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1. Full Text Glycerol-3-Phosphate Dehydrogenase 2 Is a Novel Factor H—, Factor H—like Protein 1—, and Plasminogen-Binding Surface Protein of Candida albicans
by Shanshan Luo and Ralf Hoffmann and Christine Skerka and Peter F. Zipfel
The Journal of infectious diseases, ISSN 0022-1899, 2/2013, Volume 207, Issue 4, pp. 594 - 603
Candida albicans | Yeasts | Human umbilical vein endothelial cells | MAJOR ARTICLES AND BRIEF REPORTS | Epithelial cells | Cell walls | Hyphae | Washing | Immune evasion | Regulator genes | Membrane proteins | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Miscellaneous | Infectious diseases | Mycology | Biological and medical sciences | Medical sciences | Cell Line | Complement C3b Inactivator Proteins - metabolism | Glycerolphosphate Dehydrogenase - metabolism | Complement Factor H - metabolism | Epithelial Cells - metabolism | Endothelial Cells - metabolism | U937 Cells | Humans | Plasminogen - metabolism | Membrane Proteins - metabolism | Fungal Proteins - metabolism | Sugar esters | Complement factor H | Genetic aspects | Research | Oxidoreductases | Binding proteins | Index Medicus | Abridged Index Medicus
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2. Full Text Complement factor H binds malondialdehyde epitopes and protects from oxidative stress
by Weismann, David and Hartvigsen, Karsten and Lauer, Nadine and Bennett, Keiryn L and Scholl, Hendrik P. N and Issa, Peter Charbel and Cano, Marisol and Brandstätter, Hubert and Tsimikas, Sotirios and Skerka, Christine and Superti-Furga, Giulio and Handa, James T and Zipfel, Peter F and Witztum, Joseph L and Binder, Christoph J
Nature (London), ISSN 0028-0836, 10/2011, Volume 478, Issue 7367, pp. 76 - 81
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Dyskeratosis | Biological and medical sciences | Medical sciences | Dermatology | Inflammation - pathology | Protein Binding - genetics | Retina - metabolism | Epitopes - metabolism | Oxidative Stress | Humans | Malondialdehyde - chemistry | Complement System Proteins - immunology | Male | Complement System Proteins - metabolism | Necrosis | Inflammation - metabolism | Female | Malondialdehyde - metabolism | Protein Structure, Tertiary | Complement Factor H - immunology | Complement Inactivator Proteins - metabolism | Enzyme-Linked Immunosorbent Assay | Mice, Inbred C57BL | Complement Inactivator Proteins - immunology | Inflammation - immunology | Binding Sites - genetics | Mutation - genetics | Macular Degeneration - metabolism | Animals | Complement Factor H - metabolism | Malondialdehyde - immunology | Epitopes - chemistry | Mice | Complement Factor H - genetics | Lipid Peroxidation | Macrophages, Peritoneal - metabolism | Malondialdehyde - antagonists & inhibitors | Apoptosis | Complement Inactivator Proteins - genetics | Macular Degeneration - pathology | Macular degeneration | Oxidative stress | Complement factor H | Care and treatment | Physiological aspects | Research | Health aspects | Risk factors | Proteins | Flow cytometry | Plasma | Pathogenesis | Low density lipoprotein | Mass spectrometry | Molecular weight | Binding sites | Index Medicus
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3. Full Text Streptococcus pneumoniae Capsular Serotype Invasiveness Correlates with the Degree of Factor H Binding and Opsonization with C3b/iC3b
by Catherine Hyams and Krzysztof Trzcinski and Emilie Camberlein and Daniel M. Weinberger and Suneeta Chimalapati and Mahdad Noursadeghi and Marc Lipsitch and Jeremy S. Brown
Infection and Immunity, ISSN 0019-9567, 01/2013, Volume 81, Issue 1, pp. 354 - 363
Infectious Diseases | Immunology | Life Sciences & Biomedicine | Science & Technology | Pneumococcal Infections - metabolism | Bacterial Capsules - metabolism | Humans | Mutation - immunology | Serotyping - methods | Streptococcus pneumoniae - immunology | Complement C3b - metabolism | Pneumococcal Infections - immunology | Streptococcus pneumoniae - isolation & purification | Streptococcus pneumoniae - pathogenicity | Streptococcus pneumoniae - metabolism | Adult | Pneumococcal Infections - microbiology | Bacterial Proteins - immunology | Antibodies, Bacterial - metabolism | Child | Neutrophils - metabolism | Complement Factor H - immunology | Complement C3 - metabolism | Neutrophils - immunology | Protein Binding - immunology | Complement C3 - immunology | Complement Factor H - metabolism | Antibodies, Bacterial - immunology | Bacterial Proteins - metabolism | Bacterial Capsules - immunology | Complement C3b - immunology | Index Medicus | Bacterial Infections
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4. Full Text Factor H-related protein 1 (CFHR-1) inhibits complement C5 convertase activity and terminal complex formation
by Heinen, Stefan and Hartmann, Andrea and Lauer, Nadine and Wiehl, Ulrike and Dahse, Hans-Martin and Schirmer, Sylvia and Gropp, Katharina and Enghardt, Tina and Wallich, Reinhard and Hälbich, Steffi and Mihlan, Michael and Schlötzer-Schrehardt, Ursula and Zipfel, Peter F and Skerka, Christine
Blood, ISSN 0006-4971, 2009, Volume 114, Issue 12, pp. 2439 - 2447
Life Sciences & Biomedicine | Hematology | Science & Technology | Hematologic and hematopoietic diseases | Biological and medical sciences | Medical sciences | Endothelium, Vascular - cytology | Retina - metabolism | Immunoprecipitation | Complement Membrane Attack Complex - metabolism | Humans | Immunoenzyme Techniques | Complement C3d - metabolism | Complement C3b - metabolism | Kidney - metabolism | Flow Cytometry | Retina - cytology | Umbilical Veins - cytology | Complement C3-C5 Convertases - metabolism | Enzyme-Linked Immunosorbent Assay | Cells, Cultured | Kidney - cytology | Complement C3-C5 Convertases - antagonists & inhibitors | Complement C3b Inactivator Proteins - physiology | Microscopy, Confocal | Animals | Complement Factor H - metabolism | Endothelium, Vascular - metabolism | Erythrocytes - metabolism | Fluorescent Antibody Technique | Sheep | Umbilical Veins - metabolism | Index Medicus | Abridged Index Medicus
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5. Full Text Identification of factor h-like protein 1 as the predominant complement regulator in Bruch's Membrane: Implications for age-related macular degeneration
by Clark, Simon J and Schmidt, Christoph Q and White, Anne M and Hakobyan, Svetlana and Morgan, B. Paul and Bishop, Paul N
The Journal of immunology (1950), ISSN 0022-1767, 11/2014, Volume 193, Issue 10, pp. 4962 - 4970
Life Sciences & Biomedicine | Immunology | Science & Technology | Heparitin Sulfate - immunology | Retina - metabolism | Retinal Drusen - genetics | Complement Activation | Macular Degeneration - immunology | Retinal Drusen - metabolism | Bruch Membrane - pathology | Humans | Extracellular Matrix - immunology | Complement C3b Inactivator Proteins - genetics | Extracellular Matrix - metabolism | Homeostasis | Retina - immunology | Heparitin Sulfate - metabolism | Complement C3b Inactivator Proteins - metabolism | Bruch Membrane - immunology | Retinal Drusen - immunology | Complement Factor H - immunology | Signal Transduction | Retinal Drusen - pathology | Gene Expression Regulation | Glycosylation | Immunity, Innate | Protein Transport | Macular Degeneration - metabolism | Complement Factor H - metabolism | Macular Degeneration - genetics | Protein Binding | Complement Factor H - genetics | Bruch Membrane - metabolism | Extracellular Matrix - pathology | Retina - pathology | Complement C3b Inactivator Proteins - immunology | Macular Degeneration - pathology | Index Medicus | Abridged Index Medicus
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6. Full Text Human Complement Factor H Is a Reductase for Large Soluble von Willebrand Factor Multimers—Brief Report
by Nolasco, Leticia and Nolasco, Jennifer and Feng, Shuju and Afshar-Kharghan, Vahid and Moake, Joel
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 11/2013, Volume 33, Issue 11, pp. 2524 - 2528
oxidoreductases | von Willebrand factor | complement factor H | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Sulfhydryl Compounds - metabolism | Complement Factor H - metabolism | Molecular Weight | Oxidoreductases - metabolism | Endothelium, Vascular - metabolism | Humans | von Willebrand Factor - chemistry | Solubility | Enzyme Activation - physiology | von Willebrand Factor - metabolism | Index Medicus
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7. Full Text Disease-linked mutations in factor H reveal pivotal role of cofactor activity in Self-surface–selective regulation of complement activation
by Kerr, Heather and Wong, Edwin and Makou, Elisavet and Yang, Yi and Marchbank, Kevin and Kavanagh, David and Richards, Anna and Herbert, Andrew P and Barlow, Paul N
The Journal of biological chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 32, pp. 13345 - 13360
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Complement C3d - genetics | Complement Factor I - chemistry | Complement Activation | Sheep, Domestic | Humans | Bacterial Proteins - chemistry | Erythrocytes - chemistry | Recombinant Fusion Proteins - metabolism | Complement C3d - metabolism | Streptococcus pneumoniae - metabolism | Surface Properties | Complement C3d - chemistry | Protein Interaction Domains and Motifs | Atypical Hemolytic Uremic Syndrome - genetics | Binding Sites | Peptide Fragments - genetics | Hemolysis | Peptide Fragments - metabolism | Complement C3 Convertase, Alternative Pathway - chemistry | Immobilized Proteins - chemistry | Complement C3 Convertase, Alternative Pathway - metabolism | Immobilized Proteins - genetics | Bacterial Proteins - genetics | Solubility | Complement Factor I - genetics | Recombinant Fusion Proteins - chemistry | Macular Degeneration - metabolism | Peptide Fragments - chemistry | Animals | Complement Factor H - metabolism | Macular Degeneration - genetics | Atypical Hemolytic Uremic Syndrome - metabolism | Immobilized Proteins - metabolism | Bacterial Proteins - metabolism | Mutation | Complement Factor H - genetics | Complement Factor I - metabolism | Complement C3 Convertase, Alternative Pathway - genetics | Amino Acid Substitution | Complement Factor H - chemistry | Index Medicus | kidney | Immunology | Streptococcus | innate immunity | complement system | recombinant protein expression | surface plasmon resonance (SPR) | multiple domain | mutagenesis | CCP module | erythrocyte
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8. Full Text Complement factor H related proteins (CFHRs)
by Skerka, Christine and Chen, Qian and Fremeaux-Bacchi, Veronique and Roumenina, Lubka T
Molecular immunology, ISSN 0161-5890, 12/2013, Volume 56, Issue 3, pp. 170 - 180
Biochemistry & Molecular Biology | Immunology | Life Sciences & Biomedicine | Science & Technology | Complement Factor H - immunology | Multigene Family | Macular Degeneration - immunology | Apolipoproteins - metabolism | Humans | Complement C3b Inactivator Proteins - genetics | Complement System Proteins - immunology | Apolipoproteins - immunology | Hemolytic-Uremic Syndrome - immunology | Complement System Proteins - metabolism | Complement C3b Inactivator Proteins - metabolism | Glomerulonephritis, Membranoproliferative - genetics | Hemolytic-Uremic Syndrome - genetics | Glomerulonephritis, Membranoproliferative - immunology | Complement Factor H - metabolism | Macular Degeneration - genetics | Apolipoproteins - genetics | Complement Factor H - genetics | Complement C3b Inactivator Proteins - immunology | Macular degeneration | Proteins | Systemic lupus erythematosus | Immunoglobulin A | Index Medicus
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9. Full Text The meningococcal vaccine candidate GNA1870 binds the complement regulatory protein factor H and enhances serum resistance
by Madico, Guillermo and Welsch, Jo Anne and Lewis, Lisa A and McNaughton, Anne and Perlman, David H and Costello, Catherine E and Ngampasutadol, Jutamas and Vogel, Ulrich and Granoff, Dan M and Ram, Sanjay
The Journal of immunology (1950), ISSN 0022-1767, 07/2006, Volume 177, Issue 1, pp. 501 - 510
Life Sciences & Biomedicine | Immunology | Science & Technology | Complement Factor H - antagonists & inhibitors | Vaccines, DNA - genetics | Neisseria meningitidis - metabolism | Humans | Antigens, Bacterial - immunology | Porins - metabolism | Vaccines, DNA - immunology | Molecular Sequence Data | Antigens, Bacterial - genetics | Blood Bactericidal Activity - genetics | Genetic Variation | Neisseria meningitidis - immunology | Gene Deletion | Adjuvants, Immunologic - metabolism | Adjuvants, Immunologic - genetics | Adult | Neisseria meningitidis - genetics | Bacterial Proteins - immunology | Complement Pathway, Alternative - genetics | Binding, Competitive - immunology | Amino Acid Sequence | Complement Factor H - immunology | Meningococcal Vaccines - genetics | Bacterial Adhesion - immunology | Meningococcal Vaccines - metabolism | Bacterial Proteins - genetics | Blood Bactericidal Activity - immunology | Complement Factor H - metabolism | Bacterial Outer Membrane Proteins - metabolism | Complement Pathway, Alternative - immunology | Bacterial Proteins - metabolism | Ligands | Antibodies, Monoclonal - metabolism | Meningococcal Vaccines - immunology | Binding Sites, Antibody | Vaccines, DNA - metabolism | Antigens, Bacterial - metabolism | Index Medicus | Abridged Index Medicus
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