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1. Full Text Current Clinical and Preclinical Photosensitizers for Use in Photodynamic Therapy
by Detty, Michael R and Gibson, Scott L and Wagner, Stephen J
Journal of medicinal chemistry, ISSN 0022-2623, 07/2004, Volume 47, Issue 16, pp. 3897 - 3915
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Biological and medical sciences | Treatment. General aspects | Treatment with physical agents | Medical sciences | Photoradiation therapy and photosensitizing agent | Tumors | Cations - chemistry | Photosensitizing Agents - chemistry | Porphyrins - therapeutic use | Photosensitizing Agents - therapeutic use | Coloring Agents - pharmacology | Photochemotherapy - methods | Humans | Porphyrins - chemistry | Porphyrins - pharmacology | Macular Degeneration - drug therapy | Erythrocytes - drug effects | Neoplasms - drug therapy | Erythrocytes - microbiology | Photosensitizing Agents - pharmacology | Animals | Coloring Agents - therapeutic use | Drug Evaluation, Preclinical | Coloring Agents - chemistry | Index Medicus
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2. Full Text Enhancement of chemotherapeutic response of tumor cells by a heme oxygenase inhibitor, pegylated zinc protoporphyrin
by Fang, Jun and Sawa, Tomohiro and Akaike, Takaaki and Greish, Khaled and Maeda, Hiroshi
International journal of cancer, ISSN 0020-7136, 03/2004, Volume 109, Issue 1, pp. 1 - 8
heme oxygenase‐1 | zinc protoporphyrin | macromolecular therapeutics | tumor targeting/EPR effect | D‐amino acid oxidase | Macromolecular therapeutics | D-amino acid oxidase | Tumor targeting/EPR effect | Heme oxygenase-1 | Zinc protoporphyrin | Life Sciences & Biomedicine | Oncology | Science & Technology | Biological and medical sciences | Chemotherapy | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Oxidants - pharmacology | Body Weight | Reactive Oxygen Species - metabolism | Oxidative Stress | Coloring Agents - pharmacology | Annexin A5 - pharmacology | Humans | Male | Metalloporphyrins - pharmacology | Oxygen - metabolism | Dose-Response Relationship, Drug | Antineoplastic Agents - pharmacology | Heme Oxygenase (Decyclizing) - antagonists & inhibitors | Polyethylene Glycols - pharmacology | Oxidation-Reduction | Hydrogen Peroxide - pharmacology | Etoposide - pharmacology | Tetrazolium Salts - pharmacology | Cisplatin - pharmacology | Hydrogen Peroxide - metabolism | Mitomycin - pharmacology | Neoplasms - drug therapy | Proline - chemistry | Drug Synergism | Animals | Cell Line, Tumor | Mice | Thiazoles - pharmacology | Antineoplastic Agents, Phytogenic - pharmacology | Camptothecin - pharmacology | Doxorubicin - pharmacology | Apoptosis | Index Medicus
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3. Full Text Histone deacetylase inhibitor LAQ824 down-regulates Her-2 and sensitizes human breast cancer cells to trastuzumab, taxotere, gemcitabine, and epothilone B
by Lianne Fuino and Purva Bali and Sylvie Wittmann and Sreenivas Donapaty and Fei Guo and Hirohito Yamaguchi and Hong-Gang Wang and Peter Atadja and Kapil Bhalla
Molecular Cancer Therapeutics, ISSN 1535-7163, 10/2003, Volume 2, Issue 10, pp. 971 - 984
Life Sciences & Biomedicine | Oncology | Science & Technology | Chromatin - metabolism | Phosphorylation | Taxoids - pharmacology | Coloring Agents - pharmacology | Annexin A5 - pharmacology | Humans | Epothilones - pharmacology | Multienzyme Complexes - metabolism | Deoxycytidine - pharmacology | Proteasome Endopeptidase Complex | Dose-Response Relationship, Drug | Antibodies, Monoclonal, Humanized | Sepharose - pharmacology | Cysteine Endopeptidases - metabolism | Flow Cytometry | Cyclins - metabolism | Time Factors | Antimetabolites, Antineoplastic - pharmacology | Antineoplastic Agents - pharmacology | Hydroxamic Acids - pharmacology | Detergents - pharmacology | Receptor, ErbB-2 - biosynthesis | Cyclin-Dependent Kinase Inhibitor p21 | Antibodies, Monoclonal - pharmacology | Down-Regulation | Enzyme Inhibitors - pharmacology | Tetrazolium Salts - pharmacology | Reverse Transcriptase Polymerase Chain Reaction | Breast Neoplasms - drug therapy | Blotting, Western | Precipitin Tests | Blotting, Northern | Cell Line, Tumor | Histone Deacetylase Inhibitors | Thiazoles - pharmacology | Antineoplastic Agents, Phytogenic - pharmacology | Deoxycytidine - analogs & derivatives | Microscopy, Fluorescence | Trastuzumab | Apoptosis | Index Medicus
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4. Full Text Curcumin—From Molecule to Biological Function
by Esatbeyoglu, Tuba and Huebbe, Patricia and Ernst, Insa M. A and Chin, Dawn and Wagner, Anika E and Rimbach, Gerald
Angewandte Chemie (International ed.), ISSN 1433-7851, 05/2012, Volume 51, Issue 22, pp. 5308 - 5332
cancer | total synthesis | neuroprotection | gene expression | curcumin | Animals | Antioxidants - chemistry | Curcumin - chemistry | Humans | Curcumin - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Antineoplastic Agents - pharmacology | Antioxidants - pharmacology | Antineoplastic Agents - chemistry | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Spices | Gene expression | Index Medicus | Antioxidants | Coloring | Color | Organisms | Foods | Biological
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5. Full Text cAMP Response Element-Mediated Gene Transcription Is Upregulated by Chronic Antidepressant Treatment
by Thome, J and Sakai, N and Shin, K.-H and Steffen, C and Zhang, Y.-J and Impey, S and Storm, D and Duman, R. S
The Journal of neuroscience, ISSN 0270-6474, 06/2000, Volume 20, Issue 11, pp. 4030 - 4036
β-galactosidase | CRE enhancer | Phosphorylation | Tranylcypromine | Desipramine | Fluoxetine | Gene transcription | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Brain Chemistry - drug effects | Transcription, Genetic - drug effects | Coloring Agents | Desipramine - pharmacology | Tranylcypromine - pharmacology | Lac Operon - drug effects | Antidepressive Agents - pharmacology | Haloperidol - pharmacology | Fluoxetine - pharmacology | Monoamine Oxidase Inhibitors - pharmacology | Cyclic AMP Response Element-Binding Protein - biosynthesis | Dopamine Uptake Inhibitors - pharmacology | Mice, Transgenic | Antidepressive Agents, Second-Generation - pharmacology | Up-Regulation - drug effects | Cocaine - pharmacology | Cyclic AMP Response Element-Binding Protein - genetics | Animals | beta-Galactosidase - biosynthesis | Antidepressive Agents, Tricyclic - pharmacology | Mice | Antipsychotic Agents - pharmacology | Transcription, Genetic - genetics | beta-Galactosidase - genetics | Index Medicus | ARTICLE | gene transcription | fluoxetine | tranylcypromine | phosphorylation | desipramine
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6. Full Text Diketopyrrolopyrrole‐Porphyrin Conjugates with High Two‐Photon Absorption and Singlet Oxygen Generation for Two‐Photon Photodynamic Therapy
by Schmitt, Julie and Heitz, Valérie and Sour, Angélique and Bolze, Frédéric and Ftouni, Hussein and Nicoud, Jean‐Francois and Flamigni, Lucia and Ventura, Barbara
Angewandte Chemie (International ed.), ISSN 1433-7851, 01/2015, Volume 54, Issue 1, pp. 169 - 173
dyes/pigments | two‐photon absorption | diketopyrroles | singlet oxygen | photodynamic therapy | porphyrins | Dyes/pigments | Two-photon absorption | Diketopyrroles | Photodynamic therapy | Singlet oxygen | Porphyrins | Cell Survival - drug effects | Photosensitizing Agents - chemistry | Coloring Agents - pharmacology | Humans | Porphyrins - chemistry | Photons | Porphyrins - pharmacology | Photochemotherapy | Photosensitizing Agents - pharmacology | Pyrroles - pharmacology | Singlet Oxygen - chemistry | HEK293 Cells | Pyrroles - chemistry | HeLa Cells | Coloring Agents - chemistry | Active oxygen | Cancer | Oxygen | Index Medicus | Conjugates | Biotechnology | Dyes | Absorption | Excitation | Cross sections
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7. Full Text Screening of anti-cancer agent using zebrafish: Comparison with the MTT assay
by Li, Yigen and Huang, Wenjin and Huang, Shenyuan and Du, Jiulin and Huang, Cheng
Biochemical and biophysical research communications, ISSN 0006-291X, 05/2012, Volume 422, Issue 1, pp. 85 - 90
Zebrafish | Anti-cancer drug | MTT assay | Apoptosis | p53 | P53 | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Emodin - pharmacology | Gene Expression - drug effects | Apoptosis - drug effects | Humans | Transcriptional Activation | Dimethyl Sulfoxide - pharmacology | Naphthoquinones - pharmacology | Tetrazolium Salts - chemistry | Lignans - pharmacology | Tumor Suppressor Protein p53 - genetics | Animals | Biphenyl Compounds - pharmacology | Antineoplastic Agents - isolation & purification | Rotenone - pharmacology | Cell Line, Tumor | Thiazoles - chemistry | Antineoplastic Agents - pharmacology | Camptothecin - pharmacology | Coloring Agents - chemistry | Drug Screening Assays, Antitumor | Antimitotic agents | Usage | Care and treatment | Analysis | Medicine, Chinese | Diagnosis | Antineoplastic agents | Tumor proteins | Cancer | Index Medicus
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8. Full Text Anti-SARS coronavirus 3C-like protease effects of Isatis indigotica root and plant-derived phenolic compounds
by Lin, Cheng-Wen and Tsai, Fuu-Jen and Tsai, Chang-Hai and Lai, Chien-Chen and Wan, Lei and Ho, Tin-Yun and Hsieh, Chang-Chi and Chao, Pei-Dawn Lee
Antiviral research, ISSN 0166-3542, 2005, Volume 68, Issue 1, pp. 36 - 42
3C-like protease | Isatis indigotica root | SARS-coronavirus | Phenolic compounds | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Science & Technology | Virology | Antiviral agents | Pharmacognosy. Homeopathy. Health food | General pharmacology | Pharmacology. Drug treatments | Biological and medical sciences | Medical sciences | Antibiotics. Antiinfectious agents. Antiparasitic agents | Coloring Agents - pharmacology | Indigo Carmine | Plant Extracts - pharmacology | Glucosinolates - chemistry | Viral Proteins - metabolism | Enzyme Inhibitors - chemistry | Indoles - pharmacology | Viral Proteins - drug effects | Phenols - pharmacology | Cysteine Endopeptidases | Endopeptidases - metabolism | Chlorocebus aethiops | Emodin - pharmacology | Enzyme Inhibitors - pharmacology | Emodin - chemistry | Vero Cells - metabolism | Animals | Glucosinolates - pharmacology | Anthraquinones | Plant Roots - chemistry | Hesperidin - chemistry | Hesperidin - pharmacology | Endopeptidases - drug effects | Indoles - chemistry | Coloring Agents - chemistry | Isatis - chemistry | Proteins | Medical colleges | Polypeptides | Proteases | Analysis | Medical genetics | Phytosterols | Glycosides | Index Medicus
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