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1. Full Text Lonicera japonica Thunb.: Ethnopharmacology, phytochemistry and pharmacology of an important traditional Chinese medicine
by Shang, Xiaofei and Pan, Hu and Li, Maoxing and Miao, Xiaolou and Ding, Hong
Journal of ethnopharmacology, ISSN 0378-8741, 10/2011, Volume 138, Issue 1, pp. 1 - 21
Ethnopharmacology | Chlorogenic acid | Anti-inflammatory | Antiviral activity | Lonicera japonica | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Integrative & Complementary Medicine | Plant Sciences | Science & Technology | Biological and medical sciences | Pharmacognosy. Homeopathy. Health food | Medical sciences | General pharmacology | Pharmacology. Drug treatments | Plant Extracts - chemistry | Lonicera - chemistry | Medicine, Chinese Traditional | Plant Extracts - pharmacology | Humans | Phytotherapy | Plant Extracts - therapeutic use | Carrageenin | Avian influenza viruses | Esters | Aspartate | Superoxide | Liquid chromatography | Medicine, Chinese | Acyclovir | HIV (Viruses) | Photochemotherapy | Fatty acids | Avian influenza | Antioxidants | Phytochemistry | Nitric oxide | Detectors | Methylation | Health aspects | Mitogens | Mass spectrometry | Cancer | Index Medicus | EtOAc, ethyl acetate | LED, Least Effective Dose | ACV, acyclovir | DAD, diode-array detection | TLC, thin layer chromatography | IC50, 50% inhibition concentration | MPO, myeloperoxidase | CGN, carrageenan | HPLC, high performance liquid chromatography | Cd, cadmium | CAT, catalase | PMNs, polymorphonuclear leukocytes | TEAC, Trolox equivalent antioxidant capacity | HDL-C, high density lipoprotein cholesterin | PUFA, polyunsaturated fatty acid | DPPH, 1,1-diphenyl-2-picrylhydrazyl | MIC, minimum inhibitory concentration | CPE, cytopathologic effect | MUFA, monounsaturated fatty acid | NDV, newcastle disease virus | ELSD, evaporative light scattering detectors | MEC, minimum effective concentration | MeOH, methyl alcohol | TCM, traditional Chinese medicine | SARS coronavirus, severe acute respiratory syndromes coronavirus | HSV, Herpes simplex virus | LPS, lipopolysaccharide | COX, cycloxygenase | JNK, Jun nuclear kinase | MTT, methyl thiazolyl tetrazolium | MAPK, mitogen activated protein kinase | AIV, avian influenza virus | GSH, glutathione | SI, selectivity index | Lonicera japonica, Lonicera japonica Thunb | NO, nitric oxide | AST, aspartate amino transferase | PDT, photodynamic therapy | ROS, reactive oxygen species | PAPR2, proteinase-activated receptor 2 | TI, therapeutic index | SFA, saturated fatty acid | SOD, superoxide dismutase | TNF-α, tumor necrosis factor-α | ERK, extracellular signal-regulated kinase | HUVEC, Human Umbilical Vein Endothelial Cells | MDA, malondialdehyde | GC–MS, gas chromatography–mass spectrometry | ConA, concanavalin A | TOF-MS, time-of-flight mass spectrometry | HIV-1, human immunodeficiency virus-1 | ALT, alanine transarninase | RSV, respiratory syncytial virus
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2. Full Text Sibiriline, a new small chemical inhibitor of receptor‐interacting protein kinase 1, prevents immune‐dependent hepatitis
by Le Cann, Fabienne and Delehouzé, Claire and Leverrier‐Penna, Sabrina and Filliol, Aveline and Comte, Arnaud and Delalande, Olivier and Desban, Nathalie and Baratte, Blandine and Gallais, Isabelle and Piquet‐Pellorce, Claire and Faurez, Florence and Bonnet, Marion and Mettey, Yvette and Goekjian, Peter and Samson, Michel and Vandenabeele, Peter and Bach, Stéphane and Dimanche‐Boitrel, Marie‐Thérèse
The FEBS journal, ISSN 1742-464X, 09/2017, Volume 284, Issue 18, pp. 3050 - 3068
kinase inhibitor | Concanavalin A ‐induced hepatitis | molecular docking | necroptosis | RIPK1 inhibitor | Concanavalin A -induced hepatitis | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Apoptosis - drug effects | Hepatitis, Animal - prevention & control | Humans | Caspase 3 - immunology | Apoptosis - genetics | Hepatitis, Animal - genetics | Male | Necrosis - immunology | Protein Kinase Inhibitors - chemistry | TNF-Related Apoptosis-Inducing Ligand - pharmacology | Caspase 3 - genetics | Indoles - pharmacology | Receptor-Interacting Protein Serine-Threonine Kinases - immunology | Hepatitis, Animal - chemically induced | Spiro Compounds - chemistry | Fibroblasts - metabolism | Immunologic Factors - chemistry | Alkaloids - pharmacology | Signal Transduction | Jurkat Cells | Hepatitis, Animal - immunology | Gene Expression Regulation | Imidazoles - pharmacology | Concanavalin A | Cycloheximide - pharmacology | Necrosis - chemically induced | HT29 Cells | Tumor Necrosis Factor-alpha - pharmacology | Receptor-Interacting Protein Serine-Threonine Kinases - genetics | Animals | Fibroblasts - drug effects | Fibroblasts - cytology | Mice | Molecular Docking Simulation | Necrosis - genetics | Protein Kinase Inhibitors - pharmacology | Receptor-Interacting Protein Serine-Threonine Kinases - antagonists & inhibitors | Alkaloids - chemistry | Cell Line, Transformed | Immunologic Factors - pharmacology | Spiro Compounds - pharmacology | Prevention | Hepatitis | Cell death | Analysis | Liver | Mitogens | Protein kinases | Competition | Animal models | Serine | Hydrophobicity | Kinases | Molecular docking | Proteins | FADD protein | Fas-associated protein | Tumor necrosis factor-TNF | Libraries | Adenosine triphosphate | Liver diseases | Threonine | Mortality | Caspase | Inhibitors | Protein kinase | Tumor necrosis factor | ATP | Binding sites | Apoptosis | Index Medicus | Life Sciences | Genetics
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3. Full Text Estrogen modulates in vitro T cell responses in a concentration- and receptor-dependent manner: Effects on intracellular molecular targets and antioxidant enzymes
by Priyanka, Hannah P and Krishnan, Harini C and Singh, Ran Vijay and Hima, Lalgi and ThyagaRajan, Srinivasan
Molecular immunology, ISSN 0161-5890, 12/2013, Volume 56, Issue 4, pp. 328 - 339
Estrogen receptor | CREB | Nitric oxide | Cytokine | 17β-Estradiol | Akt | ERK | Biochemistry & Molecular Biology | Immunology | Life Sciences & Biomedicine | Science & Technology | Propionates - pharmacology | Estradiol - analogs & derivatives | Estrogens - pharmacology | Nitriles - pharmacology | Concanavalin A - pharmacology | Antioxidants - metabolism | Estrogen Antagonists - pharmacology | Dose-Response Relationship, Drug | Estrogen Receptor beta - metabolism | Intracellular Space - enzymology | Estrogen Receptor alpha - agonists | Estrogen Receptor beta - agonists | T-Lymphocytes - metabolism | T-Lymphocytes - drug effects | Estrogen Receptor alpha - metabolism | Estrogen Receptor beta - antagonists & inhibitors | Estradiol - pharmacology | Superoxide Dismutase - metabolism | Phenols - pharmacology | Pyrazoles - pharmacology | Glutathione Peroxidase - metabolism | Intracellular Space - drug effects | Cytokines - metabolism | Cells, Cultured | Rats | Estrogen Receptor alpha - antagonists & inhibitors | Spleen - cytology | Rats, Sprague-Dawley | Catalase - metabolism | Animals | Tamoxifen - pharmacology | Cell Proliferation - drug effects | Nitric Oxide - metabolism | Antioxidants | Phenols | Enzymes | T cells | Estrogen | Index Medicus
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4. Full Text Nitric oxide plays a critical role in suppression of T-cell proliferation by mesenchymal stem cells
by Sato, Kazuya and Ozaki, Katsutoshi and Oh, Iekuni and Meguro, Akiko and Hatanaka, Keiko and Nagai, Tadashi and Muroi, Kazuo and Ozawa, Keiya
Blood, ISSN 0006-4971, 01/2007, Volume 109, Issue 1, pp. 228 - 234
Life Sciences & Biomedicine | Hematology | Science & Technology | Fundamental and applied biological sciences. Psychology | Fundamental immunology | Biological and medical sciences | Immunobiology | Modulation of the immune response (stimulation, suppression) | CD8-Positive T-Lymphocytes - cytology | Dinoprostone - physiology | Humans | B-Lymphocyte Subsets - cytology | T-Lymphocyte Subsets - drug effects | CD8-Positive T-Lymphocytes - metabolism | Phosphorylation - drug effects | Macrophages - physiology | B-Lymphocyte Subsets - drug effects | Nitric Oxide - biosynthesis | Signal Transduction | CD4-Positive T-Lymphocytes - metabolism | Cell Division - drug effects | Receptors, Antigen, T-Cell - physiology | Mice, Knockout | B-Lymphocyte Subsets - metabolism | Mice | Tryptophan - pharmacology | HeLa Cells | Interleukin-2 - biosynthesis | Indoleamine-Pyrrole 2,3,-Dioxygenase - physiology | Nitric Oxide Synthase Type II - metabolism | Tetradecanoylphorbol Acetate - pharmacology | T-Lymphocyte Subsets - cytology | Concanavalin A - pharmacology | Nitric Oxide - pharmacology | STAT5 Transcription Factor - metabolism | Protein Processing, Post-Translational - drug effects | Nitric Oxide Synthase Type II - antagonists & inhibitors | Tryptophan - analogs & derivatives | Enzyme Induction - drug effects | Transforming Growth Factor beta - antagonists & inhibitors | Mesenchymal Stromal Cells - physiology | NG-Nitroarginine Methyl Ester - pharmacology | Transforming Growth Factor beta - immunology | Cell Line | Antigens, CD19 - analysis | CD4-Positive T-Lymphocytes - cytology | Mice, Inbred C57BL | Nitric Oxide Synthase Type II - deficiency | Nitric Oxide - physiology | Cyclooxygenase Inhibitors - pharmacology | Animals | Lymphocyte Activation - drug effects | CD8-Positive T-Lymphocytes - drug effects | Ionomycin - pharmacology | CD4-Positive T-Lymphocytes - drug effects | Indoleamine-Pyrrole 2,3,-Dioxygenase - antagonists & inhibitors | Interferon-gamma - biosynthesis | Prostaglandin-Endoperoxide Synthases - physiology | Index Medicus | Abridged Index Medicus
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5. Full Text Role of the sodium-dependent phosphate co-transporters and of the phosphate complexes of uranyl in the cytotoxicity of uranium in LLC-PK1 cells
by Muller, D and Houpert, P and Cambar, J and Hengé-Napoli, M-H
Toxicology and applied pharmacology, ISSN 0041-008X, 07/2006, Volume 214, Issue 2, pp. 166 - 177
Sodium-dependent phosphate co-transport | Uranium | NaPi | Cytotoxicity | LLC-PK | MDCK | Uranyl | Speciation | Pharmacology & Pharmacy | Toxicology | Life Sciences & Biomedicine | Science & Technology | Biological and medical sciences | Medical sciences | Colchicine - pharmacology | Tetradecanoylphorbol Acetate - pharmacology | Foscarnet - pharmacology | Concanavalin A - pharmacology | Maleimides - pharmacology | Carbonates - pharmacology | Cytochalasin D - pharmacology | Tetradecanoylphorbol Acetate - antagonists & inhibitors | Sodium-Phosphate Cotransporter Proteins, Type IIa - metabolism | Dose-Response Relationship, Drug | LLC-PK1 Cells | Uranium - toxicity | Dexamethasone - pharmacology | Swine | Computer Simulation | Indoles - pharmacology | Sodium-Phosphate Cotransporter Proteins, Type IIb - physiology | Phosphates - pharmacology | Cell Survival - drug effects | Kidney Tubules, Proximal - cytology | Cadmium - toxicity | Phosphates - physiology | Meglumine - analogs & derivatives | Calcium Chloride - pharmacology | Animals | Meglumine - pharmacology | Uranium Compounds | Phosphates - antagonists & inhibitors | Kidney Tubules, Proximal - metabolism | Kidney Tubules, Proximal - drug effects | Index Medicus
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6. Full Text Spontaneous synchronized calcium oscillations in neocortical neurons in the presence of physiological [Mg 2+]: involvement of AMPA/kainate and metabotropic glutamate receptors
by Dravid, Shashank M and Murray, Thomas F
Brain research, ISSN 0006-8993, 2004, Volume 1006, Issue 1, pp. 8 - 17
Calcium oscillation | AMPA receptor | Magnesium | NMDA receptor | Neocortical neuron | Metabotropic glutamate receptor | Excitatory amino acid receptors: physiology, pharmacology and modulation | Neurotransmitters, modulators, transporters and receptors | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Vertebrates: nervous system and sense organs | Biological and medical sciences | Biochemistry and metabolism | Central nervous system | Antihypertensive Agents - pharmacology | Receptors, Glutamate - classification | Aniline Compounds - metabolism | Concanavalin A - pharmacology | Embryo, Mammalian | Calcium Signaling - physiology | Anesthetics, Local - pharmacology | Dose-Response Relationship, Drug | Xanthenes - metabolism | Magnesium - physiology | Neurons - metabolism | Tetrodotoxin - pharmacology | Nifedipine - pharmacology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Excitatory Amino Acid Agonists - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Calcium Channel Blockers - pharmacology | Benzothiadiazines - pharmacology | Veratridine - pharmacology | Animals | Calcium Signaling - drug effects | Thapsigargin - pharmacology | Neocortex - cytology | Mice | Receptors, Glutamate - physiology | Index Medicus
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7. Full Text Transcription profiles of LPS-stimulated THP-1 monocytes and macrophages: a tool to study inflammation modulating effects of food-derived compounds
by Chanput, Wasaporn and Mes, Jurriaan and Vreeburg, Robert A. M and Savelkoul, Huub F. J and Wichers, Harry J
Food & function, ISSN 2042-6496, 11/2010, Volume 1, Issue 3, pp. 254 - 261
Food Science & Technology | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Mitogens - pharmacology | Concanavalin A - pharmacology | Monocytes - cytology | Humans | Citrus - chemistry | Gene Expression Profiling | Hordeum - chemistry | Nitric Oxide Synthase Type II - immunology | Cyclooxygenase 2 - genetics | Monocytes - physiology | Transcription Factors - immunology | Cyclooxygenase 2 - immunology | Cytokines - genetics | Cytokines - immunology | Macrophages - physiology | Glucans - pharmacology | Macrophages - cytology | Transcription Factors - genetics | Monocytes - drug effects | Pectins - pharmacology | Nitric Oxide Synthase Type II - genetics | Quercetin - pharmacology | Lipopolysaccharides - pharmacology | Cell Line, Tumor | Macrophages - drug effects | Immunologic Factors - pharmacology | Index Medicus
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8. Full Text Validation of immunological biomarkers for the pharmacodynamic monitoring of immunosuppressive drugs in humans
by Böhler, Torsten and Nolting, Jochen and Kamar, Nassim and Gurragchaa, Purevtseren and Reisener, Kathrin and Glander, Petra and Neumayer, Hans-H and Budde, Klemens and Klupp, Jochen
Therapeutic drug monitoring, ISSN 0163-4356, 02/2007, Volume 29, Issue 1, pp. 77 - 86
Clinical trials | Biomarker | Immunosuppression | Pharmacodynamics | Transplantation | Pharmacology & Pharmacy | Toxicology | Life Sciences & Biomedicine | Medical Laboratory Technology | Science & Technology | Biological and medical sciences | Pharmacology. Drug treatments | Medical sciences | Tetradecanoylphorbol Acetate - pharmacology | Concanavalin A - pharmacology | Cyclosporine - pharmacology | Humans | Middle Aged | Tumor Necrosis Factor-alpha - blood | Drug Monitoring - methods | Mycophenolic Acid - pharmacology | Tacrolimus - pharmacology | Adult | Immunosuppressive Agents - classification | Immunosuppressive Agents - pharmacology | Reproducibility of Results | Interleukin-2 Receptor alpha Subunit - blood | Receptors, Transferrin - blood | CD4-Positive T-Lymphocytes - cytology | CD4-Positive T-Lymphocytes - metabolism | Biomarkers - blood | Sirolimus - pharmacology | Antigens, CD - blood | Methylprednisolone - pharmacology | Lymphocyte Activation - drug effects | Cell Proliferation - drug effects | CD4-Positive T-Lymphocytes - drug effects | Interleukin-2 - blood | Lymphocyte receptors | Cell growth | Pharmacology | Inhibitor drugs | Drug therapy | Gene expression | Index Medicus
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9. Full Text Influence of anticancer agents on cell survival, proliferation, and CD4+CD25+Foxp3+ regulatory T cell-frequency in human peripheral-blood mononuclear cells activated by T cell-mitogen
by Tohyama, Naoya and Tanaka, Sachiko and Onda, Kenji and Sugiyama, Kentaro and Hirano, Toshihiko
International immunopharmacology, ISSN 1567-5769, 01/2013, Volume 15, Issue 1, pp. 160 - 166
T cell mitogen | Peripheral blood mononuclear cells | Anticancer agents | CD4+CD25+Foxp3+ regulatory T cells | Cytokine | regulatory T cells | CD4 | CD25 | Foxp3 | Pharmacology & Pharmacy | Immunology | Life Sciences & Biomedicine | Science & Technology | Methotrexate - pharmacology | Cell Survival - drug effects | Mitogens - pharmacology | Concanavalin A - pharmacology | Arsenicals - pharmacology | Humans | Male | T-Lymphocytes, Regulatory - immunology | Young Adult | Oxides - pharmacology | T-Lymphocytes, Regulatory - drug effects | Dacarbazine - pharmacology | Adolescent | Adult | Female | Leukocytes, Mononuclear - cytology | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | Fluorouracil - pharmacology | Immunosuppressive Agents - pharmacology | Cytokines - immunology | Index Medicus
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