Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (6929) 6929
Patent (2337) 2337
Publication (648) 648
Book Chapter (250) 250
Book / eBook (218) 218
Book Review (143) 143
Newsletter (72) 72
Conference Proceeding (68) 68
Web Resource (33) 33
Dissertation (15) 15
Magazine Article (15) 15
Paper (8) 8
Newspaper Article (6) 6
Streaming Video (3) 3
Reference (2) 2
Journal / eJournal (1) 1
Technical Report (1) 1
Trade Publication Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
combinatorial chemistry (3446) 3446
chemistry (3217) 3217
combinatorial chemistry techniques (2686) 2686
index medicus (2530) 2530
metallurgy (2339) 2339
libraries, e.g. chemical libraries, in silicolibraries (2337) 2337
combinatorial chemistry techniques - methods (2120) 2120
biochemistry (1928) 1928
microbiology (1716) 1716
enzymology (1640) 1640
wine (1630) 1630
beer (1627) 1627
mutation or genetic engineering (1627) 1627
spirits (1627) 1627
vinegar (1627) 1627
physics (1618) 1618
humans (1563) 1563
chemistry, multidisciplinary (1557) 1557
organic chemistry (1528) 1528
testing (1377) 1377
measuring (1362) 1362
investigating or analysing materials by determining theirchemical or physical properties (1333) 1333
molecular structure (1303) 1303
performing operations (1248) 1248
transporting (1248) 1248
compositions or test papers therefor (1239) 1239
condition-responsive control in microbiological orenzymological processes (1239) 1239
measuring or testing processes involving enzymes, nucleicacids or microorganisms (1239) 1239
processes of preparing such compositions (1239) 1239
chemistry, medicinal (1204) 1204
physical or chemical processes or apparatus in general (1159) 1159
chemical or physical processes, e.g. catalysis or colloidchemistry (1118) 1118
their relevant apparatus (1118) 1118
culture media (1074) 1074
chemistry, applied (1071) 1071
compositions thereof (1068) 1068
microorganisms or enzymes (1068) 1068
propagating, preserving or maintaining microorganisms (1068) 1068
peptides (1065) 1065
biochemistry & molecular biology (1059) 1059
animals (1004) 1004
drug design (938) 938
biochemical research methods (912) 912
chemistry, organic (908) 908
combinatorial analysis (835) 835
drug discovery (833) 833
ligands (801) 801
pharmacology & pharmacy (765) 765
peptide library (732) 732
catalysis (708) 708
apparatus therefor (707) 707
general methods of organic chemistry (681) 681
nucleic acids (598) 598
research (593) 593
electricity (578) 578
libraries (571) 571
structure-activity relationship (567) 567
models, molecular (559) 559
proteins (558) 558
nanotechnology (545) 545
sugars (544) 544
nucleosides (542) 542
nucleotides (539) 539
analysis (530) 530
general tagging of cross-sectional technologies spanning over several sections of the ipc (529) 529
general tagging of new technological developments (529) 529
technical subjects covered by former uspc cross-reference art collections [xracs] and digests (529) 529
derivatives thereof (526) 526
stereoisomerism (523) 523
biotechnology & applied microbiology (505) 505
combinatorial libraries (496) 496
algorithms (485) 485
manufacture or treatment of nanostructures (481) 481
measurement or analysis of nanostructures (481) 481
specific uses or applications of nanostructures (481) 481
inhibitors (459) 459
human necessities (453) 453
discovery (449) 449
article (448) 448
design (442) 442
chemical or physical laboratory apparatus for general use (427) 427
chemistry, analytical (422) 422
derivatives (422) 422
amino acid sequence (415) 415
methods (403) 403
technical subjects covered by former uspc (401) 401
solid-phase synthesis (400) 400
models, chemical (398) 398
protein binding (389) 389
identification (384) 384
multidisciplinary sciences (359) 359
computer simulation (354) 354
molecular sequence data (350) 350
counting (341) 341
calculating (339) 339
computing (339) 339
peptides - chemistry (335) 335
binding sites (334) 334
biology (334) 334
technical subjects covered by former us classification (317) 317
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (96) 96
Online Resources - Online (43) 43
UofT at Mississauga - Stacks (37) 37
Mathematical Sciences - Stacks (31) 31
Collection Dvlpm't (Acquisitions) - Vendor file (27) 27
Engineering & Comp. Sci. - Stacks (20) 20
Collection Dvlpm't (Acquisitions) - Closed Orders (15) 15
UofT at Scarborough - Stacks (12) 12
UTL at Downsview - May be requested (11) 11
Chemistry (A D Allen) - Stacks (9) 9
Gerstein Science - Circulation Desk (2) 2
Mathematical Sciences - Missing (2) 2
Physics - Stacks (2) 2
Trinity College (John W Graham) - Stacks (2) 2
Engineering & Comp. Sci. - Missing (1) 1
Gerstein Science - Online (1) 1
Trinity College (John W Graham) - Storage (1) 1
UofT at Mississauga - May be requested in 6-10 wks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (9664) 9664
French (1007) 1007
German (285) 285
Chinese (104) 104
Japanese (60) 60
Korean (34) 34
Spanish (33) 33
Portuguese (26) 26
Russian (10) 10
Czech (7) 7
Danish (7) 7
Finnish (5) 5
Arabic (4) 4
Hungarian (4) 4
Swedish (4) 4
Polish (3) 3
Dutch (1) 1
Hebrew (1) 1
Norwegian (1) 1
Ukrainian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Chemoinformatics
: theory, practice, & products
by Bunin, Barry A
2007, ISBN 9781402050008, xi, 295
Unique combination of theory and product overviewsColour Screenshots of major products from virtually all the major chemoinformatics suppliersWeb-based... 
Cheminformatics | Mathematics | Data processing | Chemistry | Medicinal Chemistry | Molecular Medicine | Bioinformatics | Computer Applications in Chemistry | Organic Chemistry
Book
Details down arrow
2. Chemogenomics
: methods and applications
by Jacoby, Edgar
2009, Methods in molecular biology, ISBN 9781607612735, Volume 575., x, 320
Pharmacogenetics | Combinatorial Chemistry Techniques | Genomics | methods | Drug Design | Chemogenomics | Chémogénomique | Life Sciences | Biochemistry, general | Analytical Chemistry | Combinatorial Libraries
Book
Details down arrow
3. Searching for molecular solutions
: empirical discovery and its future
by Dunn, Ian S
2010, ISBN 0470146826, xix, 458
A comprehensive look at empirical approaches to molecular discovery, their relationships with rational design, and the future of both Empirical methods of... 
Drugs | Design | Biochemistry | Research
Book
Details down arrow
4. Reverse chemical genetics
: methods and protocols
by Koga, Hisashi
2009, Methods in molecular biology, ISBN 9781607612322, Volume 577., xi, 272
Molecular Biology | methods | Biochemical genetics | Human Genetics | Gene Function | Biomedicine
Book
Details down arrow
5. Chemoinformatics and computational chemical biology
by Bajorath, Jürgen
2011, Methods in molecular biology, ISBN 1607618389, Volume 672., x, 588
Cheminformatics | Combinatorial Chemistry Techniques | methods | Chemistry, Pharmaceutical
Book
Details down arrow
6. Full Text Facile removal of stabilizer-ligands from supported gold nanoparticles
by Lopez-Sanchez, Jose A and Dimitratos, Nikolaos and Hammond, Ceri and Brett, Gemma L and Kesavan, Lokesh and White, Saul and Miedziak, Peter and Tiruvalam, Ramchandra and Jenkins, Robert L and Carley, Albert F and Knight, David and Kiely, Christopher J and Hutchings, Graham J
Nature Chemistry, ISSN 1755-4330, 05/2011, Volume 3, Issue 7, pp. 551 - 556
Metal nanoparticles that comprise a few hundred to several thousand atoms have many applications in areas such as photonics, sensing, medicine and catalysis.... 
ALCOHOLS | HYDROGEN | SELECTIVE OXIDATION | CALCINATION TEMPERATURE | CLUSTERS | GLYCEROL | TEMPERATURE CO OXIDATION | COLLOIDS | CATALYTIC-ACTIVITY | CHEMISTRY, MULTIDISCIPLINARY | Combinatorial Chemistry Techniques - methods | Gold - chemistry | Particle Size | Colloids - chemistry | Metal Nanoparticles - chemistry | Surface Properties | Ligands | Palladium - chemistry
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text The growing applications of click chemistry
by Moses, John E and Moorhouse, Adam D
Chemical Society reviews, ISSN 0306-0012, 08/2007, Volume 36, Issue 8, pp. 1249 - 1262
Click chemistry, the subject of this tutorial review, is a modular synthetic approach towards the assembly of new molecular entities. This powerful strategy... 
Combinatorial Chemistry Techniques - methods | Cross-Linking Reagents | Copper - chemistry | Triazoles - chemistry | Drug Design | Alkynes - chemistry | Catalysis | Azides - chemistry
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Chemoinformatics approaches to virtual screening
by Varnek, Alexandre and Tropsha, Alex
2008, ISBN 9780854041442, xvi, 338
Chemoinformatics is broadly a scientific discipline encompassing the design, creation, organization, management, retrieval, analysis, dissemination,... 
Cheminformatics | Chemistry | Data processing
Book
Details down arrow
9. An extracellular matrix microarray for probing cellular differentiation
by Flaim, Christopher J and Chien, Shu and Bhatia, Sangeeta N
Nature Methods, ISSN 1548-7091, 02/2005, Volume 2, Issue 2, pp. 119 - 125
We present an extracellular matrix (ECM) microarray platform for the culture of patterned cells atop combinatorial matrix mixtures. This platform enables the... 
IN-VITRO | HEPATOCYTES | PROTEIN | INTEGRIN | EMBRYONIC STEM-CELLS | GROWTH | BIOCHEMICAL RESEARCH METHODS | GENE-EXPRESSION | ADHESION MOLECULES | MAMMALIAN-CELLS | CULTURE | Microfluidic Analytical Techniques - methods | Stem Cells - cytology | Robotics - instrumentation | Cell Culture Techniques - methods | Equipment Design | Hepatocytes - cytology | Combinatorial Chemistry Techniques - instrumentation | Cell Differentiation - physiology | Hepatocytes - drug effects | Combinatorial Chemistry Techniques - methods | Microarray Analysis - methods | Cell Line | Extracellular Matrix Proteins - chemistry | Cell Culture Techniques - instrumentation | Microarray Analysis - instrumentation | Microfluidic Analytical Techniques - instrumentation | Extracellular Matrix Proteins - pharmacology | Rats | Molecular Probe Techniques - instrumentation | Animals | Cell Differentiation - drug effects | Stem Cells - drug effects | Robotics - methods | Mice | Equipment Failure Analysis
Journal Article
Details down arrow
10. Full Text Diversity-oriented synthesis as a tool for the discovery of novel biologically active small molecules
by Spring, David R and Galloway, Warren R.J.D and Isidro-Llobet, Albert
Nature Communications, ISSN 2041-1723, 09/2010, Volume 1, Issue 6, pp. 1 - 13
Biologically active molecules can be identified through the screening of small-molecule libraries. Deficiencies in current compound collections are evidenced... 
COMPOUND LIBRARIES | SYNTHESIS STRATEGY | ORGANIC-CHEMISTRY | MEDIUM RINGS | NATURAL-PRODUCTS | MULTIDISCIPLINARY SCIENCES | DRUG DISCOVERY | BIOLOGY | CHEMICAL SPACE | STRUCTURAL DIVERSITY | SKELETAL DIVERSITY | Combinatorial Chemistry Techniques - methods | Drug Discovery - methods | Molecular Structure | Small Molecule Libraries
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Knockout rats generated by embryo microinjection of TALENs
by Tesson, Laurent and Usal, Claire and Meq́noret, Seq́verine and Leung, Elo and Niles, Brett J and Remy, Seq́verine and Santiago, Yolanda and Vincent, Anna I and Meng, Xiangdong and Zhang, Lei and Gregory, Philip D and Anegon, Ignacio and Cost, Gregory J
Nature Biotechnology, ISSN 1087-0156, 08/2011, Volume 29, Issue 8, pp. 695 - 696
BIOTECHNOLOGY & APPLIED MICROBIOLOGY | STEM-CELLS | DNA-BINDING SPECIFICITY | Combinatorial Chemistry Techniques - methods | Transcription Factors - metabolism | Mutagenesis, Site-Directed - methods | Genetic Engineering | Transcription Factors - genetics | Humans | Genetically modified mice | Physiological aspects | Nucleases | Genetic engineering | Research
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text Combinatorial strategies in fluorescent probe development
by Vendrell, Marc and Zhai, Duanting and Er, Jun Cheng and Chang, Young-Tae
Chemical Reviews, ISSN 0009-2665, 08/2012, Volume 112, Issue 8, pp. 4391 - 4420
HIGH-THROUGHPUT SCREENS | PATTERN-RECOGNITION | SOLID-PHASE SYNTHESIS | IN-VITRO SELECTION | HIGH-AFFINITY | HYDROGEN-PEROXIDE | LANTHANIDE-BINDING TAGS | QUANTITATIVE-ANALYSIS | PARALLEL SYNTHESIS | CHEMISTRY, MULTIDISCIPLINARY | DIFFERENTIAL RECEPTORS | Combinatorial Chemistry Techniques - methods | Fluorescent Dyes - chemical synthesis | Fluorescent Dyes - chemistry | Animals | Humans | Drug Design | Spectrometry, Fluorescence | Carbohydrates | Emission spectra | Optical properties | Analysis | Substitution reactions | Amides | Spectra | Chemical properties | Ring formation (Chemistry) | Research | Nucleic acids
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
13. Full Text Strategies for Innovation in Multicomponent Reaction Design
by Ganem, Bruce
Accounts of Chemical Research, ISSN 0001-4842, 03/2009, Volume 42, Issue 3, pp. 463 - 472
By generating structural complexity in a single step from three or more reactants, multicomponent reactions (MCRs) make it possible to synthesize target... 
KETONES | HETEROCYCLES | ONE-POT | CHEMISTRY | OXAZOLES | CHEMISTRY, MULTIDISCIPLINARY | DISCOVERY | INDOLES | CHLORIDE | Combinatorial Chemistry Techniques - methods | Models, Chemical | Logic | Chemistry - methods | Ammonia | Chemical reaction, Rate of | Analysis | Nitriles | Cyanides | Chemical properties | Aldehydes | Synthetic Methodology | Multicomponent Reactions | Diversity-Oriented Synthesis
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
14. Full Text Dynamic combinatorial chemistry: a tool to facilitate the identification of inhibitors for protein targets
by Mondal, Milon and Hirsch, Anna K H
Chemical Society Reviews, ISSN 1460-4744, 04/2015, Volume 44, Issue 8, pp. 2455 - 88
Dynamic combinatorial chemistry (DCC) has emerged as a powerful strategy to identify ligands for biological targets given that it enables the target to direct... 
CYCLIN-DEPENDENT KINASES | OXYGENASE INHIBITORS | HYDROLYTIC ACTIVITY | GLUTATHIONE ANALOGS | MS-BINDING ASSAYS | COVALENT CHEMISTRY | MOLECULAR RECOGNITION | DRUG DISCOVERY | ALPHA-CHYMOTRYPSIN | MASS-SPECTROMETRY LEADS | CHEMISTRY, MULTIDISCIPLINARY | Combinatorial Chemistry Techniques - methods | Proteins - metabolism | Humans | Drug Discovery - methods | Ligands | Proteins - chemistry | Proteins - antagonists & inhibitors
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
15. Full Text Combinatorial chemistry in drug discovery
by Liu, Ruiwu and Li, Xiaocen and Lam, Kit S
Current Opinion in Chemical Biology, ISSN 1367-5931, 06/2017, Volume 38, pp. 117 - 126
Several combinatorial methods have been developed to create focused or diverse chemical libraries with a wide range of linear or macrocyclic chemical... 
BICYCLIC PEPTIDES | 1 INHIBITORS | ENCODED CHEMICAL LIBRARIES | IN-VITRO | DESIGN | BIOPHYSICS | MACROCYCLIC PEPTIDES