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Journal of Neurochemistry, ISSN 0022-3042, 09/2011, Volume 118, Issue 5, pp. 826 - 840
Inflammation contributes to neurodegeneration in post-ischemic brain, diabetes, and Alzheimer's disease. Participants in this inflammatory response include... 
gap junctions | Alzheimer’s disease | amyloid β‐peptide | cytokines | diabetes mellitus | pannexin | stroke | connexin | amyloid β-peptide | Alzheimer's disease | BRAIN-INJURY | GAP JUNCTIONAL COMMUNICATION | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | AMYLOID PLAQUES | ASTROCYTES | NEUROTOXICITY | NEUROSCIENCES | BETA | IN-VIVO | CHANNELS | RECEPTORS | amyloid beta-peptide | Tumor Necrosis Factor-alpha - metabolism | Oxygen - pharmacology | Cell Hypoxia - physiology | Amyloid beta-Peptides - pharmacology | Microtubule-Associated Proteins - pharmacology | Culture Media, Conditioned - pharmacology | Lanthanum - pharmacology | Peptide Fragments - pharmacology | Cerebral Cortex - cytology | Adenosine Triphosphate - pharmacology | Time Factors | Interleukin-1beta - metabolism | Adenosine Triphosphate - metabolism | Neuropeptides - pharmacology | Nerve Tissue Proteins - pharmacology | Neurons - physiology | Astrocytes - chemistry | Female | Cell Death - drug effects | Connexins - pharmacology | Neurons - drug effects | Animals, Newborn | Astrocytes - drug effects | Cell Hypoxia - drug effects | Connexin 43 - metabolism | Glutamic Acid - pharmacology | Cells, Cultured | Fluoresceins | Coculture Techniques - methods | Connexin 43 - deficiency | Connexins - metabolism | Mice, Knockout | Nerve Tissue Proteins - metabolism | Animals | Biotinylation - methods | Glutamic Acid - metabolism | Mice | Astrocytes - metabolism | Methyl aspartate | Neurosciences | Peptides | Neurons | Diabetes | Glucose | Glutamate | Dextrose | Index Medicus
Journal Article
Circulation Research, ISSN 0009-7330, 10/2004, Volume 95, Issue 7, pp. 726 - 733
Altered gap junction coupling of cardiac myocytes during ischemia may contribute to development of lethal arrhythmias. The phosphoprotein connexin 43 (Cx43) is... 
Ischemia | Gap junctions | Glycolysis | Okadaic acid | Protein phosphatases | Connexin43 | Protein phosphorylation | AMP kinase | gap junctions | PROTEIN-KINASE-C | CARDIAC & CARDIOVASCULAR SYSTEMS | connexin43 | PHOSPHORYLATION | GAP JUNCTIONAL COMMUNICATION | glycolysis | CARDIAC MYOCYTES | ACTIN GENE | protein phosphorylation | okadaic acid | ischemia | IN-VITRO | INTERCELLULAR COMMUNICATION | PERIPHERAL VASCULAR DISEASE | JUN KINASE | protein phosphatases | RAT VENTRICULAR MYOCYTES | HEMATOLOGY | ADRENERGIC REGULATION | Okadaic Acid - pharmacology | Tetradecanoylphorbol Acetate - pharmacology | Maleimides - pharmacology | Recombinant Fusion Proteins - physiology | Myocardial Contraction - drug effects | Brefeldin A - pharmacology | Phenanthridines - pharmacology | Antimycin A - pharmacology | Aminoimidazole Carboxamide - pharmacology | Cell Hypoxia | Ribonucleotides - pharmacology | Alkaloids | Protein Processing, Post-Translational - drug effects | Adenosine Triphosphate - metabolism | Deoxyglucose - pharmacology | Tacrolimus - pharmacology | Indoles - pharmacology | Flavonoids - pharmacology | Potassium Cyanide - pharmacology | JNK Mitogen-Activated Protein Kinases - genetics | Phosphorylation - drug effects | Ouabain - pharmacology | Cells, Cultured - drug effects | Connexin 43 - metabolism | Rats | Imidazoles - pharmacology | Cycloheximide - pharmacology | Pyrroles - pharmacology | Animals | Myocytes, Cardiac - drug effects | Aminoimidazole Carboxamide - analogs & derivatives | Benzophenanthridines | JNK Mitogen-Activated Protein Kinases - physiology | Myocytes, Cardiac - metabolism | Cells, Cultured - metabolism | Pyridines - pharmacology | Carbazoles - pharmacology | Staurosporine - pharmacology | Index Medicus
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 09/2008, Volume 295, Issue 3, pp. 752 - 760
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 06/2014, Volume 171, Issue 11, pp. 2751 - 2766
Background and PurposeCardiovascular risk is higher in men and postmenopausal women compared with premenopausal women. This may be due to sex differences in... 
gap junctions | nitric oxide | hydrogen peroxide | EDH | channel | bradykinin | SKc | endothelium‐derived hyperpolarization | PCA | porcine coronary artery | small‐conductance calcium‐activated | sex differences | connexin | intermediate‐conductance calcium‐activated | porcine coronary artery (PCA) | nitric oxide (NO) | connexin (Cx) | endothelium-derived hyperpolarization (EDH) | small-conductance calcium-activated K+ channel (SKc(a)) | MESENTERIC-ARTERIES | CA2+-ACTIVATED K+ CHANNELS | ACTIVATED POTASSIUM CHANNELS | intermediate-conductance calcium-activated K+ channel (IKca) | HYPERPOLARIZING FACTOR | NITRIC-OXIDE | hydrogen peroxide (H2O2) | PHARMACOLOGY & PHARMACY | PIG CAROTID-ARTERY | HYDROGEN-PEROXIDE | DEPENDENT RELAXATIONS | GENDER-DIFFERENCES | SMALL-CONDUCTANCE | Catalase - pharmacology | NG-Nitroarginine Methyl Ester - pharmacology | Vasoconstrictor Agents - pharmacology | Vasodilator Agents - pharmacology | Coronary Vessels - physiology | Glycyrrhetinic Acid - analogs & derivatives | Hydrogen Peroxide - pharmacology | Male | Sex Characteristics | Apamin - pharmacology | Indomethacin - pharmacology | Vasodilation | Connexins - metabolism | Endothelium, Vascular - physiology | Carbenoxolone - pharmacology | Glycyrrhetinic Acid - pharmacology | Animals | Gap Junctions - physiology | Swine | 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid - pharmacology | Female | Bradykinin - pharmacology | Polyethylene Glycols - pharmacology | Pyrazoles - pharmacology | Postmenopausal women | Hydrogen peroxide | Nitric oxide | Arteries | Endothelium | Index Medicus | Research Papers | small-conductance calcium-activated K+ channel (SKca)
Journal Article
Neuropharmacology, ISSN 0028-3908, 10/2015, Volume 97, pp. 133 - 141
Anticancer therapy based on the repeated administration of oxaliplatin is limited by the development of a neuropathic syndrome difficult to treat. Oxaliplatin... 
Chemotherapy-induced neuropathy | Synaptosome | Oxaliplatin | P2X7 | Pannexin 1 | ANTERIOR CINGULATE CORTEX | RAT | INDUCED PERIPHERAL NEUROPATHY | SPINAL-CORD | PORE FORMATION | CANCER | NEUROSCIENCES | P2X7 RECEPTOR | CEREBROCORTICAL NERVE-TERMINALS | P2X RECEPTORS | PHARMACOLOGY & PHARMACY | ATP RELEASE | Analgesics - pharmacology | Connexins - antagonists & inhibitors | Synaptosomes - drug effects | Tetrazoles - pharmacology | Colonic Neoplasms - drug therapy | Humans | Neuralgia - metabolism | Male | Purinergic P2X Receptor Antagonists - pharmacology | Synaptosomes - metabolism | Cerebral Cortex - metabolism | Colonic Neoplasms - metabolism | Organoplatinum Compounds - pharmacology | Antineoplastic Agents - toxicity | Benzenesulfonates - pharmacology | Neuralgia - chemically induced | Antineoplastic Agents - pharmacology | Cell Death - drug effects | Cerebral Cortex - drug effects | Nerve Tissue Proteins - antagonists & inhibitors | Rosaniline Dyes - pharmacology | Rats, Sprague-Dawley | Connexins - metabolism | Nerve Tissue Proteins - metabolism | Carbenoxolone - pharmacology | Organoplatinum Compounds - toxicity | Animals | Cell Death - physiology | Cell Line, Tumor | Receptors, Purinergic P2X7 - metabolism | Glutamic Acid - metabolism | Pyridines - pharmacology | Brain | Neurosciences | Colon cancer | Glutamate | Analysis | Index Medicus
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 03/2010, Volume 30, Issue 12, pp. 4197 - 4209
During mitotic division in the telencephalic proliferative ventricular zone (VZ), the nuclei of the neural precursors move basally away from the ventricular... 
NEURONAL MIGRATION | EMBRYONIC NEOCORTEX | VENTRICULAR ZONE | DEVELOPING NEOCORTEX | CALCIUM WAVES | MOUSE NEOCORTEX | SUBVENTRICULAR ZONE | JUNCTION HEMICHANNELS | CONNEXIN HEMICHANNELS | NEUROSCIENCES | CYTOCHALASIN-B | Meclofenamic Acid - pharmacology | Calcium - metabolism | Embryo, Mammalian | Ki-67 Antigen - metabolism | Green Fluorescent Proteins - genetics | Stem Cells - cytology | Neuroblastoma | Cell Movement - physiology | Patch-Clamp Techniques - methods | Adenosine Triphosphate - pharmacology | Cell Nucleus - metabolism | Adenosine Triphosphate - metabolism | Egtazic Acid - analogs & derivatives | Neurons - physiology | Platelet Aggregation Inhibitors - pharmacology | Female | Bromodeoxyuridine - metabolism | Pyridoxal Phosphate - analogs & derivatives | Neurons - drug effects | Organ Culture Techniques | Connexin 43 - genetics | Boron Compounds - pharmacology | Green Fluorescent Proteins - metabolism | Pyridoxal Phosphate - pharmacology | Connexin 43 - metabolism | 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid - pharmacology | Chelating Agents - pharmacology | Cyclooxygenase Inhibitors - pharmacology | Pregnancy | Carbenoxolone - pharmacology | Cell Movement - drug effects | Animals | Egtazic Acid - pharmacology | Gap Junctions - physiology | Calcium Signaling - drug effects | Prosencephalon - cytology | Cell Line, Tumor | Mice | Cell Nucleus - drug effects | Cerebral Ventricles - cytology | Gap Junctions - drug effects | Index Medicus | Interkinetic nuclear migration | Hemichannel | Subventricular zone | Ventricular zone | Gap junction | Neuronal progenitor
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 09/2013, Volume 288, Issue 38, pp. 27571 - 27583
Changes in the regulation of connective tissue ATP-mediated mechano-transduction and remodeling may be an important link to the pathogenesis of chronic pain.... 
CARDIAC FIBROBLASTS | LOW-BACK-PAIN | EPITHELIAL-CELLS | COLLAGEN-SYNTHESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ADENOSINE | OSTEOGENIC DIFFERENTIATION | CHANNELS | RECEPTORS | MARROW STROMAL CELLS | CONNECTIVE-TISSUE | Connexins - antagonists & inhibitors | Calcium - metabolism | Humans | Middle Aged | Adenosine Triphosphate - secretion | Brefeldin A - pharmacology | Male | Exocytosis - physiology | Exocytosis - drug effects | Histamine - metabolism | Histamine Agonists - metabolism | Receptors, Histamine H1 - metabolism | Receptors, Purinergic P2Y1 - metabolism | Mast Cells - metabolism | Female | Fibroblasts - metabolism | Mefloquine - pharmacology | Purinergic P2Y Receptor Antagonists - pharmacology | Nerve Tissue Proteins - antagonists & inhibitors | Histamine - pharmacology | Cells, Cultured | Gene Expression Regulation - physiology | Octanols - pharmacology | Adenosine Diphosphate - pharmacology | Antimalarials - pharmacology | Connexins - metabolism | Gene Expression Regulation - drug effects | Nerve Tissue Proteins - metabolism | Collagen Type I - biosynthesis | Mast Cells - cytology | Adenosine Diphosphate - secretion | Anti-Bacterial Agents - pharmacology | Cell Proliferation - drug effects | Fibroblasts - cytology | Histamine Agonists - pharmacology | Adenosine Diphosphate - analogs & derivatives | Index Medicus | Purinergic Receptor | Calcium | Pannexin | Human Subcutaneous Fibroblasts | Nucleoside Nucleotide Metabolism | ATP Release | Mechanotransduction | ATPases | ADP | ATP | Cell Biology
Journal Article
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, ISSN 0363-6143, 09/2008, Volume 295, Issue 3, pp. C752 - C760
Pannexin 1 (Panx1), an ortholog to invertebrate innexin gap junctions, has recently been proposed to be the pore induced by P2X(7) receptor (P2X(7)R)... 
P-2Z | EXTRACELLULAR ATP | PHYSIOLOGY | src-tyrosine kinase | ATP-INDUCED PORE | GAP-JUNCTION PROTEINS | gap junction blockers | permeabilization | CONNEXIN HEMICHANNELS | PHOSPHOLIPASE-D ACTIVATION | CELL BIOLOGY | P2X7 RECEPTOR | XENOPUS-OOCYTES | INTERLEUKIN-1-BETA RELEASE | CELL-CELL COMMUNICATION | FUNCTIONAL EVIDENCE
Journal Article
The Journal of Physiology, ISSN 0022-3751, 05/2004, Volume 556, Issue 3, pp. 875 - 886
A role for myoendothelial gap junctions (MEGJs) has been proposed in the action of the vasodilator endothelium-derived hyperpolarizing factor (EDHF). EDHF... 
SMOOTH-MUSCLE | PHYSIOLOGY | MESENTERIC-ARTERIES | POTASSIUM CHANNELS | ENDOTHELIUM-DEPENDENT HYPERPOLARIZATION | HYPERTENSIVE RATS | GUINEA-PIG | CONNEXIN EXPRESSION | CORONARY-ARTERIES | SMALL-CONDUCTANCE | EDHF-TYPE RELAXATIONS | Catalase - pharmacology | Endothelium, Vascular - cytology | Immunohistochemistry | Rats, Inbred WKY | Male | Peptide Fragments - pharmacology | Apamin - pharmacology | Endothelium, Vascular - physiology | 8,11,14-Eicosatrienoic Acid - analogs & derivatives | Phenylephrine - pharmacology | Arteries - physiology | Charybdotoxin - pharmacology | Vasodilation - physiology | 8,11,14-Eicosatrienoic Acid - pharmacology | Connexins - pharmacology | Myocytes, Smooth Muscle - drug effects | Hydroxocobalamin - pharmacology | Ouabain - pharmacology | Connexins - chemistry | Pyrazoles - pharmacology | Membrane Potentials - drug effects | NG-Nitroarginine Methyl Ester - pharmacology | Acetylcholine - pharmacology | Biological Factors - physiology | Myocytes, Smooth Muscle - physiology | Rats | Arteries - drug effects | Barium - pharmacology | Femoral Artery - drug effects | Microscopy, Electron | Indomethacin - pharmacology | Connexin 26 | Gap Junctions - ultrastructure | Patch-Clamp Techniques | Animals | Gap Junctions - physiology | Models, Biological | Femoral Artery - physiology | Vasodilation - drug effects | In Vitro Techniques | Index Medicus | Research Papers
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 12/2009, Volume 111, Issue 6, pp. 1383 - 1397
Brain injuries as well as neurodegenerative diseases, are associated with neuro-inflammation characterized by astroglial and microglial activation and/or... 
Methanandamide | Reactive gliosis | Neuroinflammation | Cytokines | Astrocytes | Microglia | IMMUNE MODULATION | SELECTIVE ANTAGONIST | reactive gliosis | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOCANNABINOID SYSTEM | CORTICAL ASTROCYTES | NEUROSCIENCES | methanandamide | CB2 RECEPTORS | NITRIC-OXIDE PRODUCTION | MULTIPLE-SCLEROSIS | neuroinflammation | REACTIVE ASTROCYTES | cytokines | astrocytes | microglia | RAT MICROGLIAL CELLS | COMMUNICATION | Enzyme-Linked Immunosorbent Assay - methods | Tumor Necrosis Factor-alpha - metabolism | Analgesics - pharmacology | Cannabinoids - antagonists & inhibitors | Culture Media, Conditioned - pharmacology | Ethidium - metabolism | Cerebral Cortex - cytology | Drug Interactions | Piperidines - pharmacology | Interleukin-1beta - metabolism | Cyclohexanols - pharmacology | Cannabinoids - metabolism | Pyrazoles - pharmacology | Animals, Newborn | Astrocytes - drug effects | Connexin 43 - metabolism | Cells, Cultured | Morpholines - pharmacology | Arachidonic Acids - pharmacology | Cannabinoids - pharmacology | Connexins - metabolism | Microglia - chemistry | Naphthalenes - pharmacology | Gene Expression Regulation - drug effects | Maximum Tolerated Dose | Animals | Benzoxazines - pharmacology | Lipopolysaccharides - pharmacology | Mice | Astrocytes - metabolism | Brain damage | Inflammatory diseases | Index Medicus
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 03/2012, Volume 302, Issue 6, pp. 915 - 923
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 05/2003, Volume 23, Issue 9, pp. 3588 - 3596
Journal Article
Journal Article
Glia, ISSN 0894-1491, 05/2015, Volume 63, Issue 5, pp. 795 - 811