Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (22028) 22028
Publication (2373) 2373
Book Review (208) 208
Book Chapter (150) 150
Conference Proceeding (50) 50
Book / eBook (39) 39
Dissertation (13) 13
Web Resource (6) 6
Magazine Article (5) 5
Paper (4) 4
Data Set (3) 3
Newsletter (2) 2
Presentation (2) 2
Streaming Video (2) 2
Electronic Resource (1) 1
Trade Publication Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (15578) 15578
female (7335) 7335
animals (7127) 7127
male (7096) 7096
index medicus (6840) 6840
complement (5326) 5326
immunology (5039) 5039
complement c3 - analysis (4825) 4825
adult (4638) 4638
middle aged (3997) 3997
complement activation (3416) 3416
mice (2907) 2907
aged (2482) 2482
adolescent (2043) 2043
activation (1998) 1998
proteins (1950) 1950
complement c3 - metabolism (1745) 1745
complement system proteins - analysis (1691) 1691
immunoglobulin g - analysis (1674) 1674
analysis (1664) 1664
inflammation (1643) 1643
child (1570) 1570
complement c4 - analysis (1537) 1537
biochemistry & molecular biology (1529) 1529
research article (1454) 1454
fluorescent antibody technique (1201) 1201
expression (1192) 1192
rats (1146) 1146
disease (1142) 1142
article (1089) 1089
immunoglobulins - analysis (1089) 1089
research (1087) 1087
immunoglobulin m - analysis (1062) 1062
complement system proteins - immunology (1046) 1046
antibodies (1041) 1041
complement system proteins - metabolism (1006) 1006
child, preschool (952) 952
enzyme-linked immunosorbent assay (946) 946
complement component c3 (920) 920
complement c3 - immunology (907) 907
urology & nephrology (899) 899
risk factors (890) 890
medicine (866) 866
cell biology (859) 859
lupus erythematosus, systemic - immunology (856) 856
health aspects (854) 854
time factors (854) 854
mice, inbred c57bl (851) 851
phagocytosis (846) 846
molecular sequence data (825) 825
physiological aspects (815) 815
disease models, animal (809) 809
amino acid sequence (791) 791
rheumatology (783) 783
multidisciplinary sciences (782) 782
innate immunity (773) 773
transplantation (771) 771
immunoglobulin a - analysis (769) 769
protein binding (763) 763
medicine, research & experimental (752) 752
gene expression (751) 751
alternative pathway (750) 750
pathology (748) 748
genetic aspects (745) 745
complement system (736) 736
cells (720) 720
biopsy (717) 717
immune system (706) 706
glomerulonephritis - immunology (701) 701
systemic lupus erythematosus (701) 701
complement c3 - genetics (700) 700
cells, cultured (698) 698
macular degeneration (698) 698
immunoglobulins (673) 673
hematology (665) 665
microbiology (665) 665
complement c3 (652) 652
autoantibodies (642) 642
neurosciences (640) 640
immunohistochemistry (637) 637
antigen-antibody complex - analysis (636) 636
surgery (634) 634
system (631) 631
genes (626) 626
aged, 80 and over (623) 623
c-reactive protein (621) 621
pathogenesis (614) 614
rabbits (609) 609
protein (606) 606
young adult (604) 604
immunity (598) 598
pregnancy (598) 598
case-control studies (597) 597
immunoglobulin g (587) 587
complement activation - drug effects (582) 582
complement activation - immunology (578) 578
binding (574) 574
science (571) 571
infant (568) 568
cytokines (563) 563
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (27) 27
Online Resources - Online (6) 6
Collection Dvlpm't (Acquisitions) - Vendor file (2) 2
Gerstein Science - Circulation Desk (1) 1
Gerstein Science - Reference (1) 1
Robarts - Stacks (1) 1
Trinity College (John W Graham) - Stacks (1) 1
Trinity College (John W Graham) - Storage (1) 1
UofT at Mississauga - Stacks (1) 1
UofT at Scarborough - Stacks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (20840) 20840
German (240) 240
French (195) 195
Japanese (169) 169
Russian (138) 138
Italian (128) 128
Spanish (120) 120
Chinese (108) 108
Polish (68) 68
Czech (30) 30
Romanian (23) 23
Portuguese (22) 22
Bulgarian (14) 14
Slovak (13) 13
Croatian (12) 12
Serbian (11) 11
Danish (4) 4
Turkish (3) 3
Dutch (2) 2
Korean (2) 2
Bosnian (1) 1
Hungarian (1) 1
Lithuanian (1) 1
Norwegian (1) 1
Persian (1) 1
Ukrainian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text C3 glomerulopathy: consensus report
by Pickering, Matthew C and D'Agati, Vivette D and Nester, Carla M and Smith, Richard J and Haas, Mark and Appel, Gerald B and Alpers, Charles E and Bajema, Ingeborg M and Bedrosian, Camille and Braun, Michael and Doyle, Mittie and Fakhouri, Fadi and Fervenza, Fernando C and Fogo, Agnes B and Frémeaux-Bacchi, Véronique and Gale, Daniel P and Goicoechea de Jorge, Elena and Griffin, Gene and Harris, Claire L and Michael Holers, V and Johnson, Sally and Lavin, Peter J and Medjeral-Thomas, Nicholas and Paul Morgan, B and Nast, Cynthia C and Noel, Laure-Hélène and Keith Peters, D and Rodríguez de Córdoba, Santiago and Servais, Aude and Sethi, Sanjeev and Song, Wen-Chao and Tamburini, Paul and Thurman, Joshua M and Zavros, Michael and Terence Cook, H
Kidney International, ISSN 0085-2538, 12/2013, Volume 84, Issue 6, pp. 1079 - 1089
C3 glomerulopathy is a recently introduced pathological entity whose original definition was glomerular pathology characterized by C3 accumulation with absent... 
immunology and pathology | complement | glomerulonephritis | clinical nephrology | clinical immunology | ECULIZUMAB | ACTIVATION | MECHANISM | CLASSIFICATION | COMPLEMENT FACTOR-H | PROVIDES INSIGHTS | MUTATION | DYSREGULATION | UROLOGY & NEPHROLOGY | MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS | DENSE-DEPOSIT DISEASE | Complement C3 - analysis | Predictive Value of Tests | Glomerulonephritis - therapy | Prognosis | Humans | Cooperative Behavior | Glomerulonephritis - diagnosis | Glomerulonephritis - immunology | International Cooperation | Kidney Glomerulus - pathology | Biopsy | Biomedical Research | Kidney Glomerulus - immunology | Meeting Report
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Analysis of C3 nephritic factors by ELISA
by Skattum, Lillemor
Methods in Molecular Biology, ISSN 1064-3745, 2019, Volume 1901, pp. 177 - 182
Autoantibodies to the C3 convertase of the alternative pathway of complement, called C3 nephritic factors (C3NeF), cause persistently low C3 in the circulation... 
Alternative pathway convertase | Autoantibodies to complement | C3 nephritic factors | C3 glomerulopathy | ELISA
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Toward a working definition of C3 glomerulopathy by immunofluorescence
by Hou, Jean and Markowitz, Glen S and Bomback, Andrew S and Appel, Gerald B and Herlitz, Leal C and Barry Stokes, M and D'Agati, Vivette D
Kidney International, ISSN 0085-2538, 2014, Volume 85, Issue 2, pp. 450 - 456
Precise immunofluorescence criteria for C3 glomerulopathy remain to be defined. Here we tested hierarchical immunofluorescence criteria with varying stringency... 
ECULIZUMAB | DENSE DEPOSIT DISEASE | COMPLEMENT ABNORMALITIES | UROLOGY & NEPHROLOGY | CLASSIFICATION | MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS | MPGN | Complement C3 - analysis | Glomerulonephritis, Membranoproliferative - pathology | Predictive Value of Tests | Glomerulonephritis, Membranoproliferative - classification | Humans | Immunoglobulin M - analysis | Biomarkers - analysis | Terminology as Topic | Male | Kidney Glomerulus - pathology | Complement C1q - analysis | Glomerulonephritis, Membranoproliferative - immunology | Biopsy | Fluorescent Antibody Technique | Adult | Female | Immunoglobulin G - analysis | Retrospective Studies | Kidney Glomerulus - immunology | Immunoglobulin A - analysis
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text C3 glomerulonephritis: clinicopathological findings, complement abnormalities, glomerular proteomic profile, treatment, and follow-up
by Sethi, Sanjeev and Fervenza, Fernando C and Zhang, Yuzhou and Zand, Ladan and Vrana, Julie A and Nasr, Samih H and Theis, Jason D and Dogan, Ahmet and Smith, Richard J.H
Kidney International, ISSN 0085-2538, 08/2012, Volume 82, Issue 4, pp. 465 - 473
C3 glomerulonephritis (C3GN) is a recently described disorder that typically results from abnormalities in the alternative pathway (AP) of complement. Here, we... 
C3GN | proteomics | C3 glomerulopathy | MPGN | alternative pathway of complement | C3 glomerulonephritis | MACULAR DEGENERATION | CLASSIFICATION | RISK | PROTEIN 5 | DENSE DEPOSIT DISEASE | ALTERNATIVE PATHWAY | UROLOGY & NEPHROLOGY | MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS | Complement C3 - analysis | Predictive Value of Tests | Recurrence | Follow-Up Studies | Humans | Middle Aged | Complement System Proteins - immunology | Laser Capture Microdissection | Molecular Sequence Data | Male | Glomerulonephritis, Membranoproliferative - complications | Complement System Proteins - analysis | Young Adult | Time Factors | DNA Mutational Analysis | Mass Spectrometry | Adult | Autoantibodies - analysis | Complement System Proteins - genetics | Female | Complement Pathway, Alternative - genetics | Proteomics - methods | Child | Amino Acid Sequence | Glomerulonephritis, Membranoproliferative - pathology | Genetic Predisposition to Disease | Proteinuria - immunology | Treatment Outcome | Complement C3 Nephritic Factor - analysis | Hematuria - immunology | Kidney Transplantation | Minnesota | Kidney Glomerulus - pathology | Glomerulonephritis, Membranoproliferative - therapy | Glomerulonephritis, Membranoproliferative - genetics | Glomerulonephritis, Membranoproliferative - immunology | Biopsy | Adolescent | Aged | Kidney Glomerulus - immunology | Mutation | Complement Factor H - genetics
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Mutations in complement C3 predispose to development of atypical hemolytic uremic syndrome
by Frémeaux-Bacchi, Veronique and Miller, Elizabeth C and Liszewski, M. Kathryn and Strain, Lisa and Blouin, Jacques and Brown, Alison L and Moghal, Nadeem and Kaplan, Bernard S and Weiss, Robert A and Lhotta, Karl and Kapur, Gaurav and Mattoo, Tej and Nivet, Hubert and Wong, William and Gie, Sophie and De Ligny, Bruno Hurault and Fischbach, Michel and Gupta, Ritu and Hauhart, Richard and Meunier, Vincent and Loirat, Chantal and Dragon-Durey, Marie-Agnès and Fridman, Wolf H and Janssen, Bert J. C and Goodship, Timothy H. J and Atkinson, John P
Blood, ISSN 0006-4971, 12/2008, Volume 112, Issue 13, pp. 4948 - 4952
Atypical hemolytic uremic syndrome (aHUS) is a disease of complement dysregulation. In approximately 50% of patients, mutations have been described in the... 
GENE | FACTOR-H | FACTOR-I | MCP | DEFICIENCIES | CD46 | HEMATOLOGY | MOLECULAR-BASIS | COMPONENT C3 | INSIGHTS | REVEALS | Complement C3 - analysis | Genetic Predisposition to Disease | Hemolytic-Uremic Syndrome - etiology | Humans | Child, Preschool | Infant | Codon, Nonsense | Mutation, Missense | Hemolytic-Uremic Syndrome - immunology | Young Adult | Hemolytic-Uremic Syndrome - genetics | DNA Mutational Analysis | Adolescent | Adult | Heterozygote | Mutation | Child | Complement C3 - genetics | Hemostasis, Thrombosis, and Vascular Biology
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Treatment of B-cell disorder improves renal outcome of patients with monoclonal gammopathy-associated C3 glomerulopathy
by Chauvet, Sophie and Frémeaux-Bacchi, Véronique and Petitprez, Florent and Karras, Alexandre and Daniel, Laurent and Burtey, Stéphane and Choukroun, Gabriel and Delmas, Yahsou and Guerrot, Dominique and François, Arnaud and Le Quintrec, Moglie and Javaugue, Vincent and Ribes, David and Vrigneaud, Laurence and Arnulf, Bertrand and Goujon, Jean Michel and Ronco, Pierre and Touchard, Guy and Bridoux, Frank
Blood, ISSN 0006-4971, 03/2017, Volume 129, Issue 11, pp. 1437 - 1447
The high frequency of monoclonal gammopathy in adult patients with C3 glomerulopathy (C3G) emphasizes the role of monoclonal immunoglobulin (MIg) in the... 
GLOMERULONEPHRITIS | ECULIZUMAB | CRITERIA | COMPLEMENT | HEMOLYTIC-UREMIC SYNDROME | CLASSIFICATION | FACTOR-H | HEMATOLOGY | DENSE-DEPOSIT DISEASE | Complement C3 - analysis | Paraproteinemias - drug therapy | Humans | Middle Aged | Kidney Diseases - drug therapy | Treatment Outcome | Paraproteinemias - complications | Kidney Glomerulus - pathology | Molecular Targeted Therapy | Young Adult | Drug Therapy - methods | Aged, 80 and over | Adult | Aged | Retrospective Studies | B-Lymphocytes - pathology | Kidney Diseases - etiology | France | Cohort Studies | Databases, Factual | Life Sciences | Human health and pathology | Hematology | Urology and Nephrology
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text C3 Glomerulopathy: Clinicopathologic Features and Predictors of Outcome
by Nicholas R. Medjeral-Thomas and Michelle M. O’Shaughnessy and John A. O’Regan and Carol Traynor and Michael Flanagan and Limy Wong and Chia Wei Teoh and Atif Awan and Mary Waldron and Tom Cairns and Patrick O’Kelly and Anthony M. Dorman and Matthew C. Pickering and Peter J. Conlon and H. Terence Cook
Clinical Journal of the American Society of Nephrology, ISSN 1555-9041, 01/2014, Volume 9, Issue 1, pp. 46 - 53
Background and objectivesThe term C3 glomerulopathy describes renal disorders characterized by the presence of glomerular deposits composed of C3 in the... 
GLOMERULONEPHRITIS | ECULIZUMAB | COMPLEMENT FACTOR-H | ABNORMALITIES | MUTATION | UROLOGY & NEPHROLOGY | RISK | PATIENT | PROTEIN 5 | DEFICIENCY | DENSE-DEPOSIT DISEASE | Complement C3 - analysis | Prognosis | Kidney - pathology | Humans | Middle Aged | Kidney - immunology | Glomerulonephritis - diagnosis | Male | Glomerulonephritis, Membranoproliferative - complications | Young Adult | Time Factors | Ireland | Adult | Female | Retrospective Studies | Child | Glomerulonephritis, Membranoproliferative - pathology | Risk Factors | Biomarkers - analysis | Kaplan-Meier Estimate | Proportional Hazards Models | Glomerulonephritis - immunology | Glomerulonephritis - mortality | Glomerulonephritis - complications | Disease Progression | Glomerulonephritis, Membranoproliferative - immunology | Biopsy | Glomerulonephritis, Membranoproliferative - mortality | Glomerulonephritis - pathology | Adolescent | London | Glomerulonephritis, Membranoproliferative - diagnosis | Kidney Failure, Chronic - etiology | Original
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Eculizumab for Treatment of Rapidly Progressive C3 Glomerulopathy
by Le Quintrec, Moglie, MD, PhD and Lionet, Arnaud, MD and Kandel, Christine, MD and Bourdon, Franck, MD and Gnemmi, Viviane, MD and Colombat, Magali, MD, PhD and Goujon, Jean-Michel, MD and Frémeaux-Bacchi, Véronique, MD, PhD and Fakhouri, Fadi, MD, PhD
American Journal of Kidney Diseases, ISSN 0272-6386, 2015, Volume 65, Issue 3, pp. 484 - 489
C3 glomerulopathy (C3G) is a prototypic complement-mediated kidney disease. Rapidly progressive forms of C3G usually respond poorly to conventional treatments.... 
Nephrology | acute kidney injury (AKI) | rapidly progressing glomerulonephritis | C3 glomerulopathy (C3G) | eculizumab | complement | complement alternative pathway | C5b-9 deposits | MPGN TYPE | HEMOLYTIC-UREMIC SYNDROME | COMPLEMENT ABNORMALITIES | FACTOR-H | DEFICIENT | UROLOGY & NEPHROLOGY | MICE | MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS | DENSE-DEPOSIT DISEASE | Complement C3 - analysis | Complement C3 - metabolism | Humans | Middle Aged | Male | Treatment Outcome | Glomerulonephritis, Membranoproliferative - drug therapy | Antibodies, Monoclonal, Humanized - administration & dosage | Adult | Female | Glomerulonephritis, Membranoproliferative - diagnosis | Infusions, Intravenous | Glomerulonephritis, Membranoproliferative - metabolism | Life Sciences
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text C3 glomerulopathy associated with monoclonal Ig is a distinct subtype
by Ravindran, Aishwarya and Fervenza, Fernando C and Smith, Richard J.H and Sethi, Sanjeev
Kidney International, ISSN 0085-2538, 07/2018, Volume 94, Issue 1, pp. 178 - 186
Monoclonal immunoglobulins (MIg) may play a causal role in C3 glomerulopathy (C3G) by impairing regulation of the alternative pathway of complement.... 
dense deposit disease | monoclonal Ig | C3 glomerulopathy | alternative pathway of complement | C3 glomerulonephritis | MULTIPLE-MYELOMA | CRITERIA | ABNORMALITIES | COMPLEMENT ALTERNATIVE PATHWAY | RISK | GAMMOPATHY | PROLIFERATIVE GLOMERULONEPHRITIS | UNDETERMINED SIGNIFICANCE | UROLOGY & NEPHROLOGY | MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS | Complement C3 - analysis | Age Factors | Follow-Up Studies | Immunoglobulin G - blood | Humans | Middle Aged | Child, Preschool | Male | Glomerulonephritis, Membranoproliferative - blood | Young Adult | Paraproteinemias - pathology | Immunoglobulin G - immunology | Aged, 80 and over | Adult | Female | Child | Antibodies, Monoclonal - immunology | Paraproteinemias - immunology | Glomerulonephritis, Membranoproliferative - pathology | Kidney Glomerulus - pathology | Complement C3 - immunology | Glomerulonephritis, Membranoproliferative - immunology | Biopsy | Complement Pathway, Alternative - immunology | Adolescent | Aged | Paraproteinemias - blood | Kidney Glomerulus - immunology
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text A Healthy Female with C3 Hypocomplementemia and C3 Nephritic Factor
by Egan, Maureen and Sullivan, Kathleen and Frazer-Abel, Ashley and Cunningham-Rundles, Charlotte
Clinical Immunology, ISSN 1521-6616, 2015, Volume 169, pp. 14 - 15
Abstract We present the case of a healthy 16-year-old female with mild myalgias who was found to have a persistently decreased C3 and C3 Nephritic Factor... 
Allergy and Immunology | C3 Nephritic Factor | Complement deficiency | C3 deficiency | IMMUNOLOGY | Complement C3 - analysis | Female | Complement C3 Nephritic Factor - analysis | Complement C3 - deficiency | Humans | Adolescent | Women | Health aspects
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Soluble CR1 therapy improves complement regulation in C3 glomerulopathy
by Zhang, Yuzhou and Nester, Carla M and Holanda, Danniele G and Marsh, Henry C and Hammond, Russell A and Thomas, Lawrence J and Meyer, Nicole C and Hunsicker, Lawrence G and Sethi, Sanjeev and Smith, Richard J.H
Journal of the American Society of Nephrology, ISSN 1046-6673, 11/2013, Volume 24, Issue 11, pp. 1820 - 1829
Dense deposit disease (DDD) and C3 glomerulonephritis (C3GN) are widely recognized subtypes of C3 glomerulopathy. These ultra-rare renal diseases are... 
CELLS | DENSE DEPOSIT DISEASE | ACTIVATION | C3B/C4B RECEPTOR CR-1 | PATHWAY | UROLOGY & NEPHROLOGY | FACTOR-I | H-DEFICIENT MICE | MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS | TYPE-1 | EXPRESSION | Complement C3 - analysis | Glomerulonephritis, Membranoproliferative - drug therapy | Glomerulonephritis, Membranoproliferative - immunology | Animals | Complement Factor H - physiology | Humans | Mice | Complement Pathway, Alternative | Child | Receptors, Complement 3b - therapeutic use | Basic Research
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text Human C3 mutation reveals a mechanism of dense deposit disease pathogenesis and provides insights into complement activation and regulation
by Martínez-Barricarte, Rubén and Heurich, Meike and Valdes-Cañedo, Francisco and Vazquez-Martul, Eduardo and Torreira, Eva and Montes, Tamara and Tortajada, Agustín and Pinto, Sheila and Lopez-Trascasa, Margarita and Morgan, B. Paul and Llorca, Oscar and Harris, Claire L and De Córdoba, Santiago Rodríguez
Journal of Clinical Investigation, ISSN 0021-9738, 10/2010, Volume 120, Issue 10, pp. 3702 - 3712
Dense deposit disease (DDD) is a severe renal disease characterized by accumulation of electron-dense material in the mesangium and glomerular basement... 
HUMAN-FACTOR-H | MEDICINE, RESEARCH & EXPERIMENTAL | HEMOLYTIC-UREMIC SYNDROME | CONVERTASE | ALTERNATIVE PATHWAY | 2 PARTS | MICE | FACTOR-I | MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS | CD46 | DEFICIENCY | Complement C3 - analysis | Complement Activation | Humans | Middle Aged | Male | Complement C3-C5 Convertases - physiology | Glomerulonephritis, Membranoproliferative - genetics | Complement C3b - metabolism | Glomerulonephritis, Membranoproliferative - immunology | Complement Factor H - metabolism | Adult | Female | Mutation | Complement C3 - genetics | Glomerulonephritis, Membranoproliferative - etiology | Gene mutations | Proteases | Proteolysis | Physiological aspects | Genetic aspects | Kidney diseases | Research | Health aspects | Risk factors
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
13. Full Text C3 glomerulonephritis and dense deposit disease share a similar disease course in a large United States cohort of patients with C3 glomerulopathy
by Bomback, Andrew S and Santoriello, Dominick and Avasare, Rupali S and Regunathan-Shenk, Renu and Canetta, Pietro A and Ahn, Wooin and Radhakrishnan, Jai and Marasa, Maddalena and Rosenstiel, Paul E and Herlitz, Leal C and Markowitz, Glen S and D’Agati, Vivette D and Appel, Gerald B
Kidney International, ISSN 0085-2538, 04/2018, Volume 93, Issue 4, pp. 977 - 985
C3 glomerulonephritis (C3GN) and dense deposit disease comprise the two classes of C3 glomerulopathy. Studies from Europe and Asia have aided our understanding... 
dense deposit disease | glomerulonephritis | C3 glomerulopathy | alternative complement pathway | COMPLEMENT ABNORMALITIES | VARIANTS | PATHOLOGY | MPGN | CONSENSUS REPORT | FEATURES | OXFORD CLASSIFICATION | UROLOGY & NEPHROLOGY | IGA NEPHROPATHY | MONOCLONAL GAMMOPATHY | Complement C3 - analysis | United States - epidemiology | Kidney - pathology | Humans | Middle Aged | Kidney - immunology | Male | Atrophy | Renal Insufficiency, Chronic - epidemiology | Young Adult | Time Factors | Kidney Failure, Chronic - pathology | Adult | Female | Retrospective Studies | Complement Pathway, Alternative - genetics | Kidney - physiopathology | Glomerulonephritis, Membranoproliferative - pathology | Kidney Failure, Chronic - immunology | Renal Insufficiency, Chronic - immunology | Risk Factors | Biomarkers - analysis | Treatment Outcome | Glomerulonephritis, Membranoproliferative - therapy | Remission Induction | Disease Progression | Renal Insufficiency, Chronic - pathology | Autoantibodies - immunology | Glomerulonephritis, Membranoproliferative - immunology | Kidney Failure, Chronic - epidemiology | Biopsy | Complement Pathway, Alternative - immunology | Adolescent | Fibrosis | Glomerulonephritis, Membranoproliferative - epidemiology | Glomerulonephritis | End-stage renal disease | Pediatrics | Autoantibodies | Disease | Patients | Glomerular filtration rate | Histopathology | Microscopy | Complement component C3 | Remission | Kidney diseases | Age
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
14. Full Text Mapping interactions between complement C3 and regulators using mutations in atypical hemolytic uremic syndrome
by Schramm, Elizabeth C and Roumenina, Lubka T and Rybkine, Tania and Chauvet, Sophie and Vieira-Martins, Paula and Hue, Christophe and Maga, Tara and Valoti, Elisabetta and Wilson, Valerie and Jokiranta, Sakari and Smith, Richard J. H and Noris, Marina and Goodship, Tim and Atkinson, John P and Fremeaux-Bacchi, Veronique
Blood, ISSN 0006-4971, 04/2015, Volume 125, Issue 15, pp. 2359 - 2369
The pathogenesis of atypical hemolytic uremic syndrome (aHUS) is strongly linked to dysregulation of the alternative pathway of the complement system.... 
DENSE DEPOSIT DISEASE | CONFORMATIONAL-CHANGES | CONVERTASE | FACTOR-B | STRUCTURAL BASIS | FACTOR-H | HEMATOLOGY | MEMBRANE COFACTOR PROTEIN | COMPONENT C3 | CLINICAL PHENOTYPE | BINDING | Complement C3 - analysis | Complement C3 - metabolism | Humans | Models, Molecular | Male | Protein Interaction Maps | Atypical Hemolytic Uremic Syndrome - pathology | Atypical Hemolytic Uremic Syndrome - metabolism | Female | Mutation | Atypical Hemolytic Uremic Syndrome - genetics | Binding Sites | Complement C3 - genetics | Cohort Studies | Immunobiology
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
15. Full Text Redefining C3 glomerulopathy: ‘C3 only’ is a bridge too far
by Larsen, Christopher P and Walker, Patrick D
Kidney International, ISSN 0085-2538, 02/2013, Volume 83, Issue 2, pp. 331 - 332
GLOMERULONEPHRITIS | UROLOGY & NEPHROLOGY | DENSE DEPOSIT DISEASE | COMPLEMENT ABNORMALITIES | Complement C3 - analysis | Complement C3 - metabolism | Humans | Glomerulonephritis - genetics | Male | Complement System Proteins - analysis | Complement System Proteins - metabolism | Glomerulonephritis, Membranoproliferative - genetics | Glomerulonephritis, Membranoproliferative - immunology | Proteomics | Complement System Proteins - genetics | Female | Complement Pathway, Alternative - genetics | Kidney Glomerulus - immunology | Mutation
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights