X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (46573) 46573
Book Chapter (57) 57
Newsletter (44) 44
Newspaper Article (40) 40
Publication (17) 17
Book / eBook (15) 15
Dissertation (9) 9
Magazine Article (8) 8
Web Resource (2) 2
Book Review (1) 1
Conference Proceeding (1) 1
Streaming Video (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (42728) 42728
oncology (20355) 20355
female (20196) 20196
colorectal cancer (19457) 19457
male (18913) 18913
middle aged (14954) 14954
cancer (14269) 14269
colorectal-cancer (13358) 13358
aged (13094) 13094
animals (13065) 13065
colorectal neoplasms - pathology (12390) 12390
colorectal neoplasms - metabolism (11755) 11755
cell line, tumor (9810) 9810
adult (9554) 9554
colorectal neoplasms - genetics (8931) 8931
expression (8546) 8546
mice (8018) 8018
prognosis (7733) 7733
tumors (7631) 7631
metastasis (7136) 7136
apoptosis (6826) 6826
gene expression regulation, neoplastic (6253) 6253
immunohistochemistry (6216) 6216
research (5990) 5990
aged, 80 and over (5918) 5918
gene expression (5458) 5458
cell biology (5115) 5115
analysis (4891) 4891
proteins (4814) 4814
colorectal neoplasms - drug therapy (4711) 4711
colon cancer (4700) 4700
biochemistry & molecular biology (4600) 4600
chemotherapy (4414) 4414
genetic aspects (4401) 4401
colon-cancer (4330) 4330
carcinoma (4313) 4313
breast-cancer (4235) 4235
signal transduction (4141) 4141
cell proliferation (4117) 4117
risk factors (4098) 4098
health aspects (4092) 4092
mutation (4027) 4027
colorectal carcinoma (3927) 3927
biomarkers, tumor - metabolism (3911) 3911
care and treatment (3688) 3688
gastroenterology & hepatology (3657) 3657
neoplasm staging (3605) 3605
surgery (3564) 3564
development and progression (3544) 3544
cells (3463) 3463
colonic neoplasms - pathology (3442) 3442
colon (3380) 3380
pathology (3337) 3337
survival (3324) 3324
research article (3247) 3247
colonic neoplasms - metabolism (3225) 3225
medicine & public health (3026) 3026
mice, nude (2989) 2989
medicine (2919) 2919
growth (2903) 2903
tumor cells, cultured (2792) 2792
apoptosis - drug effects (2719) 2719
adenocarcinoma - metabolism (2699) 2699
multidisciplinary sciences (2674) 2674
genes (2638) 2638
antineoplastic agents - pharmacology (2635) 2635
pharmacology & pharmacy (2594) 2594
studies (2587) 2587
risk (2575) 2575
kinases (2529) 2529
adenocarcinoma - pathology (2498) 2498
activation (2497) 2497
cancer therapies (2463) 2463
biomarkers (2456) 2456
medical prognosis (2440) 2440
breast cancer (2435) 2435
cell proliferation - drug effects (2389) 2389
proliferation (2385) 2385
dna methylation (2376) 2376
hct116 cells (2374) 2374
neoplasm metastasis (2364) 2364
case-control studies (2323) 2323
disease progression (2320) 2320
down-regulation (2319) 2319
medicine, research & experimental (2317) 2317
cell cycle (2270) 2270
treatment outcome (2269) 2269
reverse transcriptase polymerase chain reaction (2262) 2262
neoplasm invasiveness (2242) 2242
gene (2230) 2230
physiological aspects (2202) 2202
cancer research (2198) 2198
biomarkers, tumor - genetics (2183) 2183
blotting, western (2176) 2176
carcinogenesis (2161) 2161
gene-expression (2152) 2152
angiogenesis (2145) 2145
up-regulation (2104) 2104
metastases (2083) 2083
science (2076) 2076
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (46169) 46169
Chinese (445) 445
Japanese (267) 267
French (81) 81
Russian (51) 51
German (43) 43
Polish (41) 41
Spanish (36) 36
Hungarian (24) 24
Korean (22) 22
Italian (19) 19
Portuguese (9) 9
Czech (8) 8
Danish (6) 6
Bulgarian (4) 4
Dutch (3) 3
Ukrainian (3) 3
Finnish (2) 2
Romanian (2) 2
Slovak (2) 2
Arabic (1) 1
Hebrew (1) 1
Norwegian (1) 1
Serbian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


BMC Genomics, ISSN 1471-2164, 04/2006, Volume 7, Issue 1, pp. 90 - 90
Background: Post-translational modification of histones resulting in chromatin remodelling plays a key role in the regulation of gene expression. Here we... 
BREAST-CANCER | CBP | METHYLATION | INHIBITION | BOOTSTRAP | ACETYLATION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | PATTERNS | MUTATIONS | REPRODUCIBILITY | PROGRESSION | Neoplasms - metabolism | Protein Methyltransferases | Pancreatic Neoplasms - metabolism | Colorectal Neoplasms - genetics | Histone Acetyltransferases - biosynthesis | Humans | Lung Neoplasms - metabolism | Protein Processing, Post-Translational - genetics | DNA, Complementary - genetics | Gene Expression Regulation, Neoplastic | Histone Acetyltransferases - genetics | Male | Histone-Lysine N-Methyltransferase - biosynthesis | Breast Neoplasms - metabolism | Ovarian Neoplasms - genetics | Polymorphism, Single-Stranded Conformational | Neoplasms - genetics | Cell Transformation, Neoplastic - genetics | Polymerase Chain Reaction | Female | Ovarian Neoplasms - metabolism | Neoplasm Proteins - genetics | Colorectal Neoplasms - metabolism | Lung Neoplasms - genetics | Histone-Lysine N-Methyltransferase - genetics | Histone Deacetylases - genetics | Neoplasm Proteins - biosynthesis | Linear Models | Pancreatic Neoplasms - genetics | Gene Expression Regulation, Enzymologic | Breast Neoplasms - genetics | Carcinoma - genetics | Carcinoma - metabolism | DNA, Neoplasm - genetics | Histones - metabolism | Histone Code - genetics | Cluster Analysis
Journal Article
The American journal of surgical pathology, ISSN 0147-5185, 2017, Volume 41, Issue 3, pp. 326 - 333
Mismatch repair (MMR)-deficient endometrial carcinomas (ECs) bearing Lynch syndrome (LS)-associated germline mutations or sporadic MLH1 promoter... 
PD-L1 | mismatch repair | endometrial carcinoma | MLH1 hypermethylation | immunotherapy | Lynch syndrome | SURGERY | MICROSATELLITE INSTABILITY | INFILTRATING LYMPHOCYTES | IMMUNOSCORE | PATHOLOGY | LUNG-CANCER | PROGNOSTIC-FACTOR | IMMUNE-SYSTEM | MICROENVIRONMENT | COLORECTAL-CANCER | BLOCKADE | Immunohistochemistry | Neoplastic Syndromes, Hereditary - pathology | Prognosis | Follow-Up Studies | Endometrial Neoplasms - mortality | Colorectal Neoplasms - genetics | Colorectal Neoplasms, Hereditary Nonpolyposis - pathology | Humans | Middle Aged | Brain Neoplasms - pathology | Endometrial Neoplasms - metabolism | Gene Expression Regulation, Neoplastic | Neoplastic Syndromes, Hereditary - metabolism | Brain Neoplasms - metabolism | Neoplastic Syndromes, Hereditary - mortality | Colorectal Neoplasms, Hereditary Nonpolyposis - mortality | DNA Methylation | Endometrial Neoplasms - genetics | DNA Mismatch Repair | Biomarkers, Tumor - metabolism | Female | Neoplastic Syndromes, Hereditary - genetics | Brain Neoplasms - mortality | Colorectal Neoplasms - metabolism | Colorectal Neoplasms - mortality | Promoter Regions, Genetic | Colorectal Neoplasms, Hereditary Nonpolyposis - genetics | Brain Neoplasms - genetics | Colorectal Neoplasms, Hereditary Nonpolyposis - metabolism | B7-H1 Antigen - metabolism | MutL Protein Homolog 1 - genetics | Endometrial Neoplasms - pathology | Aged | Biomarkers, Tumor - genetics | Colorectal Neoplasms - pathology
Journal Article
Metabolism, ISSN 0026-0495, 2015, Volume 64, Issue 2, pp. 182 - 189
Journal Article
Annals of the Royal College of Surgeons of England, ISSN 0035-8843, 03/2017, Volume 99, Issue 3, pp. 193 - 197
INTRODUCTION Neuroendocrine tumours (NETs) are a heterogeneous group of tumours with a highly variable presentation and prognosis. Management decisions are... 
Ki-67 | Pathology | Neuroendocrine tumours | Diagnostic techniques and procedures | General surgery | SURVIVAL | SURGERY | PROGNOSTIC-FACTORS | NEOPLASMS | ENDOCRINE TUMORS | RGETNE | DISEASE | REGISTRY | Colorectal Neoplasms - surgery | Digestive System Neoplasms - metabolism | Pancreatic Neoplasms - metabolism | Prognosis | Humans | Lung Neoplasms - metabolism | Middle Aged | Stomach Neoplasms - metabolism | Ki-67 Antigen - metabolism | Lung Neoplasms - pathology | Male | Stomach Neoplasms - pathology | Neoplasm Grading | Digestive System Neoplasms - pathology | Adult | Female | Liver Neoplasms - pathology | Retrospective Studies | Biopsy, Large-Core Needle | Colorectal Neoplasms - metabolism | Ileal Neoplasms - pathology | Neuroendocrine Tumors - pathology | Ileal Neoplasms - surgery | Neuroendocrine Tumors - metabolism | Pancreatic Neoplasms - pathology | Pancreatic Neoplasms - surgery | Ileal Neoplasms - metabolism | Liver Neoplasms - surgery | Biopsy, Fine-Needle | Digestive System Neoplasms - surgery | Liver Neoplasms - metabolism | Lung Neoplasms - surgery | Neuroendocrine Tumors - surgery | Aged | Colorectal Neoplasms - pathology | Stomach Neoplasms - surgery | Cohort Studies | Ultrasonic imaging | Laboratories | Medical prognosis | Cell cycle | Hormones | Metastasis | Endoscopy | Epidemiology | Cancer therapies | Tumors | Oncology
Journal Article
by Ma, YC and Chen, HB and Ma, HY and Yao, ZH and Hu, JW and Ma, J and Zhang, XQ and Chen, GW and Liu, YC
SAUDI MEDICAL JOURNAL, ISSN 0379-5284, 08/2019, Volume 40, Issue 8, pp. 755 - 765
Objectives: To analyze the heterogeneous functions of secreted protein acidic and rich in cysteine (SPARC) from different origins and in different tumor... 
SURVIVAL | LUNG-CANCER | PREDICTS | MEDICINE, GENERAL & INTERNAL | GASTRIC-CANCER | PANCREATIC-CANCER | MARKERS | SPARC EXPRESSION | GEMCITABINE | PROGRESSION | PACLITAXEL | Esophageal Squamous Cell Carcinoma - metabolism | Neoplasms - metabolism | Nasopharyngeal Neoplasms - metabolism | Nasopharyngeal Neoplasms - mortality | Pancreatic Neoplasms - metabolism | Prognosis | Lung Neoplasms - mortality | Humans | Lung Neoplasms - metabolism | Stomach Neoplasms - metabolism | Tumor Microenvironment | Biliary Tract Neoplasms - mortality | Lymphoma, Large B-Cell, Diffuse - metabolism | Breast Neoplasms - metabolism | Esophageal Neoplasms - metabolism | Biliary Tract Neoplasms - metabolism | Esophageal Neoplasms - mortality | Pancreatic Neoplasms - mortality | Colorectal Neoplasms - metabolism | Colorectal Neoplasms - mortality | Nasopharyngeal Carcinoma - mortality | Proportional Hazards Models | Neoplasms - mortality | Osteonectin - metabolism | Nasopharyngeal Carcinoma - metabolism | Survival Rate | Lymphoma, Large B-Cell, Diffuse - mortality | Disease-Free Survival | Esophageal Squamous Cell Carcinoma - mortality | Breast Neoplasms - mortality | Stomach Neoplasms - mortality | Medical research | Cysteine | Care and treatment | Analysis | Pancreatic cancer | Colorectal cancer | Medicine, Experimental | Development and progression | Cystine | Proteins | Angiogenesis | Medical prognosis | Bias | Fibroblasts | Lymphomas | Metastasis | Stomach cancer | Tumors | Cell adhesion & migration | Meta-analysis | Systematic Review | meta-analysis | SPARC | tumor microenvironment | prognosis | stroma
Journal Article
Cell stem cell, ISSN 1934-5909, 2010, Volume 6, Issue 6, pp. 603 - 615
Recent evidence suggests that a subpopulation of cancer cells, cancer stem cells (CSCs), is responsible for tumor growth in colorectal cancer. However,... 
STEMCELL | CELLCYCLE | BREAST-CANCER | INITIATING CELLS | DIPEPTIDYL-PEPTIDASE-IV | CARCINOMA CELLS | EXTRACELLULAR-MATRIX | ACUTE MYELOID-LEUKEMIA | E-CADHERIN | IDENTIFICATION | TUMOR-GROWTH | HUMAN PANCREATIC-CANCER | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Neoplasm Transplantation | RNA, Small Interfering - genetics | Prognosis | Follow-Up Studies | Apoptosis - drug effects | Neoplastic Stem Cells - drug effects | Colorectal Neoplasms - genetics | Humans | Apoptosis - genetics | Gene Expression Profiling | Colorectal Neoplasms - diagnosis | Organoplatinum Compounds - pharmacology | Neoplastic Stem Cells - metabolism | Cell Transformation, Neoplastic - genetics | Colorectal Neoplasms - drug therapy | Liver Neoplasms - physiopathology | Neoplastic Stem Cells - pathology | Tumor Burden - genetics | Tumor Cells, Cultured | Liver Neoplasms - secondary | Colorectal Neoplasms - metabolism | Carcinoma - secondary | Carcinoma - drug therapy | Liver Neoplasms - genetics | Dipeptidyl Peptidase 4 - biosynthesis | Liver Neoplasms - drug therapy | Carcinoma - diagnosis | Dipeptidyl Peptidase 4 - genetics | Mice, SCID | Carcinoma - physiopathology | Disease Progression | Colorectal Neoplasms - physiopathology | Drug Resistance, Neoplasm - genetics | Animals | Liver Neoplasms - diagnosis | Tumor Burden - drug effects | Liver Neoplasms - metabolism | Carcinoma - genetics | Biomarkers, Tumor - genetics | Fluorouracil - pharmacology | Mice | Carcinoma - metabolism | Colorectal Neoplasms - pathology | Neoplasm Invasiveness - genetics | Cell Migration Assays | Biomarkers, Tumor - biosynthesis
Journal Article
Cancer letters, ISSN 0304-3835, 2007, Volume 251, Issue 1, pp. 132 - 145
Abstract Betulinic acid (BA) is a widely available plant-derived triterpene with reported activity against cancer cells of neuroectodermal origin and... 
Hematology, Oncology and Palliative Medicine | Chemotherapy | Lung cancer | Betulinic acid | Colorectal cancer | Breast cancer | Prostate cancer | Cervical cancer | Apoptosis | ACTIVATION | colorectal cancer | INDUCED APOPTOSIS | breast cancer | apoptosis | TUMOR-CELLS | betulinic acid | IDENTIFICATION | cervical cancer | chemotherapy | CYTOTOXIC ACTIVITY | lung cancer | prostate cancer | ONCOLOGY | HUMAN-MELANOMA CELLS | SERINE-PROTEASE | INDUCED DEATH | INHIBITOR | DERIVATIVES | Neoplasms - metabolism | Lung Neoplasms - drug therapy | Prostatic Neoplasms - metabolism | Triterpenes - pharmacology | Apoptosis - drug effects | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Male | Uterine Cervical Neoplasms - pathology | Breast Neoplasms - metabolism | Dose-Response Relationship, Drug | Uterine Cervical Neoplasms - metabolism | Colorectal Neoplasms - drug therapy | Female | Colorectal Neoplasms - metabolism | Prostatic Neoplasms - drug therapy | Cell Survival - drug effects | Prostatic Neoplasms - pathology | Jurkat Cells | Cells, Cultured | Uterine Cervical Neoplasms - drug therapy | Breast Neoplasms - drug therapy | Blotting, Western | Neoplasms - drug therapy | Poly(ADP-ribose) Polymerases - metabolism | Breast Neoplasms - pathology | Cell Line, Tumor | Antineoplastic Agents, Phytogenic - pharmacology | Colorectal Neoplasms - pathology | Neoplasms - pathology | Cancer
Journal Article
Gastroenterology, ISSN 0016-5085, 2015, Volume 149, Issue 4, pp. 1017 - 1029.e3
Background & Aims Patients with bi-allelic germline mutations in mismatch repair (MMR) genes ( MLH1 , MSH2 , MSH6 , or PMS2 ) develop a rare but severe variant... 
Gastroenterology and Hepatology | Tumor | Colon Cancer | Predisposition | Functional Tests | SYSTEM | CELLS | BIALLELIC MUTATIONS | SOMATIC MUTATIONS | HEREDITARY | COLORECTAL-CANCER | PMS2 | MSH6 MUTATIONS | GASTROENTEROLOGY & HEPATOLOGY | GOLD STANDARD | NEUROFIBROMATOSIS TYPE-1 | MutL Protein Homolog 1 | Predictive Value of Tests | Colorectal Neoplasms - genetics | Colorectal Neoplasms, Hereditary Nonpolyposis - pathology | Humans | Drug Resistance, Neoplasm | Male | Neoplastic Syndromes, Hereditary - metabolism | Colorectal Neoplasms - diagnosis | Young Adult | DNA Mutational Analysis | Colorectal Neoplasms - drug therapy | Germ-Line Mutation | Mismatch Repair Endonuclease PMS2 | Neoplastic Syndromes, Hereditary - genetics | Caco-2 Cells | Lymphocytes - metabolism | Genetic Predisposition to Disease | Colorectal Neoplasms, Hereditary Nonpolyposis - drug therapy | Brain Neoplasms - diagnosis | HCT116 Cells | Brain Neoplasms - genetics | Neoplastic Syndromes, Hereditary - diagnosis | Heredity | MutS Homolog 2 Protein - genetics | Brain Neoplasms - drug therapy | Multiplex Polymerase Chain Reaction | Antineoplastic Agents, Alkylating - therapeutic use | Colorectal Neoplasms, Hereditary Nonpolyposis - metabolism | Phenotype | Adenosine Triphosphatases - genetics | Biomarkers, Tumor - genetics | Neoplastic Syndromes, Hereditary - drug therapy | Microsatellite Instability | Neoplastic Syndromes, Hereditary - pathology | Brain Neoplasms - pathology | DNA Repair Enzymes - genetics | Genetic Testing - methods | Brain Neoplasms - metabolism | Case-Control Studies | Transfection | Colorectal Neoplasms, Hereditary Nonpolyposis - diagnosis | Adult | Female | Nuclear Proteins - genetics | Colorectal Neoplasms - metabolism | Reproducibility of Results | Colorectal Neoplasms, Hereditary Nonpolyposis - genetics | DNA-Binding Proteins - genetics | Lymphocytes - drug effects | Adaptor Proteins, Signal Transducing - genetics | Colorectal Neoplasms - pathology | Methylation | Lymphomas | Diagnosis | Gene mutations | Lymphocytes | Leukemia | Colorectal cancer
Journal Article
PloS one, ISSN 1932-6203, 2017, Volume 12, Issue 6, p. e0179501
Innovative therapies for solid tumors are urgently needed. Recently, therapies that harness the host immune system to fight cancer cells have successfully... 
CD2 | THERAPY | IMMUNOTHERAPY | MULTIDISCIPLINARY SCIENCES | GENES | IMMUNOMODULATORY ACTION | MECHANISMS | MOLECULES | SGI-110 | Colonic Neoplasms - genetics | DNA Methylation - immunology | DNA, Neoplasm - metabolism | Humans | Antigens, Neoplasm - biosynthesis | Ovarian Neoplasms - pathology | Male | Colonic Neoplasms - metabolism | Testicular Neoplasms - pathology | Ovarian Neoplasms - genetics | Colonic Neoplasms - immunology | Female | Ovarian Neoplasms - metabolism | Caco-2 Cells | Antigens, Neoplasm - genetics | Testicular Neoplasms - genetics | Antigens, Neoplasm - immunology | Testicular Neoplasms - metabolism | Antigen Presentation - genetics | DNA Methylation - genetics | Testicular Neoplasms - immunology | Animals | Colonic Neoplasms - pathology | DNA, Neoplasm - immunology | Mice | DNA, Neoplasm - genetics | Ovarian Neoplasms - immunology | Colon cancer | Tumor antigens | Physiological aspects | Development and progression | Genetic aspects | Research | Methylation | Ovarian cancer | Therapy | Biotechnology | Animal models | Ovarian carcinoma | Medical innovations | CD58 antigen | Antigen processing | Genomes | Tissues | Cancer therapies | Immunotherapy | Surgery | Cell cycle | DNA methylation | Inhibition | Colon | Drug dosages | Deoxyribonucleic acid--DNA | Immune system | Antigen presentation | Antigens | Tumor cells | Melanoma | Tumor cell lines | Gene expression | Ribonucleic acid--RNA | Patients | Medicine | Inhibitors | Epigenetics | Solid tumors | Tumors | Cancer | RNA | Deoxyribonucleic acid | Ribonucleic acid | DNA
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 04/2012, Volume 287, Issue 16, pp. 12975 - 12984
The mitotic checkpoint gene CHFR (checkpoint with fork-head-associated (FHA) and RING finger domains) is silenced by promoter hypermethylation or mutated in... 
MICROTUBULE INHIBITORS | INSTABILITY | GENE | EPIGENETIC INACTIVATION | COLORECTAL-CANCER | DNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | POLY(ADP-RIBOSE) POLYMERASE-1 | CELL-CYCLE | BETA-CATENIN | EXPRESSION | Neoplasms - metabolism | Lung Neoplasms - drug therapy | Mouth Neoplasms - drug therapy | Humans | Lung Neoplasms - metabolism | Stomach Neoplasms - metabolism | Lung Neoplasms - pathology | Male | Mouth Neoplasms - metabolism | Stomach Neoplasms - pathology | Breast Neoplasms | Poly-ADP-Ribose Binding Proteins | Microtubules - drug effects | Genes, Tumor Suppressor - physiology | Neoplasms, Squamous Cell - drug therapy | Tumor Suppressor Proteins - genetics | Drug Design | HEK293 Cells | Female | Ubiquitination - physiology | Neoplasms, Squamous Cell - pathology | Carcinoma, Non-Small-Cell Lung - pathology | Tumor Suppressor Proteins - metabolism | Mice, Inbred C57BL | Carcinoma, Non-Small-Cell Lung - metabolism | Microtubules - physiology | Ubiquitin-Protein Ligases - metabolism | Cell Cycle Checkpoints - physiology | Stomach Neoplasms - drug therapy | Mice, Knockout | Neoplasms - drug therapy | Poly(ADP-ribose) Polymerases - metabolism | Animals | Mouth Neoplasms - pathology | Mice | Carcinoma, Non-Small-Cell Lung - drug therapy | HeLa Cells | Poly (ADP-Ribose) Polymerase-1 | Neoplasms - pathology | Ubiquitin-Protein Ligases - genetics | M Phase Cell Cycle Checkpoints - physiology | Neoplasms, Squamous Cell - metabolism | Molecular Bases of Disease | Cancer Therapy | E3 Ubiquitin Ligase | Checkpoint Control | Cell Cycle | PARP Inhibitor | Tumor Suppressor Gene | PARP-1 | CHFR
Journal Article