medical research | Care and treatment | Colorectal cancer | Medicine, Experimental | Drug therapy | Tumors | Cancer | Epidermal growth factor | Metastasis | Spleen | Impact prediction | Microbiomes | Patients | Flexing | Molecular chains | Metastases | Rectum | Index Medicus
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2. Full Text TMPRSS4 promotes invasion, migration and metastasis of human tumor cells by facilitating an epithelial-mesenchymal transition
by Jung, H and Lee, K.P and Park, S.J and Park, J.H and Jang, Y.-S and Choi, S.-Y and Jung, J.-G and Jo, K and Park, D.Y and Yoon, J.H and Park, J.-H and Lim, D.-S and Hong, G.-R and Choi, C and Park, Y.-K and Lee, J.W and Hong, H.J and Kim, S and Park, Y.W
Oncogene, ISSN 0950-9232, 04/2008, Volume 27, Issue 18, pp. 2635 - 2647
Serine protease | Metastasis | E-cadherin | EMT | Invasion | TMPRSS4 | Biochemistry & Molecular Biology | Oncology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Cell physiology | Molecular and cellular biology | Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes | RNA, Small Interfering - genetics | Cadherins - metabolism | Humans | Neoplasm Proteins - antagonists & inhibitors | Cell Movement - genetics | Neoplasm Metastasis | Serine Endopeptidases - genetics | Liver Neoplasms - pathology | Cadherins - genetics | Liver Neoplasms - enzymology | Liver Neoplasms - secondary | Neoplasm Proteins - genetics | Gene Expression Regulation, Neoplastic - genetics | Lung Neoplasms - enzymology | Liver Neoplasms - genetics | Serine Endopeptidases - biosynthesis | Membrane Proteins - genetics | Epithelial Cells - pathology | Lung Neoplasms - therapy | Gastrointestinal Neoplasms - enzymology | Gastrointestinal Neoplasms - therapy | Cell Adhesion | Cell Movement - drug effects | Membrane Proteins - biosynthesis | Membrane Proteins - antagonists & inhibitors | Gene Expression Regulation, Enzymologic - genetics | Mice, Nude | Cell Communication - drug effects | Epithelial Cells - enzymology | Cell Line, Tumor | Biomarkers, Tumor - genetics | Cadherins - antagonists & inhibitors | Mice | RNA-Binding Proteins - metabolism | Gene Expression Regulation, Enzymologic - drug effects | Neoplasm Transplantation | RNA-Binding Proteins - genetics | Gastrointestinal Neoplasms - genetics | Lung Neoplasms - pathology | Liver Neoplasms - therapy | Gastrointestinal Neoplasms - pathology | Gene Expression Regulation, Neoplastic - drug effects | Lung Neoplasms - genetics | Neoplasm Invasiveness | Neoplasm Proteins - biosynthesis | Cell Communication - genetics | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Animals | Biomarkers, Tumor - biosynthesis | Care and treatment | Control | Proteases | Cancer cells | Physiological aspects | Genetic aspects | Research | Risk factors | Genetics | Cellular biology | Pancreatic cancer | Colorectal cancer | Index Medicus
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3. Full Text Elevated cleaved caspase-3 is associated with shortened overall survival in several cancer types
by Hu, Qian and Hu, Qian and Peng, Jing and Peng, Jing and Liu, Weiping and He, Xiaoli and Cui, Ling and Cui, Ling and Chen, Xinlian and Chen, Xinlian and Yang, Mei and Yang, Mei and Liu, Hongqian and Liu, Hongqian and Liu, Shanling and Liu, Shanling and Wang, He and Wang, He
International journal of clinical and experimental pathology, ISSN 1936-2625, 2014, Volume 7, Issue 8, pp. 5057 - 5070
Cleaved caspase-3 expression | Prognosis | Overall survival of cancer patients | Multivariate Cox proportional hazards model analysis | Pathology | Oncology | Life Sciences & Biomedicine | Science & Technology | Immunohistochemistry | Humans | Middle Aged | Caspase 3 - metabolism | Ovarian Neoplasms - pathology | Male | Stomach Neoplasms - pathology | Uterine Cervical Neoplasms - pathology | Ovarian Neoplasms - mortality | Young Adult | Aged, 80 and over | Adult | Female | Uterine Cervical Neoplasms - mortality | Colorectal Neoplasms - mortality | Stomach Neoplasms - enzymology | Colorectal Neoplasms - enzymology | Uterine Cervical Neoplasms - enzymology | Biomarkers, Tumor - analysis | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Neoplasms - enzymology | Neoplasms - mortality | Disease Progression | Ovarian Neoplasms - enzymology | Adolescent | Caspase 3 - analysis | Aged | Apoptosis - physiology | Colorectal Neoplasms - pathology | Neoplasms - pathology | Stomach Neoplasms - mortality | Index Medicus
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4. Full Text Glucose-6-phosphate dehydrogenase deficiency reduces susceptibility to cancer of endodermal origin
by Pes, Giovanni Mario and Errigo, Alessandra and Soro, Sara and Longo, Nunzio Pio and Dore, Maria Pina
Acta oncologica, ISSN 0284-186X, 09/2019, Volume 58, Issue 9, pp. 1205 - 1211
Life Sciences & Biomedicine | Oncology | Science & Technology | Stomach Neoplasms - enzymology | Colorectal Neoplasms - enzymology | Confidence Intervals | Glucosephosphate Dehydrogenase - blood | Disease Susceptibility | Lung Neoplasms - enzymology | Bone Marrow Neoplasms - enzymology | Glucosephosphate Dehydrogenase Deficiency - epidemiology | Humans | Middle Aged | Neoplasms - enzymology | Linear Models | Male | Carcinoma, Hepatocellular - enzymology | Organ Specificity | Case-Control Studies | Breast Neoplasms - enzymology | Aged, 80 and over | Prostatic Neoplasms - enzymology | Adult | Female | Aged | Retrospective Studies | Liver Neoplasms - enzymology | Index Medicus
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5. The dilemma: Does tissue expression of cathepsin D reflect tumor malignancy? the question: Does the assay truly mirror cathepsin D mis-function in the tumor?
by Nicotra, Giuseppina and Castino, Roberta and Follo, Carlo and Peracchio, Claudia and Valente, Guido and Isidoro, Ciro
Cancer biomarkers : section A of Disease markers, ISSN 1574-0153, 2010, Volume 7, Issue 1, pp. 47 - 64
cell death | tumor marker | metastasis | prognosis | proteolysis | Lysosome | Life Sciences & Biomedicine | Oncology | Science & Technology | Golgi Apparatus - enzymology | Stomach Neoplasms - enzymology | Colorectal Neoplasms - enzymology | Lung Neoplasms - enzymology | Neoplasms - etiology | Humans | Urinary Bladder Neoplasms - enzymology | Nervous System Neoplasms - enzymology | Pancreatic Neoplasms - enzymology | Lysosomes - enzymology | Melanoma - enzymology | Neoplasms - enzymology | Male | Cathepsin D - metabolism | Disease Progression | Ovarian Neoplasms - enzymology | Breast Neoplasms - enzymology | Enzyme Precursors - metabolism | Biomarkers, Tumor - metabolism | Prostatic Neoplasms - enzymology | Female | Endosomes - enzymology | Head and Neck Neoplasms - enzymology | Neoplasms - pathology
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6. BRAF V600E mutation-specific antibody: A review
by Ritterhouse, Lauren L and Barletta, Justine A
Seminars in diagnostic pathology, ISSN 0740-2570, 09/2015, Volume 32, Issue 5, pp. 400 - 408
Immunohistochemistry | BRAF V600E | Colorectal carcinoma | Melanoma | Thyroid carcinoma | Pathology | Life Sciences & Biomedicine | Medical Laboratory Technology | Science & Technology | Antibody Specificity | Predictive Value of Tests | Thyroid Neoplasms - enzymology | Colorectal Neoplasms - genetics | Humans | Antibodies | Melanoma - enzymology | Molecular Diagnostic Techniques | Skin Neoplasms - enzymology | DNA Mutational Analysis | Melanoma - genetics | Carcinoma - enzymology | Carcinoma - pathology | Skin Neoplasms - pathology | Colorectal Neoplasms - enzymology | Genetic Predisposition to Disease | Melanoma - pathology | Thyroid Neoplasms - genetics | Phenotype | Proto-Oncogene Proteins B-raf - genetics | Skin Neoplasms - genetics | Carcinoma - genetics | Biomarkers, Tumor - genetics | Mutation | Colorectal Neoplasms - pathology | Thyroid Neoplasms - pathology
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7. Full Text Somatic POLE exonuclease domain mutations are early events in sporadic endometrial and colorectal carcinogenesis, determining driver mutational landscape, clonal neoantigen burden and immune response
by Temko, Daniel and van Gool, Inge C and Rayner, Emily and Glaire, Mark and Makino, Seiko and Brown, Matthew and Chegwidden, Laura and Palles, Claire and Depreeuw, Jeroen and Beggs, Anew and Stathopoulou, Chaido and Mason, John and Baker, Ann-Marie and Williams, Marc and Cerundolo, Vincenzo and Rei, Margarida and Taylor, Jenny C and Schuh, Anna and Ahmed, Ahmed and Amant, Frédéric and Lambrechts, Diether and Smit, Vincent T. H. B. M and Bosse, Tjalling and Graham, Trevor A and Church, David N and Tomlinson, Ian
The Journal of pathology, ISSN 0022-3417, 2018, Volume 245, Issue 3, pp. 283 - 296
endometrial cancer | mutation | colorectal cancer | POLE | precursor lesion | polymerase proofreading | Pathology | Oncology | Life Sciences & Biomedicine | Science & Technology | Genomic Instability | Adenocarcinoma - pathology | Poly-ADP-Ribose Binding Proteins - metabolism | Colorectal Neoplasms - genetics | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Databases, Genetic | Tumor Microenvironment | Male | DNA Polymerase II - metabolism | Endometrial Neoplasms - immunology | Neoplasm Grading | Endometrial Neoplasms - genetics | Cell Transformation, Neoplastic - genetics | Antigens, Neoplasm - metabolism | CD8-Positive T-Lymphocytes - metabolism | Female | Lymphocytes, Tumor-Infiltrating - metabolism | Adenocarcinoma - genetics | DNA Polymerase II - genetics | Antigens, Neoplasm - genetics | Colorectal Neoplasms - enzymology | Genetic Predisposition to Disease | Endometrial Neoplasms - enzymology | Antigens, Neoplasm - immunology | Adenocarcinoma - immunology | Adenocarcinoma - enzymology | Poly-ADP-Ribose Binding Proteins - genetics | Gene Expression Profiling - methods | Cell Transformation, Neoplastic - metabolism | Whole Genome Sequencing | Cell Transformation, Neoplastic - immunology | Phenotype | Colorectal Neoplasms - immunology | Endometrial Neoplasms - pathology | Mutation | CD8-Positive T-Lymphocytes - immunology | Cell Transformation, Neoplastic - pathology | Colorectal Neoplasms - pathology | Neoplasm Staging | Lymphocytes, Tumor-Infiltrating - immunology | Genetic aspects | Immune response | Carcinogenesis | Tumor antigens | Prognosis | Stability | Initiators | CD8 antigen | p53 Protein | Colorectal carcinoma | Lymphocytes T | Genomes | Molecular chains | Gene sequencing | Genomic instability | Carcinogens | Exonuclease | Precursors | Tumorigenesis | Lesions | Endometrium | Cancer | Tumors | Immune system | Index Medicus | Original Papers | Original Paper
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8. Full Text Human tumor antigens Tn and sialyl Tn arise from mutations in Cosmc
by Ju, Tongzhong and Lanneau, Grainger S and Gautam, Tripti and Wang, Yingchun and Xia, Baoyun and Stowell, Sean R and Willard, Margaret T and Wang, Wenyi and Xia, Jonathan Y and Zuna, Rosemary E and Laszik, Zoltan and Benbrook, Doris M and Hanigan, Marie H and Cummings, Richard D
Cancer research (Chicago, Ill.), ISSN 0008-5472, 03/2008, Volume 68, Issue 6, pp. 1636 - 1646
Biological and medical sciences | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Tumors | Galactosyltransferases - deficiency | Colorectal Neoplasms - enzymology | Uterine Cervical Neoplasms - enzymology | Jurkat Cells | Colorectal Neoplasms - genetics | Humans | Molecular Chaperones - genetics | Melanoma - enzymology | Neoplasms - enzymology | Uterine Cervical Neoplasms - immunology | Galactosyltransferases - metabolism | Uterine Cervical Neoplasms - genetics | Colorectal Neoplasms - immunology | Transfection | Antigens, Tumor-Associated, Carbohydrate - genetics | Neoplasms - genetics | Melanoma - genetics | Melanoma - immunology | Neoplasms - immunology | Cell Line, Tumor | Female | Molecular Chaperones - immunology | Antigens, Tumor-Associated, Carbohydrate - biosynthesis | Index Medicus
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9. Full Text Repression of the Long Noncoding RNA-LET by Histone Deacetylase 3 Contributes to Hypoxia-Mediated Metastasis
by Yang, Fu and Huo, Xi-song and Yuan, Sheng-xian and Zhang, Ling and Zhou, Wei-ping and Wang, Fang and Sun, Shu-han
Molecular cell, ISSN 1097-2765, 03/2013, Volume 49, Issue 6, pp. 1083 - 1096
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Neoplasm Transplantation | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Molecular Sequence Data | Male | Carcinoma, Hepatocellular - secondary | Cell Hypoxia | Lung Neoplasms - secondary | Base Sequence | Carcinoma, Hepatocellular - genetics | Female | Liver Neoplasms - pathology | Acetylation | Liver Neoplasms - enzymology | Lung Neoplasms - genetics | Gene Expression | Lung Neoplasms - enzymology | Liver Neoplasms - genetics | Down-Regulation | RNA, Long Noncoding - genetics | Carcinoma, Hepatocellular - enzymology | Nuclear Factor 90 Proteins - metabolism | Animals | Mice, Nude | Cell Line, Tumor | Mice | Protein Processing, Post-Translational | Histone Deacetylases - physiology | Histones - metabolism | Nuclear Factor 90 Proteins - genetics | RNA, Long Noncoding - metabolism | Cell Movement | Medical colleges | Lung cancer | Colorectal cancer | Medical genetics | Development and progression | Antisense RNA | Metastasis | Health aspects | Index Medicus
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