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PLoS genetics, ISSN 1553-7404, 05/2011, Volume 7, Issue 5, pp. e1002079 - e1002079
Journal Article
Journal Article
American journal of transplantation, ISSN 1600-6135, 03/2013, Volume 13, Issue 3, pp. 663 - 675
.... We retrospectively studied 57 aHUS patients who had received 71 renal transplants. A mutation in complement gene was identified in 39 (68%), in factor H (CFH), factor I (CFI), membrane cofactor‐protein (MCP), C3 and factor B (CFB). At 5 years, death... 
Acute rejection | endothelial cell damage | mutations and polymorphisms in complement alternative pathway | thrombotic microangiopathy | atypical hemolytic and uremic syndrome | renal transplantation | Transplantation | Life Sciences & Biomedicine | Surgery | Science & Technology | Recurrence | Genetic Testing | Prognosis | Humans | Middle Aged | Male | Young Adult | Hemolytic-Uremic Syndrome - genetics | Complement Factor B - genetics | Adult | Complement System Proteins - genetics | Female | Hemolytic-Uremic Syndrome - therapy | Retrospective Studies | Complement C3 - genetics | Biomarkers - metabolism | Risk Factors | Biomarkers - analysis | Kidney Transplantation | Mutation - genetics | Fibrinogen - genetics | Graft Survival - genetics | Adolescent | Membrane Cofactor Protein - genetics | Aged | Complement Factor H - genetics | Graft Rejection - genetics | Atypical Hemolytic Uremic Syndrome | Medical research | Kidneys | Genes | Organ transplant recipients | Medicine, Experimental | Genetic research | Clinical trials | Mutation | Transplants & implants | Drug therapy | Index Medicus | Biological Markers | Complement C3 | Life Sciences | Immunology | Fibrinogen | Hemolytic-Uremic Syndrome | Antigens, CD46 | Graft Survival | Complement Factor H | Complement System Proteins | Complement Factor B | Graft Rejection
Journal Article
PloS one, ISSN 1932-6203, 01/2013, Volume 8, Issue 1, pp. e54339 - e54339
.... The aim of this study was to use the cytoplasmic hybrid (cybrid) model to investigate the molecular and biological functional consequences that occur when comparing the mtDNA H haplogroup (protective for AMD... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Haplotypes | Retinal Pigment Epithelium - metabolism | Epithelial Cells - metabolism | Reactive Oxygen Species - metabolism | Humans | Adenosine Triphosphate - biosynthesis | DNA, Mitochondrial - genetics | Mitochondria - genetics | Myosins - metabolism | Epithelial Cells - cytology | Complement C3 - genetics | Extracellular Matrix Proteins - metabolism | Hybrid Cells - metabolism | Gene Expression | DNA, Mitochondrial - metabolism | Complement C3 - metabolism | Reactive Nitrogen Species - metabolism | Extracellular Matrix Proteins - genetics | Lactic Acid - metabolism | Cells, Cultured | Mitochondria - metabolism | Signal Transduction - genetics | Myosins - genetics | Macular Degeneration - metabolism | Complement Factor H - metabolism | Hybrid Cells - pathology | Macular Degeneration - genetics | Models, Biological | Complement Factor H - genetics | Retinal Pigment Epithelium - cytology | Macular Degeneration - pathology | Macular degeneration | Cellular proteins | Care and treatment | Genetic variation | Development and progression | Genetic aspects | Mitochondrial DNA | Health aspects | Glaucoma | Diabetic retinopathy | Cybrids | Disease | Physicians | Epithelial cells | Genes | Retina | Population studies | Arthritis | Proteins | Signal transduction | Mitochondria | Pathways | Energy | Aging | Age | Deoxyribonucleic acid--DNA | Oxygen | Cell division | Metabolism | Gene expression | Age related diseases | Signaling | Retinal degeneration | Lactic acid | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 5/2005, Volume 102, Issue 20, pp. 7227 - 7232
Journal Article
Journal Article