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1. Full Text Nr5a1-Cre-mediated Tspo conditional knockout mice with low growth rate and prediabetes symptoms – A mouse model of stress diabetes
by Fan, Jinjiang and Campioli, Enrico and Papadopoulos, Vassilios
Biochimica et biophysica acta. Molecular basis of disease, ISSN 0925-4439, 01/2019, Volume 1865, Issue 1, pp. 56 - 62
Tspo | Conditional knockout | Nr5a1-Cre | Hyperglycemia | Low growth rate | Prediabetes | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Prediabetic State - metabolism | Receptors, GABA - genetics | Calgranulin A - metabolism | Cholesterol - blood | Humans | Liver - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Stress, Physiological | Blood Glucose | Male | Calgranulin A - genetics | Diabetes Mellitus, Type 2 - metabolism | Mitochondrial Proteins | Mice, Knockout | Animals | Mice - growth & development | Receptors, GABA - metabolism | Glucose - metabolism | Female | Integrases - metabolism | Steroidogenic Factor 1 - metabolism | Disease Models, Animal | Type 2 diabetes | Epinephrine | Medical research | Medical examination | Growth | Blood sugar | Liver | Genes | Cytochrome P-450 | Glycosylated hemoglobin | ACTH | Gene expression | Blood | Analysis | Medicine, Experimental | Prediabetic state | Protein binding
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2. Full Text An analysis of skeletal development in osteoblast‐specific and chondrocyte‐specific runt‐related transcription factor‐2 (Runx2) knockout mice
by Takarada, Takeshi and Hinoi, Eiichi and Nakazato, Ryota and Ochi, Hiroki and Xu, Cheng and Tsuchikane, Azusa and Takeda, Shu and Karsenty, Gerard and Abe, Takaya and Kiyonari, Hiroshi and Yoneda, Yukio
Journal of bone and mineral research, ISSN 0884-0431, 10/2013, Volume 28, Issue 10, pp. 2064 - 2069
OSTEOBLAST | SKELETOGENESIS | RUNX2 | CHONDROCYTE | CONDITIONAL KNOCKOUT | skeletogenesis | chondrocyte | osteoblast | conditional knockout | Runx2 | Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Phenotype | Animals | Core Binding Factor Alpha 1 Subunit - deficiency | Mice, Inbred C57BL | Female | Integrases - metabolism | Mice | Bone Development | Osteoblasts - metabolism | Core Binding Factor Alpha 1 Subunit - metabolism | Chondrocytes - metabolism | Mice, Knockout | Genetic research | Genetic engineering | Analysis | Collagen | Index Medicus
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3. Full Text Skeletal phenotype of the neuropeptide Y knockout mouse
by Wee, Natalie K.Y and Sinder, Benjamin P and Novak, Sanja and Wang, Xi and Stoddard, Chris and Matthews, Brya G and Kalajzic, Ivo
Neuropeptides (Edinburgh), ISSN 0143-4179, 02/2019, Volume 73, pp. 78 - 88
Conditional mouse | Neuropeptide Y (NPY) | Bone | Bone strength | Cortical bone | Endocrinology & Metabolism | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Neuropeptide Y - metabolism | Animals | Bone Density - physiology | Bone and Bones - metabolism | Alkaline Phosphatase - metabolism | Receptors, Neuropeptide Y - metabolism | Female | Male | Mice | Neuropeptide Y - genetics | Osteogenesis | Mice, Knockout | Neuropeptide Y | CRISPR | Alkaline phosphatase | Energy metabolism | Phenotypes | Femur | Osteocalcin | Adipose tissue | Transcription | Bone sialoprotein | Neuropeptides | Hypoxanthine phosphoribosyltransferase | Bone turnover | Bone mass | Clonal deletion | Stromal cells | Rodents | Bone marrow | Hypoxanthine | Phosphoribosyltransferase | Skeleton | Index Medicus | bone | neuropeptide Y (NPY) | conditional mouse | bone strength | cortical bone
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4. Full Text Forebrain-specific trkB-receptor knockout mice: behaviorally more hyperactive than “depressive”
by Zörner, Björn and Wolfer, David P and Brandis, Dorothee and Kretz, Oliver and Zacher, Christiane and Madani, Rime and Grunwald, Ilona and Lipp, Hans-Peter and Klein, Rüdiger and Henn, Fritz A and Gass, Peter
Biological psychiatry (1969), ISSN 0006-3223, 2003, Volume 54, Issue 10, pp. 972 - 982
depression model | HPA axis | trkB | Conditional knockout mice | behavior | Behavior | Depression model | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Psychiatry | Science & Technology | Methodology. Experimentation | Psychology. Psychoanalysis. Psychiatry | Techniques and methods | Adult and adolescent clinical studies | Psychopathology. Psychiatry | Mood disorders | Biological and medical sciences | Depression | Medical sciences | Immunohistochemistry | Depression - physiopathology | Psychomotor Agitation - genetics | Reaction Time | Receptor, trkB - genetics | Behavior, Animal | Depression - metabolism | Psychomotor Agitation - physiopathology | Time Factors | Stereotyped Behavior | Swimming | Corticosterone - blood | Prosencephalon - metabolism | Adrenocorticotropic Hormone - blood | Prosencephalon - physiopathology | Exploratory Behavior | Movement | Receptor, trkB - deficiency | Mice, Inbred C57BL | Mice, Transgenic | Corticotropin-Releasing Hormone - metabolism | Psychomotor Agitation - metabolism | Animals | Maze Learning | Analysis of Variance | Mice | Receptor, trkB - metabolism | Prosencephalon - anatomy & histology | Index Medicus
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5. Full Text Rapid and highly efficient inducible cardiac gene knockout in adult mice using AAV-mediated expression of Cre recombinase
by Werfel, Stanislas and Jungmann, Andreas and Lehmann, Lorenz and Ksienzyk, Jan and Bekeredjian, Raffi and Kaya, Ziya and Leuchs, Barbara and Nordheim, Alfred and Backs, Johannes and Engelhardt, Stefan and Katus, Hugo A and Müller, Oliver J
Cardiovascular research, ISSN 0008-6363, 10/2014, Volume 104, Issue 1, pp. 15 - 23
Serum response factor | Adeno-associated virus | Cardiomyopathy | Gene regulation | Conditional transgenic mouse | Serum Response Factor - genetics | Dependovirus - genetics | Ventricular Function, Left | Male | Integrases - biosynthesis | RNA, Messenger - metabolism | RNA, Untranslated - genetics | Gene Knockdown Techniques | Cardiomyopathies - genetics | Cardiomyopathies - physiopathology | Time Factors | Ventricular Dysfunction, Left - genetics | Ventricular Dysfunction, Left - pathology | Troponin T - genetics | Promoter Regions, Genetic | Serum Response Factor - metabolism | Down-Regulation | Mice, Inbred C57BL | Cardiomyopathies - pathology | Genotype | Ventricular Dysfunction, Left - physiopathology | Mice, Knockout | Ventricular Dysfunction, Left - metabolism | Myocytes, Cardiac - pathology | Phenotype | Animals | Cardiomyopathies - metabolism | Fibrosis | Myocytes, Cardiac - metabolism | Dependovirus - enzymology | Integrases - genetics | Lac Operon | Index Medicus
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6. Full Text Effects of tissue-specific GH receptor knockouts in mice
by List, Edward O and Duran-Ortiz, Silvana and Kopchick, John J
Molecular and cellular endocrinology, ISSN 0303-7207, 09/2020, Volume 515, pp. 110919 - 110919
GHR | Conditional knockout | Gene disruption | Tissue-specific knockout | GHRKO | Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Biotechnology | Pancreatic beta cells | Pituitary hormones | Neurons | Analysis | Leptin | Genetically modified organisms | Genetic engineering | Glucose | Dextrose | Index Medicus
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7. Full Text Raphe serotonin neuron‐specific oxytocin receptor knockout reduces aggression without affecting anxiety‐like behavior in male mice only
by Pagani, J. H and Williams Avram, S. K and Cui, Z and Song, J and Mezey, É and Senerth, J. M and Baumann, M. H and Young, W. S
Genes, brain and behavior, ISSN 1601-1848, 02/2015, Volume 14, Issue 2, pp. 167 - 176
Conditional knockout | oxytocin | serotonin | maternal aggression | Maternal aggression | Oxytocin | Serotonin | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Behavioral Sciences | Science & Technology | Aggression - physiology | Receptors, Oxytocin - deficiency | Receptors, Oxytocin - genetics | Male | Maternal Behavior - physiology | Sex Characteristics | Oxytocin - metabolism | Mice, Knockout | Behavior, Animal | Serotonin Plasma Membrane Transport Proteins - metabolism | Receptors, Oxytocin - metabolism | Animals | Serotonin - metabolism | Female | Neurons - metabolism | Anxiety - metabolism | Physiological aspects | Phenols | Pituitary hormones | Neurons | Behavior | Anxieties | Rodents | Index Medicus | conditional knockout
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8. Full Text Impairment of photoreceptor ribbon synapses in a novel Pomt1 conditional knockout mouse model of dystroglycanopathy
by Rubio-Fernández, Marcos and Uribe, Mary Luz and Vicente-Tejedor, Javier and Germain, Francisco and Susín-Lara, Cristina and Quereda, Cristina and Montoliu, Lluis and De La Villa, Pedro and Martín-Nieto, José and Cruces, Jesús
Scientific reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 8543 - 15
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Electroretinography | Dystroglycans - metabolism | Glycosylation | Synapses - genetics | Walker-Warburg Syndrome - genetics | Mannosyltransferases - genetics | Retinal Rod Photoreceptor Cells - metabolism | Synapses - pathology | Mice, Knockout | Animals | Synapses - metabolism | Walker-Warburg Syndrome - metabolism | Retinal Cone Photoreceptor Cells - pathology | Dystroglycans - genetics | Mannosyltransferases - metabolism | Mice | Retinal Cone Photoreceptor Cells - metabolism | Retinal Rod Photoreceptor Cells - pathology | Walker-Warburg Syndrome - pathology | Dystroglycan | Dolichyl-phosphate-mannose-protein mannosyltransferase | Exons | Retina | Rods | Recombinase | Protein deficiency | CRX protein | Cre recombinase | Optokinetic response | Homeobox | Laminin | Clonal deletion | Cones | Bipolar cells | Photoreceptors | Synaptic ribbons | Index Medicus
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9. Full Text Generation and Characterization of Fibroblast-Specific Basigin Knockout Mice
by Wu, Xiao-Dong and Wu, Xiao-Dong and Zhang, Meng-Yao and Zhang, Meng-Yao and Chen, Ya-Tong and Chen, Ya-Tong and Yao, Hui and Yao, Hui and Zhang, Qing and Zhang, Qing and Wang, Wen-Jing and Wang, Wen-Jing and Fu, Da-Fu and Fu, Da-Fu and Wei, Ren-Ji and Wei, Ren-Ji and Zhang, Jia-Yu and Zhang, Jia-Yu and Li, Yin and Li, Yin and Dang, Dan and Dang, Dan and Bian, Hui-Jie and Bian, Hui-Jie and Xu, Jing and Xu, Jing and Chen, Zhi-Nan and Chen, Zhi-Nan
Molecular biotechnology, ISSN 1073-6085, 2/2019, Volume 61, Issue 2, pp. 111 - 121
Biochemistry, general | Protein Science | Human Genetics | Basigin | Biotechnology | Chemistry | Biological Techniques | Cre-loxp | Fibroblast | Conditional gene knockout mice | Cell Biology | Apoptosis | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Liver | Analysis | Cells | Index Medicus
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10. Full Text Residual microRNA expression dictates the extent of inner ear development in conditional Dicer knockout mice
by Soukup, Garrett A and Fritzsch, Bernd and Pierce, Marsha L and Weston, Michael D and Jahan, Israt and McManus, Michael T and Harfe, Brian D
Developmental biology, ISSN 0012-1606, 04/2009, Volume 328, Issue 2, pp. 328 - 341
Floxed Dicer | RNA interference | MicroRNA | Hair cell | Inner ear development | Conditional knockout | Sensory epithelium | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Hair Cells, Auditory - cytology | Cochlea - embryology | Ear, Inner - innervation | Endoribonucleases - genetics | Fibroblast Growth Factor 10 - metabolism | Ear, Inner - embryology | Ear, Inner - cytology | Epithelium - innervation | MicroRNAs - biosynthesis | Cochlea - cytology | Cochlea - innervation | Endoribonucleases - physiology | Mice, Knockout | Organogenesis | DEAD-box RNA Helicases - genetics | DEAD-box RNA Helicases - physiology | Epithelium - embryology | Animals | Ribonuclease III | Ear, Inner - abnormalities | Cell Differentiation | Mice | RNA | Fibroblast growth factors | Index Medicus | floxed Dicer | sensory epithelium | hair cell | microRNA | inner ear development | conditional knockout
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