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International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2010, Volume 78, Issue 1, pp. 127 - 135
Purpose To examine the risk of subsequent primary malignancies (SPMs) in women diagnosed with endometrial cancer. Methods and Materials The National Cancer... 
Radiology | Hematology, Oncology and Palliative Medicine | Radiation-induced malignancies | HNPCC | Endometrial cancer | Second primary malignancies | SURGERY | LYNCH-SYNDROME | NONPOLYPOSIS COLORECTAL-CANCER | 2ND PRIMARY CANCERS | RISK | CERVICAL-CANCER | RADIATION-THERAPY | UTERINE | ONCOLOGY | OVARIAN | CARCINOMA | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | United States - epidemiology | Colonic Neoplasms - genetics | Follow-Up Studies | Humans | Middle Aged | Bone Neoplasms - epidemiology | Pharyngeal Neoplasms - etiology | Esophageal Neoplasms - epidemiology | Incidence | Vaginal Neoplasms - genetics | Young Adult | Neoplasms, Radiation-Induced - genetics | Endometrial Neoplasms - genetics | Lung Neoplasms - etiology | Aged, 80 and over | Intestine, Small - radiation effects | Bone Neoplasms - genetics | Neoplasms, Second Primary - genetics | Mouth Neoplasms - genetics | SEER Program | Risk Assessment | Vaginal Neoplasms - etiology | Mouth Neoplasms - etiology | Neoplasms, Second Primary - epidemiology | Mouth Neoplasms - epidemiology | Pharyngeal Neoplasms - genetics | Vaginal Neoplasms - epidemiology | Adolescent | Pharyngeal Neoplasms - epidemiology | Endometrial Neoplasms - radiotherapy | Esophageal Neoplasms - etiology | Age Factors | Neoplasms, Radiation-Induced - etiology | Urinary Bladder Neoplasms - genetics | Adult | Female | Intestinal Neoplasms - genetics | Urinary Bladder Neoplasms - epidemiology | Colonic Neoplasms - etiology | Lung Neoplasms - genetics | Urinary Bladder Neoplasms - etiology | Colonic Neoplasms - epidemiology | Intestinal Neoplasms - etiology | Intestinal Neoplasms - epidemiology | Bone Neoplasms - etiology | Neoplasms, Second Primary - etiology | Lung Neoplasms - epidemiology | Esophageal Neoplasms - genetics | Aged | Neoplasms, Radiation-Induced - epidemiology | Genetic aspects | Research | Oncology, Experimental | Cancer | Index Medicus | LARGE INTESTINE | GASTROINTESTINAL TRACT | ORAL CAVITY | ESOPHAGUS | DIGESTIVE SYSTEM | LUNGS | MEDICINE | PHARYNX | THERAPY | RADIOLOGY AND NUCLEAR MEDICINE | BLADDER | RADIOTHERAPY | RADIOLOGY | SMALL INTESTINE | NEOPLASMS | UTERUS | INTESTINES | NUCLEAR MEDICINE | FEMALE GENITALS | ORGANS | URINARY TRACT | DISEASES | RESPIRATORY SYSTEM | BRACHYTHERAPY | BODY
Journal Article
BMC Genomics, ISSN 1471-2164, 04/2006, Volume 7, Issue 1, pp. 90 - 90
Background: Post-translational modification of histones resulting in chromatin remodelling plays a key role in the regulation of gene expression. Here we... 
BREAST-CANCER | CBP | METHYLATION | INHIBITION | BOOTSTRAP | ACETYLATION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | PATTERNS | MUTATIONS | REPRODUCIBILITY | PROGRESSION | Neoplasms - metabolism | Protein Methyltransferases | Pancreatic Neoplasms - metabolism | Colorectal Neoplasms - genetics | Histone Acetyltransferases - biosynthesis | Humans | Lung Neoplasms - metabolism | Protein Processing, Post-Translational - genetics | DNA, Complementary - genetics | Gene Expression Regulation, Neoplastic | Histone Acetyltransferases - genetics | Male | Histone-Lysine N-Methyltransferase - biosynthesis | Breast Neoplasms - metabolism | Ovarian Neoplasms - genetics | Polymorphism, Single-Stranded Conformational | Neoplasms - genetics | Cell Transformation, Neoplastic - genetics | Polymerase Chain Reaction | Female | Ovarian Neoplasms - metabolism | Neoplasm Proteins - genetics | Colorectal Neoplasms - metabolism | Lung Neoplasms - genetics | Histone-Lysine N-Methyltransferase - genetics | Histone Deacetylases - genetics | Neoplasm Proteins - biosynthesis | Linear Models | Pancreatic Neoplasms - genetics | Gene Expression Regulation, Enzymologic | Breast Neoplasms - genetics | Carcinoma - genetics | Carcinoma - metabolism | DNA, Neoplasm - genetics | Histones - metabolism | Histone Code - genetics | Cluster Analysis
Journal Article
by Jiang, Xia and Finucane, Hilary K and Schumacher, Fredrick R and Schmit, Stephanie L and Tyrer, Jonathan P and Han, Younghun and Michailidou, Kyriaki and Lesseur, Corina and Kuchenbaecker, Karoline B and Dennis, Joe and Conti, David V and Casey, Graham and Gaudet, Mia M and Huyghe, Jeroen R and Albanes, Demetrius and Aldrich, Melinda C and Andrew, Angeline S and Andrulis, Irene L and Anton-Culver, Hoda and Antoniou, Antonis C and Antonenkova, Natalia N and Arnold, Susanne M and Aronson, Kristan J and Arun, Banu K and Bandera, Elisa V and Barkardottir, Rosa B and Barnes, Daniel R and Batra, Jyotsna and Beckmann, Matthias W and Benitez, Javier and Benlloch, Sara and Berchuck, Andrew and Berndt, Sonja I and Bickeböller, Heike and Bien, Stephanie A and Blomqvist, Carl and Boccia, Stefania and Bogdanova, Natalia V and Bojesen, Stig E and Bolla, Manjeet K and Brauch, Hiltrud and Brenner, Hermann and Brenton, James D and Brook, Mark N and Brunet, Joan and Brunnström, Hans and Buchanan, Daniel D and Burwinkel, Barbara and Butzow, Ralf and Cadoni, Gabriella and Caldés, Trinidad and Caligo, Maria A and Campbell, Ian and Campbell, Peter T and Cancel-Tassin, Géraldine and Cannon-Albright, Lisa and Campa, Daniele and Caporaso, Neil and Carvalho, André L and Chan, Andrew T and Chang-Claude, Jenny and Chanock, Stephen J and Chen, Chu and Christiani, David C and Claes, Kathleen B. M and Claessens, Frank and Clements, Judith and Collée, J. Margriet and Correa, Marcia Cruz and Couch, Fergus J and Cox, Angela and Cunningham, Julie M and Cybulski, Cezary and Czene, Kamila and Daly, Mary B and deFazio, Anna and Devilee, Peter and Diez, Orland and Gago-Dominguez, Manuela and Donovan, Jenny L and Dörk, Thilo and Duell, Eric J and Dunning, Alison M and Dwek, Miriam and Eccles, Diana M and Edlund, Christopher K and Edwards, Digna R Velez and Ellberg, Carolina and Evans, D. Gareth and Fasching, Peter A and Ferris, Robert L and Liloglou, Triantafillos and Figueiredo, Jane C and Fletcher, Olivia and Fortner, Renée T and Fostira, Florentia and Franceschi, Silvia and Friedman, Eitan and Gallinger, Steven J and Ganz, Patricia A and ... and Institutionen för kliniska vetenskaper, Avdelningen för obstetrik och gynekologi and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Institute of Clinical Sciences, Department of Obstetrics and Gynecology and Sahlgrenska Academy
Nature communications, ISSN 2041-1723, 2019, Volume 10, Issue 1, pp. 431 - 23
Quantifying the genetic correlation between cancers can provide important insights into the mechanisms driving cancer etiology... 
BREAST-CANCER | LUNG-CANCER | RISK-FACTORS | PARTITIONING HERITABILITY | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY LOCI | GENETIC ARCHITECTURE | ANALYSES IDENTIFY | MENDELIAN RANDOMIZATION | CELL-TYPES | GENOME-WIDE ASSOCIATION | Lung Neoplasms - ethnology | Colorectal Neoplasms - genetics | Humans | Ovarian Neoplasms - pathology | Lung Neoplasms - pathology | Male | Prostatic Neoplasms - diagnosis | Case-Control Studies | Colorectal Neoplasms - diagnosis | Ovarian Neoplasms - ethnology | Inheritance Patterns | Ovarian Neoplasms - genetics | Mental Disorders - genetics | Prostatic Neoplasms - genetics | Smoking - physiopathology | Head and Neck Neoplasms - ethnology | Female | Neoplasm Proteins - genetics | Breast Neoplasms - ethnology | Lung Neoplasms - genetics | Prostatic Neoplasms - pathology | Genetic Predisposition to Disease | Genome-Wide Association Study | Colorectal Neoplasms - ethnology | Ovarian Neoplasms - diagnosis | European Continental Ancestry Group | Smoking - genetics | Prostatic Neoplasms - ethnology | Head and Neck Neoplasms - pathology | Mental Disorders - physiopathology | Smoking - ethnology | Phenotype | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Head and Neck Neoplasms - diagnosis | Head and Neck Neoplasms - genetics | Breast Neoplasms - diagnosis | Mental Disorders - ethnology | Polymorphism, Single Nucleotide | Colorectal Neoplasms - pathology | Lung Neoplasms - diagnosis | Enrichment | Correlation | Statistical analysis | Ovarian carcinoma | Mental disorders | Lung cancer | Colorectal carcinoma | Genomes | Breast cancer | Regulatory sequences | Ovarian cancer | Etiology | Breast | Heritability | Neck | Solid tumors | Prostate cancer | Prostate | Cancer | Smoking | Andrew R.] Univ Bristol | 3400 Civ Ctr | risk-factors | England | Miranda] Univ Bristol | Clalit Natl Canc Control Ctr | Kenneth] Mem Sloan Kettering Canc Ctr | Kinghorn Canc Ctr | randomization | Pring | Div Populat Hlth Hlth Serv Res & Primary Care | Seattle | Upper Maudlin St | Stanford | Sch Womens & Childrens Hlth | Offit | Duarte | Ulrike | Susan J.] Garvan Inst Med Res | Sydney | Moreno | Plaseska-Karanfilska | Victor] Univ Barcelona | Warwick Med Sch | Dept | Lab Med Program | Wilbert H. M.] Radboud Univ Nijmegen | Elizabeth J.] Univ Pretoria | Anna Marie] Univ Hlth Network | Peters | Nielsen | Ness | 18 High St | lung-cancer | Lindstrom | 1275 York | Kenneth] Univ Warwick | Kari] Decode Genet | Blegdamsvej 9 | Harvey A.] Yale Sch Publ Hlth | Neal | Liene] Latvian Biomed Res & Study Ctr | Kirsten B.] Roswell Pk Canc Inst | Science & Technology - Other Topics | partitioning heritability | Dept Genet | Dept Res | Billrothstr11 | Bristol BS2 | Israel | Dept Obstet & Gynecol | Geert Grooteplein Zuid | Dept Canc Biol & Genet | Res Ctr Genet Engn & Biotechnol Georgi | Nussbaum | Iceland | WA 98195 USA | Haartmaninkatu 8 | Paolo] INT | Robert L.] Univ Calif San Francisco | NSW 2010 | Buffalo | 384 Victoria St | Rosenstein | cell-types | CT 06510 USA | Med Ctr | van Rensburg | Gad | Dept Urol | Angela] Salzburg Univ | Dept Chron Dis Epidemiol | Finn Cilius] Copenhagen Univ Hosp | Clin Genet Serv | Dijana] Macedonian Acad Sci & Arts | Nikitina-Zake | 200 Elizabeth St | Susan L.] Beckman Res Inst City Hope | Dept Genet & Genom Sci | Canc Ctr Cluster Salzburg | Muir | IS-101 Reykjavik | Risch | Div Hlth Sci | Sch Med | Canc Genet & Prevent Program | Wei] Vanderbilt Univ | New York | susceptibility loci | genetic architecture | 60 Coll St | Anna Marie] Univ Toronto | Avon | IBELL | Roobol | Dept Populat Sci | NL-3015 CN Rotterdam | Lower Maudlin St | 1275 York Ave | Div Epidemiol | Radice | Fdn IRCCS | Neuenheimer Feld 280 | breast-cancer | 1600 Div St | Wytemaweg 80 | Sturlugata 8 | Latvia | Helsinki Univ Hosp | Coventry CV4 7AL | W Midlands | Catalan Inst Oncol | Unit Mol Bases Genet Risk & Genet Testing | Leon | Lisa F.] Univ Washington | ON M5S | Skopje 1000 | Sch Publ Hlth | Dept Oncol | Susan J.] Univ NSW Sydney | 7 Michal St | Bristol Dent Sch | Cambridge CB1 8RN | NSW | New Haven | Raskin | Moysich | Ratsupites Str 1 | Ctr Genom Med | TLRC H | Toronto | Germany | David E.] Univ Cambridge | Dept Radiat Oncol | Dept Med | Elm & Carlton St | Addenbrookes Hosp | A-5020 | Stefansson | Div Epigen & Canc Risk Factors | Katherine L.] Univ Penn | Abramson Canc Ctr | Via Giacomo | South | Bristol BS1 2LY | Rennert | Spain | Rigshosp | Mulligan | Obstetrics, Gynecology and Reproductive Medicine | Perelman Sch Med | Sara] Univ Washington | Blvd Krste Petkov Misirkov | 1500 E Duarte | genome-wide association | 1 Kings Coll Circle | Dept Gastroenterol | 1425 Madison Ave | Fac Med | mendelian | ZA-0007 Arcadia | Hedy S.] Technion Fac Med | Barry S.] Icahn Sch Med Mt Sinai | Angela] German Ctr Lung Res DZL | Nathanson | Dept Lab Med & Pathobiol | Clin Genet Res Lab | Nevanlinna | Heli] Univ Helsinki | Amanda I | Private Bag X323 | Ramus | ON M5G 2C4 | DK-2100 | 97239 USA | Newcomb | Macedonia | IL-34362 Haifa | PLUS | Div Canc Prevent & Control | San | Janet L | D-69120 Heidelberg | Barcelona 08908 | Monique J.] Erasmus Univ | CA 91010 | Kenneth] Univ Manchester | LV-1067 Riga | Neuhausen | Dept Mol Biol | fremov | NIHR Bristol Biomed Res Ctr Nutr Theme | Hedy S.] Carmel Hosp | analyses identify | FIN | Vanderbilt Ingram Canc Ctr | Oxford Rd | Phipps | Zheng | Angela] DKFZ German Canc Res Ctr | Reproduktionsmedicin och gynekologi
Journal Article
Scientific reports, ISSN 2045-2322, 2017, Volume 7, Issue 1, pp. 15500 - 10
Journal Article
Cell stem cell, ISSN 1934-5909, 2010, Volume 6, Issue 6, pp. 603 - 615
Recent evidence suggests that a subpopulation of cancer cells, cancer stem cells (CSCs), is responsible for tumor growth in colorectal cancer. However,... 
STEMCELL | CELLCYCLE | BREAST-CANCER | INITIATING CELLS | DIPEPTIDYL-PEPTIDASE-IV | CARCINOMA CELLS | EXTRACELLULAR-MATRIX | ACUTE MYELOID-LEUKEMIA | E-CADHERIN | IDENTIFICATION | TUMOR-GROWTH | HUMAN PANCREATIC-CANCER | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Neoplasm Transplantation | RNA, Small Interfering - genetics | Prognosis | Follow-Up Studies | Apoptosis - drug effects | Neoplastic Stem Cells - drug effects | Colorectal Neoplasms - genetics | Humans | Apoptosis - genetics | Gene Expression Profiling | Colorectal Neoplasms - diagnosis | Organoplatinum Compounds - pharmacology | Neoplastic Stem Cells - metabolism | Cell Transformation, Neoplastic - genetics | Colorectal Neoplasms - drug therapy | Liver Neoplasms - physiopathology | Neoplastic Stem Cells - pathology | Tumor Burden - genetics | Tumor Cells, Cultured | Liver Neoplasms - secondary | Colorectal Neoplasms - metabolism | Carcinoma - secondary | Carcinoma - drug therapy | Liver Neoplasms - genetics | Dipeptidyl Peptidase 4 - biosynthesis | Liver Neoplasms - drug therapy | Carcinoma - diagnosis | Dipeptidyl Peptidase 4 - genetics | Mice, SCID | Carcinoma - physiopathology | Disease Progression | Colorectal Neoplasms - physiopathology | Drug Resistance, Neoplasm - genetics | Animals | Liver Neoplasms - diagnosis | Tumor Burden - drug effects | Liver Neoplasms - metabolism | Carcinoma - genetics | Biomarkers, Tumor - genetics | Fluorouracil - pharmacology | Mice | Carcinoma - metabolism | Colorectal Neoplasms - pathology | Neoplasm Invasiveness - genetics | Cell Migration Assays | Biomarkers, Tumor - biosynthesis
Journal Article
Gastroenterology, ISSN 0016-5085, 2009, Volume 137, Issue 6, pp. 1976 - 1985.e10
Background & Aims MUTYH -associated polyposis (MAP) is characterized by a lifetime risk of colorectal cancer of up to 100%. However, no systematic evaluation... 
Gastroenterology and Hepatology | BASE-EXCISION-REPAIR | URINARY-TRACT CANCER | APC GENE MUTATION | MUIR-TORRE-SYNDROME | NONPOLYPOSIS COLORECTAL-CANCER | DUODENAL ADENOMATOSIS | FAMILIAL ADENOMATOUS POLYPOSIS | MYH-ASSOCIATED POLYPOSIS | LYNCH SYNDROME | GASTROENTEROLOGY & HEPATOLOGY | MSH2 MUTATION CARRIERS | Gastrointestinal Neoplasms - genetics | Humans | Middle Aged | Adenomatous Polyposis Coli - epidemiology | Ovarian Neoplasms - pathology | Male | Adenomatous Polyposis Coli - pathology | Incidence | Ovarian Neoplasms - genetics | Young Adult | Gastrointestinal Neoplasms - pathology | Gastrointestinal Neoplasms - epidemiology | Urinary Bladder Neoplasms - genetics | Urinary Bladder Neoplasms - pathology | Adult | Female | Retrospective Studies | Endoscopy | Adenomatous Polyposis Coli - genetics | Child | Urinary Bladder Neoplasms - epidemiology | Breast Neoplasms - epidemiology | Skin Neoplasms - pathology | Genetic Predisposition to Disease | Sebaceous Gland Neoplasms - epidemiology | Risk Assessment | Risk Factors | Sebaceous Gland Neoplasms - genetics | DNA Glycosylases - genetics | Kaplan-Meier Estimate | Europe - epidemiology | Skin Neoplasms - epidemiology | Ovarian Neoplasms - epidemiology | Phenotype | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Sebaceous Gland Neoplasms - pathology | Skin Neoplasms - genetics | Adolescent | Age of Onset | Aged | Medical colleges | Animal pigments | Genetic disorders | Oncology, Experimental | Colorectal cancer | Research | Cancer | Tumors | Medical informatics
Journal Article
Nature (London), ISSN 1476-4687, 2014, Volume 513, Issue 7518, pp. 382 - 387
Journal Article
Oncogene, ISSN 0950-9232, 04/2008, Volume 27, Issue 18, pp. 2635 - 2647
TMPRSS4 is a novel type II transmembrane serine protease found at the cell surface that is highly expressed in pancreatic, colon and gastric cancer tissues.... 
Serine protease | Metastasis | E-cadherin | EMT | Invasion | TMPRSS4 | PROSTATE | MATRIPTASE | SURFACE PROTEOLYTIC-ENZYMES | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | serine protease | CELL BIOLOGY | BREAST-CANCER CELLS | MATRIX METALLOPROTEINASES | invasion | PLASMINOGEN-ACTIVATOR | ONCOLOGY | metastasis | GENETICS & HEREDITY | TRANSMEMBRANE SERINE PROTEASES | EXPRESSION | RNA, Small Interfering - genetics | Cadherins - metabolism | Humans | Neoplasm Proteins - antagonists & inhibitors | Cell Movement - genetics | Neoplasm Metastasis | Serine Endopeptidases - genetics | Liver Neoplasms - pathology | Cadherins - genetics | Liver Neoplasms - enzymology | Liver Neoplasms - secondary | Neoplasm Proteins - genetics | Gene Expression Regulation, Neoplastic - genetics | Lung Neoplasms - enzymology | Liver Neoplasms - genetics | Serine Endopeptidases - biosynthesis | Membrane Proteins - genetics | Epithelial Cells - pathology | Lung Neoplasms - therapy | Gastrointestinal Neoplasms - enzymology | Gastrointestinal Neoplasms - therapy | Cell Adhesion | Cell Movement - drug effects | Membrane Proteins - biosynthesis | Membrane Proteins - antagonists & inhibitors | Gene Expression Regulation, Enzymologic - genetics | Mice, Nude | Cell Communication - drug effects | Epithelial Cells - enzymology | Cell Line, Tumor | Biomarkers, Tumor - genetics | Cadherins - antagonists & inhibitors | Mice | RNA-Binding Proteins - metabolism | Gene Expression Regulation, Enzymologic - drug effects | Neoplasm Transplantation | RNA-Binding Proteins - genetics | Gastrointestinal Neoplasms - genetics | Lung Neoplasms - pathology | Liver Neoplasms - therapy | Gastrointestinal Neoplasms - pathology | Gene Expression Regulation, Neoplastic - drug effects | Lung Neoplasms - genetics | Neoplasm Invasiveness | Neoplasm Proteins - biosynthesis | Cell Communication - genetics | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Animals | Biomarkers, Tumor - biosynthesis | Care and treatment | Control | Proteases | Cancer cells | Physiological aspects | Genetic aspects | Research | Risk factors | Oncology | Genetics | Cellular biology | Pancreatic cancer | Colorectal cancer
Journal Article