Blood, ISSN 0006-4971, 07/2010, Volume 116, Issue 1, pp. 7 - 15
Common variable immunodeficiency is a rare immune deficiency, characterized by low levels of serum immunoglobulin G, A, and/or M with loss of antibody...
PRIMARY IMMUNODEFICIENCY DISEASES | GRANULOMATOUS-DISEASE | MEMORY B-CELLS | NODULAR REGENERATIVE HYPERPLASIA | PRIMARY HYPOGAMMAGLOBULINEMIA | INTRAVENOUS IMMUNOGLOBULIN | ANTIBODY-DEFICIENCY | IGA DEFICIENCY | OF-THE-LITERATURE | HEMATOLOGY | INTERNET-BASED PATIENT | Common Variable Immunodeficiency - immunology | Humans | Common Variable Immunodeficiency - blood | Hematologic Diseases - immunology | Hematologic Diseases - therapy | Neoplasms - therapy | Bacterial Infections - therapy | Neoplasms - blood | Immunoglobulins, Intravenous - therapeutic use | Bacterial Infections - immunology | Common Variable Immunodeficiency - therapy | Hematologic Diseases - blood | Neoplasms - immunology | Survival Analysis | Bacterial Infections - blood | How I Treat | Immunobiology
PRIMARY IMMUNODEFICIENCY DISEASES | GRANULOMATOUS-DISEASE | MEMORY B-CELLS | NODULAR REGENERATIVE HYPERPLASIA | PRIMARY HYPOGAMMAGLOBULINEMIA | INTRAVENOUS IMMUNOGLOBULIN | ANTIBODY-DEFICIENCY | IGA DEFICIENCY | OF-THE-LITERATURE | HEMATOLOGY | INTERNET-BASED PATIENT | Common Variable Immunodeficiency - immunology | Humans | Common Variable Immunodeficiency - blood | Hematologic Diseases - immunology | Hematologic Diseases - therapy | Neoplasms - therapy | Bacterial Infections - therapy | Neoplasms - blood | Immunoglobulins, Intravenous - therapeutic use | Bacterial Infections - immunology | Common Variable Immunodeficiency - therapy | Hematologic Diseases - blood | Neoplasms - immunology | Survival Analysis | Bacterial Infections - blood | How I Treat | Immunobiology
Journal Article
Annals of the New York Academy of Sciences, ISSN 0077-8923, 12/2011, Volume 1246, Issue 1, pp. 41 - 49
Common variable immunodeficiency (CVID) is considered to be a collection of genetic immune defects with complex inheritance patterns. While the main phenotype...
genome‐wide association studies | IgA deficiency | single nucleotide polymorphism | recessive genes | common variable immunodeficiency | hypogammaglobulinemia | copy number variations | Genome-wide association studies | Common variable immunodeficiency | Copy number variations | Hypogammaglobulinemia | Single nucleotide polymorphism | Recessive genes | MULTIDISCIPLINARY SCIENCES | RECEPTOR | T-CELL | SELECTIVE IGA DEFICIENCY | CELL-CYCLE PROGRESSION | B-CELLS | BAFF-R | IMMUNODEFICIENCY DISORDERS | TACI | GENETICS & HEREDITY | CHROMOSOMAL RADIOSENSITIVITY | MUTATIONS | genome-wide association studies | Common Variable Immunodeficiency - immunology | Genome-Wide Association Study | Humans | Common Variable Immunodeficiency - genetics | Antigens, CD19 - genetics | Tetraspanin 28 - immunology | DNA Copy Number Variations | Receptors, Interleukin-4 - genetics | Polymorphism, Single Nucleotide | Tetraspanin 28 - genetics | Genome, Human | Antigens, CD19 - immunology | Genetic Linkage | Immunoglobulin A | Genomics | Analysis | Genes | Genomes | Defects
genome‐wide association studies | IgA deficiency | single nucleotide polymorphism | recessive genes | common variable immunodeficiency | hypogammaglobulinemia | copy number variations | Genome-wide association studies | Common variable immunodeficiency | Copy number variations | Hypogammaglobulinemia | Single nucleotide polymorphism | Recessive genes | MULTIDISCIPLINARY SCIENCES | RECEPTOR | T-CELL | SELECTIVE IGA DEFICIENCY | CELL-CYCLE PROGRESSION | B-CELLS | BAFF-R | IMMUNODEFICIENCY DISORDERS | TACI | GENETICS & HEREDITY | CHROMOSOMAL RADIOSENSITIVITY | MUTATIONS | genome-wide association studies | Common Variable Immunodeficiency - immunology | Genome-Wide Association Study | Humans | Common Variable Immunodeficiency - genetics | Antigens, CD19 - genetics | Tetraspanin 28 - immunology | DNA Copy Number Variations | Receptors, Interleukin-4 - genetics | Polymorphism, Single Nucleotide | Tetraspanin 28 - genetics | Genome, Human | Antigens, CD19 - immunology | Genetic Linkage | Immunoglobulin A | Genomics | Analysis | Genes | Genomes | Defects
Journal Article
Blood, ISSN 0006-4971, 02/2012, Volume 119, Issue 7, pp. 1650 - 1657
The demographics, immunologic parameters, medical complications, and mortality statistics from 473 subjects with common variable immune deficiency followed...
MEMORY B-CELLS | IMMUNODEFICIENCY DISORDERS | TACI | HYPOGAMMAGLOBULINEMIA | INTRAVENOUS IMMUNOGLOBULIN | DISEASE | ANTIBODY-DEFICIENCY | IGA DEFICIENCY | MUTATIONS | HEMATOLOGY | CANCER | Morbidity - trends | Humans | Middle Aged | Male | Mortality - trends | Young Adult | Common Variable Immunodeficiency - mortality | Time Factors | Common Variable Immunodeficiency - epidemiology | Adolescent | Aged, 80 and over | Adult | Female | Aged | Child | Cohort Studies | Clinical Trials and Observations | Immunobiology
MEMORY B-CELLS | IMMUNODEFICIENCY DISORDERS | TACI | HYPOGAMMAGLOBULINEMIA | INTRAVENOUS IMMUNOGLOBULIN | DISEASE | ANTIBODY-DEFICIENCY | IGA DEFICIENCY | MUTATIONS | HEMATOLOGY | CANCER | Morbidity - trends | Humans | Middle Aged | Male | Mortality - trends | Young Adult | Common Variable Immunodeficiency - mortality | Time Factors | Common Variable Immunodeficiency - epidemiology | Adolescent | Aged, 80 and over | Adult | Female | Aged | Child | Cohort Studies | Clinical Trials and Observations | Immunobiology
Journal Article
Immunological Reviews, ISSN 0105-2896, 01/2019, Volume 287, Issue 1, pp. 145 - 161
Summary Starting about 60 years ago, a number of reports appeared that outlined the severe clinical course of a few adult subjects with profound...
B‐cell development | immune globulin | antibody | genetics | autoimmunity | common variable immune deficiency | genetic defects | enteropathy | noninfectious complications | plasma cells | immune dysregulation | B-cell development | DENDRITIC CELLS | INNATE LYMPHOID-CELLS | IMMUNOLOGY | INTERSTITIAL LUNG-DISEASE | GRANULOMATOUS-DISEASE | NODULAR REGENERATIVE HYPERPLASIA | MEMORY B-CELLS | PRIMARY HYPOGAMMAGLOBULINEMIA | IMMUNODEFICIENCY DISORDERS | CHROMOSOMAL RADIOSENSITIVITY | T-CELLS | Immunoglobulin M | Immunoglobulins | Immunoglobulin G | Inflammation | Lymphoid tissue | Immunoglobulin A | Lymph nodes | Defects | Respiratory tract | Life span | Globulins | Lymphocytes B | Plasma cells | Genetics | Respiratory tract diseases
B‐cell development | immune globulin | antibody | genetics | autoimmunity | common variable immune deficiency | genetic defects | enteropathy | noninfectious complications | plasma cells | immune dysregulation | B-cell development | DENDRITIC CELLS | INNATE LYMPHOID-CELLS | IMMUNOLOGY | INTERSTITIAL LUNG-DISEASE | GRANULOMATOUS-DISEASE | NODULAR REGENERATIVE HYPERPLASIA | MEMORY B-CELLS | PRIMARY HYPOGAMMAGLOBULINEMIA | IMMUNODEFICIENCY DISORDERS | CHROMOSOMAL RADIOSENSITIVITY | T-CELLS | Immunoglobulin M | Immunoglobulins | Immunoglobulin G | Inflammation | Lymphoid tissue | Immunoglobulin A | Lymph nodes | Defects | Respiratory tract | Life span | Globulins | Lymphocytes B | Plasma cells | Genetics | Respiratory tract diseases
Journal Article
Chest, ISSN 0012-3692, 09/2019, Volume 156, Issue 3, pp. 579 - 593
Common variable immunodeficiency disorders refer to a relatively common primary immune deficiency group of diseases that present with infectious and...
liver disease | malignancy | common variable immune deficiency | granuloma | IVIG | asthma | sarcoidosis | hypogammaglobulinemia | lymphadenopathy | bronchiectasis | splenomegaly | nodular lymphoid hyperplasia | DIAGNOSIS | MANAGEMENT | HYPERPLASIA | RESPIRATORY SYSTEM | LUNG-DISEASE | LYMPHOID INTERSTITIAL PNEUMONITIS | ANTIBODY DEFICIENCY | IMMUNODEFICIENCY | CRITICAL CARE MEDICINE | Intravenous therapy | Immunological deficiency syndromes | Usage | Care and treatment | Diagnosis
liver disease | malignancy | common variable immune deficiency | granuloma | IVIG | asthma | sarcoidosis | hypogammaglobulinemia | lymphadenopathy | bronchiectasis | splenomegaly | nodular lymphoid hyperplasia | DIAGNOSIS | MANAGEMENT | HYPERPLASIA | RESPIRATORY SYSTEM | LUNG-DISEASE | LYMPHOID INTERSTITIAL PNEUMONITIS | ANTIBODY DEFICIENCY | IMMUNODEFICIENCY | CRITICAL CARE MEDICINE | Intravenous therapy | Immunological deficiency syndromes | Usage | Care and treatment | Diagnosis
Journal Article
Annals of Allergy, Asthma & Immunology, ISSN 1081-1206, 2016, Volume 118, Issue 1, pp. 122 - 122
Journal Article
Autoimmunity Reviews, ISSN 1568-9972, 2006, Volume 5, Issue 7, pp. 465 - 470
Common variable immunodeficiency (CVID) is a heterogeneous syndrome characterized by various degrees of hypogammaglobulinemia. Similar to many immunodeficiency...
Autoimmunity | Granulomatous disease | Common variable immunodeficiency | Class-switched memory B cells | Cytopenia | SYSTEMIC-LUPUS-ERYTHEMATOSUS | common variable immunodeficiency | IMMUNOLOGY | SELECTIVE IGA DEFICIENCY | GRANULOMATOUS-DISEASE | granulomatous disease | MEMORY B-CELLS | autoimmunity | HYPOGAMMAGLOBULINEMIA | IMMUNOGLOBULIN DEFICIENCY | class-switched memory B cells | THROMBOCYTOPENIC PURPURA | PATIENT | cytopenia | IMMUNODEFICIENCY | ONSET | Autoimmunity - physiology | Animals | Common Variable Immunodeficiency - therapy | Humans | Autoimmunity - genetics | Common Variable Immunodeficiency - physiopathology | Common Variable Immunodeficiency - genetics | Gastrointestinal diseases | Immunodeficiency
Autoimmunity | Granulomatous disease | Common variable immunodeficiency | Class-switched memory B cells | Cytopenia | SYSTEMIC-LUPUS-ERYTHEMATOSUS | common variable immunodeficiency | IMMUNOLOGY | SELECTIVE IGA DEFICIENCY | GRANULOMATOUS-DISEASE | granulomatous disease | MEMORY B-CELLS | autoimmunity | HYPOGAMMAGLOBULINEMIA | IMMUNOGLOBULIN DEFICIENCY | class-switched memory B cells | THROMBOCYTOPENIC PURPURA | PATIENT | cytopenia | IMMUNODEFICIENCY | ONSET | Autoimmunity - physiology | Animals | Common Variable Immunodeficiency - therapy | Humans | Autoimmunity - genetics | Common Variable Immunodeficiency - physiopathology | Common Variable Immunodeficiency - genetics | Gastrointestinal diseases | Immunodeficiency
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 137, Issue 4, pp. 1206 - 1215.e6
Background Common variable immunodeficiency (CVID) is an antibody deficiency treated with immunoglobulin; however, patients can have noninfectious inflammatory...
Allergy and Immunology | Common variable immunodeficiency | inflammatory complications | innate lymphoid cells | mucosal disease | MULTICENTER | EFFICACY | ABNORMALITIES | BONE-MARROW | SIGNALS | IMMUNOLOGY | HYPERPLASIA | ALLERGY | DISEASE | COHORT | IMMUNODEFICIENCY | BLOOD | Biomarkers - metabolism | Lymphocytes - metabolism | Common Variable Immunodeficiency - immunology | Lung - pathology | Intestines - pathology | Cytokines - metabolism | Enzyme-Linked Immunosorbent Assay | Humans | Middle Aged | Common Variable Immunodeficiency - pathology | Male | Intestines - immunology | Young Adult | Flow Cytometry | Lymphocytes - immunology | Biopsy | Adolescent | Adult | Female | Aged | Real-Time Polymerase Chain Reaction | Lung - immunology | Viral antibodies | Antibodies | Medical colleges | Complications and side effects | Care and treatment | RNA | Analysis | Immunodeficiency | Interferon | Genetic transcription | Biological response modifiers | Antigens | Flow cytometry | Immunoglobulins | Transcription factors | Cytokines | Lung diseases | Mortality | Infections | Inflammation | Expansion | Inflammatory diseases
Allergy and Immunology | Common variable immunodeficiency | inflammatory complications | innate lymphoid cells | mucosal disease | MULTICENTER | EFFICACY | ABNORMALITIES | BONE-MARROW | SIGNALS | IMMUNOLOGY | HYPERPLASIA | ALLERGY | DISEASE | COHORT | IMMUNODEFICIENCY | BLOOD | Biomarkers - metabolism | Lymphocytes - metabolism | Common Variable Immunodeficiency - immunology | Lung - pathology | Intestines - pathology | Cytokines - metabolism | Enzyme-Linked Immunosorbent Assay | Humans | Middle Aged | Common Variable Immunodeficiency - pathology | Male | Intestines - immunology | Young Adult | Flow Cytometry | Lymphocytes - immunology | Biopsy | Adolescent | Adult | Female | Aged | Real-Time Polymerase Chain Reaction | Lung - immunology | Viral antibodies | Antibodies | Medical colleges | Complications and side effects | Care and treatment | RNA | Analysis | Immunodeficiency | Interferon | Genetic transcription | Biological response modifiers | Antigens | Flow cytometry | Immunoglobulins | Transcription factors | Cytokines | Lung diseases | Mortality | Infections | Inflammation | Expansion | Inflammatory diseases
Journal Article