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1. Full Text C3 glomerulopathy: consensus report
by Pickering, Matthew C and D'Agati, Vivette D and Nester, Carla M and Smith, Richard J and Haas, Mark and Appel, Gerald B and Alpers, Charles E and Bajema, Ingeborg M and Bedrosian, Camille and Braun, Michael and Doyle, Mittie and Fakhouri, Fadi and Fervenza, Fernando C and Fogo, Agnes B and Frémeaux-Bacchi, Véronique and Gale, Daniel P and Goicoechea de Jorge, Elena and Griffin, Gene and Harris, Claire L and Michael Holers, V and Johnson, Sally and Lavin, Peter J and Medjeral-Thomas, Nicholas and Paul Morgan, B and Nast, Cynthia C and Noel, Laure-Hélène and Keith Peters, D and Rodríguez de Córdoba, Santiago and Servais, Aude and Sethi, Sanjeev and Song, Wen-Chao and Tamburini, Paul and Thurman, Joshua M and Zavros, Michael and Terence Cook, H
Kidney international, ISSN 0085-2538, 12/2013, Volume 84, Issue 6, pp. 1079 - 1089
immunology and pathology | complement | glomerulonephritis | clinical nephrology | clinical immunology | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Complement C3 - analysis | Predictive Value of Tests | Glomerulonephritis - therapy | Prognosis | Humans | Cooperative Behavior | Glomerulonephritis - diagnosis | Glomerulonephritis - immunology | International Cooperation | Kidney Glomerulus - pathology | Biopsy | Biomedical Research | Kidney Glomerulus - immunology | Index Medicus | Meeting Report
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2. Full Text C3 glomerulopathy-associated CFHR1 mutation alters FHR oligomerization and complement regulation
by Tortajada, Agustín and Yébenes, Hugo and Abarrategui-Garrido, Cynthia and Anter, Jaouad and García-Fernández, Jesús M and Martínez-Barricarte, Rubén and Alba-Domínguez, María and Malik, Talat H and Bedoya, Rafael and Pérez, Rocío Cabrera and Trascasa, Margarita López and Pickering, Matthew C and Harris, Claire L and Sánchez-Corral, Pilar and Llorca, Oscar and De Córdoba, Santiago Rodríguez
The Journal of clinical investigation, ISSN 0021-9738, 06/2013, Volume 123, Issue 6, pp. 2434 - 2446
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Gene Duplication | Hemolysis | Immobilized Proteins - chemistry | Kidney - pathology | Complement C3 - metabolism | Humans | Middle Aged | Protein Multimerization | Complement C3b Inactivator Proteins - genetics | Complement C3b Inactivator Proteins - chemistry | Male | Sequence Analysis, DNA | Kidney Diseases - genetics | Complement System Proteins - metabolism | Complement C3b Inactivator Proteins - metabolism | Complement C3 - chemistry | Pedigree | Immobilized Proteins - metabolism | Protein Structure, Quaternary | Complement System Proteins - isolation & purification | Protein Binding | Female | Mutagenesis, Insertional | Child | Glomerulonephritis | Complement factor H | Gene mutations | Physiological aspects | Causes of | Genetic aspects | Research | Proteins | Competition | Plasma | Carbohydrates | Mutation | Crystal structure | Index Medicus | Abridged Index Medicus | Avidity
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3. Full Text The tick-over theory revisited: Formation and regulation of the soluble alternative complement C3 convertase (C3(H 2O)Bb)
by Bexborn, Fredrik and Andersson, Per Ola and Chen, Hui and Nilsson, Bo and Ekdahl, Kristina N
Molecular immunology, ISSN 0161-5890, 2008, Volume 45, Issue 8, pp. 2370 - 2379
Alternative pathway convertase | C3(H 2O) | C3b | Factor B | Fluorescence resonance energy transfer (FRET) | Fluid phase | C3(H | Biochemistry & Molecular Biology | Immunology | Life Sciences & Biomedicine | Science & Technology | Complement Factor H - immunology | Complement Factor I - immunology | Complement C3-C5 Convertases - metabolism | Molecular Weight | Enzyme-Linked Immunosorbent Assay | Electrophoresis, Polyacrylamide Gel | Humans | Solubility | Blotting, Western | Complement C3-C5 Convertases - immunology | Hydrolysis | Complement C3 Convertase, Alternative Pathway | Models, Immunological | Solutions | Time Factors | Complement Factor B - immunology | Fluorescence Resonance Energy Transfer | Indicators and Reagents | Spectrum Analysis | Complement C3b - immunology | Index Medicus | C3(H2O) | factor B | fluorescence resonance energy transfer (FRET) | fluid phase
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4. Full Text C3 glomerulopathy associated with monoclonal Ig is a distinct subtype
by Ravindran, Aishwarya and Fervenza, Fernando C and Smith, Richard J.H and Sethi, Sanjeev
Kidney international, ISSN 0085-2538, 07/2018, Volume 94, Issue 1, pp. 178 - 186
dense deposit disease | monoclonal Ig | C3 glomerulopathy | alternative pathway of complement | C3 glomerulonephritis | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Complement C3 - analysis | Age Factors | Follow-Up Studies | Immunoglobulin G - blood | Humans | Middle Aged | Child, Preschool | Male | Glomerulonephritis, Membranoproliferative - blood | Young Adult | Paraproteinemias - pathology | Immunoglobulin G - immunology | Aged, 80 and over | Adult | Female | Child | Antibodies, Monoclonal - immunology | Paraproteinemias - immunology | Glomerulonephritis, Membranoproliferative - pathology | Kidney Glomerulus - pathology | Complement C3 - immunology | Glomerulonephritis, Membranoproliferative - immunology | Biopsy | Complement Pathway, Alternative - immunology | Adolescent | Aged | Paraproteinemias - blood | Kidney Glomerulus - immunology
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5. Full Text Toward a working definition of C3 glomerulopathy by immunofluorescence
by Hou, Jean and Markowitz, Glen S and Bomback, Andrew S and Appel, Gerald B and Herlitz, Leal C and Barry Stokes, M and D'Agati, Vivette D
Kidney international, ISSN 0085-2538, 2014, Volume 85, Issue 2, pp. 450 - 456
Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Complement C3 - analysis | Glomerulonephritis, Membranoproliferative - pathology | Predictive Value of Tests | Glomerulonephritis, Membranoproliferative - classification | Humans | Immunoglobulin M - analysis | Biomarkers - analysis | Terminology as Topic | Male | Kidney Glomerulus - pathology | Complement C1q - analysis | Glomerulonephritis, Membranoproliferative - immunology | Biopsy | Fluorescent Antibody Technique | Adult | Female | Immunoglobulin G - analysis | Retrospective Studies | Kidney Glomerulus - immunology | Immunoglobulin A - analysis | Index Medicus
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6. Full Text C3 Glomerulopathy: Ten Years' Experience at Mayo Clinic
by Ravindran, Aishwarya and Fervenza, Fernando C and Smith, Richard J.H and De Vriese, An S and Sethi, Sanjeev
Mayo Clinic proceedings, ISSN 0025-6196, 08/2018, Volume 93, Issue 8, pp. 991 - 1008
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Glucocorticoids - therapeutic use | Hematuria - epidemiology | Autoantibodies - blood | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Child, Preschool | Male | Minnesota - epidemiology | Genetic Variation | Young Adult | Paraproteinemias - epidemiology | Immunoglobulins - blood | Aged, 80 and over | Adult | Female | Child | Complement C3 - genetics | Autoimmune Diseases - epidemiology | Infections - epidemiology | Proteinuria - epidemiology | Glomerulonephritis - blood | Glomerulonephritis - genetics | Complement C3 Nephritic Factor - analysis | Disease Progression | Glomerulonephritis - drug therapy | Complement System Proteins | Kidney Failure, Chronic - epidemiology | Adolescent | Creatinine - blood | Nephrotic Syndrome - epidemiology | Aged | Complement Factor H - genetics | Variables | Pathology | Immunoglobulins | Microscopy | Biopsy | Kidney diseases | Age | Index Medicus | Abridged Index Medicus
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7. Full Text C3 glomerulonephritis: clinicopathological findings, complement abnormalities, glomerular proteomic profile, treatment, and follow-up
by Sethi, Sanjeev and Fervenza, Fernando C and Zhang, Yuzhou and Zand, Ladan and Vrana, Julie A and Nasr, Samih H and Theis, Jason D and Dogan, Ahmet and Smith, Richard J.H
Kidney international, ISSN 0085-2538, 08/2012, Volume 82, Issue 4, pp. 465 - 473
C3GN | proteomics | C3 glomerulopathy | MPGN | alternative pathway of complement | C3 glomerulonephritis | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Glomerulonephritis | Nephrology. Urinary tract diseases | Biological and medical sciences | Medical sciences | Nephropathies. Renovascular diseases. Renal failure | Complement C3 - analysis | Predictive Value of Tests | Recurrence | Follow-Up Studies | Humans | Middle Aged | Complement System Proteins - immunology | Laser Capture Microdissection | Molecular Sequence Data | Male | Glomerulonephritis, Membranoproliferative - complications | Complement System Proteins - analysis | Young Adult | Time Factors | DNA Mutational Analysis | Mass Spectrometry | Adult | Autoantibodies - analysis | Complement System Proteins - genetics | Female | Complement Pathway, Alternative - genetics | Proteomics - methods | Child | Amino Acid Sequence | Glomerulonephritis, Membranoproliferative - pathology | Genetic Predisposition to Disease | Proteinuria - immunology | Treatment Outcome | Complement C3 Nephritic Factor - analysis | Hematuria - immunology | Kidney Transplantation | Minnesota | Kidney Glomerulus - pathology | Glomerulonephritis, Membranoproliferative - therapy | Glomerulonephritis, Membranoproliferative - genetics | Glomerulonephritis, Membranoproliferative - immunology | Biopsy | Adolescent | Aged | Kidney Glomerulus - immunology | Mutation | Complement Factor H - genetics | Index Medicus
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8. Full Text ADAPT: An Algorithm Incorporating PRO‐C3 Accurately Identifies Patients With NAFLD and Advanced Fibrosis
by Daniels, Samuel J and Leeming, Diana J and Eslam, Mohammed and Hashem, Ahmed M and Nielsen, Mette J and Krag, Aleksander and Karsdal, Morten A and Grove, Jane I and Neil Guha, Indra and Kawaguchi, Takumi and Torimura, Takuji and McLeod, Duncan and Akiba, Jun and Kaye, Philip and de Boer, Bastiaan and Aithal, Guruprasad P and Adams, Leon A and George, Jacob
Hepatology (Baltimore, Md.), ISSN 0270-9139, 03/2019, Volume 69, Issue 3, pp. 1075 - 1086
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Complement C3 - analysis | Severity of Illness Index | Non-alcoholic Fatty Liver Disease - pathology | Liver Cirrhosis - diagnosis | Humans | Middle Aged | Male | Liver Cirrhosis - blood | Non-alcoholic Fatty Liver Disease - blood | Algorithms | Biopsy | Non-alcoholic Fatty Liver Disease - diagnosis | Liver Cirrhosis - pathology | Adult | Female | Cohort Studies | Collagen (type I) | Liver diseases | Fatty liver | Diabetes mellitus | Phenotyping | Fibrosis | Biomarkers | Collagen (type III) | Aspartate aminotransferase | Platelets | Index Medicus
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9. Full Text C3 glomerulonephritis and dense deposit disease share a similar disease course in a large United States cohort of patients with C3 glomerulopathy
by Bomback, Andrew S and Santoriello, Dominick and Avasare, Rupali S and Regunathan-Shenk, Renu and Canetta, Pietro A and Ahn, Wooin and Radhakrishnan, Jai and Marasa, Maddalena and Rosenstiel, Paul E and Herlitz, Leal C and Markowitz, Glen S and D’Agati, Vivette D and Appel, Gerald B
Kidney international, ISSN 0085-2538, 04/2018, Volume 93, Issue 4, pp. 977 - 985
dense deposit disease | glomerulonephritis | C3 glomerulopathy | alternative complement pathway | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Complement C3 - analysis | United States - epidemiology | Kidney - pathology | Humans | Middle Aged | Kidney - immunology | Male | Atrophy | Renal Insufficiency, Chronic - epidemiology | Young Adult | Time Factors | Kidney Failure, Chronic - pathology | Adult | Female | Retrospective Studies | Complement Pathway, Alternative - genetics | Kidney - physiopathology | Glomerulonephritis, Membranoproliferative - pathology | Kidney Failure, Chronic - immunology | Renal Insufficiency, Chronic - immunology | Risk Factors | Biomarkers - analysis | Treatment Outcome | Glomerulonephritis, Membranoproliferative - therapy | Remission Induction | Disease Progression | Renal Insufficiency, Chronic - pathology | Autoantibodies - immunology | Glomerulonephritis, Membranoproliferative - immunology | Kidney Failure, Chronic - epidemiology | Biopsy | Complement Pathway, Alternative - immunology | Adolescent | Fibrosis | Glomerulonephritis, Membranoproliferative - epidemiology | Glomerulonephritis | End-stage renal disease | Pediatrics | Autoantibodies | Disease | Patients | Glomerular filtration rate | Histopathology | Microscopy | Complement component C3 | Remission | Kidney diseases | Age | Index Medicus
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10. Full Text Redefining C3 glomerulopathy: ‘C3 only’ is a bridge too far
by Larsen, Christopher P and Walker, Patrick D
Kidney international, ISSN 0085-2538, 02/2013, Volume 83, Issue 2, pp. 331 - 332
Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Complement C3 - analysis | Complement C3 - metabolism | Humans | Glomerulonephritis - genetics | Male | Complement System Proteins - analysis | Complement System Proteins - metabolism | Glomerulonephritis, Membranoproliferative - genetics | Glomerulonephritis, Membranoproliferative - immunology | Proteomics | Complement System Proteins - genetics | Female | Complement Pathway, Alternative - genetics | Kidney Glomerulus - immunology | Mutation | Index Medicus
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11. Full Text C5 nephritic factors drive the biological phenotype of C3 glomerulopathies
by Marinozzi, Maria-Chiara and Chauvet, Sophie and Le Quintrec, Moglie and Mignotet, Morgane and Petitprez, Florent and Legendre, Christophe and Cailliez, Mathilde and Deschenes, Georges and Fischbach, Michel and Karras, Alexandre and Nobili, Francois and Pietrement, Christine and Dragon-Durey, Marie-Agnes and Fakhouri, Fadi and Roumenina, Lubka T and Fremeaux-Bacchi, Veronique
Kidney international, ISSN 0085-2538, 11/2017, Volume 92, Issue 5, pp. 1232 - 1241
complement | nephritic factor | membranoproliferative glomerulonephritis | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Complement C3 Nephritic Factor - genetics | Follow-Up Studies | Humans | Middle Aged | Male | Complement C3 Nephritic Factor - immunology | Glomerulonephritis, Membranoproliferative - blood | Young Adult | Adult | Female | Child | Complement C3 Convertase, Alternative Pathway - immunology | Serologic Tests | Complement C3-C5 Convertases - metabolism | Kaplan-Meier Estimate | Complement C3 Nephritic Factor - analysis | Complement C3-C5 Convertases - immunology | Glomerulonephritis, Membranoproliferative - genetics | Glomerulonephritis, Membranoproliferative - immunology | Phenotype | Glomerulonephritis, Membranoproliferative - mortality | Complement Pathway, Alternative - immunology | Adolescent | Complement Membrane Attack Complex - analysis | Properdin - metabolism | Index Medicus | Life Sciences | Human health and pathology | Urology and Nephrology
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