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PloS one, ISSN 1932-6203, 2013, Volume 8, Issue 11, p. e78617
Journal Article
PloS one, ISSN 1932-6203, 2014, Volume 9, Issue 11, p. e112682
Age-related macular degeneration (AMD) is the leading cause of blindness in the Western world. AMD is a multifactorial disorder but complement-mediated... 
SYSTEM | MACULOPATHY | RISK ALLELES | BLUE MOUNTAINS EYE | CLINICAL-TRIAL | CFH | MULTIDISCIPLINARY SCIENCES | FACTOR-H POLYMORPHISM | DIETARY ANTIOXIDANTS | PREVALENCE | RANIBIZUMAB | Retina - drug effects | Macular Degeneration - diet therapy | Macular Degeneration - immunology | Complement C3d - immunology | Epithelial Cells - drug effects | Humans | Complement C5a - metabolism | Male | Retina - immunology | Complement C3d - metabolism | Complement Factor B - metabolism | Zinc Sulfate - administration & dosage | Aged, 80 and over | Female | Epithelial Cells - cytology | Complement Activation - drug effects | Retinal Pigment Epithelium - drug effects | Complement Factor H - immunology | Gene Expression | Complement C3 - metabolism | Cells, Cultured | Macular Degeneration - blood | Proteins - immunology | Complement C3 - immunology | Proteins - genetics | Complement Factor H - metabolism | Copper Sulfate - administration & dosage | Epithelial Cells - immunology | Retinal Pigment Epithelium - immunology | Complement Factor B - immunology | Aged | Complement C5a - immunology | Mutation | Dietary Supplements | Retina - pathology | Retinal Pigment Epithelium - cytology | Macular Degeneration - pathology | Laboratories | Complement component C5a | Retina | Systematic review | Activation | Complement | Sulfates | Peritoneal dialysis | Macular degeneration | Complement factor H | Membrane attack complex | Supplementation | Age | Dietary supplements | Inflammation | Patients | Fatty acids | Age related diseases | Zinc | Hypotheses | Complement activation | Complement component C3 | Blindness | Anaphylatoxin C5a | Eye diseases | Catabolism | Basic Medicine | Other Basic Medicine | Andra medicinska och farmaceutiska grundvetenskaper | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
Clinical and experimental immunology, ISSN 0009-9104, 2015, Volume 181, Issue 3, pp. 518 - 527
Summary The interaction between neutrophils and activation of alternative complement pathway plays a pivotal role in the pathogenesis of anti‐neutrophil... 
neutrophil extracellular traps | complement | ANCA | vasculitis | alternative complement pathway | Complement | Vasculitis | Alternative complement pathway | Neutrophil extracellular traps | GLOMERULONEPHRITIS | ANTIBODY-ASSOCIATED VASCULITIS | PROTEIN C3 | DENDRITIC CELLS | DEPOSITION | IMMUNOLOGY | INHIBITION | DISEASE | ANTINEUTROPHIL CYTOPLASMIC AUTOANTIBODIES | GENERATION | Neutrophils - cytology | Complement Membrane Attack Complex - metabolism | Extracellular Traps - metabolism | Humans | Serum - drug effects | Complement C5a - metabolism | Immunoblotting | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - blood | Complement Membrane Attack Complex - immunology | Complement Activation - immunology | Antibodies, Antineutrophil Cytoplasmic - immunology | Serum - immunology | Antibodies, Antineutrophil Cytoplasmic - metabolism | Complement C3b - metabolism | Extracellular Traps - immunology | Complement Factor B - metabolism | Properdin - immunology | Extracellular Traps - drug effects | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - metabolism | Complement C3a - metabolism | Neutrophils - metabolism | Complement Activation - drug effects | Cells, Cultured | Neutrophils - immunology | Hot Temperature | Egtazic Acid - immunology | Microscopy, Confocal | Egtazic Acid - pharmacology | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - immunology | Complement Pathway, Alternative - drug effects | Complement Pathway, Alternative - immunology | Complement Factor B - immunology | Complement C3a - immunology | Complement C5a - immunology | Complement C3b - immunology | Properdin - metabolism | Translational
Journal Article
The Journal of experimental medicine, ISSN 1540-9538, 2010, Volume 207, Issue 4, pp. 793 - 806
Journal Article
The Journal of immunology (1950), ISSN 1550-6606, 2014, Volume 192, Issue 6, pp. 2837 - 2845
Inflammation is associated with development of atherosclerosis, and cholesterol crystals (CC) have long been recognized as a hallmark of atherosclerotic... 
ATHEROSCLEROTIC LESIONS | TUMOR-NECROSIS-FACTOR | C5A RECEPTOR | MEMBRANE ATTACK | STERILE INFLAMMATION | EPITHELIAL-CELLS | CARDIOVASCULAR EVENTS | INTERLEUKIN-1-BETA | OXIDATIVE BURST | ANAPHYLATOXINS | IMMUNOLOGY | Inflammasomes - metabolism | Reactive Oxygen Species - metabolism | Complement C1q - immunology | Humans | Complement Pathway, Classical - drug effects | Complement C5a - metabolism | Complement System Proteins - immunology | Caspase 1 - metabolism | Monocytes - metabolism | Caspase 1 - immunology | Macrophage-1 Antigen - immunology | Monocytes - immunology | Interleukin-1beta - genetics | Complement Activation - immunology | Complement C1q - metabolism | Complement System Proteins - metabolism | Inflammasomes - drug effects | Reactive Oxygen Species - immunology | Complement C5 - immunology | Tumor Necrosis Factor-alpha - immunology | Macrophage-1 Antigen - metabolism | Complement Activation - drug effects | Cytokines - immunology | Interleukin-1beta - secretion | Complement C5 - metabolism | Tumor Necrosis Factor-alpha - secretion | Cells, Cultured | Cytokines - secretion | Phagocytosis - immunology | Interleukin-1beta - immunology | Cholesterol - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Monocytes - drug effects | Complement Pathway, Classical - immunology | Microscopy, Confocal | Complement Pathway, Alternative - drug effects | Complement Pathway, Alternative - immunology | Inflammasomes - immunology | Cholesterol - pharmacology | Complement C5a - immunology
Journal Article
PloS one, ISSN 1932-6203, 04/2014, Volume 9, Issue 4, p. e94965
Journal Article
Kidney international, ISSN 0085-2538, 2018, Volume 94, Issue 4, pp. 689 - 700
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 5/2013, Volume 110, Issue 21, pp. 8650 - 8655
Complement C1q is a hexameric molecule assembled from 18 polypeptide chains of three different types encoded by three genes. This versatile recognition protein... 
Proteins | Molecules | Cell lines | Materials | Cell aggregates | Ligands | Mass spectroscopy | Biochemistry | Electron microscopy | Molecular chains | C1 complex | Protein engineering | Innate immunity | B-CHAIN | ACTIVATION | 1ST COMPONENT | PROTEIN | MULTIDISCIPLINARY SCIENCES | LONG PENTRAXIN PTX3 | LIGAND-RECOGNITION | MANNAN-BINDING LECTIN | protein engineering | innate immunity | STRUCTURAL BASIS | PATHWAY | SUBCOMPONENT C1Q | Surface Plasmon Resonance | Complement C1r - genetics | Calcium - metabolism | Humans | Complement C1s - metabolism | Mutation, Missense | Complement C1q - metabolism | Complement C1r - metabolism | Complement C1s - genetics | Complement C1r - chemistry | Complement C1s - chemistry | C-Reactive Protein - metabolism | HEK293 Cells | Protein Structure, Quaternary | Binding Sites | Complement C1q - chemistry | Complement Activation - physiology | Protein Structure, Tertiary | Recombinant Proteins - metabolism | Gene Expression | Immunoglobulin G - chemistry | Serum Amyloid P-Component - chemistry | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Complement C1q - genetics | C-Reactive Protein - chemistry | Serum Amyloid P-Component - metabolism | Amino Acid Substitution | Immunoglobulin G - metabolism | Protein Binding - physiology | Bone morphogenetic proteins | Polypeptides | Research | Properties | Proteases | Protein binding | C-Reactive Protein | Calcium | Complement Activation | Immunoglobulin G | Biochemistry, Molecular Biology | Serum Amyloid P-Component | Recombinant Proteins | Complement C1q | Complement C1s | Complement C1r | Life Sciences | Protein Binding | Biomolecules | Biological Sciences
Journal Article
Nature communications, ISSN 2041-1723, 2018, Volume 9, Issue 1, pp. 5316 - 11
Journal Article