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by Doria-Rose, Nicole A and Schramm, Chaim A and Gorman, Jason and Moore, Penny L and Bhiman, Jinal N and Dekosky, Brandon J and Ernandes, Michael J and Georgiev, Ivelin S and Kim, Helen J and Pancera, Marie and Staupe, Ryan P and Altae-Tran, Han R and Bailer, Robert T and Crooks, Ema T and Cupo, Albert and z, Aliaksan and Garrett, Nigel J and Hoi, Kam H and Kong, Rui and Louder, Mark K and Longo, Nancy S and McKee, Krisha and Nonyane, Molati and O'Dell, Sijy and Roark, Ryan S and Rudicell, Rebecca S and Schmidt, Stephen D and Sheward, Daniel J and Soto, Cinque and Wibmer, Constantinos Kurt and Yang, Yongping and Zhang, Zhenhai and Mullikin, James C and Binley, James M and Sanders, Rogier W and Wilson, Ian A and Moore, John P and Ward, Anew B and Georgiou, George and Williamson, Carolyn and Abdool Karim, Salim S and Morris, Lynn and Kwong, Peter D and Shapiro, Lawrence and Mascola, John R and Becker, Jesse and Benjamin, Betty and Blakesley, Robert and Bouffard, Gerry and Brooks, Shelise and Coleman, Holly and Dekhtyar, Mila and Gregory, Michael and Guan, Xiaobin and Gupta, Jyoti and Han, Joel and Hargrove, April and Ho, Shi-ling and Johnson, Taccara and Legaspi, Richelle and Lovett, Sean and Maduro, Quino and Masiello, Cathy and Maskeri, Baishali and McDowell, Jenny and Montemayor, Casana and Mullikin, James and Park, Morgan and Riebow, Nancy and Schandler, Karen and Schmidt, Brian and Sison, Christina and Stantripop, Mal and Thomas, James and Thomas, Pam and Vemulapalli, Meg and Young, Alice and NISC Comparative Sequencing and NISC Comparative Sequencing Program
Nature, ISSN 0028-0836, 2014, Volume 509, Issue 7498, pp. 55 - 62
Antibodies capable of neutralizing HIV-1 often target variable regions 1 and 2 (V1V2) of the HIV-1 envelope, but the mechanism of their elicitation has been... 
B-CELLS | MAXIMUM-LIKELIHOOD | STRUCTURAL BASIS | HIV-1-NEUTRALIZING ANTIBODIES | MULTIDISCIPLINARY SCIENCES | IMMUNODEFICIENCY-VIRUS TYPE-1 | VACCINE EFFICACY | INFECTION | BROAD | HUMAN MONOCLONAL-ANTIBODIES | ENVELOPE TRIMER | Complementarity Determining Regions - genetics | Epitope Mapping | Epitopes, B-Lymphocyte - chemistry | Humans | AIDS Vaccines - immunology | Molecular Sequence Data | Antibody Affinity - immunology | Neutralization Tests | Epitopes, B-Lymphocyte - immunology | HIV Antibodies - isolation & purification | HIV Infections - immunology | Antibodies, Neutralizing - immunology | HIV Antibodies - immunology | HIV Envelope Protein gp160 - chemistry | Complementarity Determining Regions - chemistry | HIV-1 - chemistry | Binding Sites - immunology | B-Lymphocytes - metabolism | Protein Structure, Tertiary | Amino Acid Sequence | CD4 Antigens - immunology | B-Lymphocytes - cytology | Models, Molecular | Antibody Affinity - genetics | Antibodies, Neutralizing - genetics | HIV Antibodies - chemistry | AIDS Vaccines - chemistry | Antibodies, Neutralizing - isolation & purification | Cell Lineage | HIV-1 - immunology | B-Lymphocytes - immunology | Antibodies, Neutralizing - chemistry | Complementarity Determining Regions - immunology | HIV Envelope Protein gp160 - immunology | HIV Antibodies - genetics | Somatic Hypermutation, Immunoglobulin - genetics | CD4 Antigens - metabolism | Evolution, Molecular | Viral antibodies | Antigen-antibody reactions | AIDS vaccines | AIDS (Disease) | Antibodies | Physiological aspects | Research | AIDS research | Cell culture | Genes | Human immunodeficiency virus--HIV | Phylogenetics | Amino acids | Infections | Genomes | Mutation | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 09/2012, Volume 489, Issue 7417, pp. 526 - 532
Immune recognition of protein antigens relies on the combined interaction of multiple antibody loops, which provide a fairly large footprint and constrain the... 
HIV-1 | SYSTEM | POTENT NEUTRALIZATION | EPITOPE | HEMAGGLUTININ | RECOGNITION | STRUCTURAL BASIS | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | BINDING-SITE | BROAD | Influenza A Virus, H1N1 Subtype - immunology | Orthomyxoviridae Infections - prevention & control | Complementarity Determining Regions - genetics | Influenza A virus - chemistry | Cross Reactions - genetics | Molecular Sequence Data | Crystallography, X-Ray | Antibody Specificity - genetics | Hemagglutinin Glycoproteins, Influenza Virus - immunology | Epitopes - immunology | Antibodies, Neutralizing - immunology | Antibody Specificity - immunology | Complementarity Determining Regions - chemistry | Conserved Sequence | Influenza A virus - immunology | Binding Sites | Hemagglutinin Glycoproteins, Influenza Virus - chemistry | Enzyme-Linked Immunosorbent Assay | Models, Molecular | Antigens, Viral - chemistry | Antibodies, Neutralizing - genetics | Cross Reactions - immunology | Influenza A Virus, H3N2 Subtype - immunology | Mutation - genetics | Antigens, Viral - immunology | Animals | Influenza A Virus, H3N2 Subtype - chemistry | Influenza Vaccines - immunology | Antibodies, Neutralizing - chemistry | Antibodies, Viral - chemistry | Complementarity Determining Regions - immunology | Antibodies, Viral - immunology | Protein Conformation | Epitopes - chemistry | Influenza A Virus, H1N1 Subtype - chemistry | Mice | Influenza A virus - classification | Orthomyxoviridae Infections - virology | Antibodies, Viral - genetics | Orthomyxoviridae Infections - immunology | Influenza viruses | Agglutinins | Viruses | Complementarity-determining regions | Research | Observations | Inactivation | Proteins | Infections | Binding sites | Index Medicus
Journal Article
Nature Genetics, ISSN 1061-4036, 07/2016, Volume 48, Issue 7, pp. 725 - 732
Journal Article
Nature, ISSN 0028-0836, 12/2014, Volume 516, Issue 7531, pp. 418 - 422
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 02/2013, Volume 425, Issue 4, pp. 803 - 811
Journal Article
Journal of Immunology, ISSN 0022-1767, 09/2012, Volume 189, Issue 6, pp. 3221 - 3230
Journal Article
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2011, Volume 128, Issue 6, pp. 1266 - 1276.e11
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 12/2013, Volume 110, Issue 51, pp. E4997 - E5005
Human cytomegalovirus (HCMV) can cause serious morbidity/ mortality in transplant patients, and congenital HCMV infection can lead to birth defects. Developing... 
Antiviral antibody | Monoclonal antibody | NATURAL INFECTION | VIRUS-INFECTION | LINKED-IMMUNOSORBENT-ASSAY | MULTIDISCIPLINARY SCIENCES | PRIMARY INFECTION | SMOOTH-MUSCLE | ORGAN TRANSPLANT RECIPIENTS | CMV-HYPERIMMUNE GLOBULIN | antiviral antibody | EPITHELIAL-CELLS | ENDOTHELIAL-CELLS | monoclonal antibody | ANTIBODY-RESPONSE | Complementarity Determining Regions - genetics | Humans | Multiprotein Complexes - genetics | Cytomegalovirus Infections - immunology | Cytomegalovirus Infections - genetics | Immunoglobulin Light Chains - genetics | Antibodies, Neutralizing - immunology | Cytomegalovirus Infections - prevention & control | Female | Membrane Glycoproteins - immunology | Immunoglobulin Heavy Chains - immunology | Antibodies, Monoclonal - immunology | Cytomegalovirus Vaccines - genetics | Immunoglobulin Light Chains - immunology | Cytomegalovirus - genetics | Rabbits | Viral Envelope Proteins - genetics | Antibodies, Neutralizing - genetics | Membrane Glycoproteins - genetics | Antibodies, Monoclonal - genetics | Cytomegalovirus - immunology | Animals | Complementarity Determining Regions - immunology | Antibodies, Viral - immunology | Viral Envelope Proteins - immunology | Cytomegalovirus Vaccines - immunology | Antibodies, Viral - genetics | Immunoglobulin Heavy Chains - genetics | Multiprotein Complexes - immunology | Antigens | Immunology | Monoclonal antibodies | Viruses | Glycoproteins | Vaccines | Gene expression | Index Medicus | Biological Sciences | PNAS Plus
Journal Article